Near Horizontal Heterophoria in Chinese Children
Study Details
Study Description
Brief Summary
This study aimed to assess the association of refraction and axial length with near-horizontal heterophoria in a large population-based study of school-aged Chinese children. The study makes a significant contribution to better know the etiology of myopia progression and ocular axial length development. Further, this study will be of interest to the readership of your journal because its noteworthy finding and which could contribute to guide recommendations for targeted interventions to slow myopia progression.
Condition or Disease | Intervention/Treatment | Phase |
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Detailed Description
Myopia is becoming a global public health burden which is believed to have a multifactorial etiology. The relationship between heterophoria and refraction remains controversial. We describe the association of refraction and axial length (AL) with heterophoria in a large population-based study of school-aged Chinese children. Eleven thousand thirteen elementary school children grades 1-6, were included in this school-based, cross-sectional study. Near phoria data was quantified by using Maddox rod test and prism at 33 cm. Children in each grade level were sorted into three groups based upon phoria: 1) those with more than six prism diopters (PD) exophoria, 2) those with zero to six PD exophoria, and 3) those with any amount of esophoria. Autorefraction was measured by autorefractor (Topcon KR8900, Japan) and AL was measured by Optical Biometer AL-Scan (Nidek AL-Scan, Japan). A generalized additive model (GAM) was applied with a Gaussian link to explore the association between the refractive error or axial length and heterophoria. An additional age-adjusted model was also employed for analysis.
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
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zero to six Exo
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Other: axial length and refractive error
Comparing the correlation between heterophoria and refraction, even after age adjustment.
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Outcome Measures
Primary Outcome Measures
- refractive error [change from baseline with EDTRS chart at 6 months]
Eligibility Criteria
Criteria
Inclusion Criteria:
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ages of 6 and 13 years
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Chinese school children
Exclusion Criteria:
- Subjects with eye diseases or strabismus
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
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1 | Tianjin Eye Hospital | Tianjin | China |
Sponsors and Collaborators
- Tianjin Eye Hospital
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
- Grzybowski A, Kanclerz P, Tsubota K, Lanca C, Saw SM. A review on the epidemiology of myopia in school children worldwide. BMC Ophthalmol. 2020 Jan 14;20(1):27. doi: 10.1186/s12886-019-1220-0. Review.
- Holden BA, Fricke TR, Wilson DA, Jong M, Naidoo KS, Sankaridurg P, Wong TY, Naduvilath TJ, Resnikoff S. Global Prevalence of Myopia and High Myopia and Temporal Trends from 2000 through 2050. Ophthalmology. 2016 May;123(5):1036-42. doi: 10.1016/j.ophtha.2016.01.006. Epub 2016 Feb 11. Review.
- 2021020