Effects of WB-EMS and High Protein Diet in IBD Patients
Study Details
Study Description
Brief Summary
Patients with inflammatory bowel disease (IBD) often suffer from muscle weakness and a low bone mineral density as a consequence of systemic Inflammation and disease treatment limiting Quality of life in a considerable way. Exercise interventions to build up muscle mass and increasing physical function are promising Tools to improve the whole muscular Status of those patients. However, in the acute Phase of IBDs conventional Training methods may be too strenous, also because patients are suffering from acute gastrointestinal symptoms and feel fatigued. Due to those symptoms, patients present low Food intake and great loss of nutrients and energy especially by diarrhea. Individualized nutritional Support may be helpful to avoid malnutrition. The aim of this pilot study is to investigate the effect of a combined exercise and Nutrition Intervention using the gentle Training method of whole-body electromyostimulation (WB-EMS) combined with a individual high Protein nutritional Support on muscle mass, Body composition, physical function, Quality of life and gastrointestinal symptoms in outpatients with IBD.
Condition or Disease | Intervention/Treatment | Phase |
---|---|---|
|
N/A |
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
---|---|
No Intervention: Control group usual care treatment |
|
Experimental: Nutrition high-protein nutrition therapy |
Other: Nutritional support
dietary monitoring by dietary records; nutritional counselling by dietician, dietary advices: 1.5 g/kg bodyweight/day
|
Experimental: EMS+Nutrition WB-EMS Training (2x/week á 20 min) + high-protein nutrition therapy |
Other: WB-EMS
WB-EMS training is performed 2x/week for 12 weeks; Stimulation protocol: Frequency of 85 Hz, pulse duration of 0.35 ms, stimulation period of 6 sec, resting period of 4 sec; supervised by certified training instructors/physiotherapists participants perform simple exercises during the stimulation period following a video tutorial
Other: Nutritional support
dietary monitoring by dietary records; nutritional counselling by dietician, dietary advices: 1.5 g/kg bodyweight/day
|
Outcome Measures
Primary Outcome Measures
- Skeletal muscle mass [12 weeks]
assessed by bioelectrical impedance analysis in kg
Secondary Outcome Measures
- Body composition [12 weeks]
assessed by bioelectrical impedance analysis in kg or %
- Physical function - isometric muscle strength [12 weeks]
isometric hand grip strength assessed by hand dynamometer
- Physical function - Endurance [12 weeks]
Six-minute-walk test (walking distance in m)
- Physical function - lower limb strength [12 weeks]
isometric lower limb strength assessed by isometric force plates in N
- Quality of Life [12 weeks]
IBDQ-D
- Physical activity [12 weeks]
IPAQ
- Disease activity (Crohn's disease) [12 weeks]
Harvey Bradshaw Index
- Disease activity (ulcerative colitis) [12 weeks]
Mayo Score
- Inflammation status [12 weeks]
C-reactive protein (CRP)
Eligibility Criteria
Criteria
Inclusion Criteria:
-
outpatients with inflammatory bowel disease (Crohn's disease, ulcerative Colitis)
-
adults (18 years and older)
Exclusion Criteria:
-
simultaneous participation in other nutritional or exercise intervention Trials
-
acute cardiovascular events
-
use of anabolic medications
-
epilepsy
-
severe neurological diseases
-
skin lesions in the area of electrodes
-
energy active metals in body
-
pregnancy
-
acute vein thrombosis
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
---|---|---|---|---|---|
1 | Universitätsklinikum Erlangen, Medizinische Klinik 1 | Erlangen | Bavaria | Germany | 91054 |
Sponsors and Collaborators
- University of Erlangen-Nürnberg Medical School
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- CED EMS