Lung Health After Tuberculosis: Clinical and Functional Assessment in Post Pulmonary Tuberculosis Egyptian Patients.
Study Details
Study Description
Brief Summary
Some of pulmonary tuberculous patients who completed their medication course experience lung function impairment
Condition or Disease | Intervention/Treatment | Phase |
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Detailed Description
Some of pulmonary tuberculous patients who completed their medication course experience lung function impairment which may influence their quality of life. However, the pattern and nature of post-tuberculosis lung impairment is still not identified. Thus, the aim of this study was to determine the type and degree of lung physiology changes in previously treated tuberculous patients which latter may affect their quality of life; thus helping clinicians for early diagnosis of lung impairment, especially in tuberculous endemic areas.
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
---|---|
Cured pulmonary Tuberculosis patients 6 months after a completed course of anti-tuberculosis therapy |
Diagnostic Test: spirometry
Patient do spirometry
|
Outcome Measures
Primary Outcome Measures
- Post tuberculosis lung functional impairment [6 months]
spirometry abnormality either: restrictive, obstructive, or mixed
- post tuberculosis persistent clinical symptoms [6 months]
either cough , sputum , breathlessness, hemoptysis
- Grading of obstruction function: [6 months]
grading according to GOLD : mild , moderate , severe , very severe
Eligibility Criteria
Criteria
Inclusion Criteria:
- Patient completed an outpatient course of standard first line anti-tuberculosis therapy and declared as cured
Exclusion Criteria:
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Smoker (to avoid spirometry biases).
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Extrapulmonary tuberculosis cases
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Multidrug resistant tuberculosis
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known contraindications to spirometry testing
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Individuals with chest wall deformities or neuromuscular diseases
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Patients who failed to achieve acceptability and reproducibility criteria of the spirometry test
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Defaulter cases or irregular treatment,
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known coexisting chronic lung disease as history of asthma or interstitial lung diseases
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A history of illicit drug use
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Patients with comorbidities: renal and hepatic insufficiency, heart diseases and metabolic disorders.
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
---|---|---|---|---|---|
1 | Chest Department-faculty of medicine-Assuit university | Assuit | Egypt |
Sponsors and Collaborators
- Assiut University
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- 5884