Follow-up Study of the Effectiveness of Virtual Reality Therapy in MS Patients
Study Details
Study Description
Brief Summary
Different therapies can improve clinical and motor symptoms of multiple sclerosis (MS) similarly, but studies comparing the effects of different exercise therapies on clinical and motor outcomes are scant. We compared the effects of exergaming (EXE), balance (BAL), cycling (CYC), proprioceptive neuromuscular facilitation (PNF), and a standard care wait-listed control group (CON) on clinical and motor symptoms and quality of life (QoL) in people with MS (PwMS).
Methods: PwMS (n = 68, 90% female; age, 47.0 yr; Expanded Disability Status Scale score 5-6) were randomized into five groups. Before and after the interventions (five times a week for 5 wk), PwMS were tested for MS-related clinical and motor symptoms (Multiple Sclerosis Impact Scale-29 (MSIS-29), primary outcome), QoL (EuroQol Five Dimensions Questionnaire), symptoms of depression, gait and balance ability (Tinetti Assessment Tool), static and dynamic balance and fall risk (Berg Balance Scale), walking capacity (6-min walk test), and standing posturography on a force platform.
Patients were followed up for 2 years after 5 weeks of intensive care. Tests are performed every six months.
Condition or Disease | Intervention/Treatment | Phase |
---|---|---|
|
N/A |
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
---|---|
No Intervention: Controll No intervention |
|
Experimental: Training grp Neurorehabilitation 2 years long intervention, administered daily, targeted postural instability, balance and mobility using at-limit intensity sensorimotor and visuomotor agility training |
Other: Training groupe
Using virtual training
|
Experimental: PNF 2 years long, You have only treated patients with the PNF technique. |
Other: PNF
PNF technique was used
|
Experimental: Spinning group Patients developed endurance for 2 years. They worked using a spinning bike. |
Other: Spinning grp
They only worked with spinning bikes.
|
Experimental: Balance Neurorehabilitation 2 years long intervention, administered daily, targeted postural instability, balance |
Other: Balance
Balance development was done
|
Outcome Measures
Primary Outcome Measures
- Postural instability [2 years]
Body sway (mm) (Posturography test)
- EQ-5D quality of life [2 years]
EQ-5D (EQ-5D was first introduced in 1990 by the EuroQol Group, The EQ-5D questionnaire is made up for two components; health state description and evaluation)
- balance test [2 years]
Berg Balance test (The Berg Balance Scale (BBS) was developed to measure balance among older people with impairment in balance function by assessing the performance of functional tasks, 41-56 = low fall risk, 21-40 = medium fall risk, 0 -20 = high fall risk )
- mobility test [2 years]
Six minutes walk test (6MWT) (m) (The six-minute walk test (6MWT) measures the distance an individual is able to walk over a total of six minutes on a hard, flat surface. The goal is for the individual to walk as far as possible in six minutes. The individual is allowed to self-pace and rest as needed as they traverse back and forth along a marked walkway)
- depression scale [2 years]
Beck Depression scale (The Beck Depression Inventory (BDI) is a 21-item, self-report rating inventory that measures characteristic attitudes and symptoms of depression, 0-13: minimal depression, 14-19: mild depression, 20-28: moderate depression, 29-63: severe depression)
- MSIS-29 [2 years]
Multiple Sclerosis Questionnaire
Eligibility Criteria
Criteria
Inclusion Criteria:
-
Multiple Sclerosis
-
instability problem
Exclusion Criteria:
• Severe heart problems, severe demeanor, alcoholism, drug problems
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
---|---|---|---|---|---|
1 | Somogy Megyei Kaposi Mór Oktató Kórház | Kaposvár | Somogy | Hungary | 7400 |
Sponsors and Collaborators
- Somogy Megyei Kaposi Mór Teaching Hospital
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Additional Information:
Publications
None provided.- IKEB2020/08