Observational Study About In-patients Admitted With Fever

Sponsor
Xiangya Hospital of Central South University (Other)
Overall Status
Recruiting
CT.gov ID
NCT05422651
Collaborator
(none)
500
1
50
10

Study Details

Study Description

Brief Summary

Fever is a common symptom in patients with infectious diseases. This study hopes to understand the epidemiological characteristics of patients hospitalized due to fever through observational research, including: clinical characteristics, etiology of fever and prognosis after treatment. So as to further search for biochemical or other serological indicators to predict the diagnosis and prognosis of infectious fever and non-infectious fever, and try to establish relevant prediction models.

Condition or Disease Intervention/Treatment Phase

    Detailed Description

    This study mainly prospectively analyze the clinical data of patients with fever with/without other symptoms admitted to the department of infectious diseases, Xiangya Hospital of Central South University, to analyze the epidemiological characteristics, diagnosis and prognosis of these patients. This is an observational study. All subjects will receive the currently recognized routine test of fever according to their disease and corresponding etiological treatment if needed. The researchers will collect various clinical examination indexes of the subjects in the process of diagnosis and treatment, including but not limited to white blood cells, C-reactive protein, Procalcitonin, ferritin, blood culture, therapeutic drugs, etc. Etiology and prognosis of patients will be recorded. Blood samples, urine and stool samples of all subjects will be taken after enrollment and stored for probably testing in the future. This study has no additional intervention and treatment for subjects. All subjects will sign informed consent.

    Study Design

    Study Type:
    Observational
    Anticipated Enrollment :
    500 participants
    Observational Model:
    Cohort
    Time Perspective:
    Prospective
    Official Title:
    Characteristic, Diagnosis and Prognosis of Patients Admitted With Fever in Department of Infectious Diseases
    Actual Study Start Date :
    Jun 1, 2022
    Anticipated Primary Completion Date :
    Aug 1, 2024
    Anticipated Study Completion Date :
    Aug 1, 2026

    Arms and Interventions

    Arm Intervention/Treatment
    patients with fever

    All subjects will receive the currently recognized routine test of fever according to their disease and corresponding etiological treatment if needed and no additional intervention and treatment will be added for subjects

    Outcome Measures

    Primary Outcome Measures

    1. Length of fever [1 month after admission]

      The interval between the onset of fever and the return of body temperature to normal after medical intervention or spontaneous remission

    Secondary Outcome Measures

    1. Fever associated mortality [3 months]

      mortality of patients due to conditions associated with fever

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    14 Years to 90 Years
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    No
    Inclusion Criteria:
    • all patients admitted to department of infectious diseases because of fever
    Exclusion Criteria:
    • patents who refuse to sign informed consent

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Department of Infectious Disease, Xiangya Hospital, Central South University Changsha Hunan China 410008

    Sponsors and Collaborators

    • Xiangya Hospital of Central South University

    Investigators

    • Principal Investigator: Yan Huang, Xiangya Hospital of Central South University

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    Huang Yan, Professor, Xiangya Hospital of Central South University
    ClinicalTrials.gov Identifier:
    NCT05422651
    Other Study ID Numbers:
    • Xiangya fever project
    First Posted:
    Jun 16, 2022
    Last Update Posted:
    Jun 29, 2022
    Last Verified:
    Jun 1, 2022
    Individual Participant Data (IPD) Sharing Statement:
    Undecided
    Plan to Share IPD:
    Undecided
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Additional relevant MeSH terms:

    Study Results

    No Results Posted as of Jun 29, 2022