OCTA and Retinal Angiomatous Proliferation
Study Details
Study Description
Brief Summary
To investigate, using optical coherence tomography angiography, the retinal vascular features in patients affected by RAP.
Condition or Disease | Intervention/Treatment | Phase |
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Detailed Description
Retinal vascular anomalous complex represents a distinct form of neovascularization in patients with age-related macular degeneration.
The study investigated the changes in retinal vascular network using optical coherence tomography angiography, a novel and non invasive diagnostic technique that allows to better understand the pathophysiologic mechanism of this neovascularization.
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
---|---|
Patients with RAP Patients with previous diagnosis of retinal angiomatous proliferation |
Diagnostic Test: optical coherence tomography angiography
optical coherence tomography aniography is a non-invasive, fast, diagnostic imaging technique that evaluates the retinal vascular network
|
Patients with reticular pseudodrusen Patients with previous diagnosis of reticular pseudodrusen |
Diagnostic Test: optical coherence tomography angiography
optical coherence tomography aniography is a non-invasive, fast, diagnostic imaging technique that evaluates the retinal vascular network
|
Control group Healthy eyes without actual and previous ocular diseases |
Diagnostic Test: optical coherence tomography angiography
optical coherence tomography aniography is a non-invasive, fast, diagnostic imaging technique that evaluates the retinal vascular network
|
Outcome Measures
Primary Outcome Measures
- The measurements of retinal vascular network in patients with age-related macular degeneration, using optical coherence tomography angiography, compared to controls [15 months]
The parameters analyzed by optical coherence tomography angiography were: vessel density of superficial capillary plexus and deep capillary plexus
Eligibility Criteria
Criteria
Inclusion Criteria:
-
age older than 65 years
-
diagnosis of retinal angiomatous proliferation and reticular pseudodrusen
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absence of previous ocular surgery, congenital eye disease, high myopia (>6 dioptres), actual or previous diagnosis of glaucoma, optic disc anomaly, macular or vitreoretinal diseases.
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absence of significant lens opacities, low-quality OCT-A images.
Exclusion Criteria:
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age older than 80 years
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absence of diagnosis of retinal angiomatous proliferation and reticular pseudodrusen
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presence of previous ocular surgery, congenital eye disease, high myopia (>6 dioptres), actual or previous diagnosis of glaucoma, optic disc anomaly, macular or vitreoretinal diseases.
-
presence of significant lens opacities, low-quality OCT-A images.
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
---|---|---|---|---|---|
1 | Federico II University | Naples | Napoli | Italy | 80131 |
Sponsors and Collaborators
- Federico II University
Investigators
- Principal Investigator: Gilda Cennamo, Federico II University
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- 2912/20