ILYAD1: Initiative in LYon for Lung cAncer Screening Development - Prevalence Study

Sponsor
Hospices Civils de Lyon (Other)
Overall Status
Completed
CT.gov ID
NCT04240418
Collaborator
(none)
4,595
1
2.5
1864.8

Study Details

Study Description

Brief Summary

Screening at-risk subjects with low-dose computed tomography (CT) efficiently reduces lung cancer specific mortality. However screening efficiency relies on the at-risk population's criteria definition and its participation rate to the screening. In France, there are concerns regarding the participation rates to national cancer screening that are quite low (around 50% and 32% of the eligible population for breast cancer and colorectal cancer respectively). Before organizing national lung cancer screening it is then crucial to determine the factors impacting the at-risk subjects willingness to participate in lung cancer screening.

The Lyon University Hospital is the second biggest hospital in France with more than 23,000 employees distributed among more than 160 professions representing every level of education or working conditions. Its population is heterogeneous and wide enough to perform a prevalence study assessing the willingness to participate among the at-risk population.

ILYAD is a prospective study performed by anonymous questionnaires that will be submitted to the 23,000 employees of the Lyon University Hospital. The study main objective is to evaluate the at-risk population presence in the Lyon University Hospital population, as defined by NELSON criteria and selection criteria for lung cancer screening (PLCOm2012 scoring), and its willingness to participate to a lung-cancer screening with low-dose CT. This might help further efficient national lung cancer screening campaign organization.

Condition or Disease Intervention/Treatment Phase
  • Other: Survey

Study Design

Study Type:
Observational
Actual Enrollment :
4595 participants
Observational Model:
Ecologic or Community
Time Perspective:
Prospective
Official Title:
Initiative in LYon for Lung cAncer Screening Development - Prevalence Study
Actual Study Start Date :
Oct 31, 2020
Actual Primary Completion Date :
Jan 14, 2021
Actual Study Completion Date :
Jan 14, 2021

Arms and Interventions

Arm Intervention/Treatment
Lyon University Hospital employees

Other: Survey
The objective is to evaluate the eligibility of the responders, as defined by NELSON criteria and PLCOm2012 scoring, and their willingness to participate to a lung-cancer screening with low-dose computed tomography.

Outcome Measures

Primary Outcome Measures

  1. Number of employees belonging to the at-risk population for lung cancer and consequently eligible to lung cancer screening. [Day 0 (at inclusion)]

    High-risk ever-smokers are defined as ever-smokers aged 55-74 years old, having smoked >15 cigarettes per day for >25 years or >10 cigarettes for >30 years and with ≤15 years since cessation for quitters.

Eligibility Criteria

Criteria

Ages Eligible for Study:
18 Years and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
  • Aged ≥ 18 years old

  • Employee from the Lyon University Hospital (receiving salary from the Lyon University Hospital)

  • Person who has willingness to respond the survey

Exclusion Criteria:
  • Employees not hired by the Lyon University Hospital

  • Employees who have not willingness to participate in the survey

Contacts and Locations

Locations

Site City State Country Postal Code
1 Hospices Civils de Lyon Lyon France 69000

Sponsors and Collaborators

  • Hospices Civils de Lyon

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Hospices Civils de Lyon
ClinicalTrials.gov Identifier:
NCT04240418
Other Study ID Numbers:
  • ILYAD1_2019
First Posted:
Jan 27, 2020
Last Update Posted:
Jul 13, 2021
Last Verified:
Jul 1, 2021
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms:

Study Results

No Results Posted as of Jul 13, 2021