EHPAFAVE: Study of Hemostasis During the Atrial Fibrillation Ablation Procedure
Study Details
Study Description
Brief Summary
Anticoagulation monitoring is done by monitoring the ACT (Activated Clotting Time) with an objective greater than 300 s. Until now, treatment with direct oral anticoagulant (for the prevention of thromboembolic events of atrial fibrillation) was interrupted a few days before the procedure in order to limit the risk of per-procedural bleeding. However, 3 recent randomized studies concerning the 3 DOACs available suggest that treatment should not be interrupted during the entire operative period. The operation therefore takes place under double anticoagulation with a direct oral anticoagulant and unfractionated heparin. Under these conditions, ACT monitoring can no longer be considered a reliable means of measuring the level of anticoagulation. It was therefore necessary to explore the hemostasis of these patients in a broad way in order to avoid any risk of overdose of UFH (Unfractionated Heparin) during the procedure.
Condition or Disease | Intervention/Treatment | Phase |
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Study Design
Outcome Measures
Primary Outcome Measures
- Study of hemorrhagic and thrombotic complications and correlation with the various laboratory tests [Files analysed retrospectively from January 01, 2019 to December 31, 2019 will be examined]]
Eligibility Criteria
Criteria
Inclusion Criteria:
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Patients over 18 years-old
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with an atrial fibrillation
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Operated for an atrial fibrillation procedure in the University hospital of Strasbourg
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Without interruption of the direct oral anticoagulant
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For whom extended biological assessment has been made in routine practice
Exclusion Criteria:
- Patients who refused the use of their data for this study
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
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1 | Service d'Anesthésie et Réanimation chirurgicale - Hôpitaux Universitaires de Strasbourg | Strasbourg | France | 67091 |
Sponsors and Collaborators
- University Hospital, Strasbourg, France
Investigators
- Principal Investigator: Charles-Ambroise TACQUARD, MD, Service d'Anesthésie et Réanimation chirurgicale - Hôpitaux Universitaires de Strasbourg
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- 7717