FAV: Identifying Risk Factors for Early Arteriovenous Fistula Failure in Haemodialysis Patients
Study Details
Study Description
Brief Summary
The aim of this work is to identify the pre/perioperative factors that predict early AVF failure and to determine minimum vessel diameters that promote AVF function. We also sought to determine whether pre/perioperative factors could predict the key early postoperative vessel factors, namely, AVF blood flow, AVF vein diameter, change in internal AVF vein diameter, skin-AVF distance, and stenosis/thrombosis.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Patients with ESRD with early AVF failure Patients with ESRD who underwent AVF access creation surgery with early AVF failure |
Other: Identification of predictive factors
Evaluation of the following variables : age, sex, body mass index, Diabetes mellitus, vascular disease, hematologic disease, venous thromboembolic disease, antiplatelet or anticoagulant treatments, haemodialysis Catheter Insertion, number of comorbid conditions, Venous diameter, Arterial diameter, AVF type, AVF limb, Anasthesia group
|
| patients with ESRD without early AVF failure Patients with ESRD who underwent AVF access creation surgery without early AVF failure |
Other: Identification of predictive factors
Evaluation of the following variables : age, sex, body mass index, Diabetes mellitus, vascular disease, hematologic disease, venous thromboembolic disease, antiplatelet or anticoagulant treatments, haemodialysis Catheter Insertion, number of comorbid conditions, Venous diameter, Arterial diameter, AVF type, AVF limb, Anasthesia group
|
Outcome Measures
Primary Outcome Measures
- Identification of the pre/perioperative factors that predict early AVF failure [up to 3 months after AVF creation]
Comparison of preoperative and intraoperative results according to composite factors of arteriovenous fistula failure: blood flow ≤ 500 ml/min, postoperative venous internal diameter VID ≤ 5 mm; complications: presence of stenosis, presence of thrombosis; AVF vein depth (external diameter) ≥ 6. The following variables were compared between groups: age (years) , sex (Man/Women), body mass index (kg/m2), Diabetes mellitus (yes/no), vascular disease (yes/no), hematologic disease (yes/no), venous thromboembolic disease (yes/no), antiplatelet or anticoagulant treatments (yes/no), haemodialysis Catheter Insertion (yes/no), the number of comorbid conditions (1, 2, 3 and 4), Venous diameter (mm), Arterial diameter (mm), AVF type (Brachiocephalic/Radiocephalic), AVF limb (left/right), Anasthesia group (local/general)
Secondary Outcome Measures
- Identification of the pre/perioperative factors that predict the early postoperative AVF blood flow [up to 3 months after AVF creation]
Comparison of preoperative and intraoperative results according to AVF blood flow (AVF ≤ 500 ml/min vs AVF > 500 ml/min) for the following variables: age (years) , sex (Man/Women), body mass index (kg/m2), Diabetes mellitus (yes/no), vascular disease (yes/no), hematologic disease (yes/no), venous thromboembolic disease (yes/no), antiplatelet or anticoagulant treatments (yes/no), haemodialysis Catheter Insertion (yes/no), the number of comorbid conditions (1, 2, 3 and 4), Venous diameter (mm), Arterial diameter (mm), AVF type (Brachiocephalic/Radiocephalic), AVF limb (left/right), Anasthesia group (local/general)
- Identification of the pre/perioperative factors that predict the early postoperative venous internal diameter (VID) [up to 3 months after AVF creation]
Comparison of preoperative and intraoperative results according to venous internal diameter (VID ≤ 5 mm vs > 5 mm) for the following variables: age (years) , sex (Man/Women), body mass index (kg/m2), Diabetes mellitus (yes/no), vascular disease (yes/no), hematologic disease (yes/no), venous thromboembolic disease (yes/no), antiplatelet or anticoagulant treatments (yes/no), haemodialysis Catheter Insertion (yes/no), the number of comorbid conditions (1, 2, 3 and 4), Venous diameter (mm), Arterial diameter (mm), AVF type (Brachiocephalic/Radiocephalic), AVF limb (left/right), Anasthesia group (local/general)
- Identification of the pre/perioperative factors that predict the early postoperative stenosis and/or thrombosis [up to 3 months after AVF creation]
Comparison of preoperative and intraoperative results according to stenosis and/or thrombosis (stenosis or thrombosis vs no complications) for the following variables: age (years) , sex (Man/Women), body mass index (kg/m2), Diabetes mellitus (yes/no), vascular disease (yes/no), hematologic disease (yes/no), venous thromboembolic disease (yes/no), antiplatelet or anticoagulant treatments (yes/no), haemodialysis Catheter Insertion (yes/no), the number of comorbid conditions (1, 2, 3 and 4), Venous diameter (mm), Arterial diameter (mm), AVF type (Brachiocephalic/Radiocephalic), AVF limb (left/right), Anasthesia group (local/general)
- Identification of the pre/perioperative factors that predict the early postoperative venous external diameter [up to 3 months after AVF creation]
Comparison of preoperative and intraoperative results according to skin-AVF distance (< 6 mm vs ≥ 6 mm) for the following variables: age (years) , sex (Man/Women), body mass index (kg/m2), Diabetes mellitus (yes/no), vascular disease (yes/no), hematologic disease (yes/no), venous thromboembolic disease (yes/no), antiplatelet or anticoagulant treatments (yes/no), haemodialysis Catheter Insertion (yes/no), the number of comorbid conditions (1, 2, 3 and 4), Venous diameter (mm), Arterial diameter (mm), AVF type (Brachiocephalic/Radiocephalic), AVF limb (left/right), Anasthesia group (local/general)
Eligibility Criteria
Criteria
Inclusion Criteria:
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Adult patients (≥ 18 years)
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Patients who had undergone distal (radioradial and radiocephalic) or proximal arteriovenous fistula (AVF) access creation surgery between 2014 and 2021 at the CHR Metz-Thionville.
Exclusion Criteria:
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Patients under 18 years of age,
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Patients without preoperative venous mapping
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Patients using the fistula for intermittent plasmapheresis
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Patients with a radiobasilic AVF
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | CHR Metz-Thionville/Hopital de Mercy | Metz | France | 57085 |
Sponsors and Collaborators
- Centre Hospitalier Régional Metz-Thionville
Investigators
- Principal Investigator: Zead TUBAIL, MD, CHR Metz Thionville Hopital de Mercy
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- 2022-06Obs-CHRMT