An Interocular Comparative Study of Unilateral Cataract
Study Details
Study Description
Brief Summary
The purpose of this cross-sectional study is to compare bilateral anterior segment parameters, macular thickness, and BCVA at 3 months after uncomplicated unilateral pediatric cataract extraction with primary IOL implantation to explore any possible interocular differences and their possible relationships.
Condition or Disease | Intervention/Treatment | Phase |
---|---|---|
|
Detailed Description
Great advances have been made in managing pediatric cataracts during the last several decades; these advances have contributed to a decrease in the incidence of postoperative complications and improvement in visual outcomes.Early cataract removal and replacement with an intraocular lens (IOL) represent the most appropriate treatments to avoid irreversible amblyopia.Although screening and timely surgical intervention play a key role in improved best corrected visual acuity (BCVA) among pediatric patients with cataracts, determining the prognosis for an individual remains difficult, particularly for unilateral cataract.
Few studies have focused on the interocular differences in ocular anatomic parameters other than axial length in unilateral pediatric cataract after surgery, the significance of which for the possible interocular visual functional difference remains unclear. Therefore, the investigators conducted this cross-sectional study to compare bilateral anterior segment parameters, macular thickness, and BCVA at 3 months after uncomplicated unilateral pediatric cataract extraction with primary IOL implantation to explore any possible interocular differences and their possible relationships.
Study Design
Outcome Measures
Primary Outcome Measures
- Interocular anatomical parameters in pediatric unilateral cataract patients measured by pentacam [Baseline]
The Parameters are measured by pentacam (Oculus Inc., Wetzlar, Germany), a rotating Scheimpflug camera.
- Visual function in pediatric unilateral cataract patients measured by Teller Acuity Cards [Baseline]
The visual function is measured by Teller Acuity Cards (Stereo Optical Company, Inc., IL, USA).
Eligibility Criteria
Criteria
Inclusion Criteria:
-
Children with uncomplicated surgeries
-
Children who were younger than 10 years old
-
Children with unilateral total cataract
Exclusion Criteria:
-
Premature birth
-
Microphthalmia
-
Micro-or Megalocornea
-
Keratoconus
-
Glaucoma
-
Traumatic or complicated cataracts
-
Vitreous and retinal diseases
-
Any previous surgeries
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
---|---|---|---|---|---|
1 | Zhongshan Ophthalmic Center, Sun Yat-sen University | Guangzhou | Guangdong | China | 510060 |
Sponsors and Collaborators
- Sun Yat-sen University
- Ministry of Health, China
Investigators
- Principal Investigator: Haotian Lin, M.D., Ph.D, Zhongshan Ophthalmic Center, Sun Yat-sen University
- Study Chair: Yizhi Liu, M.D., Ph.D, Zhongshan Ophthalmic Center, Sun Yat-sen University
- Study Director: Weirong Chen, M.D., Zhongshan Ophthalmic Center, Sun Yat-sen University
Study Documents (Full-Text)
None provided.More Information
Additional Information:
Publications
- Hutcheson KA. Application of new ophthalmic technology in the pediatric patient. Curr Opin Ophthalmol. 2007 Sep;18(5):384-91. Review.
- Lin H, Chen W, Luo L, Congdon N, Zhang X, Zhong X, Liu Z, Chen W, Wu C, Zheng D, Deng D, Ye S, Lin Z, Zou X, Liu Y. Effectiveness of a short message reminder in increasing compliance with pediatric cataract treatment: a randomized trial. Ophthalmology. 2012 Dec;119(12):2463-70. doi: 10.1016/j.ophtha.2012.06.046. Epub 2012 Aug 24.
- CCPMOH2016-China-3