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Movement Disorders Analysis Using a Deep Learning Approach

Sponsor
Hospital Avicenne (Other)
Overall Status
Completed
CT.gov ID
NCT04974034
Collaborator
(none)
50
Enrollment
1
Location
19
Actual Duration (Months)
2.6
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Bradykinesia is a key parkinsonian feature yet subjectively assessed by the MDS-UPDRS score, making reproducible measurements and follow-up challenging.

In a Movement Disorder Unit, the investigators acquired a large database of videos showing parkinsonian patients performing Movement Disorder Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS) part III protocols.

Using a Deep Learning approach on these videos, the investigators aimed to develop a tool to compute an objective score of bradykinesia from the three upper limb tests described in the Movement Disorder Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS) part III.

Condition or Disease Intervention/Treatment Phase

    Study Design

    Study Type:
    Observational
    Actual Enrollment :
    50 participants
    Observational Model:
    Cohort
    Time Perspective:
    Retrospective
    Official Title:
    Movement Disorders Analysis Using a Deep Learning Approach
    Actual Study Start Date :
    Jun 1, 2019
    Actual Primary Completion Date :
    Nov 18, 2020
    Actual Study Completion Date :
    Dec 31, 2020

    Outcome Measures

    Primary Outcome Measures

    1. Movement Disorder Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS) part III score [1 day]

      Automatic Movement Disorder Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS) part III for hand bradykinesia including the three following specific tasks (finger tapping, hand movements and pronation-supination movements of hand). The minimum score is 0. The maximum score is 12 Higher scores mean wors outcome

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years and Older
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    Yes
    Inclusion Criteria:
    • Age > 18 years
    Exclusion Criteria:
    • Refusal of participation

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Hospital Avicenne Bobigny Seine Saint Denis France 93000

    Sponsors and Collaborators

    • Hospital Avicenne

    Investigators

    • Principal Investigator: ClĂ©ment Desjardins, MD, Hospital Avicenne
    • Study Director: Bertrand Degos, MD,PhD, Hospital Avicenne

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    Desjardins Clement, Neurology Resident, Hospital Avicenne
    ClinicalTrials.gov Identifier:
    NCT04974034
    Other Study ID Numbers:
    • CLEA-2019-83
    First Posted:
    Jul 23, 2021
    Last Update Posted:
    Jul 23, 2021
    Last Verified:
    Jul 1, 2021
    Individual Participant Data (IPD) Sharing Statement:
    Undecided
    Plan to Share IPD:
    Undecided
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Keywords provided by Desjardins Clement, Neurology Resident, Hospital Avicenne
    Deep Learning
    Bradykinesia
    Parkinson Disease
    Additional relevant MeSH terms:
    Parkinson Disease
    Movement Disorders
    Parkinsonian Disorders
    Hypokinesia

    Study Results

    No Results Posted as of Jul 23, 2021