Effect of Neurodynamic Mobilization on Median Nerve Conduction Velocity in Carpal Tunnel Syndrome

Sponsor
Cairo University (Other)
Overall Status
Not yet recruiting
CT.gov ID
NCT05788471
Collaborator
(none)
40
1
2
4.5
9

Study Details

Study Description

Brief Summary

The purpose of this study is to examine:
  1. The effect of neurodynamic mobilization on the sensory and motor median nerve conduction velocity in carpal tunnel syndrome.

  2. The effect of neurodynamic mobilization on the wrist pain in carpal tunnel syndrome.

  3. The effect of neurodynamic mobilization on the hand function in carpal tunnel syndrome.

Condition or Disease Intervention/Treatment Phase
  • Other: conventional Treatment
  • Other: Neurodynamic mobilization
N/A

Detailed Description

The findings of this study will provide physiotherapists with information to know if neurodynamic mobilization techniques is effective on median nerve conduction velocity in carpal tunnel syndrome also this will improve our body of knowledge about the best modalities for treating carpal tunnel syndrome. The finding of this study may help carpal tunnel syndrome patients to avoid the exposing to complications as a result of compression of median nerve in carpal tunnel syndrome.

Study Design

Study Type:
Interventional
Anticipated Enrollment :
40 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Masking:
Double (Participant, Investigator)
Primary Purpose:
Treatment
Official Title:
Effect of Neurodynamic Mobilization on Median Nerve Conduction Velocity in Carpal Tunnel Syndrome
Anticipated Study Start Date :
Apr 1, 2023
Anticipated Primary Completion Date :
Jun 15, 2023
Anticipated Study Completion Date :
Aug 15, 2023

Arms and Interventions

Arm Intervention/Treatment
Active Comparator: Conventional treatment group

Twenty patients will receive conventional treatment in the form of superficial heat, ultrasound with freq of 1 MHz, pulsed mode 1:4 for 5 min and stretching exercise to lumbrical muscles of the hand.

Other: conventional Treatment
It consists of Superficial heat, Ultrasound therapy and stretching exercise to lumbrical muscles of the hand.

Experimental: Neurodynamic mobilization therapy group

Twenty patients will receive neurodynamic mobilization therapy (upper limb tension test 1) in addition to conventional treatment.

Other: conventional Treatment
It consists of Superficial heat, Ultrasound therapy and stretching exercise to lumbrical muscles of the hand.

Other: Neurodynamic mobilization
It is the mobilisation of the nervous system as an approach to physical treatment of pain. The treatment and or assessment relies on influencing pain physiology via the mechanical treatment of neural tissues and non-neural structures surrounding the nervous system.

Outcome Measures

Primary Outcome Measures

  1. Assessing the change in nerve conduction velocity of the median nerve. [at baseline and after 4 weeks of intervention]

    By using Electromyography apparatus measuring nerve conduction velocity of the median nerve. (motor and sensory in m/s)

  2. Assessing the change in wrist joint pain [at baseline and after 4 weeks of intervention]

    By using Pressure pain threshold (PPT) is defined as the minimal amount of pressure that produces pain. A simple handheld pressure algometer (PA) with a spring is commonly used, although more sophisticated electrical devices with a strain or pneumatic pressure gauge have been developed. They hold the peak force or pressure (kp (kilopond) = 10 N, Newton = 100 kPa (kilopascal)) until tared, and some may also be connected to a computer and thus have continuous output. PPT measured with a probe 1.6 mm in diameter or larger reflects the tenderness of deep tissues as anesthesia of skin only affects the results of smaller probes.

  3. Assessing the change in functional activity of the hand [at baseline and after 4 weeks of intervention]

    By using Modified DASH questionnaire will be used for functional activity of the hand. The Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire is a 30-item questionnaire that looks at the ability of a patient to perform certain upper extremity activities. This questionnaire is a self-report questionnaire that patients can rate difficulty and interference with daily life on a 5 point Likert scale. The QuickDASH tool uses a 5-point Likert scale from which the patient can select an appropriate number corresponding to his/her severity/function level.

Eligibility Criteria

Criteria

Ages Eligible for Study:
20 Years to 50 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
  • Forty carpal tunnel syndrome patients.

  • All participants referred from a physician.

  • Their ages range from 20-50 years old.

  • Both genders will participate in the study.

  • Their BMI ranges between 18.5-24.9kg/m2.

  • All participants have carpal tunnel syndrome at least in one hand.

  • All participants suffering from mild to moderate carpal tunnel syndrome.

Exclusion Criteria:
  • Previous or current disease or trauma that might affect one or both upper limbs.

  • Metabolic diseases that might associated with entrapment neuropathy such as diabetes mellitus, thyroid diseases, and autoimmune diseases.

  • Pregnant women.

  • Participants with congenital hand deformities.

  • History of hand surgery.

  • Sever cases of carpal tunnel syndrome that suffering from weakness of hand grip and atrophy of thenar muscle.

Contacts and Locations

Locations

Site City State Country Postal Code
1 Outpatient clinic faculty of physica therapy cairo university Dokki Egypt

Sponsors and Collaborators

  • Cairo University

Investigators

  • Principal Investigator: Raghda Ahmed, Cairo University

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Raghda Ahmed Mohammed Ebrahim, Principal Investigator, Cairo University
ClinicalTrials.gov Identifier:
NCT05788471
Other Study ID Numbers:
  • Raghda Ahmed_PhD
First Posted:
Mar 29, 2023
Last Update Posted:
Mar 29, 2023
Last Verified:
Mar 1, 2023
Individual Participant Data (IPD) Sharing Statement:
Undecided
Plan to Share IPD:
Undecided
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms:

Study Results

No Results Posted as of Mar 29, 2023