EBLOUI: Tolerance to Light for Patients Suffering From Keratitis
In order to develop an innovative device to study infectious keratitis, we need to illuminate the cornea of patients suffering from an infectious keratitis with red or near-infrared light. Because of technical reasons the shortest possible wavelength (red) presents advantages.
|Condition or Disease||Intervention/Treatment||Phase|
The aim of this preliminary study is to measure the maximal intensity tolerated during illumination with 6 wavelength corresponding : 2 red, 2 far red and 1 near infrared lights in order to determine the shortest wavelength well tolerated by patients, in comparison with the standard blue light illumination.
Arms and Interventions
|Experimental: Light exposure|
The keratitis eye of the patient is exposed to 6 lights with increasing intensity according to a constant speed. The patients switch off the light when the discomfort is too elevated
Device: Light exposure
The 6 lights used randomly are : 482nm =standard blue light illumination, 650nm, 675nm, 700nm, 750nm 800nm
Primary Outcome Measures
- Light intensity [At the inclusion]
For each wavelength, the highest light intensity tolerated by the patient is measured (mWatts/cm² )
Secondary Outcome Measures
- Severity of the keratitis [At the inclusion]
It is determined by slit lamp. The result is "severe" or "not severe"
Social security insurance
Suspected infectious keratitis (clinically defined. No lab testing required)
Signed informed consent
Aphakia (absence of lens)
Contacts and Locations
|1||CHU de Saint-Etienne||Saint-Étienne||France||42000|
Sponsors and Collaborators
- Centre Hospitalier Universitaire de Saint Etienne
- University of Saint-Etienne
- Principal Investigator: Gilles THURET, MD PhD, CHU de Saint-Etienne
Study Documents (Full-Text)None provided.