Universal HIV Screening and Targeted HCV Screening in Emergency Department
Study Details
Study Description
Brief Summary
Cross-sectional study of patients consulting in the emergency room of the Centre hospitalier de l'Université de Montréal (CHUM), to assess the implementation of an "opt-out" screening program for HIV and HCV and prospective follow-up for 3 months of positive cases.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
N/A |
Detailed Description
The purpose of this study is to evaluate the feasibility of routine HIV and HCV screening using an "opt-out" approach at the emergency room of the CHUM and to determine the rate of new positive HIV and HCV cases. A sub-analysis will focus more specifically on HCV in the Quebec equivalent of "baby boomers" (1945-1975) since this is the group that was targeted in the United States. The second phase of this study will evaluate the effectiveness of the linkage to the healthcare system for people diagnosed with HIV or HCV and how fast these people are taken care of and put on treatment.
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Experimental: Patients consulting in the emergency room Patients consulting in the emergency room. |
Diagnostic Test: HIV and HCV screening
HIV test: ARCHITECT HIV Ag/Ab Combo, Abbott HCV test: ARCHITECT Anti-HCV, Abbott
|
Outcome Measures
Primary Outcome Measures
- Prevalence [4 months]
Prevalence of HIV and HCV among patients who consult at the ER of the CHUM (overall and undiagnosed cases)
Secondary Outcome Measures
- Prevalence among baby-boomers [4 months]
Determine the prevalence of new and pre-existing cases of HCV among "baby boomers" (1945 - 1975 years)
- Opt-out [4 months]
Determine the proportion of patients that opted-out of the routine screening for HIV and HCV at the ER
- Initial workup [1 year]
Among patients with a newly positive HIV or HCV test in the ER, determine the proportion of those who attended a first workup appointment at 1 month
- Cascade of care [1 year]
Determine the proportion that completed certain steps of the HIV and HCV care cascades at 1 or 3 months, ie confirmation of diagnosis (HIV and HCV: 1 month), liver fibrosis assessment (HCV: 3 months), and treatment initiation (HIV: 1 month and HCV: 3 months)
Eligibility Criteria
Criteria
Inclusion Criteria:
- Individuals attending the emergency room of the Centre hospitalier de l'Université de Montréal
Exclusion Criteria:
- Individuals unable to opt-out due to their psychological or physical condition
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Centre Hospitalier de l'Université de Montréal | Montréal | Quebec | Canada | H2X 3E4 |
Sponsors and Collaborators
- Centre hospitalier de l'Université de Montréal (CHUM)
- Ministere de la Sante et des Services Sociaux
- Gilead Sciences
- Merck Sharp & Dohme LLC
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- 17.300