Oral Vitamin D Supplementation in Elderly Women
Study Details
Study Description
Brief Summary
The aim of this study is to compare oral vitamin D supplementation administered in two different ways, namely either twice a day (800IU/d, 292000IU/y) or three times a year (97333IU every 4 months, 292000IU/y) in elderly women in combination with daily supplementation of calcium 1 gram. We will 1)compare the blood concentrations of 25 OH vitamin D in the two treatment groups amd monitor if a sufficient and safe concentration of 25OH D in blood can be maintained with these two treatments.2) Find out seasonal variation in vitamin D concentrations in these treatments. 3) Find out safety of these treatments
Condition or Disease | Intervention/Treatment | Phase |
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|
N/A |
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
---|---|
Active Comparator: 1
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Dietary Supplement: vitamin D twice daily
Kalsipos-D, vitamin D3 400 ID/tbl, 2 tbl/day for one year
|
Experimental: 2
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Dietary Supplement: Vitamin D3 oil three times in a year
Vigantol oil , D3 20000IU/ml, 4.9 ml every four months for one year
|
Outcome Measures
Primary Outcome Measures
- Blood 25 OH D vitamin concentrations [8 times during the year]
Secondary Outcome Measures
- serum calcium, 24-hour calcium excretion in urine, creatinine clearance [8 times during the year]
Eligibility Criteria
Criteria
Inclusion Criteria:
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Females
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70-80 years
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Living in the community
Exclusion Criteria:
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Renal disease
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Diseases that contraindicate vitamin D supplementation
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Medications affecting bone
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Malignancy
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
---|---|---|---|---|---|
1 | Helsinki University Central Hospital, department of medicine, division of endocrinology | Helsinki | Finland | 00029 HUS |
Sponsors and Collaborators
- University of Helsinki
- Päivikki and Sakari Sohlberg Foundation, Finland
- Lilly Foundation
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- 77/2006