A Cohort Study of Hydatidiform Mole
Study Details
Study Description
Brief Summary
The purpose of this study is to construct a cohort for the hydatidiform mole.
Condition or Disease | Intervention/Treatment | Phase |
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Detailed Description
After being informed about the study and potential risks, all patients who meet the eligibility requirements will be enrolled.
Study Design
Outcome Measures
Primary Outcome Measures
- Malignant trophoblastic tumor [4.5 years]
Patients with hydatidiform mole develop malignant trophoblastic tumor. The Federation of International of Gynecologists and Obstetricians criteria for diagnosis of postmolar gestational trophoblastic neoplasia were as follows: (1) when the plateau of human chorionic gonadotrophin (hCG) lasts for four measurements over a period of 3 weeks or longer; that is, days 1, 7, 14, 21; (2) when there is a rise in hCG for three consecutive weekly measurements over at least a period of 2 weeks or more; days 1, 7, 14; (3) If there is a histologic diagnosis of choriocarcinoma.
Eligibility Criteria
Criteria
Inclusion Criteria:
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Patients who are diagnosed with hydatidiform mole (including: complete hydatidiform mole/partial hydatidiform mole; one of twins with hydatidiform mole; ectopic pregnancy hydatidiform mole; macroscopic or microscopic hydatidiform changes indicating early complete or partial hydatidiform mole can not be excluded; atypical placental site nodule) for the first time;
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Age 13-55 years old;
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Obtain informed consent and sign an informed consent form
Exclusion Criteria:
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Patients who are unable to cooperate with the investigation such as mental disorders or cognitive impairment
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No histopathology diagnosis;
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Patients with other malignancies
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- Women's Hospital School Of Medicine Zhejiang University
Investigators
- Principal Investigator: Weiguo Lv, PhD, Women's Hospital School Of Medicine Zhejiang University
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- IRB-20220312-R