The Influence of Meibomian Gland Expression on Corneal Aberrations in MGD Patients
Study Details
Study Description
Brief Summary
To evaluate the influence of corneal-aberrations before and after the meibomian gland thermal massage treatment.
Condition or Disease | Intervention/Treatment | Phase |
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Detailed Description
62 MGD patients treated with meibomian gland thermal massage once a week for 3 to 4 weeks were recruited.The Ocular Surface Disease Index questionnaire; tear film assessment encompassing tear meniscus height and non-invasive keratograph breakup time ; meibography score,corneal fluorescein staining; the Schirmer I test ; expressible meibomian gland, and quality ,anterior and total corneal aberrations were evaluated before and after treatment.
Study Design
Outcome Measures
Primary Outcome Measures
- corneal aberration corneal aberrations [baseline and 1 week after treatment]
Corneal aberrations were measured with a Pentacam。 The anterior corneal wavefront aberration was expanded with normalized Zernike polynomials.The corneal aberration from 3rd to 6th order were recorded as the root mean square (RMS) for analysis.
Eligibility Criteria
Criteria
Inclusion Criteria:
- tear break-up time (BUT) ≤10 seconds or Schirmer I test (SIT) ≤10 mm, the presence of dry eye symptoms, and fluorescein staining (FL) score <3 points and at least one lid margin abnormality and poor meibomian gland expressibility
Exclusion Criteria:
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eyelid structure abnormal(Entropion , ectropion);
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having received any other treatment for MGD within three months
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history of ocular surgery
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contact lens use
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ocular infection
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any type of corneal scarring
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
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1 | Eye Hospital of Wenzhou Medical College | Wenzhou | Zhejiang | China | 325027 |
Sponsors and Collaborators
- Wenzhou Medical University
Investigators
- Study Director: Yune Zhao, Ophthalmology and Optometry Hospital
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- hf-meibomian glands