How Astigmatism Influences Corneal Biomechanics and Intraocular Pressure

Sponsor

Medical University of Lodz (Other)

Overall Status

Completed

CT.gov ID

NCT03162471

Collaborator

(none)

Enrollment

139

Actual Duration (Months)

Study Details

Study Description

Brief Summary

The aim of the study was to identify whether preoperative corneal astigmatism can influence corneal biomechanics and the assessment of intraocular pressure (IOP) following micro-incision phacoemulsification.

Condition or Disease	Intervention/Treatment	Phase
Corneal Astigmatism Intraocular Pressure Cataract Senile	Diagnostic Test: non-contact measurement of intraocular pressure

Study Design

Study Type:

Observational

Actual Enrollment :

39 participants

Observational Model:

Other

Time Perspective:

Prospective

Official Title:

Impact of Preoperative Astigmatism on Corneal Biomechanics and Accurate Intraocular Pressure Measurement After Micro-incision Phacoemulsification

Actual Study Start Date :

May 1, 2005

Actual Primary Completion Date :

Dec 1, 2016

Actual Study Completion Date :

Dec 1, 2016

Outcome Measures

Primary Outcome Measures

change of corneal compensated IOP (IOPcc) [Parameter measured preoperatively and one day, one week, one month postoperatively]
Intraocular pressure and corneal biomechanical properties were measured using an Ocular Response Analyzer.

Secondary Outcome Measures

change of corneal hysteresis (CH) [Parameter measured preoperatively and one day, one week, one month postoperatively]
Intraocular pressure and corneal biomechanical properties were measured using an Ocular Response Analyzer.
change of corneal resistance factor (CRF) [Parameter measured preoperatively and one day, one week, one month postoperatively]
Intraocular pressure and corneal biomechanical properties were measured using an Ocular Response Analyzer.
change of Goldman-correlated IOP (IOPg) [Parameter measured preoperatively and one day, one week, one month postoperatively]
Intraocular pressure and corneal biomechanical properties were measured using an Ocular Response Analyzer.
change of waveform score (WS) [Parameter measured preoperatively and one day, one week, one month postoperatively]
Intraocular pressure and corneal biomechanical properties were measured using an Ocular Response Analyzer.

Eligibility Criteria

Criteria

Ages Eligible for Study:

52 Years to 90 Years

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria:

diagnosis and qualification for cataract surgery, corneal astigmatism of equal to or less than 2.25 Dcyl

Exclusion Criteria:

corneal astigmatism higher than 2.25 Dcyl, history of any other corneal disease (infection, trauma, ulceration, autoimmune inflammation, Fuchs Dystrophy, keratoconus, corneal scars, preoperative insufficiency of corneal endothelium), glaucoma and chronic use of non-glaucoma eye drops, blepharitis, dry eye, use of contact lenses diabetes or a history of corneal refractive surgery