ROSE: Objective Systolic Function Recuperation Assessed by Echocardiography
Study Details
Study Description
Brief Summary
The purpose of this study is to evaluate left ventricular systolic ejection fraction and anterior or apical akinesis 1 month and 3 months after a myocardial infarction treated with primary PCI to determine whether improvement at 1 month differs from improvement at 3 months.
Condition or Disease | Intervention/Treatment | Phase |
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Study Design
Arms and Interventions
Arm | Intervention/Treatment |
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Echocardiography 1 month Patients will all have an echocardiography 1 month post myocardial infarction and 3 months post myocardial infarction |
Outcome Measures
Primary Outcome Measures
- Left ventricular ejection fraction recuperation 1 month post myocardial infarction [1 month post myocardial infarction]
Left ventricular ejection fraction recuperation 1 month post myocardial infarction as compared with the left ejection fraction 3 months post myocardial infarction
Secondary Outcome Measures
- Anterior and apical akinesis recuperation 1 month post myocardial infarction [1 month post myocardial infarction]
Anterior and apical akinesis recuperation 1 month post myocardial infarction as compared with 3 months post myocardial infarction
Eligibility Criteria
Criteria
Inclusion Criteria:
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Older than 18 years old
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ST elevation myocardial infarction treated with primary PCI
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Anterior or apical akinesis and left ventricular ejection fraction ≤ 45% on early echocardiography (48hours - 7 days post myocardial infarction)
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Initial ECG showing at least 1 mm ST elevation in 2 leads corresponding to the same vascular territory
Exclusion Criteria:
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Known left ventricular systolic dysfunction before myocardial infarction
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Left bundle branch block
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Vital prognosis less than 6 months
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Cardiogenic shock
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Rescue PCI
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Sub-optimal echocardiographic imaging (contrast use is allowed)
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Significant valvular heart disease (moderate or severe)
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Surgical revascularization
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Pregnancy or breastfeeding
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Incapacity to provide informed consent
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
---|---|---|---|---|---|
1 | Centre hospitalier universitaire de Sherbrooke | Sherbrooke | Quebec | Canada | J1H 5N4 |
Sponsors and Collaborators
- Paul Farand
Investigators
- Principal Investigator: Paul Farand, md, Centre de recherche du Centre hospitalier universitaire de Sherbrooke
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- 10-010