Permanent Occlusion of Uteine Arteies in Management of Abnormal Uterine Bleeding
Study Details
Study Description
Brief Summary
Prospective observational interventional study , The study done in two phases:
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Phase one from October 2011to May 2012 pilot study including twenty nine (29) premenopausal patients followed up for six months
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Phase two from October 2012 till May 2014. Including Eighty nine (89) premenopausal patients all of them needing to preserve their uteri.
Condition or Disease | Intervention/Treatment | Phase |
---|---|---|
|
Phase 1/Phase 2 |
Detailed Description
Abstract Objectives: To assess the effectiveness of permanent bilateral occlusion of uterine arteries in treatment of abnormal uterine bleeding.
Design: prospective observational study Setting: Done in Mansoura university hospital, department of Obstetrics and gynecology.
Patients and Methods: The study done in two phases:
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Phase one from October 2011to May 2012 pilot study including twenty nine (29) premenopausal patients followed up for six months
-
Phase two from October 2012 till May 2014. Including Eighty nine (89) premenopausal patients all of them needing to preserve their uteri.
Results: Results are hopeful and courageous in phase one as regards patients satisfaction, Quality of life and improvements of bleeding. Results of phase two will be implemented, analyzed and presented in tables. All data will be statistically analyzed and the results will be presented after completion of eighteen (18) months follow up to rule out any bias and/ or errors in the results.
Conclusion: permanent bilateral uterine arteries occlusion may be a good alternative to radical surgery in abnormal uterine bleeding.
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
---|---|
Other: BUAO The study done in two phases: Phase one from October 2011to May 2012 pilot study including twenty nine (29) premenopausal patients followed up for six months Phase two from October 2012 till May 2014. Including Eighty nine (89) premenopausal patients |
Procedure: bilateral permanent occlusion of uterine arteries
bilateral permanent Occlusion of uterine arteries through abdominal route
|
Outcome Measures
Primary Outcome Measures
- uterine bleeding [October 2011 till January 2016]
Secondary Outcome Measures
- patient satisfaction [october 2011 - may 2015]
- quality of life [october 2011 - may 2015]
Eligibility Criteria
Criteria
Inclusion Criteria:
- premenopausal with abnormal uterine bleeding and completed their families having normal endometrium (biopsy in preceding 6 months ) and may have uterine intramural myomas not exceeding 150 ml in volume and away from uterine cavity by at least 1cm and /or adenomyosis
Exclusion Criteria:
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patients wishing future fertility
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endometrial sampling not done or more than 6 months or myoma encroaching or distorting cavity or larger than 150 ml in volume
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
---|---|---|---|---|---|
1 | Mansoura Integrated fertility center | Mansoura | Dekahlia | Egypt |
Sponsors and Collaborators
- Mansoura Integrated Fertility Center
Investigators
- Principal Investigator: Adel S Helal, MD, Mansoura Integrated Fertility Center
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- Adelhelal