Limitations of Using a Sheimpflug Image-Based Device for Measuring Anterior Chamber Depth in Pseudophakic Eyes

• Sponsor: Far Eastern Memorial Hospital (Other)
• Overall Status: Completed
• CT.gov ID: NCT00712231
• Collaborator: (none)
• Enrollment: 184
• Duration (Months): 1

Study Details

Study Description

Brief Summary

There have been numerous studies comparing various ACD measurements in phakic eyes,while researches comparing ACD in pseudophakic eyes are less extensive. With the recent popularity of presbyopia correction, measuring the ACD will facilitate differentiating pseudophakic accommodation from pseudoaccommodation. It is thus mandatory to verify the accuracy of ACD measurement of these devices since the innovation of various IOLs in the recent decade makes this task more complicated. In this study, we will assess the limitations of using Pentacam for ACD measurement in pseudophakic eyes and compare Pentacam measurement with IOLMaster and A-scan measurements.

Condition or Disease	Intervention/Treatment	Phase
Cataract

Detailed Description

In this prospective study, ACD was measured in 90 phakic and 94 pseudophakic eyes by Pentacam, IOLMaster and A-scan. Correlations and differences between the three measurements were investigated. The accuracy in detecting the anterior lens surface in pseudophakic eyes was also assessed.Differences in ACD-Pen, ACD-IOLM, and ACD-A were analyzed using one-way analysis of variance (ANOVA). When an overall significance of P< 0.05 was obtained, pair-wise comparisons were made using Tukey's multiple comparison t tests. The association between ACD-Pen, ACD-IOLM, and ACD-A was assessed using Pearson's correlation test. The distribution of erroneous ACD-Pen measurement for the three IOLs was analyzed with the chi-square test. In all analyses, P <0.05 was considered statistically significant.

Study Design

• Study Type: Observational
• Actual Enrollment: 184 participants
• Observational Model: Cohort
• Time Perspective: Prospective
• Official Title: To Assess the Degree of Agreement of Anterior Chamber Depth Measurements by 2 Optical Devices (Pentacam and IOLMaster) and Compare Them With Contact Ultrasound A-Scan in Phakic and Pseudophakic Eyes.
• Study Start Date: Jan 1, 2008
• Actual Primary Completion Date: Feb 1, 2008
• Actual Study Completion Date: Feb 1, 2008

Arms and Interventions

Arm	Intervention/Treatment
phakic eyes the cases did not accept any intraocular surgery
pseudophakic eyes tht cases did not accept any intraocular surgery expect for cataract surgery

Outcome Measures

Primary Outcome Measures

Eligibility Criteria

Criteria

• Ages Eligible for Study: 40 Years to 80 Years
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

• Phakic group: randomized

• Pseudophakic eyes : the cases accepted cataract surgery

Exclusion Criteria:

• Previous ocular trauma or intraocular surgery other than cataract surgery;

• Contact lens use in the past two months;

• Use of medication that might affect the pupil; corneal disease or ocular infection;

• History of ocular disease, such as

• Dry eye syndrome

• Uveitis

• Glaucoma

• Ocular tumor

• Cases with any surgical complications were also excluded.

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

• Far Eastern Memorial Hospital

Investigators

• Principal Investigator: Shu-Wen Chang, Far Eastern Memorial Hospital

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• ClinicalTrials.gov Identifier: NCT00712231
• Other Study ID Numbers: FEMH97007
• First Posted: Jul 9, 2008
• Last Update Posted: Jul 9, 2008
• Last Verified: Jul 1, 2008

• Keywords provided by , ,: pseudophakic; anterior chamber depth; Pentacam
• Additional relevant MeSH terms: Cataract

Study Results

No Results Posted as of Jul 9, 2008