Lung Ultrasound in Procalcitonin- Guided Antibiotic Discontinuation in Ventilator Associated Pneumonia
Study Details
Study Description
Brief Summary
Ventilator Associated pneumonia (VAP) is associated with longer ICU length of stay, prolonged mechanical ventilation, and increased use of antimicrobials, health-care cost and mortality . Acute respiratory infections (ARIs) comprise a large and heterogeneous group of infections, including bacterial infections, viral infections, and infections of other etiologies. Early initiation of adequate antibiotic therapy is the cornerstone in the treatment. However, overuse of antibiotics and prolonged duration of antibiotic therapy in patients with bacterial ARIs in the hospital and intensive care setting is associated with increased resistance for common bacteria, high costs, and adverse drug reactions.
Condition or Disease | Intervention/Treatment | Phase |
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Study Design
Outcome Measures
Primary Outcome Measures
- correlation between lung ultrasound and procalcitonin. [7 days]
Eligibility Criteria
Criteria
Inclusion Criteria:
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18 years old or greater
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Ventilator associated pneumonia (VAP) with positive sputum culture.
Exclusion Criteria:
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pregnancy,
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use of immunosuppressive agents except for steroids,
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neutropenia (white blood cell count ≤1000/mL)
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patients whose primary diagnosis was community acquired pneumonia and other source of infection.
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
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1 | Ain Shams University | Cairo | Egypt |
Sponsors and Collaborators
- Ain Shams University
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- R 49 / 2020