Lung Ultrasound Changes in Covid 19 Patients Discharged From Hospital

Sponsor

Chelsea and Westminster NHS Foundation Trust (Other)

Overall Status

Completed

CT.gov ID

NCT05062603

Collaborator

(none)

Enrollment

Location

4.8

Actual Duration (Months)

4.8

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Lung ultrasound has been used to help diagnose COVID-19 as an alternative to CT scanning and chest X-ray. CT scanning is onerous and there are difficulties taking critically unwell patients there as well as decontamination issues.

Chest X-ray misses up to 40% of COVID diagnoses. Although lung ultrasound can diagnose, the investigators do not know how long these lung ultrasound changes last. The investigators would like to follow up patients to characterise the pattern of changes and how long they last. This is particularly important given a potential second surge of COVID-19 is looming and the investigators would like to know if lung ultrasound changes are new or old in patients presenting during this second wave and in the future.

Condition or Disease	Intervention/Treatment	Phase
Covid19 Coronavirus Coronavirus Infection SARS-CoV Infection

Detailed Description

Ultrasound has been invaluable during this pandemic to diagnose COVID-19. The investigators have used it alongside CT scanning to rationalise the number of CT scans especially when patients are unstable. The investigators do not know how long these changes last on lung ultrasound after discharge and the investigators wish to study this.

This is because patients will start presenting shortly who have a history of COVID-19 with acute medical problems and if the investigators are to use lung ultrasound again the investigators would like to know whether the changes the investigators see are new or old.

This is vitally important before a second surge and especially so before winter. This may also facilitate triage of patients from the front door in the Emergency department to different areas (such as COVID-19 zones or clean areas).

Study Design

Study Type:

Observational

Actual Enrollment :

23 participants

Observational Model:

Cohort

Time Perspective:

Prospective

Official Title:

Prospective Observational Study Looking at Lung Ultrasound Changes During Recovery From COVID19 Infection

Actual Study Start Date :

Jul 9, 2020

Actual Primary Completion Date :

Dec 1, 2020

Actual Study Completion Date :

Dec 1, 2020

Outcome Measures

Primary Outcome Measures

Assessment of lung ultrasound changes over the time period of follow up. [Approximately 3 months or until the ultrasound changes in the lung had normalised]
The assessment will determine how long it takes for lung ultrasound changes to resolve following discharge from hospital in patients who were diagnosed with COVID-19 (unit of measurement: days).

Secondary Outcome Measures

Exploration of ongoing symptoms [Approximately 3 months or until the ultrasound changes in the lung had normalised]
Ongoing symptoms will be explored by using screening questions.

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria:

18 years old or older
Confirmed COVID-19 positive with changes on CXR or CT scan
Having had an initial lung ultrasound in the Emergency department when they were first admitted into the hospital.