DRAMMATIC: S1803, Lenalidomide +/- Daratumumab/rHuPh20 as Post-ASCT Maintenance for MM w/MRD to Direct Therapy Duration
Study Details
Study Description
Brief Summary
Patients are enrolled to screening (Reg Step 1) prior to or after ASCT but prior to Reg Step 2. Patients are followed until they will begin Maintenance and then registered to Reg Step 2 (first randomization). Patients are randomized between Lenalidomide for 2 years and Lenalidomide + Daratumumab/rHuPH20. After 2 years of Maintenance, MRD is assessed to guide further therapy. MRD-positive patients will continue with the assigned treatment. MRD-negative patients will be further randomized (Reg Step 3) to either continue or discontinue the assigned treatment. Patients are treated for up to 7 years from Step 2 reg and followed for up to 15 years.
Condition or Disease | Intervention/Treatment | Phase |
---|---|---|
Phase 3 |
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
---|---|
No Intervention: Study Entry / Screening Study entry/screening to follow patient until Maintenance. |
|
Active Comparator: Arm 1: Lenalidomide Lenalidomide 10 mg/day, D1-28, q28 days for 3 cycles, then 15 mg/day, D1-28 for up to 2 years from starting treatment. |
Drug: Lenalidomide
Commercially available intervention
Other Names:
|
Experimental: Arm 2: Lenalidomide + Daratumumab/rHuPH20 Lenalidomide 10 mg/day, D1-28, q28 days for 3 cycles, then 15 mg/day, D1-28 for up to 2 years from starting treatment. Plus Daratumumab/rHuPH20 1800 mg/30,000 units D1, 8, 15, 22 q 28 days for 2 cycles, then D 1 and 15 q 28 days for cycles 3-6 then D1 q 28 days for subsequent cycles for up to 2 years from starting treatment. |
Drug: Lenalidomide
Commercially available intervention
Other Names:
Drug: Daratumumab/rHuPH20
SWOG-Held IND
|
Active Comparator: Arm 1a: Continue Lenalidomide MRD+ or MRD- and randomized to Arm 1a: Lenalidomide 10 mg/day, D1-28, q28 days for 3 cycles, then 15 mg/day, D1-28 for up to 7 years from starting treatment. |
Drug: Lenalidomide
Commercially available intervention
Other Names:
|
No Intervention: Arm 1b: Stop Lenalidomide MRD- and randomized to Arm 1b: Discontinue protocol therapy. |
|
Active Comparator: Arm 2a: Continue Lenalidomide + Daratumumab/rHuPH20 MRD+ or MRD- and randomized to Arm 2a: Lenalidomide 10 mg/day, D1-28, q28 days for 3 cycles, then 15 mg/day, D1-28 for up to 7 years from starting treatment. Plus Daratumumab/rHuPH20 1800 mg/30,000 units D1, 8, 15, 22 q 28 days for 2 cycles, then D 1 and 15 q 28 days for cycles 3-6 then D1 q 28 days for subsequent cycles for up to 7 years from starting treatment. |
Drug: Lenalidomide
Commercially available intervention
Other Names:
Drug: Daratumumab/rHuPH20
SWOG-Held IND
|
No Intervention: Arm 2b: Stop Lenalidomide + Daratumumab/rHuPH20 MRD- and randomized to Arm 2b: Discontinue protocol therapy. |
Outcome Measures
Primary Outcome Measures
- Overall Survival [From date of intial randomization until death due to any cause, assessed up to 15 years]
Overall survival will evaluated using a weighted log-rank test and will be compared between primary treatment arms. All eligible patients with valid consent will be included in the analysis. Patients last known to be alive are censored at the date of last contact.
Secondary Outcome Measures
- Progression Free Survival [From date of intial randomization until progression or death due to any cause, whichever occurs first, assessed up to 7 years]
Progression-free survival will evaluated using a weighted log-rank test and will be compared between primary treatment arms. All eligible patients with valid consent will be included in the analysis. Patients last known to be progression-free and alive are censored at the date of last contact.
- Response (PR or better) [From date of initial randomization until date of best response while on study treatment.]
Per International Uniform Response Criteria for Multiple Myeloma PR- ≥ 50% reduction in size of soft tissue plasmacytomas & plasma cells; ≥ 50% decrease in serum & reduction in urine M protein ≥ 90% or to < 200 mg/24hr or ≥ 50% decrease in difference in uninvolved & involved serum free light chain levels; VGPR- PR + Serum and urine M proteins detectable by immunofixation but not on electrophoresis or ≥ 90% reduction in serum M protein & urine M protein < 100 mg/24 hrs; uPR- 1 objective status of PR, but confirmation studies are not done, or do not meet the requirements necessary to confirm response; SD- does not meet criteria for sCR, CR, VGPR, PR or PROG; PROG- new or increase in size of existing bone lesions or soft tissue plasmacytomas/ development of hypercalcemia attributable solely to MM/ ≥ 25% increase from baseline/ lowest response level of either serum or Urine M protein, difference in involved & uninvolved serum free light chain level or bone marrow plasma cell percentage.
- MRD Negativity [24 months from initial randomization]
The rate of MRD response will be calculated as the number of patients who achieved MRD response divided by the number of eligible patients; patients without a conclusive MRD results will be included as non-responders. Comparisons between arms will be made using a stratified Cochran-Mantel-Haenszel test. MRD data will be collected from the central testing laboratory, including percent of cells detected and total cells collected. Unless the sample is limiting, 5 x 106 events are collected for a standard multiple myeloma MRD sensitivities of 0.0001%. MRD negativity will be defined as no templates observed at a sensitivity of 1 in a million cells assessed, with a minimum of 1 million cells being assessed. MRD positivity will be defined as any templates observed regardless of the number of cells analyzed, or non-diagnostic specimens, including if the reference specimen from diagnosis is not able to be sequenced.
Other Outcome Measures
- Toxicity assessment [From the time of intial randomization for up to 7 years.]
All randomized patients that have initiated treatment will be considered evaluable for toxicity analyses. The maximum Grade for each toxicity will be recorded for each patient, and frequency tables will be reviewed to determine toxicity patterns.
Eligibility Criteria
Criteria
Registration Step 1 Except where otherwise indicated below that test is required in a shorter timeframe, all tests for establishing baseline disease status must be completed within 60 days prior to registration. All test results must be documented on the Baseline Tumor Assessment Form for Multiple Myeloma and the Onstudy Form.
Inclusion Criteria
-
Patients must have had a confirmed diagnosis of symptomatic multiple myeloma (See Section 4.1) that required systemic induction therapy prior to autologous stem cell transplantation (ASCT).
-
Patients with disease measurable by serum light chain assay alone are eligible (defined as >/= 100 mg/L on involved light chain).
-
Patients must be registered to Step 1 prior to registration to Step 2. Registration to Step 1 may take place prior to or after autologous stem cell transplant (ASCT), but after completion of induction therapy.
-
Patients must have initiated induction therapy within 12 months prior to registration Step 1 and have received at least two cycles of induction therapy.
-
Patients must be willing and able to take DVT prophylaxis (aspirin, low molecular weight heparin, warfarin, or equivalent oral anticoagulation).
-
Patients must be >/= 18 and </= 75 years of age at time of registration to Step 1.
-
Patients must have history and physical exam within 28 days prior to registration.
-
Patients must have Zubrod Performance Status </= 2.
-
Patients must have evidence of adequate renal function, as defined by (1) creatinine clearance (CrCl) >/= 30 mL/min., as measured by a 24-hour urine collection, or estimated by the Cockcroft and Gault formula, or (2) serum creatinine < 2.5 mg/dL. Values must be obtained within 28 days prior to registration.
-
Patients must have adequate hepatic function defined by the following within 42 days prior to registration:
-
Total bilirubin </=1.5 x IULN (institutional upper limit of the norm) AND
-
AST and ALT </=3.0 x IULN
-
Patients must meet one of the following criteria:
-
Be acceptable for transplant per institutional guidelines and the criteria evidencing this must be documented on the S1803 Onstudy Form. (See Appendix 18.3 for standard transplant eligibility guidelines. Note that these are guidelines and not required criteria.) OR
-
Have completed autologous stem cell transplant within 180 days prior to registration (see also Section 5.2a).
-
Patient's with human immunodeficiency virus (HIV) are eligible providing they are on effective antiretroviral therapy and have undetectable viral load at their most previous viral load test and within 6 months prior to registration.
-
Patients must be able to take and swallow oral medication (capsules) whole. Patients may not have any known impairment of gastrointestinal function or gastrointestinal disease that may significantly alter the absorption of study drug (e.g. ulcerative disease, uncontrolled nausea, vomiting, diarrhea, malabsorption syndrome, or small bowel resection).
-
For patients who have not yet received transplant: Patients must be willing and able to return to the transplant center for their assigned treatment after randomization. Note that patients need not have a direct relationship with the transplant center in order to register.
-
Patients must submit specimens for MRD as outlined in Section 15.1. See Section 15.1 for further information, including specimen submission timepoints. Note that patients are not ineligible based solely on archival specimens being unavailable.
-
Patients must be offered participation in specimen banking for future research. With patient's consent, specimens must be submitted as outlined in Section 15.2.
-
Patients must be informed of the investigational nature of this study and must sign and give written informed consent in accordance with institutional and federal guidelines.
-
As a part of the OPEN registration process (see Section 13.3 for OPEN access instructions) the treating institution's identity is provided in order to ensure that the current (within 365 days) date of institutional review board approval for this study has been entered in the system.
Exclusion Criteria
-
Patients with smoldering myeloma are not eligible. Patients with purely non-secretory MM as measured by electrophoresis and immunofixation and the absence of Bence Jones proteins in the urine are not eligible. Patients must have measurable M protein in the serum (defined as >/= 0.5g/dL) or urine (defined as >/= 200 mg/24h). Patients with plasma cell leukemia are not eligible.
-
Patients must not have any organ involvement by amyloidosis or evidence of amyloidosis related organ dysfunction.
-
Patients must not have progressive disease at any time prior to registration.
-
Patients must not be refractory to either lenalidomide or daratumumab/rHuPH20.
-
Patients must not be intolerant to either lenalidomide or daratumumab/rHuPH20.
-
Patients must not have received any investigational agents within 14 days prior to registration.
-
Patients must not have chronic obstructive pulmonary disease with a forced expiratory volume in 1 second (FEV1) < 50% of predicted normal. FEV1 is required for patients suspected of having chronic obstructive pulmonary disease and are not eligible if FEV1 is < 50% of predicted normal.
-
Patients must not have moderate or severe persistent asthma within the past 2 years and must not have currently uncontrolled asthma of any classification.
-
Patients must not have had prior autograft or allograft, or prior organ transplant requiring immunosuppressive therapy.
-
Patients must not have known allergy to any of the study drugs.
-
Patients with uncontrolled bacterial, viral or fungal infections (currently taking medication and with progression or no clinical improvement) at time of enrollment are not eligible.
-
Patients must not have known central nervous system (CNS) involvement with multiple myeloma, defined as CSF positivity for plasma cells at any time or a parenchymal CNS plasmacytoma at time of enrollment. Lumbar puncture is not required.
-
Patients must not be seropositive for hepatitis C (except in the setting of sustained virologic response, defined as undetectable viral load at least 12 weeks after completion of antiviral therapy). HCV testing is only required if clinically indicated or if the patient has a history of HCV.
-
No other prior malignancy is allowed except for the following: adequately treated basal cell or squamous cell skin cancer, in situ cervical cancer, adequately treated Stage I or II cancer from which the patient is currently in complete remission, or any other cancer from which the patient has been disease free for three years.
-
Patients must not have any uncontrolled intercurrent illness including (not limited to): Symptomatic CHF (NYHA III/IV), unstable angina pectoris or coronary angioplasty, or stenting within 6 months prior to registration, Unstable cardiac arrhythmia (ongoing cardiac dysrhythmias of NCI CTCAE v5.0 Grade >/= 2), intra-cardiac defibrillators, known cardiac metastases, or abnormal cardiac valve morphology (>/= Grade 3), or known psychiatric illness that would limit study compliance.
Registration Step 2 - First Randomization (Post-ASCT, Pre-Maintenance)
Inclusion Criteria:
-
Patients must have completed ASCT within 180 days prior to registering to Step 2.
-
Patients must have one of the following performed within 60 days prior to registration for disease assessment: diagnostic quality skeletal survey, whole body CT scan, MRI, or PET.
-
Patients must have Zubrod Performance Status </= 2
-
Patients must have adequate bone marrow function as evidenced by platelets >/= 75,000/mm3 and ANC >/= 1,000/mm3 within 28 days prior to first randomization:
-
Patients must have adequate hepatic function defined by the following within 28 days prior to first randomization:
-
Total bilirubin </=1.5 x IULN (institutional upper limit of the norm) AND AST and ALT </=3.0 x IULN
-
Patients must have evidence of adequate renal function, as defined by creatinine clearance (CrCl) >/= 30 mL/min., as measured by a 24-hour urine collection, or estimated by the Cockcroft and Gault formula, or have a serum creatinine < 2.5 mg/dL within 28 days prior to first randomization.
-
All ASCT-related toxicities must have recovered to </=Grade 1 (except for alopecia, fatigue and amenorrhea) prior to first randomization.
-
Mucositis and gastrointestinal symptoms must have resolved to </=Grade 1.
-
Females of childbearing potential (FCBP) must have a negative serum or urine pregnancy test with a sensitivity of at least 25 mIU/mL within 10-14 days prior to registration.
-
FCBP must agree to have a second pregnancy test within 24 hours prior to starting Cycle 1. Further, FCBP must either commit to continued abstinence from heterosexual intercourse or begin TWO acceptable methods of birth control: one highly effective method and one additional effective method AT THE SAME TIME, at least 28 days before starting lenalidomide. FCBP must also agree to ongoing pregnancy testing and must agree to not become pregnant for at least 3 months after the last dose of study treatment.
-
Men must agree to use a latex condom during sexual contact with a FCBP, even if they have had a successful vasectomy, during the study treatment and for 3 months after the last dose of study treatment.
-
Patients must be informed of the investigational nature of this study and must sign and give written informed consent in accordance with institutional and federal guidelines.
Exclusion Criteria:
-
Patients must not have received any other maintenance therapy post-ASCT and prior to Step 2 registration.
-
Patients must not have had progressive disease between induction and registration to Registration Step 2. (See Section 10.1b).
Registration Step 3 - Second Randomization (Post 24 Months Maintenance)
Inclusion Criteria:
-
Patients must have completed 24 cycles of protocol maintenance with either lenalidomide or lenalidomide + daratumumab/rHuPH20.
-
Patients must have 24-month MRD by NGS test results available and must be MRD negative. Patients whose PCR results are indeterminable will be considered to have positive results.
-
Patients must be in very good partial remission (VGPR) or better by IMWG response criteria (see Section 10.1b).
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
---|---|---|---|---|---|
1 | Anchorage Associates in Radiation Medicine | Anchorage | Alaska | United States | 98508 |
2 | Anchorage Radiation Therapy Center | Anchorage | Alaska | United States | 99504 |
3 | Alaska Breast Care and Surgery LLC | Anchorage | Alaska | United States | 99508 |
4 | Alaska Oncology and Hematology LLC | Anchorage | Alaska | United States | 99508 |
5 | Alaska Women's Cancer Care | Anchorage | Alaska | United States | 99508 |
6 | Anchorage Oncology Centre | Anchorage | Alaska | United States | 99508 |
7 | Katmai Oncology Group | Anchorage | Alaska | United States | 99508 |
8 | Providence Alaska Medical Center | Anchorage | Alaska | United States | 99508 |
9 | Cancer Center at Saint Joseph's | Phoenix | Arizona | United States | 85004 |
10 | University of Arizona Cancer Center-Orange Grove Campus | Tucson | Arizona | United States | 85704 |
11 | Banner University Medical Center - Tucson | Tucson | Arizona | United States | 85719 |
12 | University of Arizona Cancer Center-North Campus | Tucson | Arizona | United States | 85719 |
13 | Mercy Hospital Fort Smith | Fort Smith | Arkansas | United States | 72903 |
14 | CHI Saint Vincent Cancer Center Hot Springs | Hot Springs | Arkansas | United States | 71913 |
15 | University of Arkansas for Medical Sciences | Little Rock | Arkansas | United States | 72205 |
16 | Kaiser Permanente-Deer Valley Medical Center | Antioch | California | United States | 94531 |
17 | Mission Hope Medical Oncology - Arroyo Grande | Arroyo Grande | California | United States | 93420 |
18 | Providence Saint Joseph Medical Center/Disney Family Cancer Center | Burbank | California | United States | 91505 |
19 | City of Hope Comprehensive Cancer Center | Duarte | California | United States | 91010 |
20 | Epic Care-Dublin | Dublin | California | United States | 94568 |
21 | Kaiser Permanente Dublin | Dublin | California | United States | 94568 |
22 | Bay Area Breast Surgeons Inc | Emeryville | California | United States | 94608 |
23 | Epic Care Partners in Cancer Care | Emeryville | California | United States | 94608 |
24 | Kaiser Permanente-Fremont | Fremont | California | United States | 94538 |
25 | Fresno Cancer Center | Fresno | California | United States | 93720 |
26 | Kaiser Permanente-Fresno | Fresno | California | United States | 93720 |
27 | Cedars Sinai Medical Center | Los Angeles | California | United States | 90048 |
28 | Contra Costa Regional Medical Center | Martinez | California | United States | 94553-3156 |
29 | Fremont - Rideout Cancer Center | Marysville | California | United States | 95901 |
30 | Kaiser Permanente-Modesto | Modesto | California | United States | 95356 |
31 | Alta Bates Summit Medical Center - Summit Campus | Oakland | California | United States | 94609 |
32 | Bay Area Tumor Institute | Oakland | California | United States | 94609 |
33 | Kaiser Permanente Oakland-Broadway | Oakland | California | United States | 94611 |
34 | Kaiser Permanente-Oakland | Oakland | California | United States | 94611 |
35 | UC Irvine Health/Chao Family Comprehensive Cancer Center | Orange | California | United States | 92868 |
36 | Desert Regional Medical Center | Palm Springs | California | United States | 92262 |
37 | Kaiser Permanente-Rancho Cordova Cancer Center | Rancho Cordova | California | United States | 95670 |
38 | Kaiser Permanente- Marshall Medical Offices | Redwood City | California | United States | 94063 |
39 | Kaiser Permanente-Redwood City | Redwood City | California | United States | 94063 |
40 | Kaiser Permanente-Richmond | Richmond | California | United States | 94801 |
41 | Rohnert Park Cancer Center | Rohnert Park | California | United States | 94928 |
42 | Kaiser Permanente-Roseville | Roseville | California | United States | 95661 |
43 | The Permanente Medical Group-Roseville Radiation Oncology | Roseville | California | United States | 95678 |
44 | Kaiser Permanente Downtown Commons | Sacramento | California | United States | 95814 |
45 | University of California Davis Comprehensive Cancer Center | Sacramento | California | United States | 95817 |
46 | Kaiser Permanente-South Sacramento | Sacramento | California | United States | 95823 |
47 | South Sacramento Cancer Center | Sacramento | California | United States | 95823 |
48 | Naval Medical Center -San Diego | San Diego | California | United States | 92134 |
49 | Kaiser Permanente-San Francisco | San Francisco | California | United States | 94115 |
50 | Kaiser Permanente-Santa Teresa-San Jose | San Jose | California | United States | 95119 |
51 | Kaiser Permanente San Leandro | San Leandro | California | United States | 94577 |
52 | Pacific Central Coast Health Center-San Luis Obispo | San Luis Obispo | California | United States | 93401 |
53 | Kaiser San Rafael-Gallinas | San Rafael | California | United States | 94903 |
54 | Kaiser Permanente Medical Center - Santa Clara | Santa Clara | California | United States | 95051 |
55 | Mission Hope Medical Oncology - Santa Maria | Santa Maria | California | United States | 93444 |
56 | Kaiser Permanente-Santa Rosa | Santa Rosa | California | United States | 95403 |
57 | Kaiser Permanente Cancer Treatment Center | South San Francisco | California | United States | 94080 |
58 | Kaiser Permanente-South San Francisco | South San Francisco | California | United States | 94080 |
59 | Kaiser Permanente-Stockton | Stockton | California | United States | 95210 |
60 | Gene Upshaw Memorial Tahoe Forest Cancer Center | Truckee | California | United States | 96161 |
61 | Kaiser Permanente Medical Center-Vacaville | Vacaville | California | United States | 95688 |
62 | Kaiser Permanente-Vallejo | Vallejo | California | United States | 94589 |
63 | Kaiser Permanente-Walnut Creek | Walnut Creek | California | United States | 94596 |
64 | Epic Care Cyberknife Center | Walnut Creek | California | United States | 94597 |
65 | Rocky Mountain Regional VA Medical Center | Aurora | Colorado | United States | 80045 |
66 | Penrose-Saint Francis Healthcare | Colorado Springs | Colorado | United States | 80907 |
67 | Rocky Mountain Cancer Centers-Penrose | Colorado Springs | Colorado | United States | 80907 |
68 | Saint Francis Cancer Center | Colorado Springs | Colorado | United States | 80923 |
69 | Kaiser Permanente-Franklin | Denver | Colorado | United States | 80205 |
70 | Porter Adventist Hospital | Denver | Colorado | United States | 80210 |
71 | Mercy Medical Center | Durango | Colorado | United States | 81301 |
72 | Southwest Oncology PC | Durango | Colorado | United States | 81301 |
73 | Kaiser Permanente-Rock Creek | Lafayette | Colorado | United States | 80026 |
74 | Saint Anthony Hospital | Lakewood | Colorado | United States | 80228 |
75 | Littleton Adventist Hospital | Littleton | Colorado | United States | 80122 |
76 | Kaiser Permanente-Lone Tree | Lone Tree | Colorado | United States | 80124 |
77 | Longmont United Hospital | Longmont | Colorado | United States | 80501 |
78 | Rocky Mountain Cancer Centers-Longmont | Longmont | Colorado | United States | 80501 |
79 | Parker Adventist Hospital | Parker | Colorado | United States | 80138 |
80 | Saint Mary Corwin Medical Center | Pueblo | Colorado | United States | 81004 |
81 | Beebe South Coastal Health Campus | Frankford | Delaware | United States | 19945 |
82 | Beebe Medical Center | Lewes | Delaware | United States | 19958 |
83 | Delaware Clinical and Laboratory Physicians PA | Newark | Delaware | United States | 19713 |
84 | Helen F Graham Cancer Center | Newark | Delaware | United States | 19713 |
85 | Medical Oncology Hematology Consultants PA | Newark | Delaware | United States | 19713 |
86 | Christiana Care Health System-Christiana Hospital | Newark | Delaware | United States | 19718 |
87 | Beebe Health Campus | Rehoboth Beach | Delaware | United States | 19971 |
88 | TidalHealth Nanticoke / Allen Cancer Center | Seaford | Delaware | United States | 19973 |
89 | Christiana Care Health System-Wilmington Hospital | Wilmington | Delaware | United States | 19801 |
90 | AdventHealth Altamonte | Altamonte Springs | Florida | United States | 32701 |
91 | AdventHealth Celebration | Celebration | Florida | United States | 34747 |
92 | UM Sylvester Comprehensive Cancer Center at Coral Gables | Coral Gables | Florida | United States | 33146 |
93 | UM Sylvester Comprehensive Cancer Center at Deerfield Beach | Deerfield Beach | Florida | United States | 33442 |
94 | Regional Cancer Center-Lee Memorial Health System | Fort Myers | Florida | United States | 33905 |
95 | University of Florida Health Science Center - Gainesville | Gainesville | Florida | United States | 32610 |
96 | UM Sylvester Comprehensive Cancer Center at Hollywood | Hollywood | Florida | United States | 33021 |
97 | AdventHealth Kissimmee | Kissimmee | Florida | United States | 34744 |
98 | University of Miami Miller School of Medicine-Sylvester Cancer Center | Miami | Florida | United States | 33136 |
99 | UM Sylvester Comprehensive Cancer Center at Kendall | Miami | Florida | United States | 33176 |
100 | AdventHealth Medical Group Urology at Orlando | Orlando | Florida | United States | 32803 |
101 | AdventHealth Orlando | Orlando | Florida | United States | 32803 |
102 | Orlando Health Cancer Institute | Orlando | Florida | United States | 32806 |
103 | AdventHealth East Orlando | Orlando | Florida | United States | 32822 |
104 | UM Sylvester Comprehensive Cancer Center at Plantation | Plantation | Florida | United States | 33324 |
105 | Moffitt Cancer Center-International Plaza | Tampa | Florida | United States | 33607 |
106 | Moffitt Cancer Center - McKinley Campus | Tampa | Florida | United States | 33612 |
107 | Moffitt Cancer Center | Tampa | Florida | United States | 33612 |
108 | AdventHealth Winter Park | Winter Park | Florida | United States | 32792 |
109 | Northside Hospital | Atlanta | Georgia | United States | 30342 |
110 | Hawaii Cancer Care - Savio | 'Aiea | Hawaii | United States | 96701 |
111 | Pali Momi Medical Center | 'Aiea | Hawaii | United States | 96701 |
112 | Queen's Cancer Center - Pearlridge | 'Aiea | Hawaii | United States | 96701 |
113 | The Cancer Center of Hawaii-Pali Momi | 'Aiea | Hawaii | United States | 96701 |
114 | Island Urology-Hilo | Hilo | Hawaii | United States | 96720 |
115 | Hawaii Cancer Care Inc - Waterfront Plaza | Honolulu | Hawaii | United States | 96813 |
116 | Island Urology | Honolulu | Hawaii | United States | 96813 |
117 | Queen's Cancer Cenrer - POB I | Honolulu | Hawaii | United States | 96813 |
118 | Queen's Medical Center | Honolulu | Hawaii | United States | 96813 |
119 | Straub Clinic and Hospital | Honolulu | Hawaii | United States | 96813 |
120 | University of Hawaii Cancer Center | Honolulu | Hawaii | United States | 96813 |
121 | Hawaii Cancer Care Inc-Liliha | Honolulu | Hawaii | United States | 96817 |
122 | Kuakini Medical Center | Honolulu | Hawaii | United States | 96817 |
123 | Queen's Cancer Center - Kuakini | Honolulu | Hawaii | United States | 96817 |
124 | The Cancer Center of Hawaii-Liliha | Honolulu | Hawaii | United States | 96817 |
125 | Kaiser Permanente Moanalua Medical Center | Honolulu | Hawaii | United States | 96819 |
126 | Kapiolani Medical Center for Women and Children | Honolulu | Hawaii | United States | 96826 |
127 | Wilcox Memorial Hospital and Kauai Medical Clinic | Lihue | Hawaii | United States | 96766 |
128 | Saint Alphonsus Cancer Care Center-Boise | Boise | Idaho | United States | 83706 |
129 | Saint Luke's Cancer Institute - Boise | Boise | Idaho | United States | 83712 |
130 | Saint Alphonsus Cancer Care Center-Caldwell | Caldwell | Idaho | United States | 83605 |
131 | Kootenai Health - Coeur d'Alene | Coeur d'Alene | Idaho | United States | 83814 |
132 | Walter Knox Memorial Hospital | Emmett | Idaho | United States | 83617 |
133 | Saint Luke's Cancer Institute - Fruitland | Fruitland | Idaho | United States | 83619 |
134 | Idaho Urologic Institute-Meridian | Meridian | Idaho | United States | 83642 |
135 | Saint Luke's Cancer Institute - Meridian | Meridian | Idaho | United States | 83642 |
136 | Saint Alphonsus Medical Center-Nampa | Nampa | Idaho | United States | 83686 |
137 | Saint Luke's Cancer Institute - Nampa | Nampa | Idaho | United States | 83686 |
138 | Kootenai Clinic Cancer Services - Post Falls | Post Falls | Idaho | United States | 83854 |
139 | Kootenai Cancer Clinic | Sandpoint | Idaho | United States | 83864 |
140 | Saint Luke's Cancer Institute - Twin Falls | Twin Falls | Idaho | United States | 83301 |
141 | Saint Anthony's Health | Alton | Illinois | United States | 62002 |
142 | Illinois CancerCare-Bloomington | Bloomington | Illinois | United States | 61704 |
143 | Loyola Center for Health at Burr Ridge | Burr Ridge | Illinois | United States | 60527 |
144 | Illinois CancerCare-Canton | Canton | Illinois | United States | 61520 |
145 | Memorial Hospital of Carbondale | Carbondale | Illinois | United States | 62902 |
146 | SIH Cancer Institute | Carterville | Illinois | United States | 62918 |
147 | Illinois CancerCare-Carthage | Carthage | Illinois | United States | 62321 |
148 | Centralia Oncology Clinic | Centralia | Illinois | United States | 62801 |
149 | University of Illinois | Chicago | Illinois | United States | 60612 |
150 | Cancer Care Specialists of Illinois - Decatur | Decatur | Illinois | United States | 62526 |
151 | Decatur Memorial Hospital | Decatur | Illinois | United States | 62526 |
152 | Illinois CancerCare-Dixon | Dixon | Illinois | United States | 61021 |
153 | Crossroads Cancer Center | Effingham | Illinois | United States | 62401 |
154 | Illinois CancerCare-Eureka | Eureka | Illinois | United States | 61530 |
155 | Illinois CancerCare-Galesburg | Galesburg | Illinois | United States | 61401 |
156 | Western Illinois Cancer Treatment Center | Galesburg | Illinois | United States | 61401 |
157 | Loyola Medicine Homer Glen | Homer Glen | Illinois | United States | 60491 |
158 | Illinois CancerCare-Kewanee Clinic | Kewanee | Illinois | United States | 61443 |
159 | Illinois CancerCare-Macomb | Macomb | Illinois | United States | 61455 |
160 | Loyola University Medical Center | Maywood | Illinois | United States | 60153 |
161 | Marjorie Weinberg Cancer Center at Loyola-Gottlieb | Melrose Park | Illinois | United States | 60160 |
162 | Good Samaritan Regional Health Center | Mount Vernon | Illinois | United States | 62864 |
163 | Cancer Care Center of O'Fallon | O'Fallon | Illinois | United States | 62269 |
164 | Illinois CancerCare-Ottawa Clinic | Ottawa | Illinois | United States | 61350 |
165 | Illinois CancerCare-Pekin | Pekin | Illinois | United States | 61554 |
166 | Illinois CancerCare-Peoria | Peoria | Illinois | United States | 61615 |
167 | Methodist Medical Center of Illinois | Peoria | Illinois | United States | 61636 |
168 | Illinois CancerCare-Peru | Peru | Illinois | United States | 61354 |
169 | Valley Radiation Oncology | Peru | Illinois | United States | 61354 |
170 | Illinois CancerCare-Princeton | Princeton | Illinois | United States | 61356 |
171 | Southern Illinois University School of Medicine | Springfield | Illinois | United States | 62702 |
172 | Springfield Clinic | Springfield | Illinois | United States | 62702 |
173 | Memorial Medical Center | Springfield | Illinois | United States | 62781 |
174 | Southwest Illinois Health Services LLP | Swansea | Illinois | United States | 62226 |
175 | Illinois CancerCare - Washington | Washington | Illinois | United States | 61571 |
176 | Indiana University/Melvin and Bren Simon Cancer Center | Indianapolis | Indiana | United States | 46202 |
177 | Community Cancer Center East | Indianapolis | Indiana | United States | 46219 |
178 | Community Cancer Center South | Indianapolis | Indiana | United States | 46227 |
179 | Community Cancer Center North | Indianapolis | Indiana | United States | 46256 |
180 | Springmill Medical Center | Indianapolis | Indiana | United States | 46290 |
181 | Community Howard Regional Health | Kokomo | Indiana | United States | 46904 |
182 | Reid Health | Richmond | Indiana | United States | 47374 |
183 | Mary Greeley Medical Center | Ames | Iowa | United States | 50010 |
184 | McFarland Clinic PC - Ames | Ames | Iowa | United States | 50010 |
185 | University of Iowa Healthcare Cancer Services Quad Cities | Bettendorf | Iowa | United States | 52722 |
186 | McFarland Clinic PC-Boone | Boone | Iowa | United States | 50036 |
187 | Saint Anthony Regional Hospital | Carroll | Iowa | United States | 51401 |
188 | Medical Oncology and Hematology Associates-West Des Moines | Clive | Iowa | United States | 50325 |
189 | Mercy Cancer Center-West Lakes | Clive | Iowa | United States | 50325 |
190 | Alegent Health Mercy Hospital | Council Bluffs | Iowa | United States | 51503 |
191 | Greater Regional Medical Center | Creston | Iowa | United States | 50801 |
192 | Iowa Methodist Medical Center | Des Moines | Iowa | United States | 50309 |
193 | Medical Oncology and Hematology Associates-Des Moines | Des Moines | Iowa | United States | 50309 |
194 | Broadlawns Medical Center | Des Moines | Iowa | United States | 50314 |
195 | Medical Oncology and Hematology Associates-Laurel | Des Moines | Iowa | United States | 50314 |
196 | Mercy Medical Center - Des Moines | Des Moines | Iowa | United States | 50314 |
197 | Iowa Lutheran Hospital | Des Moines | Iowa | United States | 50316 |
198 | McFarland Clinic PC-Trinity Cancer Center | Fort Dodge | Iowa | United States | 50501 |
199 | Trinity Regional Medical Center | Fort Dodge | Iowa | United States | 50501 |
200 | University of Iowa/Holden Comprehensive Cancer Center | Iowa City | Iowa | United States | 52242 |
201 | McFarland Clinic PC-Jefferson | Jefferson | Iowa | United States | 50129 |
202 | McFarland Clinic PC-Marshalltown | Marshalltown | Iowa | United States | 50158 |
203 | Methodist West Hospital | West Des Moines | Iowa | United States | 50266-7700 |
204 | Mercy Medical Center-West Lakes | West Des Moines | Iowa | United States | 50266 |
205 | Central Care Cancer Center - Garden City | Garden City | Kansas | United States | 67846 |
206 | Central Care Cancer Center - Great Bend | Great Bend | Kansas | United States | 67530 |
207 | University of Kansas Cancer Center-West | Kansas City | Kansas | United States | 66112 |
208 | University of Kansas Cancer Center | Kansas City | Kansas | United States | 66160 |
209 | University of Kansas Cancer Center-Overland Park | Overland Park | Kansas | United States | 66210 |
210 | University of Kansas Hospital-Westwood Cancer Center | Westwood | Kansas | United States | 66205 |
211 | Flaget Memorial Hospital | Bardstown | Kentucky | United States | 40004 |
212 | Commonwealth Cancer Center-Corbin | Corbin | Kentucky | United States | 40701 |
213 | Saint Joseph Radiation Oncology Resource Center | Lexington | Kentucky | United States | 40504 |
214 | Saint Joseph Hospital East | Lexington | Kentucky | United States | 40509 |
215 | University of Kentucky/Markey Cancer Center | Lexington | Kentucky | United States | 40536 |
216 | Saint Joseph London | London | Kentucky | United States | 40741 |
217 | Jewish Hospital | Louisville | Kentucky | United States | 40202 |
218 | The James Graham Brown Cancer Center at University of Louisville | Louisville | Kentucky | United States | 40202 |
219 | Saints Mary and Elizabeth Hospital | Louisville | Kentucky | United States | 40215 |
220 | Jewish Hospital Medical Center Northeast | Louisville | Kentucky | United States | 40245 |
221 | Jewish Hospital Medical Center South | Shepherdsville | Kentucky | United States | 40165 |
222 | Hematology/Oncology Clinic PLLC | Baton Rouge | Louisiana | United States | 70809 |
223 | Ochsner LSU Health Monroe Medical Center | Monroe | Louisiana | United States | 71202 |
224 | Louisiana State University Health Science Center | New Orleans | Louisiana | United States | 70112 |
225 | Tulane University Health Sciences Center | New Orleans | Louisiana | United States | 70112 |
226 | LSU Health Sciences Center at Shreveport | Shreveport | Louisiana | United States | 71103 |
227 | Eastern Maine Medical Center | Bangor | Maine | United States | 04401 |
228 | Lafayette Family Cancer Center-EMMC | Brewer | Maine | United States | 04412 |
229 | Walter Reed National Military Medical Center | Bethesda | Maryland | United States | 20889-5600 |
230 | Boston Medical Center | Boston | Massachusetts | United States | 02118 |
231 | Lahey Hospital and Medical Center | Burlington | Massachusetts | United States | 01805 |
232 | Lahey Medical Center-Peabody | Peabody | Massachusetts | United States | 01960 |
233 | UMass Memorial Medical Center - University Campus | Worcester | Massachusetts | United States | 01655 |
234 | University of Michigan Comprehensive Cancer Center | Ann Arbor | Michigan | United States | 48109 |
235 | Bronson Battle Creek | Battle Creek | Michigan | United States | 49017 |
236 | McLaren Cancer Institute-Bay City | Bay City | Michigan | United States | 48706 |
237 | Henry Ford Cancer Institute-Downriver | Brownstown | Michigan | United States | 48183 |
238 | McLaren Cancer Institute-Clarkston | Clarkston | Michigan | United States | 48346 |
239 | Henry Ford Macomb Hospital-Clinton Township | Clinton Township | Michigan | United States | 48038 |
240 | Henry Ford Medical Center-Fairlane | Dearborn | Michigan | United States | 48126 |
241 | Wayne State University/Karmanos Cancer Institute | Detroit | Michigan | United States | 48201 |
242 | Henry Ford Hospital | Detroit | Michigan | United States | 48202 |
243 | Weisberg Cancer Treatment Center | Farmington Hills | Michigan | United States | 48334 |
244 | McLaren Cancer Institute-Flint | Flint | Michigan | United States | 48532 |
245 | Singh and Arora Hematology Oncology PC | Flint | Michigan | United States | 48532 |
246 | Helen DeVos Children's Hospital at Spectrum Health | Grand Rapids | Michigan | United States | 49503 |
247 | Mercy Health Saint Mary's | Grand Rapids | Michigan | United States | 49503 |
248 | Spectrum Health at Butterworth Campus | Grand Rapids | Michigan | United States | 49503 |
249 | Allegiance Health | Jackson | Michigan | United States | 49201 |
250 | Bronson Methodist Hospital | Kalamazoo | Michigan | United States | 49007 |
251 | West Michigan Cancer Center | Kalamazoo | Michigan | United States | 49007 |
252 | Ascension Borgess Cancer Center | Kalamazoo | Michigan | United States | 49009 |
253 | Borgess Medical Center | Kalamazoo | Michigan | United States | 49048 |
254 | McLaren-Greater Lansing | Lansing | Michigan | United States | 48910 |
255 | Mid-Michigan Physicians-Lansing | Lansing | Michigan | United States | 48912 |
256 | McLaren Cancer Institute-Lapeer Region | Lapeer | Michigan | United States | 48446 |
257 | McLaren Cancer Institute-Central Michigan | Mount Pleasant | Michigan | United States | 48858 |
258 | Mercy Health Mercy Campus | Muskegon | Michigan | United States | 49444 |
259 | Lakeland Hospital Niles | Niles | Michigan | United States | 49120 |
260 | Cancer and Hematology Centers of Western Michigan - Norton Shores | Norton Shores | Michigan | United States | 49444 |
261 | Ascension Providence Hospitals - Novi | Novi | Michigan | United States | 48374 |
262 | Henry Ford Medical Center-Columbus | Novi | Michigan | United States | 48377 |
263 | McLaren Cancer Institute-Northern Michigan | Petoskey | Michigan | United States | 49770 |
264 | McLaren-Port Huron | Port Huron | Michigan | United States | 48060 |
265 | Spectrum Health Reed City Hospital | Reed City | Michigan | United States | 49677 |
266 | Lakeland Medical Center Saint Joseph | Saint Joseph | Michigan | United States | 49085 |
267 | Marie Yeager Cancer Center | Saint Joseph | Michigan | United States | 49085 |
268 | Henry Ford Macomb Health Center - Shelby Township | Shelby | Michigan | United States | 48315 |
269 | Ascension Providence Hospitals - Southfield | Southfield | Michigan | United States | 48075 |
270 | Munson Medical Center | Traverse City | Michigan | United States | 49684 |
271 | Henry Ford West Bloomfield Hospital | West Bloomfield | Michigan | United States | 48322 |
272 | Metro Health Hospital | Wyoming | Michigan | United States | 49519 |
273 | Riverwood Healthcare Center | Aitkin | Minnesota | United States | 56431 |
274 | Sanford Joe Lueken Cancer Center | Bemidji | Minnesota | United States | 56601 |
275 | Essentia Health Saint Joseph's Medical Center | Brainerd | Minnesota | United States | 56401 |
276 | Fairview Ridges Hospital | Burnsville | Minnesota | United States | 55337 |
277 | Minnesota Oncology - Burnsville | Burnsville | Minnesota | United States | 55337 |
278 | Cambridge Medical Center | Cambridge | Minnesota | United States | 55008 |
279 | Mercy Hospital | Coon Rapids | Minnesota | United States | 55433 |
280 | Essentia Health - Deer River Clinic | Deer River | Minnesota | United States | 56636 |
281 | Essentia Health Saint Mary's - Detroit Lakes Clinic | Detroit Lakes | Minnesota | United States | 56501 |
282 | Essentia Health Cancer Center | Duluth | Minnesota | United States | 55805 |
283 | Essentia Health Saint Mary's Medical Center | Duluth | Minnesota | United States | 55805 |
284 | Miller-Dwan Hospital | Duluth | Minnesota | United States | 55805 |
285 | Fairview Southdale Hospital | Edina | Minnesota | United States | 55435 |
286 | Lake Region Healthcare Corporation-Cancer Care | Fergus Falls | Minnesota | United States | 56537 |
287 | Essentia Health - Fosston | Fosston | Minnesota | United States | 56542 |
288 | Unity Hospital | Fridley | Minnesota | United States | 55432 |
289 | Essentia Health Hibbing Clinic | Hibbing | Minnesota | United States | 55746 |
290 | Fairview Clinics and Surgery Center Maple Grove | Maple Grove | Minnesota | United States | 55369 |
291 | Minnesota Oncology Hematology PA-Maplewood | Maplewood | Minnesota | United States | 55109 |
292 | Saint John's Hospital - Healtheast | Maplewood | Minnesota | United States | 55109 |
293 | Abbott-Northwestern Hospital | Minneapolis | Minnesota | United States | 55407 |
294 | Hennepin County Medical Center | Minneapolis | Minnesota | United States | 55415 |
295 | Health Partners Inc | Minneapolis | Minnesota | United States | 55454 |
296 | University of Minnesota/Masonic Cancer Center | Minneapolis | Minnesota | United States | 55455 |
297 | Monticello Cancer Center | Monticello | Minnesota | United States | 55362 |
298 | New Ulm Medical Center | New Ulm | Minnesota | United States | 56073 |
299 | Essentia Health - Park Rapids | Park Rapids | Minnesota | United States | 56470 |
300 | Fairview Northland Medical Center | Princeton | Minnesota | United States | 55371 |
301 | North Memorial Medical Health Center | Robbinsdale | Minnesota | United States | 55422 |
302 | Mayo Clinic in Rochester | Rochester | Minnesota | United States | 55905 |
303 | Coborn Cancer Center at Saint Cloud Hospital | Saint Cloud | Minnesota | United States | 56303 |
304 | Park Nicollet Clinic - Saint Louis Park | Saint Louis Park | Minnesota | United States | 55416 |
305 | Regions Hospital | Saint Paul | Minnesota | United States | 55101 |
306 | United Hospital | Saint Paul | Minnesota | United States | 55102 |
307 | Essentia Health Sandstone | Sandstone | Minnesota | United States | 55072 |
308 | Saint Francis Regional Medical Center | Shakopee | Minnesota | United States | 55379 |
309 | Lakeview Hospital | Stillwater | Minnesota | United States | 55082 |
310 | Sanford Thief River Falls Medical Center | Thief River Falls | Minnesota | United States | 56701 |
311 | Essentia Health Virginia Clinic | Virginia | Minnesota | United States | 55792 |
312 | Ridgeview Medical Center | Waconia | Minnesota | United States | 55387 |
313 | Rice Memorial Hospital | Willmar | Minnesota | United States | 56201 |
314 | Minnesota Oncology Hematology PA-Woodbury | Woodbury | Minnesota | United States | 55125 |
315 | Fairview Lakes Medical Center | Wyoming | Minnesota | United States | 55092 |
316 | Gulfport Memorial Hospital | Gulfport | Mississippi | United States | 39502 |
317 | Saint Louis Cancer and Breast Institute-Ballwin | Ballwin | Missouri | United States | 63011 |
318 | Central Care Cancer Center - Bolivar | Bolivar | Missouri | United States | 65613 |
319 | Parkland Health Center-Bonne Terre | Bonne Terre | Missouri | United States | 63628 |
320 | Cox Cancer Center Branson | Branson | Missouri | United States | 65616 |
321 | Saint Francis Medical Center | Cape Girardeau | Missouri | United States | 63703 |
322 | Southeast Cancer Center | Cape Girardeau | Missouri | United States | 63703 |
323 | Siteman Cancer Center at West County Hospital | Creve Coeur | Missouri | United States | 63141 |
324 | Parkland Health Center - Farmington | Farmington | Missouri | United States | 63640 |
325 | Capital Region Southwest Campus | Jefferson City | Missouri | United States | 65109 |
326 | Freeman Health System | Joplin | Missouri | United States | 64804 |
327 | Mercy Hospital Joplin | Joplin | Missouri | United States | 64804 |
328 | University of Kansas Cancer Center - North | Kansas City | Missouri | United States | 64154 |
329 | University of Kansas Cancer Center - Lee's Summit | Lee's Summit | Missouri | United States | 64064 |
330 | University of Kansas Cancer Center at North Kansas City Hospital | North Kansas City | Missouri | United States | 64116 |
331 | Delbert Day Cancer Institute at PCRMC | Rolla | Missouri | United States | 65401 |
332 | Mercy Clinic-Rolla-Cancer and Hematology | Rolla | Missouri | United States | 65401 |
333 | Heartland Regional Medical Center | Saint Joseph | Missouri | United States | 64506 |
334 | Saint Louis Cancer and Breast Institute-South City | Saint Louis | Missouri | United States | 63109 |
335 | Washington University School of Medicine | Saint Louis | Missouri | United States | 63110 |
336 | Mercy Hospital South | Saint Louis | Missouri | United States | 63128 |
337 | Siteman Cancer Center-South County | Saint Louis | Missouri | United States | 63129 |
338 | Missouri Baptist Medical Center | Saint Louis | Missouri | United States | 63131 |
339 | Siteman Cancer Center at Christian Hospital | Saint Louis | Missouri | United States | 63136 |
340 | Mercy Hospital Saint Louis | Saint Louis | Missouri | United States | 63141 |
341 | Siteman Cancer Center at Saint Peters Hospital | Saint Peters | Missouri | United States | 63376 |
342 | Sainte Genevieve County Memorial Hospital | Sainte Genevieve | Missouri | United States | 63670 |
343 | Mercy Hospital Springfield | Springfield | Missouri | United States | 65804 |
344 | CoxHealth South Hospital | Springfield | Missouri | United States | 65807 |
345 | Missouri Baptist Sullivan Hospital | Sullivan | Missouri | United States | 63080 |
346 | Missouri Baptist Outpatient Center-Sunset Hills | Sunset Hills | Missouri | United States | 63127 |
347 | Mercy Hospital Washington | Washington | Missouri | United States | 63090 |
348 | Community Hospital of Anaconda | Anaconda | Montana | United States | 59711 |
349 | Billings Clinic Cancer Center | Billings | Montana | United States | 59101 |
350 | Bozeman Deaconess Hospital | Bozeman | Montana | United States | 59715 |
351 | Benefis Healthcare- Sletten Cancer Institute | Great Falls | Montana | United States | 59405 |
352 | Great Falls Clinic | Great Falls | Montana | United States | 59405 |
353 | Kalispell Regional Medical Center | Kalispell | Montana | United States | 59901 |
354 | Saint Patrick Hospital - Community Hospital | Missoula | Montana | United States | 59802 |
355 | Community Medical Hospital | Missoula | Montana | United States | 59804 |
356 | CHI Health Saint Francis | Grand Island | Nebraska | United States | 68803 |
357 | CHI Health Good Samaritan | Kearney | Nebraska | United States | 68847 |
358 | Saint Elizabeth Regional Medical Center | Lincoln | Nebraska | United States | 68510 |
359 | Nebraska Methodist Hospital | Omaha | Nebraska | United States | 68114 |
360 | Alegent Health Immanuel Medical Center | Omaha | Nebraska | United States | 68122 |
361 | Alegent Health Bergan Mercy Medical Center | Omaha | Nebraska | United States | 68124 |
362 | Alegent Health Lakeside Hospital | Omaha | Nebraska | United States | 68130 |
363 | Creighton University Medical Center | Omaha | Nebraska | United States | 68131 |
364 | Midlands Community Hospital | Papillion | Nebraska | United States | 68046 |
365 | Cooper Hospital University Medical Center | Camden | New Jersey | United States | 08103 |
366 | The Valley Hospital-Luckow Pavilion | Paramus | New Jersey | United States | 07652 |
367 | Neurosurgeons of New Jersey-Ridgewood | Ridgewood | New Jersey | United States | 07450 |
368 | Valley Hospital | Ridgewood | New Jersey | United States | 07450 |
369 | Valley Health System-Hematology/Oncology | Westwood | New Jersey | United States | 07675 |
370 | University of New Mexico Cancer Center | Albuquerque | New Mexico | United States | 87102 |
371 | New Mexico Oncology Hematology Consultants | Albuquerque | New Mexico | United States | 87109 |
372 | NYP/Weill Cornell Medical Center | New York | New York | United States | 10065 |
373 | Rochester General Hospital | Rochester | New York | United States | 14621 |
374 | University of Rochester | Rochester | New York | United States | 14642 |
375 | Stony Brook University Medical Center | Stony Brook | New York | United States | 11794 |
376 | AdventHealth Infusion Center Asheville | Asheville | North Carolina | United States | 28803 |
377 | UNC Lineberger Comprehensive Cancer Center | Chapel Hill | North Carolina | United States | 27599 |
378 | Carolinas Medical Center/Levine Cancer Institute | Charlotte | North Carolina | United States | 28203 |
379 | Southeastern Medical Oncology Center-Clinton | Clinton | North Carolina | United States | 28328 |
380 | AdventHealth Infusion Center Haywood | Clyde | North Carolina | United States | 28721 |
381 | Atrium Health Cabarrus/LCI-Concord | Concord | North Carolina | United States | 28025 |
382 | Duke University Medical Center | Durham | North Carolina | United States | 27710 |
383 | Southeastern Medical Oncology Center-Goldsboro | Goldsboro | North Carolina | United States | 27534 |
384 | AdventHealth Hendersonville | Hendersonville | North Carolina | United States | 28792 |
385 | Southeastern Medical Oncology Center-Jacksonville | Jacksonville | North Carolina | United States | 28546 |
386 | Vidant Oncology-Kenansville | Kenansville | North Carolina | United States | 28349 |
387 | Vidant Oncology-Kinston | Kinston | North Carolina | United States | 28501 |
388 | FirstHealth of the Carolinas-Moore Regional Hospital | Pinehurst | North Carolina | United States | 28374 |
389 | Vidant Oncology-Richlands | Richlands | North Carolina | United States | 28574 |
390 | AdventHealth Infusion Center Weaverville | Weaverville | North Carolina | United States | 28787 |
391 | Wake Forest University Health Sciences | Winston-Salem | North Carolina | United States | 27157 |
392 | Sanford Bismarck Medical Center | Bismarck | North Dakota | United States | 58501 |
393 | Essentia Health Cancer Center-South University Clinic | Fargo | North Dakota | United States | 58103 |
394 | Sanford South University Medical Center | Fargo | North Dakota | United States | 58103 |
395 | Southpointe-Sanford Medical Center Fargo | Fargo | North Dakota | United States | 58103 |
396 | Sanford Medical Center Fargo | Fargo | North Dakota | United States | 58104 |
397 | Sanford Broadway Medical Center | Fargo | North Dakota | United States | 58122 |
398 | Sanford Roger Maris Cancer Center | Fargo | North Dakota | United States | 58122 |
399 | Essentia Health - Jamestown Clinic | Jamestown | North Dakota | United States | 58401 |
400 | Indu and Raj Soin Medical Center | Beavercreek | Ohio | United States | 45431 |
401 | Strecker Cancer Center-Belpre | Belpre | Ohio | United States | 45714 |
402 | Saint Elizabeth Boardman Hospital | Boardman | Ohio | United States | 44512 |
403 | Dayton Physicians LLC-Miami Valley South | Centerville | Ohio | United States | 45459 |
404 | Miami Valley Hospital South | Centerville | Ohio | United States | 45459 |
405 | Geauga Hospital | Chardon | Ohio | United States | 44024 |
406 | Adena Regional Medical Center | Chillicothe | Ohio | United States | 45601 |
407 | Good Samaritan Hospital - Cincinnati | Cincinnati | Ohio | United States | 45220 |
408 | Oncology Hematology Care Inc-Kenwood | Cincinnati | Ohio | United States | 45236 |
409 | Bethesda North Hospital | Cincinnati | Ohio | United States | 45242 |
410 | TriHealth Cancer Institute-Westside | Cincinnati | Ohio | United States | 45247 |
411 | TriHealth Cancer Institute-Anderson | Cincinnati | Ohio | United States | 45255 |
412 | Case Western Reserve University | Cleveland | Ohio | United States | 44106 |
413 | Cleveland Clinic Cancer Center/Fairview Hospital | Cleveland | Ohio | United States | 44111 |
414 | Cleveland Clinic Foundation | Cleveland | Ohio | United States | 44195 |
415 | Ohio State University Comprehensive Cancer Center | Columbus | Ohio | United States | 43210 |
416 | Mount Carmel East Hospital | Columbus | Ohio | United States | 43213 |
417 | Columbus Oncology and Hematology Associates Inc | Columbus | Ohio | United States | 43214 |
418 | Riverside Methodist Hospital | Columbus | Ohio | United States | 43214 |
419 | Grant Medical Center | Columbus | Ohio | United States | 43215 |
420 | The Mark H Zangmeister Center | Columbus | Ohio | United States | 43219 |
421 | Mount Carmel Health Center West | Columbus | Ohio | United States | 43222 |
422 | Doctors Hospital | Columbus | Ohio | United States | 43228 |
423 | Miami Valley Hospital | Dayton | Ohio | United States | 45409 |
424 | Dayton Physician LLC-Miami Valley Hospital North | Dayton | Ohio | United States | 45415 |
425 | Miami Valley Hospital North | Dayton | Ohio | United States | 45415 |
426 | Dayton Veterans Affairs Medical Center | Dayton | Ohio | United States | 45428 |
427 | Delaware Health Center-Grady Cancer Center | Delaware | Ohio | United States | 43015 |
428 | Grady Memorial Hospital | Delaware | Ohio | United States | 43015 |
429 | Dublin Methodist Hospital | Dublin | Ohio | United States | 43016 |
430 | Armes Family Cancer Center | Findlay | Ohio | United States | 45840 |
431 | Blanchard Valley Hospital | Findlay | Ohio | United States | 45840 |
432 | Orion Cancer Care | Findlay | Ohio | United States | 45840 |
433 | Atrium Medical Center-Middletown Regional Hospital | Franklin | Ohio | United States | 45005-1066 |
434 | Dayton Physicians LLC-Atrium | Franklin | Ohio | United States | 45005 |
435 | Central Ohio Breast and Endocrine Surgery | Gahanna | Ohio | United States | 43230 |
436 | Dayton Physicians LLC-Wayne | Greenville | Ohio | United States | 45331 |
437 | Wayne Hospital | Greenville | Ohio | United States | 45331 |
438 | Mount Carmel Grove City Hospital | Grove City | Ohio | United States | 43123 |
439 | Greater Dayton Cancer Center | Kettering | Ohio | United States | 45409 |
440 | First Dayton Cancer Care | Kettering | Ohio | United States | 45420 |
441 | Kettering Medical Center | Kettering | Ohio | United States | 45429 |
442 | Fairfield Medical Center | Lancaster | Ohio | United States | 43130 |
443 | Saint Rita's Medical Center | Lima | Ohio | United States | 45801 |
444 | OhioHealth Mansfield Hospital | Mansfield | Ohio | United States | 44903 |
445 | Cleveland Clinic Cancer Center Mansfield | Mansfield | Ohio | United States | 44906 |
446 | Marietta Memorial Hospital | Marietta | Ohio | United States | 45750 |
447 | OhioHealth Marion General Hospital | Marion | Ohio | United States | 43302 |
448 | Hillcrest Hospital Cancer Center | Mayfield Heights | Ohio | United States | 44124 |
449 | UH Seidman Cancer Center at Landerbrook Health Center | Mayfield Heights | Ohio | United States | 44124 |
450 | Knox Community Hospital | Mount Vernon | Ohio | United States | 43050 |
451 | Licking Memorial Hospital | Newark | Ohio | United States | 43055 |
452 | Newark Radiation Oncology | Newark | Ohio | United States | 43055 |
453 | Mercy Health Perrysburg Cancer Center | Perrysburg | Ohio | United States | 43551 |
454 | Southern Ohio Medical Center | Portsmouth | Ohio | United States | 45662 |
455 | North Coast Cancer Care | Sandusky | Ohio | United States | 44870 |
456 | UH Seidman Cancer Center at Firelands Regional Medical Center | Sandusky | Ohio | United States | 44870 |
457 | Springfield Regional Cancer Center | Springfield | Ohio | United States | 45504 |
458 | Springfield Regional Medical Center | Springfield | Ohio | United States | 45505 |
459 | Cleveland Clinic Cancer Center Strongsville | Strongsville | Ohio | United States | 44136 |
460 | Saint Vincent Mercy Medical Center | Toledo | Ohio | United States | 43608 |
461 | Mercy Health - Saint Anne Hospital | Toledo | Ohio | United States | 43623 |
462 | Dayton Physicians LLC-Upper Valley | Troy | Ohio | United States | 45373 |
463 | Upper Valley Medical Center | Troy | Ohio | United States | 45373 |
464 | South Pointe Hospital | Warrensville Heights | Ohio | United States | 44122 |
465 | Saint Joseph Warren Hospital | Warren | Ohio | United States | 44484 |
466 | Saint Ann's Hospital | Westerville | Ohio | United States | 43081 |
467 | UH Seidman Cancer Center at Saint John Medical Center | Westlake | Ohio | United States | 44145 |
468 | Cleveland Clinic Wooster Family Health and Surgery Center | Wooster | Ohio | United States | 44691 |
469 | Wright-Patterson Medical Center | Wright-Patterson Air Force Base | Ohio | United States | 45433 |
470 | Saint Elizabeth Youngstown Hospital | Youngstown | Ohio | United States | 44501 |
471 | Genesis Healthcare System Cancer Care Center | Zanesville | Ohio | United States | 43701 |
472 | Cancer Centers of Southwest Oklahoma Research | Lawton | Oklahoma | United States | 73505 |
473 | University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | United States | 73104 |
474 | Mercy Hospital Oklahoma City | Oklahoma City | Oklahoma | United States | 73120 |
475 | Oklahoma Cancer Specialists and Research Institute-Tulsa | Tulsa | Oklahoma | United States | 74146 |
476 | Saint Alphonsus Medical Center-Baker City | Baker City | Oregon | United States | 97814 |
477 | Saint Charles Health System | Bend | Oregon | United States | 97701 |
478 | Clackamas Radiation Oncology Center | Clackamas | Oregon | United States | 97015 |
479 | Providence Cancer Institute Clackamas Clinic | Clackamas | Oregon | United States | 97015 |
480 | Bay Area Hospital | Coos Bay | Oregon | United States | 97420 |
481 | Three Rivers Community Hospital | Grants Pass | Oregon | United States | 97527 |
482 | Rogue Valley Medical Center | Medford | Oregon | United States | 97504 |
483 | Providence Newberg Medical Center | Newberg | Oregon | United States | 97132 |
484 | Saint Alphonsus Medical Center-Ontario | Ontario | Oregon | United States | 97914 |
485 | Legacy Good Samaritan Hospital and Medical Center | Portland | Oregon | United States | 97210 |
486 | Providence Portland Medical Center | Portland | Oregon | United States | 97213 |
487 | Providence Saint Vincent Medical Center | Portland | Oregon | United States | 97225 |
488 | Kaiser Permanente Northwest | Portland | Oregon | United States | 97227 |
489 | Oregon Health and Science University | Portland | Oregon | United States | 97239 |
490 | Portland VA Medical Center | Portland | Oregon | United States | 97239 |
491 | Saint Charles Health System-Redmond | Redmond | Oregon | United States | 97756 |
492 | Christiana Care Health System-Concord Health Center | Chadds Ford | Pennsylvania | United States | 19317 |
493 | Geisinger Medical Center | Danville | Pennsylvania | United States | 17822 |
494 | Penn State Milton S Hershey Medical Center | Hershey | Pennsylvania | United States | 17033-0850 |
495 | University of Pennsylvania/Abramson Cancer Center | Philadelphia | Pennsylvania | United States | 19104 |
496 | Geisinger Wyoming Valley/Henry Cancer Center | Wilkes-Barre | Pennsylvania | United States | 18711 |
497 | Ralph H Johnson VA Medical Center | Charleston | South Carolina | United States | 29401 |
498 | Medical University of South Carolina | Charleston | South Carolina | United States | 29425 |
499 | McLeod Regional Medical Center | Florence | South Carolina | United States | 29506 |
500 | Saint Francis Hospital | Greenville | South Carolina | United States | 29601 |
501 | Saint Francis Cancer Center | Greenville | South Carolina | United States | 29607 |
502 | Avera Cancer Institute | Sioux Falls | South Dakota | United States | 57105 |
503 | Saint Joseph Regional Cancer Center | Bryan | Texas | United States | 77802 |
504 | M D Anderson Cancer Center | Houston | Texas | United States | 77030 |
505 | Huntsman Cancer Institute/University of Utah | Salt Lake City | Utah | United States | 84112 |
506 | Virginia Commonwealth University/Massey Cancer Center | Richmond | Virginia | United States | 23298 |
507 | Providence Regional Cancer System-Aberdeen | Aberdeen | Washington | United States | 98520 |
508 | PeaceHealth Saint Joseph Medical Center | Bellingham | Washington | United States | 98225 |
509 | Harrison HealthPartners Hematology and Oncology-Bremerton | Bremerton | Washington | United States | 98310 |
510 | Harrison Medical Center | Bremerton | Washington | United States | 98310 |
511 | Highline Medical Center-Main Campus | Burien | Washington | United States | 98166 |
512 | Providence Regional Cancer System-Centralia | Centralia | Washington | United States | 98531 |
513 | Swedish Cancer Institute-Edmonds | Edmonds | Washington | United States | 98026 |
514 | Saint Elizabeth Hospital | Enumclaw | Washington | United States | 98022 |
515 | Providence Regional Cancer Partnership | Everett | Washington | United States | 98201 |
516 | Saint Francis Hospital | Federal Way | Washington | United States | 98003 |
517 | Swedish Cancer Institute-Issaquah | Issaquah | Washington | United States | 98029 |
518 | Kadlec Clinic Hematology and Oncology | Kennewick | Washington | United States | 99336 |
519 | Providence Regional Cancer System-Lacey | Lacey | Washington | United States | 98503 |
520 | Saint Clare Hospital | Lakewood | Washington | United States | 98499 |
521 | PeaceHealth Saint John Medical Center | Longview | Washington | United States | 98632 |
522 | Harrison HealthPartners Hematology and Oncology-Poulsbo | Poulsbo | Washington | United States | 98370 |
523 | Pacific Gynecology Specialists | Seattle | Washington | United States | 98104 |
524 | Swedish Medical Center-Ballard Campus | Seattle | Washington | United States | 98107 |
525 | Swedish Medical Center-First Hill | Seattle | Washington | United States | 98122-4307 |
526 | Swedish Medical Center-Cherry Hill | Seattle | Washington | United States | 98122-5711 |
527 | PeaceHealth United General Medical Center | Sedro-Woolley | Washington | United States | 98284 |
528 | Providence Regional Cancer System-Shelton | Shelton | Washington | United States | 98584 |
529 | Franciscan Research Center-Northwest Medical Plaza | Tacoma | Washington | United States | 98405 |
530 | Northwest Medical Specialties PLLC | Tacoma | Washington | United States | 98405 |
531 | PeaceHealth Southwest Medical Center | Vancouver | Washington | United States | 98664 |
532 | Providence Saint Mary Regional Cancer Center | Walla Walla | Washington | United States | 99362 |
533 | Providence Regional Cancer System-Yelm | Yelm | Washington | United States | 98597 |
534 | United Hospital Center | Bridgeport | West Virginia | United States | 26330 |
535 | WVUH-Berkely Medical Center | Martinsburg | West Virginia | United States | 25401 |
536 | West Virginia University Healthcare | Morgantown | West Virginia | United States | 26506 |
537 | Camden Clark Medical Center | Parkersburg | West Virginia | United States | 26101 |
538 | ThedaCare Regional Cancer Center | Appleton | Wisconsin | United States | 54911 |
539 | Duluth Clinic Ashland | Ashland | Wisconsin | United States | 54806 |
540 | Northwest Wisconsin Cancer Center | Ashland | Wisconsin | United States | 54806 |
541 | Aurora Cancer Care-Southern Lakes VLCC | Burlington | Wisconsin | United States | 53105 |
542 | Aurora Saint Luke's South Shore | Cudahy | Wisconsin | United States | 53110 |
543 | Marshfield Medical Center-EC Cancer Center | Eau Claire | Wisconsin | United States | 54701 |
544 | Mayo Clinic Health System-Eau Claire Clinic | Eau Claire | Wisconsin | United States | 54701 |
545 | Mayo Clinic Health System Eau Claire Hospital-Luther Campus | Eau Claire | Wisconsin | United States | 54703 |
546 | Aurora Health Care Germantown Health Center | Germantown | Wisconsin | United States | 53022 |
547 | Aurora Cancer Care-Grafton | Grafton | Wisconsin | United States | 53024 |
548 | Bellin Memorial Hospital | Green Bay | Wisconsin | United States | 54301 |
549 | Saint Vincent Hospital Cancer Center Green Bay | Green Bay | Wisconsin | United States | 54301 |
550 | Saint Vincent Hospital Cancer Center at Saint Mary's | Green Bay | Wisconsin | United States | 54303 |
551 | Aurora BayCare Medical Center | Green Bay | Wisconsin | United States | 54311 |
552 | Aurora Cancer Care-Kenosha South | Kenosha | Wisconsin | United States | 53142 |
553 | Gundersen Lutheran Medical Center | La Crosse | Wisconsin | United States | 54601 |
554 | University of Wisconsin Hospital and Clinics | Madison | Wisconsin | United States | 53792 |
555 | Aurora Bay Area Medical Group-Marinette | Marinette | Wisconsin | United States | 54143 |
556 | Marshfield Medical Center-Marshfield | Marshfield | Wisconsin | United States | 54449 |
557 | Aurora Cancer Care-Milwaukee | Milwaukee | Wisconsin | United States | 53209 |
558 | Aurora Saint Luke's Medical Center | Milwaukee | Wisconsin | United States | 53215 |
559 | Medical College of Wisconsin | Milwaukee | Wisconsin | United States | 53226 |
560 | Aurora Sinai Medical Center | Milwaukee | Wisconsin | United States | 53233 |
561 | Marshfield Clinic-Minocqua Center | Minocqua | Wisconsin | United States | 54548 |
562 | ProHealth D N Greenwald Center | Mukwonago | Wisconsin | United States | 53149 |
563 | Froedtert and MCW Moorland Reserve Health Center | New Berlin | Wisconsin | United States | 53151 |
564 | Cancer Center of Western Wisconsin | New Richmond | Wisconsin | United States | 54017 |
565 | ProHealth Oconomowoc Memorial Hospital | Oconomowoc | Wisconsin | United States | 53066 |
566 | Saint Vincent Hospital Cancer Center at Oconto Falls | Oconto Falls | Wisconsin | United States | 54154 |
567 | Vince Lombardi Cancer Clinic - Oshkosh | Oshkosh | Wisconsin | United States | 54904 |
568 | Aurora Cancer Care-Racine | Racine | Wisconsin | United States | 53406 |
569 | Marshfield Medical Center-Rice Lake | Rice Lake | Wisconsin | United States | 54868 |
570 | Vince Lombardi Cancer Clinic-Sheboygan | Sheboygan | Wisconsin | United States | 53081 |
571 | Marshfield Clinic Stevens Point Center | Stevens Point | Wisconsin | United States | 54482 |
572 | Saint Vincent Hospital Cancer Center at Sturgeon Bay | Sturgeon Bay | Wisconsin | United States | 54235-1495 |
573 | Aurora Medical Center in Summit | Summit | Wisconsin | United States | 53066 |
574 | Vince Lombardi Cancer Clinic-Two Rivers | Two Rivers | Wisconsin | United States | 54241 |
575 | ProHealth Waukesha Memorial Hospital | Waukesha | Wisconsin | United States | 53188 |
576 | UW Cancer Center at ProHealth Care | Waukesha | Wisconsin | United States | 53188 |
577 | ThedaCare Cancer Care - Waupaca | Waupaca | Wisconsin | United States | 54981 |
578 | Aurora Cancer Care-Milwaukee West | Wauwatosa | Wisconsin | United States | 53226 |
579 | Aurora West Allis Medical Center | West Allis | Wisconsin | United States | 53227 |
580 | Marshfield Medical Center - Weston | Weston | Wisconsin | United States | 54476 |
581 | Billings Clinic-Cody | Cody | Wyoming | United States | 82414 |
582 | Welch Cancer Center | Sheridan | Wyoming | United States | 82801 |
Sponsors and Collaborators
- Southwest Oncology Group
- National Cancer Institute (NCI)
- Janssen, LP
- Adaptive
Investigators
- Principal Investigator: Amrita Krishnan, MD, FACP, City of Hope Medical Center
- Principal Investigator: Parameswaran Hari, MD, Medical College of Wisconsin
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- S1803
- U10CA180888
- NCI-2018-02465