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Mass Treatment T Solium Community Study

Sponsor
National Institute of Allergy and Infectious Diseases (NIAID) (NIH)
Overall Status
Terminated
CT.gov ID
NCT00138359
Collaborator
(none)
4,200
Enrollment
1
Location
1
Duration (Months)
4123.8
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Investigators from Cayetano Heredia University and Johns Hopkins University are doing this study. They want to see how people and pigs get infected with a parasite, called cysticercus (known as "pig triquina"). Cysticercus attacks the meat of pigs and the brains of people. In the intestine, the parasite is known as "solitaria". This study is to see how treatment in both people and pigs works to control the disease.

Condition or Disease Intervention/Treatment Phase
N/A

Detailed Description

This is a prospective intervention study to determine the efficacy and persistence of effect over time of a single, chemotherapy intervention in both the human and porcine population. Four villages will be selected to be treated against T solium adult (in humans) and larval forms (in pigs), and two villages will receive no intervention and will serve as control villages. Pigs in control villages will be followed during 3 months only, and then the human and porcine populations will receive the intervention treatment. The effect of this intervention will be measured by the prevalence of infection in pigs and parasitic burden of infected pigs at month 3, 6, 9, and 12.

Study Design

Study Type:
Interventional
Allocation:
Non-Randomized
Intervention Model:
Single Group Assignment
Masking:
None (Open Label)
Primary Purpose:
Treatment
Official Title:
The Effect of a Single Control Intervention in the T Solium Life Cycle
Study Start Date :
Dec 1, 2004
Study Completion Date :
Jan 1, 2005

Outcome Measures

Primary Outcome Measures

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    2 Years and Older
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    Yes
    Inclusion Criteria:
    • All consenting individuals older than two years living in the study villages (6 endemic communities of the Northern coast of Peru)
    Exclusion Criteria:
    • Pregnancy (for antiparasitic treatment only).

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Universidad Peruana Cayetano Heredia Lima Peru

    Sponsors and Collaborators

    • National Institute of Allergy and Infectious Diseases (NIAID)

    Investigators

    None specified.

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    , ,
    ClinicalTrials.gov Identifier:
    NCT00138359
    Other Study ID Numbers:
    • 04-043
    First Posted:
    Aug 30, 2005
    Last Update Posted:
    Aug 27, 2010
    Last Verified:
    Dec 1, 2006
    Keywords provided by , ,
    T solium, cysticercus, pig triquina, solitaria, intestinal parasites, Niclosamide, tapeworms, Taeniasis
    Additional relevant MeSH terms:
    Intestinal Diseases, Parasitic
    Niclosamide

    Study Results

    No Results Posted as of Aug 27, 2010