Gabapentin Pretreatment for Staged Bilateral Cataract Operations
To evaluate the effect of oral gabapentin premedication on hyperalgesia in elderly patients undergoing staged bilateral cataract operations under monitored anesthesia care
|Condition or Disease||Intervention/Treatment||Phase|
It has been reported that patients with bilateral cataract complained more pain and discomfort during the second consecutive eye surgery compared to the first eye surgery.
Gabapentin is an anticonvulsant drug, which has been extended the use to perioperative analgesia, and anxiolysis.
Therefore, the investigators conducted this randomized, controlled study to evaluate the effects of gabapentin premedication on patients' subjective sensations, including intraoperative anxiety, perceptions of pain, and light sensitivity, in the second cataract operations.
Arms and Interventions
Gabapentin premedication group
Patients receive gabapentin 100mg orally for 3 times a day during the period of first and second cataract operations
|No Intervention: No medication
Primary Outcome Measures
- Pain perception [during the operation]
intraoperative pain perception evaluated by VAS in first and second cataract surgery
patients aged over 60 years, who undergoing staged bilateral cataract operations under monitored anesthesia care
ASA physical status of I, II, and III
undergoing other eye operations together besides cataract operation
patients with creatinin clearance lower than 30ml/min
patients with CNS inhibitors medication
patients with previous gabapentin medication
Contacts and Locations
|1||Seoul National University Hospital||Seoul||Korea, Republic of|
Sponsors and Collaborators
- Seoul National University Hospital
- Study Chair: Jeong-Hwa Seo, MD, Seoul National University Hospital
Study Documents (Full-Text)None provided.