Inflammatory and Degenerative Muscle Disease

Sponsor
Assiut University (Other)
Overall Status
Not yet recruiting
CT.gov ID
NCT05738590
Collaborator
(none)
60
13.9

Study Details

Study Description

Brief Summary

Correlation between clinical , ultrasonographical, neurophysiological and histopathological findings in muscle diseases of different etiologies.

Condition or Disease Intervention/Treatment Phase
  • Procedure: muscle biopsy

Study Design

Study Type:
Observational
Anticipated Enrollment :
60 participants
Observational Model:
Cohort
Time Perspective:
Cross-Sectional
Official Title:
Neurophysiological, Sonographical and Pathological Findings in Patients With Inflammatory Versus Degenerative Muscle Diseases
Anticipated Study Start Date :
Apr 1, 2023
Anticipated Primary Completion Date :
Mar 31, 2024
Anticipated Study Completion Date :
May 28, 2024

Arms and Interventions

Arm Intervention/Treatment
inflammatory muscle disease

Procedure: muscle biopsy
true cut needle biopsy
Other Names:
  • neurophysiology(nerve conduction,electromyography)
  • muscle ultrasound
  • degenerative muscle disease

    Procedure: muscle biopsy
    true cut needle biopsy
    Other Names:
  • neurophysiology(nerve conduction,electromyography)
  • muscle ultrasound
  • Outcome Measures

    Primary Outcome Measures

    1. microscopic picture of muscle in inflammatory and degenerative muscle disease [1 year]

      true cut needle muscle biopsy is done to differentiate between inflammatory and degenerative muscle disease in microsopic picture

    Secondary Outcome Measures

    1. muscle ultrasound in inflammatory and degenerative muscle disease [1 year]

      muscle ultrasound picture and dimensions in inflammatory and degenerative muscle disease

    2. neurophysiology in inflammatory and degenerative muscle disease [1 year]

      electromyography changes in inflammatory and degenerative muscle disease

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years to 75 Years
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    No
    Inclusion Criteria:
    1. Muscle diseases of different etiologies.

    2. Any age.

    Exclusion Criteria:
    1. Patient refuse to participate.

    2. The anatomy is altered due to severe trauma, tumor , or surgery.

    3. Severe deformity preventing examination.

    Contacts and Locations

    Locations

    No locations specified.

    Sponsors and Collaborators

    • Assiut University

    Investigators

    None specified.

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    Huda Mahmoud Sayed Abdelal, Resident, Assiut University
    ClinicalTrials.gov Identifier:
    NCT05738590
    Other Study ID Numbers:
    • muscle disease neurophysiology
    First Posted:
    Feb 22, 2023
    Last Update Posted:
    Feb 22, 2023
    Last Verified:
    Feb 1, 2023
    Additional relevant MeSH terms:

    Study Results

    No Results Posted as of Feb 22, 2023