Infective Keratitis in Minia Governate

• Sponsor: Minia University (Other)
• Overall Status: Completed
• CT.gov ID: NCT04894630
• Collaborator: (none)
• Enrollment: 150
• Location: 1
• Arm: 1
• Actual Duration (Months): 25
• Patients Per Site Per Month: 6

Study Details

Study Description

Brief Summary

The purpose of the study is to determine the microbiological aetiology, epidemiological factors, and clinical profile and treatment outcomes of infective keratitis in Ophthalmology department, Minia University. Egypt

Condition or Disease	Intervention/Treatment	Phase
Infective Keratitis	Other: antimicrobial treatment	N/A

Detailed Description

Prospective, non-randomized, observational clinical series of cases, including 150 patients clinically diagnosed as infective corneal ulcer, attending the Ophthalmology Department - Faculty of Medicine. Minia University, Minia, Egypt. From 2018 to 2020.

Detailed history taking and all clinical findings were collected. Corneal scrapings were obtained from patients and subjected to staining and culture for bacterial and fungal pathogens; Bacterial and fungal growth were identified by standard laboratory procedures.

Study Design

• Study Type: Interventional
• Actual Enrollment: 150 participants
• Allocation: N/A
• Intervention Model: Sequential Assignment
• Masking: None (Open Label)
• Primary Purpose: Treatment
• Official Title: Epidemiology, Clinical Profile and Treatment Outcomes of Bacterial and Fungal Keratitis in Minia Governate, Egypt
• Actual Study Start Date: Dec 1, 2018
• Actual Primary Completion Date: Dec 31, 2020
• Actual Study Completion Date: Dec 31, 2020

Arms and Interventions

Arm	Intervention/Treatment
Other: infective keratitis 150 patients with mean age 30 (range 12 to 85 years), 90 patients (60 %) were males and 60 (40%) were females, clinically diagnosed as infective corneal ulcer, attending the Ophthalmology Department - Faculty of Medicine. Minia University, Minia, Egypt. From 2018 to 2020.	Other: antimicrobial treatment; Detailed history taking and all clinical findings were collected. Corneal scrapings were obtained from patients and subjected to staining and culture for bacterial and fungal pathogens; Bacterial and fungal growth were identified by standard laboratory procedures.

Outcome Measures

Primary Outcome Measures

1. Positive smear and culture [1 month]

   positive smear culture for bacteria and fungi

Eligibility Criteria

Criteria

• Ages Eligible for Study: 12 Years to 80 Years
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

• clinically diagnosed as infective corneal ulcer, attending the Ophthalmology Department - Faculty of Medicine - Minia University, Minia, Egypt

Exclusion Criteria:

• healed keratitis

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Minia University	Minya		Egypt	61111

Sponsors and Collaborators

• Minia University

Investigators

• Study Director: Ahmed Abdelghany, ASS PROF, Minia University

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Nabila Abdelhaleem Aboeleyoon Mabrouk, prinicipal investigator, Minia University
• ClinicalTrials.gov Identifier: NCT04894630
• Other Study ID Numbers: 61519
• First Posted: May 20, 2021
• Last Update Posted: May 20, 2021
• Last Verified: May 1, 2021

• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No
• Keywords provided by Nabila Abdelhaleem Aboeleyoon Mabrouk, prinicipal investigator, Minia University: infective keratitis; Bacterial keratitis; Fungal keratitis
• Additional relevant MeSH terms: Keratitis; Anti-Infective Agents; Anti-Bacterial Agents

Study Results

No Results Posted as of May 20, 2021