Red Light Intervention for Myopia Prevention
Study Details
Study Description
Brief Summary
To explore the effectiveness of using low-intensity single-wavelength red light to prevent myopia in schoolchildren, and to provide a feasible scheme for reducing the incidence of myopia.
Condition or Disease | Intervention/Treatment | Phase |
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|
N/A |
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
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Experimental: Intervention Red light irradiation was conducted at school from Monday to Friday and at home everyday in summer and winter holiday twice a day for 3 minutes per time, with an interval of 4 hours |
Device: LLLT(Low Level Laser Therapy)
2 times a day, 3 minutes each time, with an interval of more than 4 hours. During the semester: From Monday to Friday, set up an intervention room in the school; For winter and summer vacation: everyday at home
|
No Intervention: Control No intervention |
Outcome Measures
Primary Outcome Measures
- One-year cumulative incidence of myopia (%) in the intervention group and the control group. [1 year]
Myopia is defined as the cycloplegic spherical equivalent of either eye ≤-0.5D
Secondary Outcome Measures
- The progress of spherical equivalent(SE,D) of children in intervention group and control group. [1 year]
The spherical equivalent(SE,D) will be measured by autorefractor(KR-8900, Topcon).
- The progress of axial length of children in intervention group and control group. [1 year]
The axial length will be measured using IOLMaster.
- The progress of choroidal thickness in children in pre-myopia state in intervention group and control group. [1 year]
The choroidal thickness will be measured using SS-OCT.
- The change of uncorrected visual acuity (UCVA) of children in intervention group and control group. [1 year]
The uncorrected visual acuity (UCVA) will be measured using a mounted and illuminated E chart of the Early Treatment Diabetic Retinopathy study (ETDRS) charts.
Eligibility Criteria
Criteria
Inclusion Criteria:
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Students of grade 1-4 in the participating schools;
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Students' eyes have no myopia, that is the cycloplegic spherical equivalent(SE)
-0.50D, and at least one eye accords with the pre-myopic state, that is -0.50D <cycloplegic SE≤0.50D;
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Students whose mother and/or father are in myopia status (SE < -3.0D for either of eyes);
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Students whose parents sign informed consent and agree to let their kids participate in baseline screen and follow-up examinations and surveys.
Exclusion Criteria:
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Students whose parents do not sign informed consent;
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Students who have strabismus and/or other binocular vision abnormality;
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Students who have other eye diseases and/or systematic diseases;
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Students who meet the standards with which investigators and study physicians think it is not appropriate to enroll.
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
---|---|---|---|---|---|
1 | Xiangui He | Shanghai | Shanghai | China | 200040 |
Sponsors and Collaborators
- Shanghai Eye Disease Prevention and Treatment Center
Investigators
- Study Director: Xiangui He, Shanghai Eye Disease Prevention and Treatment Center
Study Documents (Full-Text)
More Information
Publications
None provided.- SHYB2021001