Obinutuzumab With or Without Umbralisib, Lenalidomide, or Combination Chemotherapy in Treating Patients With Relapsed or Refractory Grade I-IIIa Follicular Lymphoma
Study Details
Study Description
Brief Summary
This phase II trial studies how well obinutuzumab with or without umbralisib, lenalidomide, or combination chemotherapy work in treating patients with grade I-IIIa follicular lymphoma that has come back (relapsed) or does not respond to treatment (refractory). Immunotherapy with obinutuzumab, may induce changes in body's immune system and may interfere with the ability of tumor cells to grow and spread. Umbralisib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Biological therapies, such as lenalidomide, use substances made from living organisms that may stimulate or suppress the immune system in different ways and stop cancer cells from growing. Chemotherapy drugs, such as cyclophosphamide, doxorubicin, vincristine, prednisone, and bendamustine, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. It is not yet known whether giving obinutuzumab with or without umbralisib, lenalidomide, or combination chemotherapy will work better in treating patients with grade I-IIIa follicular lymphoma.
Condition or Disease | Intervention/Treatment | Phase |
---|---|---|
|
Phase 2 |
Detailed Description
PRIMARY OBJECTIVE:
- To compare the complete response rate up to 6 cycles after randomization as defined by centrally read positron emission tomography (PET)/computed tomography (CT) (integral biomarker) of 2 targeted therapeutic regimens (obinutuzumab + umbralisib [TGR-1202] or obinutuzumab + lenalidomide) with obinutuzumab + chemotherapy (cyclophosphamide, doxorubicin hydrochloride [doxorubicin], vincristine sulfate [vincristine], and prednisone [CHOP] or bendamustine hydrochloride [bendamustine]) in patients with early relapsing or refractory follicular lymphoma.
SECONDARY OBJECTIVES:
-
To validate the prognostic association of the m7-FLIPI model, demonstrating that the population of follicular lymphoma patients who respond poorly to chemoimmunotherapy are enriched for having a high-risk m7-FLIPI score, and that the score is associated with progression-free survival (integrated biomarker). (Primary translational medicine) II. To estimate the 30-month sustained complete response rate (CR30) defined by centrally read PET/CT with each of the regimens in this early relapsing or refractory follicular lymphoma population.
-
To estimate best response up to 12 cycles of therapy, progression free survival, duration of response and overall survival with each of the combinations in early relapsing or refractory follicular lymphoma.
-
To evaluate the adverse effects of each of the regimens in early relapsing or refractory follicular lymphoma.
-
To evaluate the predictive performance of non-invasive genotyping (m7-FLIPI in circulating tumor deoxyribonucleic acid [DNA]) of plasma at study entry relative to standard tumor genotyping (m7-FLIPI) of formalin-fixed paraffin-embedded tumor tissue.
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To evaluate the association between the detection of active lymphoma by PET-CT and the detection of circulating tumor DNA in plasma at baseline, after 6 and 12 cycles, and at 30 months after initiation of study therapy.
OUTLINE: Patients are randomized to 1 of 3 arms.
ARM I: Patients receive obinutuzumab intravenously (IV) on day 1 and umbralisib orally (PO) daily on days 1-28. Treatment repeats every 28 days for up to 12 cycles in the absence of disease progression or unacceptable toxicity.
ARM II: Patients receive obinutuzumab IV on day 1 and lenalidomide PO on days 1-21. Treatment repeats every 28 days for up 12 cycles in the absence of disease progression or unacceptable toxicity.
ARM III:
PRIOR BENDAMUSTINE-BASED CHEMOTHERAPY: Patients receive obinutuzumab IV on day 1, cyclophosphamide IV on day 1, doxorubicin IV on day 1, vincristine IV on day 1, and prednisone PO on days 1-5. Treatment with obinutuzumab repeats every 21 or 28 days for up to 12 cycles in the absence of disease progression or unacceptable toxicity. Treatment with combination chemotherapy repeats every 21 days for 6 cycles in the absence of disease progression or unacceptable toxicity.
PRIOR CHOP CHEMOTHERAPY: Patients receive obinutuzumab IV on day 1 and bendamustine IV over 60 minutes on days 1 and 2. Treatment repeats every 28 days for up to 6 or 12 cycles (bendamustine and obinutuzumab, respectively) in the absence of disease progression or unacceptable toxicity.
After completion of study treatment, patients are followed up every 3 months for 2 years and then every 6 months for 3 years.
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
---|---|
Experimental: Arm I (obinutuzumab, umbralisib) Patients receive obinutuzumab IV on day 1 and umbralisib PO daily on days 1-28. Treatment repeats every 28 days for up to 12 cycles in the absence of disease progression or unacceptable toxicity. |
Biological: Obinutuzumab
Given IV
Other Names:
Drug: Umbralisib
Given PO
Other Names:
|
Experimental: Arm II (obinutuzumab, lenalidomide) Patients receive obinutuzumab IV on day 1 and lenalidomide PO on days 1-21. Treatment repeats every 28 days for up to 12 cycles in the absence of disease progression or unacceptable toxicity. |
Drug: Lenalidomide
Given PO
Other Names:
Biological: Obinutuzumab
Given IV
Other Names:
|
Active Comparator: Arm III (obinutuzumab, combination chemotherapy) PRIOR BENDAMUSTINE-BASED CHEMOTHERAPY: Patients receive obinutuzumab IV on day 1, cyclophosphamide IV on day 1, doxorubicin IV on day 1, vincristine IV on day 1, and prednisone PO on days 1-5. Treatment with obinutuzumab repeats every 21 or 28 days for up to 12 cycles in the absence of disease progression or unacceptable toxicity. Treatment with combination chemotherapy repeats every 21 days for up to 6 cycles in the absence of disease progression or unacceptable toxicity. PRIOR CHOP CHEMOTHERAPY: Patients receive obinutuzumab IV on day 1, and bendamustine IV over 1 hour on days 1 and 2. Treatment repeats every 28 days for up to 6 or 12 cycles (bendamustine and obinutuzumab, respectively) in the absence of disease progression or unacceptable toxicity. |
Drug: Bendamustine Hydrochloride
Given IV
Other Names:
Drug: Cyclophosphamide
Given IV
Other Names:
Drug: Doxorubicin Hydrochloride
Given IV
Other Names:
Biological: Obinutuzumab
Given IV
Other Names:
Drug: Prednisone
Given PO
Other Names:
Drug: Vincristine Sulfate
Given IV
Other Names:
|
Outcome Measures
Primary Outcome Measures
- Complete response (CR) [Up to 6 cycles]
Secondary Outcome Measures
- Sustained complete response rate (CR30) [Up to 30 months]
Defined by centrally read positron emission tomography (PET)/computed tomography (CT).
- Progression-free survival (PFS) [From date of registration to date of first observation of progressive disease, or death due to any cause, assessed up to 5 years]
Will be calculated using the method of Kaplan-Meier. 95% confidence for the survival estimates will be constructed using the method of Brookmeyer-Crowley. With 31 eligible patients in each arm, progression free survival at a particular time point, and the 30-month sustained response rate can be estimated to within at least +/- 18% with 95% confidence.
- Duration of response (CR, partial response [PR]) [From date of first documentation of response to treatment (CR, PR) to date of first documentation of progression, or death due to any cause, assessed up to 5 years]
Will be calculated using the method of Kaplan-Meier.
- Overall survival (OS) [Up to 5 years]
Will be calculated using the method of Kaplan-Meier. 95% confidence for the survival estimates will be constructed using the method of Brookmeyer-Crowley. With 31 eligible patients in each arm, OS at a particular time point, and the 30-month sustained response rate can be estimated to within at least +/- 18% with 95% confidence.
- Incidence of adverse events [Up to 5 years]
Assessed by National Cancer Institute Common Terminology Criteria for Adverse Events (CTCAE) version 4.0 (version 5.0 will be utilized for serious adverse events reporting only). Toxicity rates can be estimated to within at least +/- 18% with 95% confidence.
- Non-invasive genotyping and circulating tumor deoxyribonucleic acid (DNA) assessment [Up to 5 years]
Sensitivity, specificity, positive predictive value, negative predictive value, and kappa coefficient will be used to evaluate the concordance. Will evaluate the association of detection of active lymphoma by positron emission tomography-computed tomography and the detection of circulating tumor DNA in plasma at baseline, after 6 and 12 cycles, and at 30 months after initiation of study therapy. Chi-square test will be used to evaluate the association and odds ratio will be calculated
- Active lymphoma and circulating tumor DNA in plasma [From baseline up to 30 months after initiation of treatment]
The Cox proportional hazards model will be used to assess the association and odds ratio will be calculated.
- m7-FLIPI model validation [Up to 5 years]
The Cox proportional hazards model will be used to assess the association of the m7-FLIPI with to PFS.
Eligibility Criteria
Criteria
Inclusion Criteria:
-
Patients must have follicular lymphoma (grade I, II or IIIa) confirmed at initial diagnosis and at relapse with identifiable fludeoxyglucose F-18 (FDG) avid disease on PET/CT; patients that have involvement with large cell lymphoma are not eligible
-
Patients must not have clinical evidence of central nervous system involvement by lymphoma since the proposed treatment strategies are not designed to address central nervous system (CNS) involvement adequately; if performed, any laboratory or radiographic tests performed to assess CNS involvement must be negative
-
Patients must have a whole body or limited whole body PET/CT scan performed within 42 days prior to registration
-
Patients must have bone marrow biopsy performed within 42 days prior to registration
-
All disease must be assessed and documented on the S1608 FDG-PET/CT assessment form
-
The intent is to enroll patients with FL relapsed within 2 years of completing their first course of chemotherapy (CHOP or bendamustine based therapy) + anti-CD20 therapy. Patient is still eligible if he/she received radiation therapy or anti-CD20 therapy prior to chemoimmunotherapy or if maintenance anti-CD20 therapy was administered after chemoimmunotherapy
-
Patients must have either failed to achieve a complete remission, or must have relapsed within 2 years after completing CHOP or bendamustine-containing chemoimmunotherapy (including an anti-CD20 monoclonal antibody), as measured from the last dose of CHOP or bendamustine; relapsed patients must not have received any intervening chemotherapy
-
Patients must have received only 1 course of chemotherapy, containing at least 3 cycles of CHOP or bendamustine; (note that no minimum dose of bendamustine is required)
-
Patients who received any anti-CD20 antibody therapy prior to CHOP or bendamustine are eligible
-
Patients who additionally received any maintenance anti-CD-20 antibody therapy or consolidative radioimmunotherapy within 2 years of the last dose of the CHOP or bendamustine therapy are eligible
-
Involved field or involved site radiation is not considered a line of therapy; examples of eligible prior treatment regimens (note this list is not all inclusive):
-
1st line rituximab treatment followed years later by bendamustine rituximab x 4 cycles
-
Bendamustine rituximab x 4 cycles
-
1st line rituximab treatment, 2nd line ibritumomab tiuxetan, followed by bendamustine bortezomib rituximab x 6 cycles followed by rituximab maintenance
-
Bendamustine obinutuzumab x 3 cycles
-
CHOP rituximab x 6 cycles followed by rituximab maintenance
-
For all forms of systemic therapy, patients must have completed therapy at least 21 days prior to registration; patients must have completed any radioimmunotherapy at least 84 days prior to registration; patients prior treatment related toxicities (except alopecia) must have resolved to Grade 1 or less prior to registration
-
Patients must not have any prior treatment with any PI3K inhibitor, or lenalidomide
-
Patients must have tissue specimens collected prior to registration; patients must be offered participation in biobanking of residual specimens; with patient consent, residuals from the mandatory submission will be banked for future research
-
Patients must be >= 18 years of age
-
All patients must have a Zubrod performance status of 0, 1 or 2
-
Absolute neutrophil count (ANC) >= 1,500/mcL within 28 days prior to registration
-
Platelets >= 75,000/mcL within 28 days prior to registration
-
Patients must have adequate renal function as documented by a calculated creatinine clearance >= 60 mL/min, within 28 days prior to registration
-
Total bilirubin =< 1.5 x institutional upper limit of normal (IULN) (=< 5 x IULN if secondary to lymphoma, Gilbert's syndrome, or medication related [e.g., indinavir, tenofovir, atazanavir]) within 28 days prior to registration
-
Direct bilirubin =< 1.5 x IULN (=< 5 x IULN if secondary to lymphoma) within 28 days prior to registration
-
Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) =< 2.5 x IULN (=< 5 x IULN secondary to lymphoma) within 28 days prior to registration
-
Patients must have an echocardiogram (ECHO) or multigated acquisition (MUGA) scan within 42 days prior to registration with a cardiac ejection fraction >= 45%
-
Patients with hepatitis B virus infection must have undetectable hepatitis B virus (HBV) on suppressive therapy and no evidence of HBV-related hepatic damage; patients with hepatitis C virus infection are eligible if complete eradication therapy has been successfully completed, and there is no detectable hepatitis C virus (HVC) or related hepatic damage; patients with known human immunodeficiency virus (HIV) infection are eligible if they meet all of the following criteria in addition to the other protocol eligibility criteria:
-
Patient must have no history of acquired immune deficiency syndrome (AIDS)-related complications, other than a history of low CD4+ T-cell count (< 200/mm^3) prior to initiation of combination antiretroviral therapy; on study CD4+ T-cell count may not be informative due to leukemia and should not be used as an exclusion criterion if low
-
Patient must be healthy on the basis of HIV disease with high likelihood of near normal life span were it not for the leukemia
-
Patient must have serum HIV viral load of < 200 copies/mm^3
-
Patient must be on combination antiretroviral therapy with minimal pharmacokinetic interactions with study therapy and minimal overlapping clinical toxicity with protocol therapy; (recommend a regimen of the integrase inhibitor dolutegravir combined with either disoproxil fumarate/emtricitabine or dolutegravir combined with tenofovir alafenamide/emtricitabine)
-
Protease inhibitors and once daily formulations containing cobicistat are NOT allowed due to potential pharmacokinetic interactions with leukemia therapy
-
Stavudine and zidovudine (AZT) are NOT allowed because of overlapping toxicity with protocol therapy
-
Patients must be able and willing to receive prophylaxis with daily aspirin, low molecular weight heparin, factor X inhibitors or warfarin if randomized to lenalidomide; patients must also be willing to receive pneumocystis jirovecii prophylaxis with sulfamethoxazole/trimethoprim, dapsone, atovaquone or inhaled pentamidine, in the event that they are randomized to TGR-1202; patients unable or unwilling to take any listed prophylaxis are NOT eligible
-
Patients must be able to discontinue CYP2C9 substrates with a narrow therapeutic index (e.g. warfarin, phenytoin), if randomized to TGR-1202; patients must discontinue such agents at least 1 week or 5 half-lives prior to beginning protocol therapy (whichever is longer)
-
No second prior malignancy is allowed except for adequately treated basal (or squamous cell) skin cancer, in situ cervical cancer or other cancer for which the patient has been disease free for three years
-
Patients must have a complete history and physical examination within 28 days prior to registration
-
Females of childbearing potential (FCBP) must have a negative serum or urine pregnancy test with a sensitivity of at least 25 mIU/mL within 10-14 days and again within 24 hours prior to starting cycle 1 of lenalidomide; further, they must either commit to complete abstinence (true abstinence is acceptable when this is in line with the preferred and usual lifestyle of the subject; periodic abstinence [e.g., calendar, ovulation, symptothermal or post ovulation methods] and withdrawal are not acceptable methods of contraception) from heterosexual intercourse or begin TWO acceptable methods of birth control: one highly effective method and one additional effective method AT THE SAME TIME, at least 28 days before starting lenalidomide; while taking lenalidomide, during dose interruptions, and for at least 28 days after the last dose of lenalidomide; FCBP must also agree to ongoing pregnancy testing; men must agree to use a latex condom during sexual contact with a FCBP, even if they have had a successful vasectomy; a FCBP is a female who: 1) has achieve menarche at some point;
- has not undergone a hysterectomy or bilateral oophorectomy; or 3) has not been naturally postmenopausal (amenorrhea following cancer therapy does not rule out childbearing potential) for at least 24 consecutive months (i.e., has had menses at any time in the preceding 24 consecutive months); all patients must be counseled by a trained counselor every 28 days about pregnancy precautions and risks of fetal exposure; NOTE: patients not randomized to receive lenalidomide will not be required to undergo serial pregnancy testing or lenalidomide counseling after registration
-
Patients must have lactate dehydrogenase (LDH) and beta-2-microglobulin collected within 28 days prior to registration
-
Patients must be informed of the investigational nature of this study and must sign and give written informed consent in accordance with institutional and federal guidelines
-
As a part of the Oncology Patient Enrollment Network (OPEN) registration process the treating institution's identity is provided in order to ensure that the current (within 365 days) date of institutional review board approval for this study has been entered in the system
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
---|---|---|---|---|---|
1 | Alaska Breast Care and Surgery LLC | Anchorage | Alaska | United States | 99508 |
2 | Alaska Oncology and Hematology LLC | Anchorage | Alaska | United States | 99508 |
3 | Alaska Women's Cancer Care | Anchorage | Alaska | United States | 99508 |
4 | Anchorage Oncology Centre | Anchorage | Alaska | United States | 99508 |
5 | Katmai Oncology Group | Anchorage | Alaska | United States | 99508 |
6 | Providence Alaska Medical Center | Anchorage | Alaska | United States | 99508 |
7 | Banner University Medical Center - Tucson | Tucson | Arizona | United States | 85719 |
8 | University of Arizona Cancer Center-North Campus | Tucson | Arizona | United States | 85719 |
9 | Kaiser Permanente-Anaheim | Anaheim | California | United States | 92806 |
10 | Kaiser Permanente-Deer Valley Medical Center | Antioch | California | United States | 94531 |
11 | PCR Oncology | Arroyo Grande | California | United States | 93420 |
12 | Sutter Auburn Faith Hospital | Auburn | California | United States | 95602 |
13 | Kaiser Permanente-Baldwin Park | Baldwin Park | California | United States | 91706 |
14 | Kaiser Permanente-Bellflower | Bellflower | California | United States | 90706 |
15 | Alta Bates Summit Medical Center-Herrick Campus | Berkeley | California | United States | 94704 |
16 | Providence Saint Joseph Medical Center/Disney Family Cancer Center | Burbank | California | United States | 91505 |
17 | City of Hope Comprehensive Cancer Center | Duarte | California | United States | 91010 |
18 | Kaiser Permanente Dublin | Dublin | California | United States | 94568 |
19 | Kaiser Permanente-Fontana | Fontana | California | United States | 92335 |
20 | Kaiser Permanente-Fremont | Fremont | California | United States | 94538 |
21 | Kaiser Permanente-Fresno | Fresno | California | United States | 93720 |
22 | Kaiser Permanente - Harbor City | Harbor City | California | United States | 90710 |
23 | Kaiser Permanente-Irvine | Irvine | California | United States | 92618 |
24 | Loma Linda University Medical Center | Loma Linda | California | United States | 92354 |
25 | Kaiser Permanente Los Angeles Medical Center | Los Angeles | California | United States | 90027 |
26 | Kaiser Permanente West Los Angeles | Los Angeles | California | United States | 90034 |
27 | Memorial Medical Center | Modesto | California | United States | 95355 |
28 | Kaiser Permanente-Modesto | Modesto | California | United States | 95356 |
29 | Palo Alto Medical Foundation-Camino Division | Mountain View | California | United States | 94040 |
30 | Palo Alto Medical Foundation-Gynecologic Oncology | Mountain View | California | United States | 94040 |
31 | Kaiser Permanente Oakland-Broadway | Oakland | California | United States | 94611 |
32 | Kaiser Permanente-Oakland | Oakland | California | United States | 94611 |
33 | Kaiser Permanente-Ontario | Ontario | California | United States | 91761 |
34 | Palo Alto Medical Foundation Health Care | Palo Alto | California | United States | 94301 |
35 | VA Palo Alto Health Care System | Palo Alto | California | United States | 94304 |
36 | Kaiser Permanente - Panorama City | Panorama City | California | United States | 91402 |
37 | Eisenhower Medical Center | Rancho Mirage | California | United States | 92270 |
38 | Kaiser Permanente-Richmond | Richmond | California | United States | 94801 |
39 | Kaiser Permanente-Roseville | Roseville | California | United States | 95661 |
40 | Kaiser Permanente Downtown Commons | Sacramento | California | United States | 95814 |
41 | Sutter Medical Center Sacramento | Sacramento | California | United States | 95816 |
42 | Kaiser Permanente-South Sacramento | Sacramento | California | United States | 95823 |
43 | Kaiser Permanente - Sacramento | Sacramento | California | United States | 95825 |
44 | Kaiser Permanente-San Diego Mission | San Diego | California | United States | 92108 |
45 | Kaiser Permanente-San Diego Zion | San Diego | California | United States | 92120 |
46 | California Pacific Medical Center-Pacific Campus | San Francisco | California | United States | 94115 |
47 | Kaiser Permanente-San Francisco | San Francisco | California | United States | 94115 |
48 | Kaiser Permanente-Santa Teresa-San Jose | San Jose | California | United States | 95119 |
49 | Kaiser Permanente San Leandro | San Leandro | California | United States | 94577 |
50 | Kaiser Permanente-San Marcos | San Marcos | California | United States | 92078 |
51 | Kaiser Permanente-San Rafael | San Rafael | California | United States | 94903 |
52 | Kaiser San Rafael-Gallinas | San Rafael | California | United States | 94903 |
53 | Kaiser Permanente Medical Center - Santa Clara | Santa Clara | California | United States | 95051 |
54 | Palo Alto Medical Foundation-Santa Cruz | Santa Cruz | California | United States | 95065 |
55 | Kaiser Permanente-Santa Rosa | Santa Rosa | California | United States | 95403 |
56 | Sutter Pacific Medical Foundation | Santa Rosa | California | United States | 95403 |
57 | Kaiser Permanente-South San Francisco | South San Francisco | California | United States | 94080 |
58 | Kaiser Permanente-Stockton | Stockton | California | United States | 95210 |
59 | Palo Alto Medical Foundation-Sunnyvale | Sunnyvale | California | United States | 94086 |
60 | Kaiser Permanente Medical Center-Vacaville | Vacaville | California | United States | 95688 |
61 | Kaiser Permanente-Vallejo | Vallejo | California | United States | 94589 |
62 | Kaiser Permanente-Walnut Creek | Walnut Creek | California | United States | 94596 |
63 | Kaiser Permanente-Woodland Hills | Woodland Hills | California | United States | 91367 |
64 | Rocky Mountain Cancer Centers-Aurora | Aurora | Colorado | United States | 80012 |
65 | The Medical Center of Aurora | Aurora | Colorado | United States | 80012 |
66 | Boulder Community Hospital | Boulder | Colorado | United States | 80301 |
67 | Rocky Mountain Cancer Centers-Boulder | Boulder | Colorado | United States | 80304 |
68 | Penrose-Saint Francis Healthcare | Colorado Springs | Colorado | United States | 80907 |
69 | Rocky Mountain Cancer Centers-Penrose | Colorado Springs | Colorado | United States | 80907 |
70 | Denver Health Medical Center | Denver | Colorado | United States | 80204 |
71 | Porter Adventist Hospital | Denver | Colorado | United States | 80210 |
72 | Colorado Blood Cancer Institute | Denver | Colorado | United States | 80218 |
73 | Presbyterian - Saint Lukes Medical Center - Health One | Denver | Colorado | United States | 80218 |
74 | Rocky Mountain Cancer Centers-Midtown | Denver | Colorado | United States | 80218 |
75 | SCL Health Saint Joseph Hospital | Denver | Colorado | United States | 80218 |
76 | Rocky Mountain Cancer Centers-Rose | Denver | Colorado | United States | 80220 |
77 | Rose Medical Center | Denver | Colorado | United States | 80220 |
78 | Mercy Medical Center | Durango | Colorado | United States | 81301 |
79 | Mountain Blue Cancer Care Center - Swedish | Englewood | Colorado | United States | 80113 |
80 | Swedish Medical Center | Englewood | Colorado | United States | 80113 |
81 | Mountain Blue Cancer Care Center | Golden | Colorado | United States | 80401 |
82 | Saint Mary's Hospital and Regional Medical Center | Grand Junction | Colorado | United States | 81501 |
83 | North Colorado Medical Center | Greeley | Colorado | United States | 80631 |
84 | Rocky Mountain Cancer Centers-Greenwood Village | Greenwood Village | Colorado | United States | 80111 |
85 | Rocky Mountain Cancer Centers-Lakewood | Lakewood | Colorado | United States | 80228 |
86 | Saint Anthony Hospital | Lakewood | Colorado | United States | 80228 |
87 | Rocky Mountain Cancer Centers-Littleton | Littleton | Colorado | United States | 80120 |
88 | Littleton Adventist Hospital | Littleton | Colorado | United States | 80122 |
89 | Rocky Mountain Cancer Centers-Sky Ridge | Lone Tree | Colorado | United States | 80124 |
90 | Sky Ridge Medical Center | Lone Tree | Colorado | United States | 80124 |
91 | Longmont United Hospital | Longmont | Colorado | United States | 80501 |
92 | Rocky Mountain Cancer Centers-Longmont | Longmont | Colorado | United States | 80501 |
93 | McKee Medical Center | Loveland | Colorado | United States | 80539 |
94 | Parker Adventist Hospital | Parker | Colorado | United States | 80138 |
95 | Rocky Mountain Cancer Centers-Parker | Parker | Colorado | United States | 80138 |
96 | Saint Mary Corwin Medical Center | Pueblo | Colorado | United States | 81004 |
97 | Rocky Mountain Cancer Centers-Thornton | Thornton | Colorado | United States | 80260 |
98 | SCL Health Lutheran Medical Center | Wheat Ridge | Colorado | United States | 80033 |
99 | Smilow Cancer Hospital Care Center at Saint Francis | Hartford | Connecticut | United States | 06105 |
100 | Smilow Cancer Center/Yale-New Haven Hospital | New Haven | Connecticut | United States | 06510 |
101 | Yale University | New Haven | Connecticut | United States | 06520 |
102 | Yale-New Haven Hospital North Haven Medical Center | North Haven | Connecticut | United States | 06473 |
103 | University of Florida Health Science Center - Gainesville | Gainesville | Florida | United States | 32610 |
104 | Baptist MD Anderson Cancer Center | Jacksonville | Florida | United States | 32207 |
105 | Emory University Hospital/Winship Cancer Institute | Atlanta | Georgia | United States | 30322 |
106 | Lewis Cancer and Research Pavilion at Saint Joseph's/Candler | Savannah | Georgia | United States | 31405 |
107 | Kaiser Permanente Moanalua Medical Center | Honolulu | Hawaii | United States | 96819 |
108 | Saint Alphonsus Cancer Care Center-Boise | Boise | Idaho | United States | 83706 |
109 | Saint Luke's Cancer Institute - Boise | Boise | Idaho | United States | 83712 |
110 | Saint Luke's Cancer Institute - Fruitland | Fruitland | Idaho | United States | 83619 |
111 | Saint Luke's Cancer Institute - Meridian | Meridian | Idaho | United States | 83642 |
112 | Saint Luke's Cancer Institute - Nampa | Nampa | Idaho | United States | 83686 |
113 | Kootenai Clinic Cancer Services - Post Falls | Post Falls | Idaho | United States | 83854 |
114 | Saint Luke's Cancer Institute - Twin Falls | Twin Falls | Idaho | United States | 83301 |
115 | Illinois CancerCare-Bloomington | Bloomington | Illinois | United States | 61704 |
116 | Illinois CancerCare-Canton | Canton | Illinois | United States | 61520 |
117 | Illinois CancerCare-Carthage | Carthage | Illinois | United States | 62321 |
118 | Northwestern University | Chicago | Illinois | United States | 60611 |
119 | Rush University Medical Center | Chicago | Illinois | United States | 60612 |
120 | University of Chicago Comprehensive Cancer Center | Chicago | Illinois | United States | 60637 |
121 | Carle on Vermilion | Danville | Illinois | United States | 61832 |
122 | Cancer Care Specialists of Illinois - Decatur | Decatur | Illinois | United States | 62526 |
123 | Decatur Memorial Hospital | Decatur | Illinois | United States | 62526 |
124 | Carle Physician Group-Effingham | Effingham | Illinois | United States | 62401 |
125 | Crossroads Cancer Center | Effingham | Illinois | United States | 62401 |
126 | Illinois CancerCare-Eureka | Eureka | Illinois | United States | 61530 |
127 | Illinois CancerCare-Galesburg | Galesburg | Illinois | United States | 61401 |
128 | Northwestern Medicine Cancer Center Delnor | Geneva | Illinois | United States | 60134 |
129 | Illinois CancerCare-Kewanee Clinic | Kewanee | Illinois | United States | 61443 |
130 | Northwestern Medicine Lake Forest Hospital | Lake Forest | Illinois | United States | 60045 |
131 | Illinois CancerCare-Macomb | Macomb | Illinois | United States | 61455 |
132 | Carle Physician Group-Mattoon/Charleston | Mattoon | Illinois | United States | 61938 |
133 | Loyola University Medical Center | Maywood | Illinois | United States | 60153 |
134 | Cancer Care Center of O'Fallon | O'Fallon | Illinois | United States | 62269 |
135 | Illinois CancerCare-Ottawa Clinic | Ottawa | Illinois | United States | 61350 |
136 | Illinois CancerCare-Pekin | Pekin | Illinois | United States | 61554 |
137 | Illinois CancerCare-Peoria | Peoria | Illinois | United States | 61615 |
138 | Illinois CancerCare-Peru | Peru | Illinois | United States | 61354 |
139 | Illinois CancerCare-Princeton | Princeton | Illinois | United States | 61356 |
140 | SwedishAmerican Regional Cancer Center/ACT | Rockford | Illinois | United States | 61114 |
141 | Southern Illinois University School of Medicine | Springfield | Illinois | United States | 62702 |
142 | Springfield Clinic | Springfield | Illinois | United States | 62702 |
143 | Memorial Medical Center | Springfield | Illinois | United States | 62781 |
144 | Carle Cancer Center | Urbana | Illinois | United States | 61801 |
145 | The Carle Foundation Hospital | Urbana | Illinois | United States | 61801 |
146 | Northwestern Medicine Cancer Center Warrenville | Warrenville | Illinois | United States | 60555 |
147 | Parkview Hospital Randallia | Fort Wayne | Indiana | United States | 46805 |
148 | Parkview Regional Medical Center | Fort Wayne | Indiana | United States | 46845 |
149 | Reid Health | Richmond | Indiana | United States | 47374 |
150 | Medical Oncology and Hematology Associates-West Des Moines | Clive | Iowa | United States | 50325 |
151 | Mercy Cancer Center-West Lakes | Clive | Iowa | United States | 50325 |
152 | Iowa Methodist Medical Center | Des Moines | Iowa | United States | 50309 |
153 | Medical Oncology and Hematology Associates-Des Moines | Des Moines | Iowa | United States | 50309 |
154 | Broadlawns Medical Center | Des Moines | Iowa | United States | 50314 |
155 | Medical Oncology and Hematology Associates-Laurel | Des Moines | Iowa | United States | 50314 |
156 | Mercy Medical Center - Des Moines | Des Moines | Iowa | United States | 50314 |
157 | Iowa Lutheran Hospital | Des Moines | Iowa | United States | 50316 |
158 | Trinity Regional Medical Center | Fort Dodge | Iowa | United States | 50501 |
159 | University of Iowa/Holden Comprehensive Cancer Center | Iowa City | Iowa | United States | 52242 |
160 | Siouxland Regional Cancer Center | Sioux City | Iowa | United States | 51101 |
161 | Methodist West Hospital | West Des Moines | Iowa | United States | 50266-7700 |
162 | Mercy Medical Center-West Lakes | West Des Moines | Iowa | United States | 50266 |
163 | Cancer Center of Kansas - Chanute | Chanute | Kansas | United States | 66720 |
164 | Cancer Center of Kansas - Dodge City | Dodge City | Kansas | United States | 67801 |
165 | Cancer Center of Kansas - El Dorado | El Dorado | Kansas | United States | 67042 |
166 | Central Care Cancer Center - Great Bend | Great Bend | Kansas | United States | 67530 |
167 | Cancer Center of Kansas-Independence | Independence | Kansas | United States | 67301 |
168 | Cancer Center of Kansas-Kingman | Kingman | Kansas | United States | 67068 |
169 | Lawrence Memorial Hospital | Lawrence | Kansas | United States | 66044 |
170 | Cancer Center of Kansas-Liberal | Liberal | Kansas | United States | 67905 |
171 | Cancer Center of Kansas-Manhattan | Manhattan | Kansas | United States | 66502 |
172 | Cancer Center of Kansas - McPherson | McPherson | Kansas | United States | 67460 |
173 | Cancer Center of Kansas - Newton | Newton | Kansas | United States | 67114 |
174 | Cancer Center of Kansas - Parsons | Parsons | Kansas | United States | 67357 |
175 | Cancer Center of Kansas - Pratt | Pratt | Kansas | United States | 67124 |
176 | Cancer Center of Kansas - Salina | Salina | Kansas | United States | 67401 |
177 | Cancer Center of Kansas - Wellington | Wellington | Kansas | United States | 67152 |
178 | Cancer Center of Kansas-Wichita Medical Arts Tower | Wichita | Kansas | United States | 67208 |
179 | Cancer Center of Kansas - Wichita | Wichita | Kansas | United States | 67214 |
180 | Wesley Medical Center | Wichita | Kansas | United States | 67214 |
181 | Cancer Center of Kansas - Winfield | Winfield | Kansas | United States | 67156 |
182 | Flaget Memorial Hospital | Bardstown | Kentucky | United States | 40004 |
183 | Jewish Hospital | Louisville | Kentucky | United States | 40202 |
184 | Saints Mary and Elizabeth Hospital | Louisville | Kentucky | United States | 40215 |
185 | UofL Health Medical Center Northeast | Louisville | Kentucky | United States | 40245 |
186 | Baton Rouge General Medical Center | Baton Rouge | Louisiana | United States | 70806 |
187 | Hematology/Oncology Clinic PLLC | Baton Rouge | Louisiana | United States | 70809 |
188 | Tulane University Health Sciences Center | New Orleans | Louisiana | United States | 70112 |
189 | Ochsner Medical Center Jefferson | New Orleans | Louisiana | United States | 70121 |
190 | Lahey Hospital and Medical Center | Burlington | Massachusetts | United States | 01805 |
191 | Saint Joseph Mercy Hospital | Ann Arbor | Michigan | United States | 48106 |
192 | University of Michigan Comprehensive Cancer Center | Ann Arbor | Michigan | United States | 48109 |
193 | Bronson Battle Creek | Battle Creek | Michigan | United States | 49017 |
194 | Saint Joseph Mercy Brighton | Brighton | Michigan | United States | 48114 |
195 | Trinity Health IHA Medical Group Hematology Oncology - Brighton | Brighton | Michigan | United States | 48114 |
196 | Henry Ford Cancer Institute-Downriver | Brownstown | Michigan | United States | 48183 |
197 | Saint Joseph Mercy Canton | Canton | Michigan | United States | 48188 |
198 | Trinity Health IHA Medical Group Hematology Oncology - Canton | Canton | Michigan | United States | 48188 |
199 | Saint Joseph Mercy Chelsea | Chelsea | Michigan | United States | 48118 |
200 | Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital | Chelsea | Michigan | United States | 48118 |
201 | Henry Ford Macomb Hospital-Clinton Township | Clinton Township | Michigan | United States | 48038 |
202 | Beaumont Hospital - Dearborn | Dearborn | Michigan | United States | 48124 |
203 | Henry Ford Medical Center-Fairlane | Dearborn | Michigan | United States | 48126 |
204 | Henry Ford Hospital | Detroit | Michigan | United States | 48202 |
205 | Ascension Saint John Hospital | Detroit | Michigan | United States | 48236 |
206 | Great Lakes Cancer Management Specialists-Doctors Park | East China Township | Michigan | United States | 48054 |
207 | Genesys Hurley Cancer Institute | Flint | Michigan | United States | 48503 |
208 | Helen DeVos Children's Hospital at Spectrum Health | Grand Rapids | Michigan | United States | 49503 |
209 | Mercy Health Saint Mary's | Grand Rapids | Michigan | United States | 49503 |
210 | Spectrum Health at Butterworth Campus | Grand Rapids | Michigan | United States | 49503 |
211 | Academic Hematology Oncology Specialists | Grosse Pointe Woods | Michigan | United States | 48236 |
212 | Great Lakes Cancer Management Specialists-Van Elslander Cancer Center | Grosse Pointe Woods | Michigan | United States | 48236 |
213 | Michigan Breast Specialists-Grosse Pointe Woods | Grosse Pointe Woods | Michigan | United States | 48236 |
214 | Allegiance Health | Jackson | Michigan | United States | 49201 |
215 | West Michigan Cancer Center | Kalamazoo | Michigan | United States | 49007 |
216 | Sparrow Hospital | Lansing | Michigan | United States | 48912 |
217 | Trinity Health Saint Mary Mercy Livonia Hospital | Livonia | Michigan | United States | 48154 |
218 | Great Lakes Cancer Management Specialists-Macomb Medical Campus | Macomb | Michigan | United States | 48044 |
219 | Michigan Breast Specialists-Macomb Township | Macomb | Michigan | United States | 48044 |
220 | Mercy Health Mercy Campus | Muskegon | Michigan | United States | 49444 |
221 | Henry Ford Medical Center-Columbus | Novi | Michigan | United States | 48377 |
222 | Saint Joseph Mercy Oakland | Pontiac | Michigan | United States | 48341 |
223 | Lake Huron Medical Center | Port Huron | Michigan | United States | 48060 |
224 | Spectrum Health Reed City Hospital | Reed City | Michigan | United States | 49677 |
225 | Great Lakes Cancer Management Specialists-Rochester Hills | Rochester Hills | Michigan | United States | 48309 |
226 | Ascension Saint Mary's Hospital | Saginaw | Michigan | United States | 48601 |
227 | Lakeland Medical Center Saint Joseph | Saint Joseph | Michigan | United States | 49085 |
228 | Marie Yeager Cancer Center | Saint Joseph | Michigan | United States | 49085 |
229 | Bhadresh Nayak MD PC-Sterling Heights | Sterling Heights | Michigan | United States | 48312 |
230 | Munson Medical Center | Traverse City | Michigan | United States | 49684 |
231 | Advanced Breast Care Center PLLC | Warren | Michigan | United States | 48088 |
232 | Great Lakes Cancer Management Specialists-Macomb Professional Building | Warren | Michigan | United States | 48093 |
233 | Macomb Hematology Oncology PC | Warren | Michigan | United States | 48093 |
234 | Michigan Breast Specialists-Warren | Warren | Michigan | United States | 48093 |
235 | Saint John Macomb-Oakland Hospital | Warren | Michigan | United States | 48093 |
236 | Henry Ford West Bloomfield Hospital | West Bloomfield | Michigan | United States | 48322 |
237 | Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus | Ypsilanti | Michigan | United States | 48197 |
238 | Sanford Joe Lueken Cancer Center | Bemidji | Minnesota | United States | 56601 |
239 | Fairview Ridges Hospital | Burnsville | Minnesota | United States | 55337 |
240 | Mercy Hospital | Coon Rapids | Minnesota | United States | 55433 |
241 | Essentia Health - Deer River Clinic | Deer River | Minnesota | United States | 56636 |
242 | Essentia Health Cancer Center | Duluth | Minnesota | United States | 55805 |
243 | Essentia Health Saint Mary's Medical Center | Duluth | Minnesota | United States | 55805 |
244 | Miller-Dwan Hospital | Duluth | Minnesota | United States | 55805 |
245 | Fairview Southdale Hospital | Edina | Minnesota | United States | 55435 |
246 | Lake Region Healthcare Corporation-Cancer Care | Fergus Falls | Minnesota | United States | 56537 |
247 | Unity Hospital | Fridley | Minnesota | United States | 55432 |
248 | Essentia Health Hibbing Clinic | Hibbing | Minnesota | United States | 55746 |
249 | Minnesota Oncology Hematology PA-Maplewood | Maplewood | Minnesota | United States | 55109 |
250 | Saint John's Hospital - Healtheast | Maplewood | Minnesota | United States | 55109 |
251 | Abbott-Northwestern Hospital | Minneapolis | Minnesota | United States | 55407 |
252 | Hennepin County Medical Center | Minneapolis | Minnesota | United States | 55415 |
253 | Health Partners Inc | Minneapolis | Minnesota | United States | 55454 |
254 | North Memorial Medical Health Center | Robbinsdale | Minnesota | United States | 55422 |
255 | Mayo Clinic in Rochester | Rochester | Minnesota | United States | 55905 |
256 | Coborn Cancer Center at Saint Cloud Hospital | Saint Cloud | Minnesota | United States | 56303 |
257 | Park Nicollet Clinic - Saint Louis Park | Saint Louis Park | Minnesota | United States | 55416 |
258 | Regions Hospital | Saint Paul | Minnesota | United States | 55101 |
259 | United Hospital | Saint Paul | Minnesota | United States | 55102 |
260 | Essentia Health Sandstone | Sandstone | Minnesota | United States | 55072 |
261 | Saint Francis Regional Medical Center | Shakopee | Minnesota | United States | 55379 |
262 | Lakeview Hospital | Stillwater | Minnesota | United States | 55082 |
263 | Essentia Health Virginia Clinic | Virginia | Minnesota | United States | 55792 |
264 | Ridgeview Medical Center | Waconia | Minnesota | United States | 55387 |
265 | Rice Memorial Hospital | Willmar | Minnesota | United States | 56201 |
266 | Minnesota Oncology Hematology PA-Woodbury | Woodbury | Minnesota | United States | 55125 |
267 | Central Care Cancer Center - Bolivar | Bolivar | Missouri | United States | 65613 |
268 | Parkland Health Center-Bonne Terre | Bonne Terre | Missouri | United States | 63628 |
269 | Saint Francis Medical Center | Cape Girardeau | Missouri | United States | 63703 |
270 | Southeast Cancer Center | Cape Girardeau | Missouri | United States | 63703 |
271 | Siteman Cancer Center at West County Hospital | Creve Coeur | Missouri | United States | 63141 |
272 | Capital Region Southwest Campus | Jefferson City | Missouri | United States | 65109 |
273 | Saint Luke's Hospital of Kansas City | Kansas City | Missouri | United States | 64111 |
274 | Kansas City Veterans Affairs Medical Center | Kansas City | Missouri | United States | 64128 |
275 | Delbert Day Cancer Institute at PCRMC | Rolla | Missouri | United States | 65401 |
276 | Mercy Clinic-Rolla-Cancer and Hematology | Rolla | Missouri | United States | 65401 |
277 | Saint Louis Cancer and Breast Institute-South City | Saint Louis | Missouri | United States | 63109 |
278 | Washington University School of Medicine | Saint Louis | Missouri | United States | 63110 |
279 | Mercy Hospital South | Saint Louis | Missouri | United States | 63128 |
280 | Siteman Cancer Center-South County | Saint Louis | Missouri | United States | 63129 |
281 | Missouri Baptist Medical Center | Saint Louis | Missouri | United States | 63131 |
282 | Siteman Cancer Center at Christian Hospital | Saint Louis | Missouri | United States | 63136 |
283 | Mercy Hospital Saint Louis | Saint Louis | Missouri | United States | 63141 |
284 | Siteman Cancer Center at Saint Peters Hospital | Saint Peters | Missouri | United States | 63376 |
285 | Sainte Genevieve County Memorial Hospital | Sainte Genevieve | Missouri | United States | 63670 |
286 | Mercy Hospital Springfield | Springfield | Missouri | United States | 65804 |
287 | CoxHealth South Hospital | Springfield | Missouri | United States | 65807 |
288 | Missouri Baptist Sullivan Hospital | Sullivan | Missouri | United States | 63080 |
289 | Missouri Baptist Outpatient Center-Sunset Hills | Sunset Hills | Missouri | United States | 63127 |
290 | Billings Clinic Cancer Center | Billings | Montana | United States | 59101 |
291 | Bozeman Deaconess Hospital | Bozeman | Montana | United States | 59715 |
292 | Saint James Community Hospital and Cancer Treatment Center | Butte | Montana | United States | 59701 |
293 | Benefis Healthcare- Sletten Cancer Institute | Great Falls | Montana | United States | 59405 |
294 | Kalispell Regional Medical Center | Kalispell | Montana | United States | 59901 |
295 | Saint Patrick Hospital - Community Hospital | Missoula | Montana | United States | 59802 |
296 | Community Medical Hospital | Missoula | Montana | United States | 59804 |
297 | Nebraska Medicine-Bellevue | Bellevue | Nebraska | United States | 68123 |
298 | CHI Health Saint Francis | Grand Island | Nebraska | United States | 68803 |
299 | CHI Health Good Samaritan | Kearney | Nebraska | United States | 68847 |
300 | Nebraska Medicine-Village Pointe | Omaha | Nebraska | United States | 68118 |
301 | University of Nebraska Medical Center | Omaha | Nebraska | United States | 68198 |
302 | Carson Tahoe Regional Medical Center | Carson City | Nevada | United States | 89703 |
303 | Cancer and Blood Specialists-Henderson | Henderson | Nevada | United States | 89052 |
304 | Comprehensive Cancer Centers of Nevada - Henderson | Henderson | Nevada | United States | 89052 |
305 | Las Vegas Cancer Center-Henderson | Henderson | Nevada | United States | 89052 |
306 | Comprehensive Cancer Centers of Nevada-Southeast Henderson | Henderson | Nevada | United States | 89074 |
307 | GenesisCare USA - Henderson | Henderson | Nevada | United States | 89074 |
308 | University Medical Center of Southern Nevada | Las Vegas | Nevada | United States | 89102 |
309 | Cancer and Blood Specialists-Shadow | Las Vegas | Nevada | United States | 89106 |
310 | Radiation Oncology Centers of Nevada Central | Las Vegas | Nevada | United States | 89106 |
311 | GenesisCare USA - Las Vegas | Las Vegas | Nevada | United States | 89109 |
312 | HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway | Las Vegas | Nevada | United States | 89109 |
313 | Sunrise Hospital and Medical Center | Las Vegas | Nevada | United States | 89109 |
314 | HealthCare Partners Medical Group Oncology/Hematology-San Martin | Las Vegas | Nevada | United States | 89113 |
315 | Radiation Oncology Centers of Nevada Southeast | Las Vegas | Nevada | United States | 89119 |
316 | Ann M Wierman MD LTD | Las Vegas | Nevada | United States | 89128 |
317 | Comprehensive Cancer Centers of Nevada - Northwest | Las Vegas | Nevada | United States | 89128 |
318 | GenesisCare USA - Vegas Tenaya | Las Vegas | Nevada | United States | 89128 |
319 | HealthCare Partners Medical Group Oncology/Hematology-Tenaya | Las Vegas | Nevada | United States | 89128 |
320 | Alliance for Childhood Diseases/Cure 4 the Kids Foundation | Las Vegas | Nevada | United States | 89135 |
321 | Comprehensive Cancer Centers of Nevada-Summerlin | Las Vegas | Nevada | United States | 89144 |
322 | Summerlin Hospital Medical Center | Las Vegas | Nevada | United States | 89144 |
323 | Las Vegas Cancer Center-Medical Center | Las Vegas | Nevada | United States | 89148-2405 |
324 | Comprehensive Cancer Centers of Nevada | Las Vegas | Nevada | United States | 89148 |
325 | GenesisCare USA - Fort Apache | Las Vegas | Nevada | United States | 89148 |
326 | OptumCare Cancer Care at Fort Apache | Las Vegas | Nevada | United States | 89148 |
327 | HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills | Las Vegas | Nevada | United States | 89149 |
328 | Comprehensive Cancer Centers of Nevada - Central Valley | Las Vegas | Nevada | United States | 89169 |
329 | University Cancer Center | Las Vegas | Nevada | United States | 89169 |
330 | Renown Regional Medical Center | Reno | Nevada | United States | 89502 |
331 | Saint Mary's Regional Medical Center | Reno | Nevada | United States | 89503 |
332 | Dartmouth Hitchcock Medical Center | Lebanon | New Hampshire | United States | 03756 |
333 | University of New Mexico Cancer Center | Albuquerque | New Mexico | United States | 87102 |
334 | Roswell Park Cancer Institute | Buffalo | New York | United States | 14263 |
335 | Northwell Health/Center for Advanced Medicine | Lake Success | New York | United States | 11042 |
336 | North Shore University Hospital | Manhasset | New York | United States | 11030 |
337 | Long Island Jewish Medical Center | New Hyde Park | New York | United States | 11040 |
338 | NYP/Weill Cornell Medical Center | New York | New York | United States | 10065 |
339 | University of Rochester | Rochester | New York | United States | 14642 |
340 | Carolinas Medical Center/Levine Cancer Institute | Charlotte | North Carolina | United States | 28203 |
341 | Southeastern Medical Oncology Center-Clinton | Clinton | North Carolina | United States | 28328 |
342 | Southeastern Medical Oncology Center-Goldsboro | Goldsboro | North Carolina | United States | 27534 |
343 | Wayne Memorial Hospital | Goldsboro | North Carolina | United States | 27534 |
344 | Margaret R Pardee Memorial Hospital | Hendersonville | North Carolina | United States | 28791 |
345 | Southeastern Medical Oncology Center-Jacksonville | Jacksonville | North Carolina | United States | 28546 |
346 | Sanford Bismarck Medical Center | Bismarck | North Dakota | United States | 58501 |
347 | Sanford Broadway Medical Center | Fargo | North Dakota | United States | 58122 |
348 | Sanford Roger Maris Cancer Center | Fargo | North Dakota | United States | 58122 |
349 | Good Samaritan Hospital - Cincinnati | Cincinnati | Ohio | United States | 45220 |
350 | TriHealth Cancer Institute-Westside | Cincinnati | Ohio | United States | 45247 |
351 | TriHealth Cancer Institute-Anderson | Cincinnati | Ohio | United States | 45255 |
352 | MetroHealth Medical Center | Cleveland | Ohio | United States | 44109 |
353 | Ohio State University Comprehensive Cancer Center | Columbus | Ohio | United States | 43210 |
354 | Mount Carmel East Hospital | Columbus | Ohio | United States | 43213 |
355 | Columbus Oncology and Hematology Associates Inc | Columbus | Ohio | United States | 43214 |
356 | Riverside Methodist Hospital | Columbus | Ohio | United States | 43214 |
357 | The Mark H Zangmeister Center | Columbus | Ohio | United States | 43219 |
358 | Mount Carmel Health Center West | Columbus | Ohio | United States | 43222 |
359 | Good Samaritan Hospital - Dayton | Dayton | Ohio | United States | 45406 |
360 | Miami Valley Hospital | Dayton | Ohio | United States | 45409 |
361 | Miami Valley Hospital North | Dayton | Ohio | United States | 45415 |
362 | Blanchard Valley Hospital | Findlay | Ohio | United States | 45840 |
363 | Saint Rita's Medical Center | Lima | Ohio | United States | 45801 |
364 | Marietta Memorial Hospital | Marietta | Ohio | United States | 45750 |
365 | Toledo Clinic Cancer Centers-Maumee | Maumee | Ohio | United States | 43537 |
366 | Licking Memorial Hospital | Newark | Ohio | United States | 43055 |
367 | Springfield Regional Cancer Center | Springfield | Ohio | United States | 45504 |
368 | Springfield Regional Medical Center | Springfield | Ohio | United States | 45505 |
369 | Toledo Clinic Cancer Centers-Toledo | Toledo | Ohio | United States | 43623 |
370 | Saint Ann's Hospital | Westerville | Ohio | United States | 43081 |
371 | University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | United States | 73104 |
372 | Clackamas Radiation Oncology Center | Clackamas | Oregon | United States | 97015 |
373 | Providence Cancer Institute Clackamas Clinic | Clackamas | Oregon | United States | 97015 |
374 | Bay Area Hospital | Coos Bay | Oregon | United States | 97420 |
375 | Providence Newberg Medical Center | Newberg | Oregon | United States | 97132 |
376 | Providence Portland Medical Center | Portland | Oregon | United States | 97213 |
377 | Providence Saint Vincent Medical Center | Portland | Oregon | United States | 97225 |
378 | Lehigh Valley Hospital-Cedar Crest | Allentown | Pennsylvania | United States | 18103 |
379 | Bryn Mawr Hospital | Bryn Mawr | Pennsylvania | United States | 19010 |
380 | Main Line Health Center-Collegeville | Collegeville | Pennsylvania | United States | 19426 |
381 | Geisinger Medical Center | Danville | Pennsylvania | United States | 17822 |
382 | Main Line Health Center-Exton | Exton | Pennsylvania | United States | 19341 |
383 | Geisinger Medical Center-Cancer Center Hazleton | Hazleton | Pennsylvania | United States | 18201 |
384 | Geisinger Medical Oncology-Lewisburg | Lewisburg | Pennsylvania | United States | 17837 |
385 | Riddle Memorial Hospital | Media | Pennsylvania | United States | 19063 |
386 | Paoli Memorial Hospital | Paoli | Pennsylvania | United States | 19301 |
387 | Geisinger Cancer Services-Pottsville | Pottsville | Pennsylvania | United States | 17901 |
388 | Geisinger Medical Oncology-Selinsgrove | Selinsgrove | Pennsylvania | United States | 17870 |
389 | Reading Hospital | West Reading | Pennsylvania | United States | 19611 |
390 | Geisinger Wyoming Valley/Henry Cancer Center | Wilkes-Barre | Pennsylvania | United States | 18711 |
391 | Lankenau Medical Center | Wynnewood | Pennsylvania | United States | 19096 |
392 | Medical University of South Carolina | Charleston | South Carolina | United States | 29425 |
393 | Saint Francis Hospital | Greenville | South Carolina | United States | 29601 |
394 | Saint Francis Cancer Center | Greenville | South Carolina | United States | 29607 |
395 | Self Regional Healthcare | Greenwood | South Carolina | United States | 29646 |
396 | Spartanburg Medical Center | Spartanburg | South Carolina | United States | 29303 |
397 | Sanford Cancer Center Oncology Clinic | Sioux Falls | South Dakota | United States | 57104 |
398 | Sanford USD Medical Center - Sioux Falls | Sioux Falls | South Dakota | United States | 57117-5134 |
399 | M D Anderson Cancer Center | Houston | Texas | United States | 77030 |
400 | Huntsman Cancer Institute/University of Utah | Salt Lake City | Utah | United States | 84112 |
401 | Swedish Cancer Institute-Edmonds | Edmonds | Washington | United States | 98026 |
402 | PeaceHealth Saint John Medical Center | Longview | Washington | United States | 98632 |
403 | MultiCare Good Samaritan Hospital | Puyallup | Washington | United States | 98372 |
404 | Swedish Medical Center-Ballard Campus | Seattle | Washington | United States | 98107 |
405 | Fred Hutchinson Cancer Research Center | Seattle | Washington | United States | 98109 |
406 | Seattle Cancer Care Alliance | Seattle | Washington | United States | 98109 |
407 | Swedish Medical Center-First Hill | Seattle | Washington | United States | 98122-4307 |
408 | PeaceHealth Southwest Medical Center | Vancouver | Washington | United States | 98664 |
409 | West Virginia University Charleston Division | Charleston | West Virginia | United States | 25304 |
410 | Duluth Clinic Ashland | Ashland | Wisconsin | United States | 54806 |
411 | Northwest Wisconsin Cancer Center | Ashland | Wisconsin | United States | 54806 |
412 | Marshfield Clinic-Chippewa Center | Chippewa Falls | Wisconsin | United States | 54729 |
413 | Gundersen Lutheran Medical Center | La Crosse | Wisconsin | United States | 54601 |
414 | Marshfield Clinic - Ladysmith Center | Ladysmith | Wisconsin | United States | 54848 |
415 | University of Wisconsin Carbone Cancer Center | Madison | Wisconsin | United States | 53792 |
416 | Marshfield Medical Center-Marshfield | Marshfield | Wisconsin | United States | 54449 |
417 | Medical College of Wisconsin | Milwaukee | Wisconsin | United States | 53226 |
418 | Marshfield Clinic-Minocqua Center | Minocqua | Wisconsin | United States | 54548 |
419 | Cancer Center of Western Wisconsin | New Richmond | Wisconsin | United States | 54017 |
420 | Marshfield Medical Center-Rice Lake | Rice Lake | Wisconsin | United States | 54868 |
421 | Marshfield Clinic-Wausau Center | Wausau | Wisconsin | United States | 54401 |
422 | Marshfield Medical Center - Weston | Weston | Wisconsin | United States | 54476 |
423 | Marshfield Clinic - Wisconsin Rapids Center | Wisconsin Rapids | Wisconsin | United States | 54494 |
Sponsors and Collaborators
- National Cancer Institute (NCI)
Investigators
- Principal Investigator: Paul M Barr, Southwest Oncology Group
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- NCI-2017-00009
- NCI-2017-00009
- S1608
- S1608
- U10CA180888