Effectiveness of IRK-19® on Body Weight Control
Study Details
Study Description
Brief Summary
This randomized, double-blind, placebo-controlled, and parallel clinical study aims to investigate the effectivness of a pumpkin seed extract (IRK-19®) on weight management.
Condition or Disease | Intervention/Treatment | Phase |
---|---|---|
|
N/A |
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
---|---|
Placebo Comparator: Placebo Placebo capsule |
Dietary Supplement: Pumpkin seed extract (IRK-19)
Placebo: Dietary fiber powder, two capsules/day (600 mg/day), continued use for 3 months Treatment: Pumpkin seed extract powder, two capsules/day (600 mg/day), continued use for 3 months
|
Experimental: Treatment IRK-19 capsule |
Dietary Supplement: Pumpkin seed extract (IRK-19)
Placebo: Dietary fiber powder, two capsules/day (600 mg/day), continued use for 3 months Treatment: Pumpkin seed extract powder, two capsules/day (600 mg/day), continued use for 3 months
|
Outcome Measures
Primary Outcome Measures
- Anthropometric measurement [Week 0]
Body weight
- Anthropometric measurement [Week 6]
Body weight
- Anthropometric measurement [Week 12]
Body weight
- Anthropometric measurement [Week 0]
Waist circumference
- Anthropometric measurement [Week 6]
Waist circumference
- Anthropometric measurement [Week 12]
Waist circumference
- Anthropometric measurement [Week 0]
Hip circumference
- Anthropometric measurement [Week 6]
Hip circumference
- Anthropometric measurement [Week 12]
Hip circumference
- Body composition analysis [Week 0]
Body fat
- Body composition analysis [Week 6]
Body fat
- Body composition analysis [Week 12]
Body fat
- Body composition analysis [Week 0]
Visceral fat
- Body composition analysis [Week 6]
Visceral fat
- Body composition analysis [Week 12]
Visceral fat
- Body composition analysis [Week 0]
Subcutaneous fat
- Body composition analysis [Week 6]
Subcutaneous fat
- Body composition analysis [Week 12]
Subcutaneous fat
- Biochemistry [Week 0]
Total cholesterol
- Biochemistry [Week 6]
Total cholesterol
- Biochemistry [Week 12]
Total cholesterol
- Biochemistry [Week 0]
Triacylglycerol
- Biochemistry [Week 6]
Triacylglycerol
- Biochemistry [Week 12]
Triacylglycerol
- Biochemistry [Week 0]
HDL
- Biochemistry [Week 6]
HDL
- Biochemistry [Week 12]
HDL
- Biochemistry [Week 0]
LDL
- Biochemistry [Week 6]
LDL
- Biochemistry [Week 12]
LDL
- Biochemistry [Week 0]
Adiponectin
- Biochemistry [Week 6]
Adiponectin
- Biochemistry [Week 12]
Adiponectin
- Biochemistry [Week 0]
Lectin
- Biochemistry [Week 6]
Lectin
- Biochemistry [Weeks 12]
Lectin
- Biochemistry [Week 0]
Fasting blood glucose
- Biochemistry [Week 6]
Fasting blood glucose
- Biochemistry [Week 12]
Fasting blood glucose
- Biochemistry [Week 0]
Insulin
- Biochemistry [Week 6]
Insulin
- Biochemistry [Week 12]
Insulin
Eligibility Criteria
Criteria
Inclusion Criteria:
-
BMI: 25-30 kg/m2
-
Waistline circumference: ˃ 80 cm
Exclusion Criteria:
-
Pregnant women or preparing for pregnancy.
-
Lactating women.
-
Women gave birth 6 months before the study.
-
Subject uses diuretic, corticosteroids, anti-depressant medications, or antipsychotic medications.
-
Subject has undertaken obesity-related surgeries within one year prior to the study or other surgeries within six months prior to the study.
-
Change of body weight of subject is over 5% within 3 months before the study.
-
Subject has serious diseases (e.g., cardiovascular diseases).
-
Cancer patient.
-
Subject has engaged in another study within 3 months before the study.
-
Subject uses another dietary supplement related to weight management during the study.
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- Greenyn Biotechnology Co., Ltd.
- Taipei Medical University WanFang Hospital
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- G-CAZ0040161110628-1