SELECT: Semaglutide Effects on Heart Disease and Stroke in Patients With Overweight or Obesity
Sponsor
Novo Nordisk A/S (Industry)
Overall Status
Active, not recruiting
CT.gov ID
NCT03574597
Collaborator
(none)
17,500
815
2
59.1
21.5
0.4
Study Details
Study Description
Brief Summary
The researchers are doing the study to see if semaglutide may reduce the risk of having cardiovascular events in patients with overweight or obesity and with prior cardiovascular disease. The participant will either get semaglutide (active medicine) or placebo ("dummy" medicine). Which treatment the participants get is decided by chance. The participant's chance of getting semaglutide or placebo is the same. The participant will get the study medicine in a pen. The participants will need to use the pen to inject the study medicine in a skinfold once a week. The study will last for about 2.5 to 5 years. Participants will have up to 25 clinic visits with the study doctor.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Phase 3 |
Study Design
Study Type:
Interventional
Anticipated Enrollment
:
17500 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Masking:
Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Masking Description:
Sponsor staff involved in the clinical trial is masked according to company standard procedures
Primary Purpose:
Treatment
Official Title:
SELECT - Semaglutide Effects on Cardiovascular Outcomes in People With Overweight or Obesity
Actual Study Start Date
:
Oct 24, 2018
Anticipated Primary Completion Date
:
Sep 28, 2023
Anticipated Study Completion Date
:
Sep 28, 2023
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Experimental: Semaglutide Participants will receive semaglutide as an adjunct to standard-of-care. Estimated trial duration for an individual subject is from 31 to 59 months. |
Drug: Semaglutide
Semaglutide will be injected into a skin fold, in the stomach, thigh or upper arm once a week at the same day of the week (to the extent possible) throughout the trial. Subjects will start semaglutide treatment at 0.24 mg; dose will gradually be increased every 4 weeks up to 2.4 mg.
|
| Placebo Comparator: Placebo (semaglutide) Participants will receive placebo (semaglutide) as an adjunct to standard-of-care. Estimated trial duration for an individual subject is from 31 to 59 months. |
Drug: Placebo (semaglutide)
Placebo will be injected into a skin fold, in the stomach, thigh or upper arm once a week at the same day of the week (to the extent possible) throughout the trial. Participants will receive placebo at an equivalent dose to semaglutide.
|
Outcome Measures
Primary Outcome Measures
- Time to first occurrence of a composite endpoint consisting of: cardiovascular (CV) death, non-fatal myocardial infarction, or non-fatal stroke [0-59 months]
Measured in months
Secondary Outcome Measures
- Time to CV death [0-59 months]
Measured in months
- Time to all-cause death [0-59 months]
Measured in months
- Time to first occurrence of an expanded composite CV endpoint consisting of: CV death, non-fatal myocardial infarction, non-fatal stroke, coronary revascularisation or unstable angina requiring hospitalisation [0-59 months]
Measured in months
- Time to first occurrence of a composite heart failure endpoint consisting of: heart failure hospitalisation, urgent heartfailure visit or CV death [0-59 months]
Measured in months
- Time to first occurrence of a composite endpoint consisting of: all-cause death, non-fatal myocardial infarction, or non-fatal stroke [0-59 months]
Measured in months
- Time to first occurrence of non-fatal myocardial infarction [0-59 months]
Measured in months
- Time to first occurrence of non-fatal stroke [0-59 months]
Measured in months
- Time to first occurrence of coronary revascularisation [0-59 months]
Measured in months
- Time to first occurrence of unstable angina requiring hospitalisation [0-59 months]
Measured in months
- Time to first occurrence of heart failure hospitalisation or urgent heart failure visit [0-59 months]
Measured in months
- Time to first occurrence of HbA1c greater than or equal to 48 mmol/mol (6.5%) [0-59 months]
Measured in months
- Time to first occurrence of a 5-component composite nephropathy endpoint [0-59 months]
Measured in months. A 5-component composite nephropathy endpoint consists of: onset of persistent macroalbuminuria (UACR above 300 mg/g), persistent 50% reduction in estimated Glomerular Filtration Rate (eGFR) compared with baseline (randomisation), onset of persistent eGFR less than 15 ml/min/1.73m^2, initiation of chronic renal replacement therapy (dialysis or transplantation) or renal death.
- Time to HbA1c greater than or equal to 39 mmol/mol (5.7%) for subjects with a screening HbA1c less than 39 mmol/mol (5.7%) [0-59 months]
Measured in months
- Subjects with HbA1c less than 39 mmol/mol (5.7%) at each visit where HbA1c is assessed for subjects with a screening HbA1c greater than or equal to 39 mmol/mol (5.7%) [0-59 months]
Proportion of subjects
- Change in systolic blood pressure [Week 0, year 2]
Measured in mm Hg
- Change in diastolic blood pressure [Week 0, year 2]
Measured in mm Hg
- Change in pulse [Week 0, year 2]
Measured in beats per minute
- Change in High sensitivity C-Reactive Protein (hsCRP) [Week 0, year 2]
Measured in mg/dL
- Change in total cholesterol [Week 0, year 2]
Measured in mg/dL
- Change in high density lipoprotein (HDL) cholesterol [Week 0, year 2]
Measured in mg/dL
- Change in low density lipoprotein (LDL) cholesterol [Week 0, year 2]
Measured in mg/dL
- Change in triglycerides [Week 0, year 2]
Measured in mg/dL
- Change in body weight [Week 0, year 2]
Measured in %
- Change in waist circumference [Week 0, year 2]
Measured in cm
- Change in EuroQol five dimensions five level (EQ-5D-5L) questionnaire [Week 0, year 2]
The EQ-5D-5L questionnaire will be used to estimate the impact on subjects' health-related quality of life and provides a description of subjects' problems by dimensions (descriptive system), a score for overall self-rated health (visual analogue scale [VAS]) as well as an index score (EQ-5D-5L index). EQ-5D index score range: 0 to 1 and EQ-5D-VAS: range 0 to 100. A higher score indicates better self reported health status.
- Change in total score weight related sign and symptom measure [Week 0, year 2]
The weight related sign and symptom measure assesses the presence and bother associated with weight-related symptoms using a self-rated VAS. It is a tool to assess the multifaceted aspects of obesity on symptom experience in subjects with overweight or obesity.
- Change in haemoglobin A1c (HbA1c) [Screening (up to 3 weeks before randomisation at week 0), week 104]
Measured in %
- Change in HbA1c [Screening (up to 3 weeks before randomisation at week 0), week 104]
Measured in mmol/mol
Eligibility Criteria
Criteria
Ages Eligible for Study:
45 Years
and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
-
Male or female, age greater than or equal to 45 years at the time of signing informed consent
-
Body mass index (BMI) greater than or equal to 27 kg/m^2
-
Have established cardiovascular (CV) disease as evidenced by at least one of the following: prior myocardial infarction; prior stroke (ischemic or haemorrhagic stroke); or symptomatic peripheral arterial disease (PAD), as evidenced by intermittent claudication with ankle-brachial index (ABI) less than 0.85 (at rest), or peripheral arterial revascularization procedure, or amputation due to atherosclerotic disease
Exclusion Criteria:
-
Any of the following: myocardial infarction, stroke, hospitalisation for unstable angina pectoris or transient ischaemic attack within the past 60 days prior to the day of screening
-
HbA1c greater than or equal to 48 mmol/mol (6.5 %) as measured by the central laboratory at screening
-
History of type 1 or type 2 diabetes (history of gestational diabetes is allowed)
Contacts and Locations
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| 243 | Novo Nordisk Investigational Site | Bruxelles | Belgium | 1070 | |
| 244 | Novo Nordisk Investigational Site | Genk | Belgium | 3600 | |
| 245 | Novo Nordisk Investigational Site | Gent | Belgium | 9000 | |
| 246 | Novo Nordisk Investigational Site | Hasselt | Belgium | 3500 | |
| 247 | Novo Nordisk Investigational Site | Salvador | Bahia | Brazil | 41950-275 |
| 248 | Novo Nordisk Investigational Site | Brasilia | Distrito Federal | Brazil | 70390-700 |
| 249 | Novo Nordisk Investigational Site | Uberlândia | Minas Gerais | Brazil | 38411-186 |
| 250 | Novo Nordisk Investigational Site | Curitiba | Parana | Brazil | 80030-480 |
| 251 | Novo Nordisk Investigational Site | Curitiba | Parana | Brazil | 80730-150 |
| 252 | Novo Nordisk Investigational Site | Passo Fundo | Rio Grande Do Sul | Brazil | 99010-080 |
| 253 | Novo Nordisk Investigational Site | Blumenau | Santa Catarina | Brazil | 89020-430 |
| 254 | Novo Nordisk Investigational Site | Campinas | Sao Paulo | Brazil | 13060-080 |
| 255 | Novo Nordisk Investigational Site | São José do Rio Preto | Sao Paulo | Brazil | 15090-000 |
| 256 | Novo Nordisk Investigational Site | São Paulo | Sao Paulo | Brazil | 01228-000 |
| 257 | Novo Nordisk Investigational Site | São Paulo | Sao Paulo | Brazil | 01228-200 |
| 258 | Novo Nordisk Investigational Site | São Paulo | Sao Paulo | Brazil | 04005-000 |
| 259 | Novo Nordisk Investigational Site | São Paulo | Sao Paulo | Brazil | 04012-909 |
| 260 | Novo Nordisk Investigational Site | São Paulo | Sao Paulo | Brazil | 05403-000 |
| 261 | Novo Nordisk Investigational Site | Rio de Janeiro | Brazil | 20241-180 | |
| 262 | Novo Nordisk Investigational Site | Dimitrovgrad | Bulgaria | 6400 | |
| 263 | Novo Nordisk Investigational Site | Lukovit | Bulgaria | 5770 | |
| 264 | Novo Nordisk Investigational Site | Pazardzhik | Bulgaria | 4400 | |
| 265 | Novo Nordisk Investigational Site | Pleven | Bulgaria | 5800 | |
| 266 | Novo Nordisk Investigational Site | Plovdiv | Bulgaria | 4002 | |
| 267 | Novo Nordisk Investigational Site | Razgrad | Bulgaria | 7200 | |
| 268 | Novo Nordisk Investigational Site | Sofia | Bulgaria | 1309 | |
| 269 | Novo Nordisk Investigational Site | Sofia | Bulgaria | 1407 | |
| 270 | Novo Nordisk Investigational Site | Sofia | Bulgaria | 1431 | |
| 271 | Novo Nordisk Investigational Site | Sofia | Bulgaria | 1527 | |
| 272 | Novo Nordisk Investigational Site | Sofia | Bulgaria | 1606 | |
| 273 | Novo Nordisk Investigational Site | Sofia | Bulgaria | 1750 | |
| 274 | Novo Nordisk Investigational Site | Varna | Bulgaria | 9002 | |
| 275 | Novo Nordisk Investigational Site | Calgary | Alberta | Canada | T2T 5C7 |
| 276 | Novo Nordisk Investigational Site | Calgary | Alberta | Canada | T2V 4J2 |
| 277 | Novo Nordisk Investigational Site | Sherwood Park | Alberta | Canada | T8H 0N2 |
| 278 | Novo Nordisk Investigational Site | Moncton | New Brunswick | Canada | E1G 1A7 |
| 279 | Novo Nordisk Investigational Site | Brampton | Ontario | Canada | L6Z 4N5 |
| 280 | Novo Nordisk Investigational Site | Burlington | Ontario | Canada | L7M 4Y1 |
| 281 | Novo Nordisk Investigational Site | Cambridge | Ontario | Canada | N1R 6V6 |
| 282 | Novo Nordisk Investigational Site | Hamilton | Ontario | Canada | L8L 2X2 |
| 283 | Novo Nordisk Investigational Site | London | Ontario | Canada | N6A 4V2 |
| 284 | Novo Nordisk Investigational Site | Nepean | Ontario | Canada | K2J 4A7 |
| 285 | Novo Nordisk Investigational Site | North York | Ontario | Canada | M6B 3H7 |
| 286 | Novo Nordisk Investigational Site | Oshawa | Ontario | Canada | L1J 2K1 |
| 287 | Novo Nordisk Investigational Site | Peterborough | Ontario | Canada | K9J 0B2 |
| 288 | Novo Nordisk Investigational Site | Port Perry | Ontario | Canada | L9L 1L9 |
| 289 | Novo Nordisk Investigational Site | Scarborough | Ontario | Canada | M1B 4Z8 |
| 290 | Novo Nordisk Investigational Site | Stoney Creek | Ontario | Canada | L8J 3W2 |
| 291 | Novo Nordisk Investigational Site | Thunder Bay | Ontario | Canada | P7A 4V7 |
| 292 | Novo Nordisk Investigational Site | Toronto | Ontario | Canada | M9W 4L6 |
| 293 | Novo Nordisk Investigational Site | Brossard | Quebec | Canada | J4Z 2K9 |
| 294 | Novo Nordisk Investigational Site | Levis | Quebec | Canada | G6W 0M5 |
| 295 | Novo Nordisk Investigational Site | Mirabel | Quebec | Canada | J7J 2K8 |
| 296 | Novo Nordisk Investigational Site | Montreal | Quebec | Canada | H1T 3Y7 |
| 297 | Novo Nordisk Investigational Site | Montreal | Quebec | Canada | H2W 1R7 |
| 298 | Novo Nordisk Investigational Site | Montreal | Quebec | Canada | H4A 3T2 |
| 299 | Novo Nordisk Investigational Site | Pointe-Claire | Quebec | Canada | H9R 4S3 |
| 300 | Novo Nordisk Investigational Site | Québec | Quebec | Canada | G1V 4W2 |
| 301 | Novo Nordisk Investigational Site | Sherbrooke | Quebec | Canada | J1H 5N4 |
| 302 | Novo Nordisk Investigational Site | St-Marc-des-Carrières | Quebec | Canada | G0A 4B0 |
| 303 | Novo Nordisk Investigational Site | Terrebonne | Quebec | Canada | J6V 2H2 |
| 304 | Novo Nordisk Investigational Site | Quebec | Canada | G1V 4G5 | |
| 305 | Novo Nordisk Investigational Site | Barranquilla | Colombia | 080001 | |
| 306 | Novo Nordisk Investigational Site | Barranquilla | Colombia | 080020 | |
| 307 | Novo Nordisk Investigational Site | Barranquilla | Colombia | 80020 | |
| 308 | Novo Nordisk Investigational Site | Floridablanca | Colombia | 681004 | |
| 309 | Novo Nordisk Investigational Site | Medellin | Colombia | 050021 | |
| 310 | Novo Nordisk Investigational Site | Medellin | Colombia | 050030 | |
| 311 | Novo Nordisk Investigational Site | Medellin | Colombia | 050034 | |
| 312 | Novo Nordisk Investigational Site | Krapinske Toplice | Croatia | 49217 | |
| 313 | Novo Nordisk Investigational Site | Osijek | Croatia | 31 000 | |
| 314 | Novo Nordisk Investigational Site | Rijeka | Croatia | 51000 | |
| 315 | Novo Nordisk Investigational Site | Zagreb | Croatia | 10000 | |
| 316 | Novo Nordisk Investigational Site | Broumov | Czechia | 550 01 | |
| 317 | Novo Nordisk Investigational Site | Chomutov | Czechia | 430 02 | |
| 318 | Novo Nordisk Investigational Site | Hradec Kralove | Czechia | 500 05 | |
| 319 | Novo Nordisk Investigational Site | Jihlava | Czechia | 586 33 | |
| 320 | Novo Nordisk Investigational Site | Liberec | Czechia | 460 63 | |
| 321 | Novo Nordisk Investigational Site | Olomouc | Czechia | 77520 | |
| 322 | Novo Nordisk Investigational Site | Policka | Czechia | 572 01 | |
| 323 | Novo Nordisk Investigational Site | Praha 2 | Czechia | 128 08 | |
| 324 | Novo Nordisk Investigational Site | Praha 4 | Czechia | 140 00 | |
| 325 | Novo Nordisk Investigational Site | Praha 8 | Czechia | 181 00 | |
| 326 | Novo Nordisk Investigational Site | Slany | Czechia | 274 01 | |
| 327 | Novo Nordisk Investigational Site | Svitavy | Czechia | 568 25 | |
| 328 | Novo Nordisk Investigational Site | Tabor | Czechia | 39003 | |
| 329 | Novo Nordisk Investigational Site | Aalborg | Denmark | 9000 | |
| 330 | Novo Nordisk Investigational Site | Aarhus N | Denmark | 8200 | |
| 331 | Novo Nordisk Investigational Site | Hellerup | Denmark | 2900 | |
| 332 | Novo Nordisk Investigational Site | Herning | Denmark | 7400 | |
| 333 | Novo Nordisk Investigational Site | Hvidovre | Denmark | 2650 | |
| 334 | Novo Nordisk Investigational Site | Svendborg | Denmark | 5700 | |
| 335 | Novo Nordisk Investigational Site | Jyväskylä | Finland | 40620 | |
| 336 | Novo Nordisk Investigational Site | Kuopio | Finland | 70100 | |
| 337 | Novo Nordisk Investigational Site | Lahti | Finland | 15850 | |
| 338 | Novo Nordisk Investigational Site | Oulu | Finland | 90220 | |
| 339 | Novo Nordisk Investigational Site | Seinäjoki | Finland | 60220 | |
| 340 | Novo Nordisk Investigational Site | Tampere | Finland | 33520 | |
| 341 | Novo Nordisk Investigational Site | Turku | Finland | 20520 | |
| 342 | Novo Nordisk Investigational Site | Besançon | France | 25030 | |
| 343 | Novo Nordisk Investigational Site | Bondy | France | 93143 | |
| 344 | Novo Nordisk Investigational Site | Corbeil Essonnes | France | 91106 | |
| 345 | Novo Nordisk Investigational Site | DIJON cedex | France | 21079 | |
| 346 | Novo Nordisk Investigational Site | La Tronche | France | 38700 | |
| 347 | Novo Nordisk Investigational Site | Le Coudray | France | 28630 | |
| 348 | Novo Nordisk Investigational Site | Narbonne | France | 11100 | |
| 349 | Novo Nordisk Investigational Site | Nice | France | 06000 | |
| 350 | Novo Nordisk Investigational Site | Paris Cedex 18 | France | 75877 | |
| 351 | Novo Nordisk Investigational Site | Paris | France | 75013 | |
| 352 | Novo Nordisk Investigational Site | Paris | France | 75015 | |
| 353 | Novo Nordisk Investigational Site | Paris | France | 75475 | |
| 354 | Novo Nordisk Investigational Site | Pessac | France | 33600 | |
| 355 | Novo Nordisk Investigational Site | Reims | France | 51000 | |
| 356 | Novo Nordisk Investigational Site | Saint Herblain | France | 44800 | |
| 357 | Novo Nordisk Investigational Site | Strasbourg | France | 67091 | |
| 358 | Novo Nordisk Investigational Site | Venissieux | France | 69200 | |
| 359 | Novo Nordisk Investigational Site | Aachen | Germany | 52074 | |
| 360 | Novo Nordisk Investigational Site | Bad Homburg | Germany | 61348 | |
| 361 | Novo Nordisk Investigational Site | Berlin | Germany | 10117 | |
| 362 | Novo Nordisk Investigational Site | Berlin | Germany | 10629 | |
| 363 | Novo Nordisk Investigational Site | Berlin | Germany | 12627 | |
| 364 | Novo Nordisk Investigational Site | Bochum | Germany | 44787 | |
| 365 | Novo Nordisk Investigational Site | Dresden | Germany | 01069 | |
| 366 | Novo Nordisk Investigational Site | Dresden | Germany | 01277 | |
| 367 | Novo Nordisk Investigational Site | Elsterwerda | Germany | 04910 | |
| 368 | Novo Nordisk Investigational Site | Essen | Germany | 45136 | |
| 369 | Novo Nordisk Investigational Site | Frankfurt | Germany | 60313 | |
| 370 | Novo Nordisk Investigational Site | Frankfurt | Germany | 60389 | |
| 371 | Novo Nordisk Investigational Site | Friedrichsthal | Germany | 66299 | |
| 372 | Novo Nordisk Investigational Site | Hamburg | Germany | 20253 | |
| 373 | Novo Nordisk Investigational Site | Hamburg | Germany | 22607 | |
| 374 | Novo Nordisk Investigational Site | Hannover | Germany | 30159 | |
| 375 | Novo Nordisk Investigational Site | Karlsruhe | Germany | 76137 | |
| 376 | Novo Nordisk Investigational Site | Kassel | Germany | 34121 | |
| 377 | Novo Nordisk Investigational Site | Leipzig | Germany | 04103 | |
| 378 | Novo Nordisk Investigational Site | Leipzig | Germany | 04107 | |
| 379 | Novo Nordisk Investigational Site | Ludwigshafen | Germany | 67059 | |
| 380 | Novo Nordisk Investigational Site | Lübeck | Germany | 23562 | |
| 381 | Novo Nordisk Investigational Site | Oldenburg I. Holst | Germany | 23758 | |
| 382 | Novo Nordisk Investigational Site | Pirna | Germany | 01796 | |
| 383 | Novo Nordisk Investigational Site | Saint Ingbert-Oberwürzbach | Germany | 66386 | |
| 384 | Novo Nordisk Investigational Site | Schkeuditz | Germany | 04435 | |
| 385 | Novo Nordisk Investigational Site | Schwerin | Germany | 19055 | |
| 386 | Novo Nordisk Investigational Site | Villingen-Schwenningen | Germany | 78048 | |
| 387 | Novo Nordisk Investigational Site | Wangen | Germany | 88239 | |
| 388 | Novo Nordisk Investigational Site | Wermsdorf | Germany | 04779 | |
| 389 | Novo Nordisk Investigational Site | Witten | Germany | 58455 | |
| 390 | Novo Nordisk Investigational Site | Athens | Greece | 17674 | |
| 391 | Novo Nordisk Investigational Site | Athens | Greece | GR-11527 | |
| 392 | Novo Nordisk Investigational Site | Athens | Greece | GR-11528 | |
| 393 | Novo Nordisk Investigational Site | Athens | Greece | GR-14233 | |
| 394 | Novo Nordisk Investigational Site | Athens | Greece | GR-15123 | |
| 395 | Novo Nordisk Investigational Site | Athens | Greece | GR-15125 | |
| 396 | Novo Nordisk Investigational Site | Chios | Greece | GR82100 | |
| 397 | Novo Nordisk Investigational Site | Haidari-Athens | Greece | GR-12462 | |
| 398 | Novo Nordisk Investigational Site | Ioannina | Greece | 45500 | |
| 399 | Novo Nordisk Investigational Site | Lamia | Greece | GR35100 | |
| 400 | Novo Nordisk Investigational Site | Larissa | Greece | GR-41110 | |
| 401 | Novo Nordisk Investigational Site | Thessaloniki | Greece | GR-54636 | |
| 402 | Novo Nordisk Investigational Site | Thessaloniki | Greece | GR-57001 | |
| 403 | Novo Nordisk Investigational Site | Baja | Hungary | 6500 | |
| 404 | Novo Nordisk Investigational Site | Budapest | Hungary | 1152 | |
| 405 | Novo Nordisk Investigational Site | Gyöngyös | Hungary | 3200 | |
| 406 | Novo Nordisk Investigational Site | Szeged | Hungary | H-6725 | |
| 407 | Novo Nordisk Investigational Site | Szombathely | Hungary | H-9700 | |
| 408 | Novo Nordisk Investigational Site | Zalaegerszeg | Hungary | 8900 | |
| 409 | Novo Nordisk Investigational Site | Hyderabad | Andhra Pradesh | India | 500020 |
| 410 | Novo Nordisk Investigational Site | Vijayawada | Andhra Pradesh | India | 520008 |
| 411 | Novo Nordisk Investigational Site | Ahmedabad | Gujarat | India | 380054 |
| 412 | Novo Nordisk Investigational Site | Ahmedabad | Gujarat | India | 380060 |
| 413 | Novo Nordisk Investigational Site | Surat | Gujarat | India | 395001 |
| 414 | Novo Nordisk Investigational Site | Surat | Gujarat | India | 395002 |
| 415 | Novo Nordisk Investigational Site | Gurgaon | Haryana | India | 122001 |
| 416 | Novo Nordisk Investigational Site | Bangalore | Karnataka | India | 560069 |
| 417 | Novo Nordisk Investigational Site | Manipal | Karnataka | India | 576104 |
| 418 | Novo Nordisk Investigational Site | Aurangabad | Maharashtra | India | 431005 |
| 419 | Novo Nordisk Investigational Site | Mumbai | Maharashtra | India | 400012 |
| 420 | Novo Nordisk Investigational Site | Mumbai | Maharashtra | India | 400022 |
| 421 | Novo Nordisk Investigational Site | Mumbai | Maharashtra | India | 400050 |
| 422 | Novo Nordisk Investigational Site | Nagpur | Maharashtra | India | 440010 |
| 423 | Novo Nordisk Investigational Site | Nagpur | Maharashtra | India | 440012 |
| 424 | Novo Nordisk Investigational Site | Nashik | Maharashtra | India | 422005 |
| 425 | Novo Nordisk Investigational Site | Pune | Maharashtra | India | 411001 |
| 426 | Novo Nordisk Investigational Site | Pune | Maharashtra | India | 411004 |
| 427 | Novo Nordisk Investigational Site | Delhi | New Delhi | India | 110002 |
| 428 | Novo Nordisk Investigational Site | New Dehli | New Delhi | India | 110029 |
| 429 | Novo Nordisk Investigational Site | Amritsar | Punjab | India | 143004 |
| 430 | Novo Nordisk Investigational Site | Bikaner | Rajasthan | India | 334003 |
| 431 | Novo Nordisk Investigational Site | Chennai | Tamil Nadu | India | 600037 |
| 432 | Novo Nordisk Investigational Site | Coimbatore | Tamil Nadu | India | 641037 |
| 433 | Novo Nordisk Investigational Site | Vellore | Tamil Nadu | India | 632004 |
| 434 | Novo Nordisk Investigational Site | Hyderbad | Telengana | India | 500 012 |
| 435 | Novo Nordisk Investigational Site | Lucknow | Uttar Pradesh | India | 226003 |
| 436 | Novo Nordisk Investigational Site | Kolkata | West Bengal | India | 700027 |
| 437 | Novo Nordisk Investigational Site | Bangalore | India | 560 099 | |
| 438 | Novo Nordisk Investigational Site | Bangalore | India | 560034 | |
| 439 | Novo Nordisk Investigational Site | Ludhiana | India | 141001 | |
| 440 | Novo Nordisk Investigational Site | New Delhi | India | 110005 | |
| 441 | Novo Nordisk Investigational Site | New Delhi | India | 110060 | |
| 442 | Novo Nordisk Investigational Site | New Delhi | India | 110062 | |
| 443 | Novo Nordisk Investigational Site | Dublin | Ireland | A96 D628 | |
| 444 | Novo Nordisk Investigational Site | Dublin | Ireland | D04 T6F4 | |
| 445 | Novo Nordisk Investigational Site | Dublin | Ireland | D09 V2N0 | |
| 446 | Novo Nordisk Investigational Site | Dublin | Ireland | D24NR0A | |
| 447 | Novo Nordisk Investigational Site | Dublin | Ireland | DUBLIN 15 | |
| 448 | Novo Nordisk Investigational Site | Dublin | Ireland | DUBLIN 4 | |
| 449 | Novo Nordisk Investigational Site | Dublin | Ireland | DUBLIN 7 | |
| 450 | Novo Nordisk Investigational Site | Galway | Ireland | H91 YR71 | |
| 451 | Novo Nordisk Investigational Site | Mallow | Ireland | P51Y8EC | |
| 452 | Novo Nordisk Investigational Site | Beer Sheva | Israel | 84101 | |
| 453 | Novo Nordisk Investigational Site | Haifa | Israel | 31096 | |
| 454 | Novo Nordisk Investigational Site | Jerusalem | Israel | 91120 | |
| 455 | Novo Nordisk Investigational Site | Kfar Saba | Israel | 44281 | |
| 456 | Novo Nordisk Investigational Site | Nahariya | Israel | 22100 | |
| 457 | Novo Nordisk Investigational Site | Petah-Tikva | Israel | 49372 | |
| 458 | Novo Nordisk Investigational Site | Rehovot | Israel | 76100 | |
| 459 | Novo Nordisk Investigational Site | Tel Aviv | Israel | 6423906 | |
| 460 | Novo Nordisk Investigational Site | Tel Hashomer | Israel | 52621 | |
| 461 | Novo Nordisk Investigational Site | Tel Hashomer | Israel | 5265601 | |
| 462 | Novo Nordisk Investigational Site | Tel-Aviv | Israel | 64239 | |
| 463 | Novo Nordisk Investigational Site | Bergamo | Italy | 24127 | |
| 464 | Novo Nordisk Investigational Site | Bologna | Italy | 40138 | |
| 465 | Novo Nordisk Investigational Site | Catania | Italy | 95122 | |
| 466 | Novo Nordisk Investigational Site | Chieti Scalo | Italy | 66100 | |
| 467 | Novo Nordisk Investigational Site | Como | Italy | 22042 | |
| 468 | Novo Nordisk Investigational Site | Cona - Ferrara | Italy | 44124 | |
| 469 | Novo Nordisk Investigational Site | Firenze | Italy | 50134 | |
| 470 | Novo Nordisk Investigational Site | Genova | Italy | 16132 | |
| 471 | Novo Nordisk Investigational Site | Latina | Italy | 04100 | |
| 472 | Novo Nordisk Investigational Site | Napoli | Italy | 80131 | |
| 473 | Novo Nordisk Investigational Site | Padova | Italy | 35128 | |
| 474 | Novo Nordisk Investigational Site | Palermo | Italy | 90127 | |
| 475 | Novo Nordisk Investigational Site | Pavia | Italy | 27100 | |
| 476 | Novo Nordisk Investigational Site | Pisa | Italy | 56124 | |
| 477 | Novo Nordisk Investigational Site | Roma | Italy | 00128 | |
| 478 | Novo Nordisk Investigational Site | Roma | Italy | 00133 | |
| 479 | Novo Nordisk Investigational Site | Rome | Italy | 00168 | |
| 480 | Novo Nordisk Investigational Site | Rozzano (MI) | Italy | 20089 | |
| 481 | Novo Nordisk Investigational Site | San Donato Milanese (MI) | Italy | 20097 | |
| 482 | Novo Nordisk Investigational Site | Savigliano (CN) | Italy | 12038 | |
| 483 | Novo Nordisk Investigational Site | Sesto San Giovanni (MI) | Italy | 20099 | |
| 484 | Novo Nordisk Investigational Site | Siena | Italy | 53100 | |
| 485 | Novo Nordisk Investigational Site | Torino | Italy | 10126 | |
| 486 | Novo Nordisk Investigational Site | Adachi-ku, Tokyo | Japan | 123-0845 | |
| 487 | Novo Nordisk Investigational Site | Asahikawa, Hokkaido | Japan | 078-8237 | |
| 488 | Novo Nordisk Investigational Site | Bunkyo-ku, Tokyo | Japan | 113-8655 | |
| 489 | Novo Nordisk Investigational Site | Chiba | Japan | 271-0077 | |
| 490 | Novo Nordisk Investigational Site | Chikushino-shi, Fukuoka | Japan | 818-8516 | |
| 491 | Novo Nordisk Investigational Site | Ehime | Japan | 790-0024 | |
| 492 | Novo Nordisk Investigational Site | Funabashi-shi, Chiba | Japan | 274-8503 | |
| 493 | Novo Nordisk Investigational Site | Gifu-city, Gifu | Japan | 500-8384 | |
| 494 | Novo Nordisk Investigational Site | Hirakata-shi, Osaka | Japan | 573-0153 | |
| 495 | Novo Nordisk Investigational Site | Hiroshima-shi, Hiroshima | Japan | 732-0057 | |
| 496 | Novo Nordisk Investigational Site | Kagoshima-shi, Kagoshima | Japan | 892-0828 | |
| 497 | Novo Nordisk Investigational Site | Kanagawa | Japan | 235-0045 | |
| 498 | Novo Nordisk Investigational Site | Kasugai-shi, Aichi | Japan | 486-8510 | |
| 499 | Novo Nordisk Investigational Site | Kawaguchi-shi, Saitama | Japan | 332-0012 | |
| 500 | Novo Nordisk Investigational Site | Kitakyushu-shi, Fukuoka | Japan | 805-8508 | |
| 501 | Novo Nordisk Investigational Site | Kochi-shi, Kochi | Japan | 780-8522 | |
| 502 | Novo Nordisk Investigational Site | Kumamoto-shi, Kumamoto | Japan | 861-4193 | |
| 503 | Novo Nordisk Investigational Site | Kyoto-shi, Kyoto | Japan | 600-8558 | |
| 504 | Novo Nordisk Investigational Site | Kyoto-shi,Kyoto | Japan | 601-1495 | |
| 505 | Novo Nordisk Investigational Site | Kyoto | Japan | 611-0041 | |
| 506 | Novo Nordisk Investigational Site | Matsuyama-shi, Ehime | Japan | 790-0062 | |
| 507 | Novo Nordisk Investigational Site | Miyagi | Japan | 983-0039 | |
| 508 | Novo Nordisk Investigational Site | Moriyama-shi, Shiga | Japan | 524-8524 | |
| 509 | Novo Nordisk Investigational Site | Nagoya-shi, Aichi | Japan | 454-8502 | |
| 510 | Novo Nordisk Investigational Site | Naha-shi, Okinawa | Japan | 902-8511 | |
| 511 | Novo Nordisk Investigational Site | Okawa-shi, Fukuoka | Japan | 831-0016 | |
| 512 | Novo Nordisk Investigational Site | Okayama-shi, Okayama | Japan | 701-1192 | |
| 513 | Novo Nordisk Investigational Site | Osaka-city, Osaka | Japan | 530-0001 | |
| 514 | Novo Nordisk Investigational Site | Osaka | Japan | 569-1045 | |
| 515 | Novo Nordisk Investigational Site | Saga-shi, Saga | Japan | 849-8501 | |
| 516 | Novo Nordisk Investigational Site | Sapporo-shi, Hokkaido | Japan | 004-0004 | |
| 517 | Novo Nordisk Investigational Site | Sapporo-shi, Hokkaido | Japan | 062-0003 | |
| 518 | Novo Nordisk Investigational Site | Sapporo-shi, Hokkaido | Japan | 064-8570 | |
| 519 | Novo Nordisk Investigational Site | Sendai-shi, Miyagi | Japan | 980-0873 | |
| 520 | Novo Nordisk Investigational Site | Shinjuku-ku, Tokyo | Japan | 162-8655 | |
| 521 | Novo Nordisk Investigational Site | Takamatsu-shi, Kagawa | Japan | 760-0073 | |
| 522 | Novo Nordisk Investigational Site | Takamatsu-shi, Kagawa | Japan | 760-8557 | |
| 523 | Novo Nordisk Investigational Site | Takasaki-shi, Gunma | Japan | 370-3513 | |
| 524 | Novo Nordisk Investigational Site | Tokorozawa-shi, Saitama | Japan | 356-1142 | |
| 525 | Novo Nordisk Investigational Site | Tokorozawa-shi,Saitama | Japan | 359-1141 | |
| 526 | Novo Nordisk Investigational Site | Tokyo | Japan | 103-0027 | |
| 527 | Novo Nordisk Investigational Site | Tokyo | Japan | 104-0031 | |
| 528 | Novo Nordisk Investigational Site | Tokyo | Japan | 140-8522 | |
| 529 | Novo Nordisk Investigational Site | Tokyo | Japan | 192-0918 | |
| 530 | Novo Nordisk Investigational Site | Wako-city, Saitama | Japan | 351-0102 | |
| 531 | Novo Nordisk Investigational Site | Yanagawa-shi, Fukuoka | Japan | 832-0059 | |
| 532 | Novo Nordisk Investigational Site | Yokosuka-shi, Kanagawa | Japan | 238-856 | |
| 533 | Novo Nordisk Investigational Site | Daugavpils | Latvia | LV5401 | |
| 534 | Novo Nordisk Investigational Site | Liepaja | Latvia | LV-3414 | |
| 535 | Novo Nordisk Investigational Site | Ogre | Latvia | LV-5001 | |
| 536 | Novo Nordisk Investigational Site | Riga | Latvia | LV-1002 | |
| 537 | Novo Nordisk Investigational Site | Riga | Latvia | LV-1011 | |
| 538 | Novo Nordisk Investigational Site | Riga | Latvia | LV1011 | |
| 539 | Novo Nordisk Investigational Site | Riga | Latvia | LV1012 | |
| 540 | Novo Nordisk Investigational Site | Ventspils | Latvia | LV3601 | |
| 541 | Novo Nordisk Investigational Site | Alor Gajah | Malaysia | 78300 | |
| 542 | Novo Nordisk Investigational Site | Alor Setar | Malaysia | 05460 | |
| 543 | Novo Nordisk Investigational Site | Kota Bharu, Kelantan | Malaysia | 16150 | |
| 544 | Novo Nordisk Investigational Site | Kota Bharu | Malaysia | 15586 | |
| 545 | Novo Nordisk Investigational Site | Kota Samarahan | Malaysia | 94300 | |
| 546 | Novo Nordisk Investigational Site | Kuala Lumpur | Malaysia | 50400 | |
| 547 | Novo Nordisk Investigational Site | Kuala Lumpur | Malaysia | 59100 | |
| 548 | Novo Nordisk Investigational Site | Kuantan | Malaysia | 25100 | |
| 549 | Novo Nordisk Investigational Site | Putrajaya | Malaysia | 62250 | |
| 550 | Novo Nordisk Investigational Site | Sabah | Malaysia | 88300 | |
| 551 | Novo Nordisk Investigational Site | Seri Manjung | Malaysia | 32040 | |
| 552 | Novo Nordisk Investigational Site | Sungai Buloh | Malaysia | 47000 | |
| 553 | Novo Nordisk Investigational Site | Torreon | Coahuila | Mexico | 27000 |
| 554 | Novo Nordisk Investigational Site | Guadalajara | Jalisco | Mexico | 44670 |
| 555 | Novo Nordisk Investigational Site | Ciudad de Mexico | México, D.F. | Mexico | 03100 |
| 556 | Novo Nordisk Investigational Site | Ciudad de Mexico | México, D.F. | Mexico | 14080 |
| 557 | Novo Nordisk Investigational Site | Monterrey | Nuevo León | Mexico | 64460 |
| 558 | Novo Nordisk Investigational Site | San Luis Potosí | San Luis Potosi | Mexico | 78200 |
| 559 | Novo Nordisk Investigational Site | Culiacán | Sinaloa | Mexico | 80230 |
| 560 | Novo Nordisk Investigational Site | Aguascalientes | Mexico | 20230 | |
| 561 | Novo Nordisk Investigational Site | Durango | Mexico | 34000 | |
| 562 | Novo Nordisk Investigational Site | Apeldoorn | Netherlands | 7334 DZ | |
| 563 | Novo Nordisk Investigational Site | Breda | Netherlands | 4818 CK | |
| 564 | Novo Nordisk Investigational Site | Deventer | Netherlands | 7416 SE | |
| 565 | Novo Nordisk Investigational Site | Groningen | Netherlands | 9713 GZ | |
| 566 | Novo Nordisk Investigational Site | Leeuwarden | Netherlands | 8934 AD | |
| 567 | Novo Nordisk Investigational Site | Leiderdorp | Netherlands | 2353 GA | |
| 568 | Novo Nordisk Investigational Site | Roosendaal | Netherlands | 4708 AE | |
| 569 | Novo Nordisk Investigational Site | Rotterdam | Netherlands | 3045 PM | |
| 570 | Novo Nordisk Investigational Site | Sneek | Netherlands | 8601 ZR | |
| 571 | Novo Nordisk Investigational Site | Tiel | Netherlands | 4002 WP | |
| 572 | Novo Nordisk Investigational Site | Bergen | Norway | 5021 | |
| 573 | Novo Nordisk Investigational Site | Hamar | Norway | 2317 | |
| 574 | Novo Nordisk Investigational Site | Lillehammer | Norway | 2609 | |
| 575 | Novo Nordisk Investigational Site | Nordbyhagen | Norway | 1474 | |
| 576 | Novo Nordisk Investigational Site | Oslo | Norway | 0372 | |
| 577 | Novo Nordisk Investigational Site | Oslo | Norway | 0450 | |
| 578 | Novo Nordisk Investigational Site | Oslo | Norway | 0586 | |
| 579 | Novo Nordisk Investigational Site | Tønsberg | Norway | 3117 | |
| 580 | Novo Nordisk Investigational Site | Ålesund | Norway | 6017 | |
| 581 | Novo Nordisk Investigational Site | Bialystok | Poland | 15-281 | |
| 582 | Novo Nordisk Investigational Site | Bialystok | Poland | 15-481 | |
| 583 | Novo Nordisk Investigational Site | Gdansk | Poland | 80-286 | |
| 584 | Novo Nordisk Investigational Site | Gdansk | Poland | 80-546 | |
| 585 | Novo Nordisk Investigational Site | Gdynia | Poland | 81-338 | |
| 586 | Novo Nordisk Investigational Site | Krakow | Poland | 30-033 | |
| 587 | Novo Nordisk Investigational Site | Krakow | Poland | 31-271 | |
| 588 | Novo Nordisk Investigational Site | Lodz | Poland | 90-242 | |
| 589 | Novo Nordisk Investigational Site | Lomza | Poland | 18-404 | |
| 590 | Novo Nordisk Investigational Site | Lowicz | Poland | 99-400 | |
| 591 | Novo Nordisk Investigational Site | Lublin | Poland | 20-044 | |
| 592 | Novo Nordisk Investigational Site | Poznan | Poland | 60-589 | |
| 593 | Novo Nordisk Investigational Site | Poznan | Poland | 61-485 | |
| 594 | Novo Nordisk Investigational Site | Pulawy | Poland | 24-100 | |
| 595 | Novo Nordisk Investigational Site | Siedlce | Poland | 08-110 | |
| 596 | Novo Nordisk Investigational Site | Skierniewice | Poland | 96-100 | |
| 597 | Novo Nordisk Investigational Site | Szczecin | Poland | 71-531 | |
| 598 | Novo Nordisk Investigational Site | Warsaw | Poland | 02-793 | |
| 599 | Novo Nordisk Investigational Site | Warszawa | Poland | 00-001 | |
| 600 | Novo Nordisk Investigational Site | Warszawa | Poland | 02-507 | |
| 601 | Novo Nordisk Investigational Site | Zamosc | Poland | 22-400 | |
| 602 | Novo Nordisk Investigational Site | Almada | Portugal | 2805-267 | |
| 603 | Novo Nordisk Investigational Site | Coimbra | Portugal | 3000-561 | |
| 604 | Novo Nordisk Investigational Site | Lisboa | Portugal | 1500-650 | |
| 605 | Novo Nordisk Investigational Site | Lisboa | Portugal | 1649-035 | |
| 606 | Novo Nordisk Investigational Site | Matosinhos | Portugal | 4464-513 | |
| 607 | Novo Nordisk Investigational Site | Porto | Portugal | 4200-319 | |
| 608 | Novo Nordisk Investigational Site | Trujillo Alto | Puerto Rico | 00976 | |
| 609 | Novo Nordisk Investigational Site | Oradea | Bihor | Romania | 410025 |
| 610 | Novo Nordisk Investigational Site | Oradea | Bihor | Romania | 410151 |
| 611 | Novo Nordisk Investigational Site | Clarasi | Calaras | Romania | 910103 |
| 612 | Novo Nordisk Investigational Site | Cluj Napoca | Cluj | Romania | 400349 |
| 613 | Novo Nordisk Investigational Site | Craiova | Dolj | Romania | 200515 |
| 614 | Novo Nordisk Investigational Site | Baia Mare | Maramures | Romania | 430222 |
| 615 | Novo Nordisk Investigational Site | Targu Mures | Mures | Romania | 540142 |
| 616 | Novo Nordisk Investigational Site | Timisoara | Timis | Romania | 300736 |
| 617 | Novo Nordisk Investigational Site | Bacau | Romania | 600281 | |
| 618 | Novo Nordisk Investigational Site | Brasov | Romania | 500283 | |
| 619 | Novo Nordisk Investigational Site | Bucharest | Romania | 010507 | |
| 620 | Novo Nordisk Investigational Site | Bucharest | Romania | 010825 | |
| 621 | Novo Nordisk Investigational Site | Bucharest | Romania | 011025 | |
| 622 | Novo Nordisk Investigational Site | Bucharest | Romania | 031818 | |
| 623 | Novo Nordisk Investigational Site | Bucharest | Romania | 13682 | |
| 624 | Novo Nordisk Investigational Site | Bucuresti | Romania | 011863 | |
| 625 | Novo Nordisk Investigational Site | Buzau | Romania | 120203 | |
| 626 | Novo Nordisk Investigational Site | Deva | Romania | 330084 | |
| 627 | Novo Nordisk Investigational Site | Galati | Romania | 800098 | |
| 628 | Novo Nordisk Investigational Site | Galati | Romania | 800291 | |
| 629 | Novo Nordisk Investigational Site | Iasi | Romania | 700469 | |
| 630 | Novo Nordisk Investigational Site | Iasi | Romania | 700547 | |
| 631 | Novo Nordisk Investigational Site | Iasi | Romania | 700687 | |
| 632 | Novo Nordisk Investigational Site | Pascani | Romania | 700502 | |
| 633 | Novo Nordisk Investigational Site | Ploiesti | Romania | 100561 | |
| 634 | Novo Nordisk Investigational Site | Satu Mare | Romania | 440055 | |
| 635 | Novo Nordisk Investigational Site | Sibiu | Romania | 550371 | |
| 636 | Novo Nordisk Investigational Site | Suceava | Romania | 720059 | |
| 637 | Novo Nordisk Investigational Site | Arkhangelsk | Russian Federation | 163001 | |
| 638 | Novo Nordisk Investigational Site | Barnaul | Russian Federation | 656024 | |
| 639 | Novo Nordisk Investigational Site | Barnaul | Russian Federation | 656045 | |
| 640 | Novo Nordisk Investigational Site | Barnaul | Russian Federation | 656055 | |
| 641 | Novo Nordisk Investigational Site | Belgorod | Russian Federation | 308007 | |
| 642 | Novo Nordisk Investigational Site | Ekaterinburg | Russian Federation | 620026 | |
| 643 | Novo Nordisk Investigational Site | Ivanovo | Russian Federation | 153012 | |
| 644 | Novo Nordisk Investigational Site | Kazan | Russian Federation | 420010 | |
| 645 | Novo Nordisk Investigational Site | Kemerovo | Russian Federation | 650002 | |
| 646 | Novo Nordisk Investigational Site | Moscow | Russian Federation | 109369 | |
| 647 | Novo Nordisk Investigational Site | Moscow | Russian Federation | 111539 | |
| 648 | Novo Nordisk Investigational Site | Moscow | Russian Federation | 117292 | |
| 649 | Novo Nordisk Investigational Site | Moscow | Russian Federation | 119991 | |
| 650 | Novo Nordisk Investigational Site | Moscow | Russian Federation | 121552 | |
| 651 | Novo Nordisk Investigational Site | Moscow | Russian Federation | 123182 | |
| 652 | Novo Nordisk Investigational Site | Moscow | Russian Federation | 127486 | |
| 653 | Novo Nordisk Investigational Site | Moscow | Russian Federation | 129128 | |
| 654 | Novo Nordisk Investigational Site | Moscow | Russian Federation | 129327 | |
| 655 | Novo Nordisk Investigational Site | Novosibirsk | Russian Federation | 630005 | |
| 656 | Novo Nordisk Investigational Site | Novosibirsk | Russian Federation | 630099 | |
| 657 | Novo Nordisk Investigational Site | Novosibirsk | Russian Federation | 630117 | |
| 658 | Novo Nordisk Investigational Site | Orenburg | Russian Federation | 460018 | |
| 659 | Novo Nordisk Investigational Site | Penza | Russian Federation | 440026 | |
| 660 | Novo Nordisk Investigational Site | Rostov-on-Don | Russian Federation | 344068 | |
| 661 | Novo Nordisk Investigational Site | Saint Petersburg | Russian Federation | 192283 | |
| 662 | Novo Nordisk Investigational Site | Saint-Petersburg, Pushkin | Russian Federation | 196601 | |
| 663 | Novo Nordisk Investigational Site | Saint-Petersburg | Russian Federation | 190013 | |
| 664 | Novo Nordisk Investigational Site | Saint-Petersburg | Russian Federation | 190121 | |
| 665 | Novo Nordisk Investigational Site | Saint-Petersburg | Russian Federation | 191119 | |
| 666 | Novo Nordisk Investigational Site | Saint-Petersburg | Russian Federation | 191186 | |
| 667 | Novo Nordisk Investigational Site | Saint-Petersburg | Russian Federation | 194156 | |
| 668 | Novo Nordisk Investigational Site | Saint-Petersburg | Russian Federation | 194358 | |
| 669 | Novo Nordisk Investigational Site | Saint-Petersburg | Russian Federation | 197022 | |
| 670 | Novo Nordisk Investigational Site | Saint-Petersburg | Russian Federation | 197762 | |
| 671 | Novo Nordisk Investigational Site | Saint-Petersburg | Russian Federation | 199226 | |
| 672 | Novo Nordisk Investigational Site | Samara | Russian Federation | 443070 | |
| 673 | Novo Nordisk Investigational Site | Sochi | Russian Federation | 354057 | |
| 674 | Novo Nordisk Investigational Site | St. Petersburg | Russian Federation | 194354 | |
| 675 | Novo Nordisk Investigational Site | Syktyvkar | Russian Federation | 167981 | |
| 676 | Novo Nordisk Investigational Site | Tomsk | Russian Federation | 634012 | |
| 677 | Novo Nordisk Investigational Site | Tomsk | Russian Federation | 634041 | |
| 678 | Novo Nordisk Investigational Site | Tomsk | Russian Federation | 634050 | |
| 679 | Novo Nordisk Investigational Site | Tumen | Russian Federation | 625023 | |
| 680 | Novo Nordisk Investigational Site | Tver | Russian Federation | 170036 | |
| 681 | Novo Nordisk Investigational Site | Ulianovsk | Russian Federation | 432063 | |
| 682 | Novo Nordisk Investigational Site | Voronezh | Russian Federation | 394018 | |
| 683 | Novo Nordisk Investigational Site | Yaroslavl | Russian Federation | 150003 | |
| 684 | Novo Nordisk Investigational Site | Belgrade | Serbia | 11000 | |
| 685 | Novo Nordisk Investigational Site | Belgrade | Serbia | 11080 | |
| 686 | Novo Nordisk Investigational Site | Novi Sad | Serbia | 21000 | |
| 687 | Novo Nordisk Investigational Site | Port Elizabeth | Eastern Cape | South Africa | 6001 |
| 688 | Novo Nordisk Investigational Site | Bloemfontein | Free State | South Africa | 9301 |
| 689 | Novo Nordisk Investigational Site | Alberton | Gauteng | South Africa | 1450 |
| 690 | Novo Nordisk Investigational Site | Centurion | Gauteng | South Africa | 0157 |
| 691 | Novo Nordisk Investigational Site | Germiston | Gauteng | South Africa | 1401 |
| 692 | Novo Nordisk Investigational Site | Johannesburg | Gauteng | South Africa | 2013 |
| 693 | Novo Nordisk Investigational Site | Johannesburg | Gauteng | South Africa | 2157 |
| 694 | Novo Nordisk Investigational Site | Johannesburg | Gauteng | South Africa | 2193 |
| 695 | Novo Nordisk Investigational Site | Lenasia | Gauteng | South Africa | 1827 |
| 696 | Novo Nordisk Investigational Site | Pretoria | Gauteng | South Africa | 0183 |
| 697 | Novo Nordisk Investigational Site | Pretoria | Gauteng | South Africa | 0184 |
| 698 | Novo Nordisk Investigational Site | Pretoria | Gauteng | South Africa | 0186 |
| 699 | Novo Nordisk Investigational Site | Roodepoort | Gauteng | South Africa | 1724 |
| 700 | Novo Nordisk Investigational Site | Durban | KwaZulu-Natal | South Africa | 4091 |
| 701 | Novo Nordisk Investigational Site | Cape Town | Western Cape | South Africa | 7130 |
| 702 | Novo Nordisk Investigational Site | Cape Town | Western Cape | South Africa | 7405 |
| 703 | Novo Nordisk Investigational Site | Cape Town | Western Cape | South Africa | 7500 |
| 704 | Novo Nordisk Investigational Site | Cape Town | Western Cape | South Africa | 7700 |
| 705 | Novo Nordisk Investigational Site | Kuilsriver | Western Cape | South Africa | 7580 |
| 706 | Novo Nordisk Investigational Site | Paarl | Western Cape | South Africa | 7646 |
| 707 | Novo Nordisk Investigational Site | Worcester | Western Cape | South Africa | 6850 |
| 708 | Novo Nordisk Investigational Site | Almeria | Spain | 04009 | |
| 709 | Novo Nordisk Investigational Site | La Coruña | Spain | 15006 | |
| 710 | Novo Nordisk Investigational Site | Madrid | Spain | 28009 | |
| 711 | Novo Nordisk Investigational Site | Madrid | Spain | 28034 | |
| 712 | Novo Nordisk Investigational Site | Madrid | Spain | 28046 | |
| 713 | Novo Nordisk Investigational Site | Málaga | Spain | 29006 | |
| 714 | Novo Nordisk Investigational Site | Palma de Mallorca | Spain | 07198 | |
| 715 | Novo Nordisk Investigational Site | Sevilla | Spain | 41003 | |
| 716 | Novo Nordisk Investigational Site | Sevilla | Spain | 41009 | |
| 717 | Novo Nordisk Investigational Site | Sevilla | Spain | 41010 | |
| 718 | Novo Nordisk Investigational Site | Valencia | Spain | 46026 | |
| 719 | Novo Nordisk Investigational Site | Göteborg | Sweden | 413 45 | |
| 720 | Novo Nordisk Investigational Site | Kristianstad | Sweden | 291 85 | |
| 721 | Novo Nordisk Investigational Site | Lund | Sweden | 222 21 | |
| 722 | Novo Nordisk Investigational Site | Stockholm | Sweden | 171 64 | |
| 723 | Novo Nordisk Investigational Site | Örebro | Sweden | 701 85 | |
| 724 | Novo Nordisk Investigational Site | Östersund | Sweden | 831 83 | |
| 725 | Novo Nordisk Investigational Site | Hsinchu City | Taiwan | 300 | |
| 726 | Novo Nordisk Investigational Site | Kaohsiung City | Taiwan | 82445 | |
| 727 | Novo Nordisk Investigational Site | New Taipei City | Taiwan | 25160 | |
| 728 | Novo Nordisk Investigational Site | Taipei | Taiwan | 100 | |
| 729 | Novo Nordisk Investigational Site | Taoyuan City | Taiwan | 333 | |
| 730 | Novo Nordisk Investigational Site | Bangkok | Thailand | 10330 | |
| 731 | Novo Nordisk Investigational Site | Bangkok | Thailand | 10400 | |
| 732 | Novo Nordisk Investigational Site | Bangkok | Thailand | 10700 | |
| 733 | Novo Nordisk Investigational Site | Chiang Mai | Thailand | 50200 | |
| 734 | Novo Nordisk Investigational Site | Khon kaen | Thailand | 40002 | |
| 735 | Novo Nordisk Investigational Site | Klong Luang, Pathumthani | Thailand | 12120 | |
| 736 | Novo Nordisk Investigational Site | Adana | Turkey | 01250 | |
| 737 | Novo Nordisk Investigational Site | Adana | Turkey | 01330 | |
| 738 | Novo Nordisk Investigational Site | Ankara | Turkey | 06010 | |
| 739 | Novo Nordisk Investigational Site | Ankara | Turkey | 06100 | |
| 740 | Novo Nordisk Investigational Site | Antalya | Turkey | 07058 | |
| 741 | Novo Nordisk Investigational Site | Aydin | Turkey | 09010 | |
| 742 | Novo Nordisk Investigational Site | Eskisehir | Turkey | 26040 | |
| 743 | Novo Nordisk Investigational Site | Gaziantep | Turkey | 27070 | |
| 744 | Novo Nordisk Investigational Site | Istanbul | Turkey | 34010 | |
| 745 | Novo Nordisk Investigational Site | Istanbul | Turkey | 34098 | |
| 746 | Novo Nordisk Investigational Site | Istanbul | Turkey | 34371 | |
| 747 | Novo Nordisk Investigational Site | Istanbul | Turkey | 34390 | |
| 748 | Novo Nordisk Investigational Site | Istanbul | Turkey | 34400 | |
| 749 | Novo Nordisk Investigational Site | Istanbul | Turkey | 34752 | |
| 750 | Novo Nordisk Investigational Site | Istanbul | Turkey | 34760 | |
| 751 | Novo Nordisk Investigational Site | Istanbul | Turkey | 34899 | |
| 752 | Novo Nordisk Investigational Site | Izmir | Turkey | 35100 | |
| 753 | Novo Nordisk Investigational Site | Izmir | Turkey | 35180 | |
| 754 | Novo Nordisk Investigational Site | Izmir | Turkey | 35340 | |
| 755 | Novo Nordisk Investigational Site | Kayseri | Turkey | 38039 | |
| 756 | Novo Nordisk Investigational Site | Mersin | Turkey | 33343 | |
| 757 | Novo Nordisk Investigational Site | Sivas | Turkey | 58140 | |
| 758 | Novo Nordisk Investigational Site | Chernivtsi | Ukraine | 58000 | |
| 759 | Novo Nordisk Investigational Site | Kharkiv | Ukraine | 61002 | |
| 760 | Novo Nordisk Investigational Site | Kharkiv | Ukraine | 61039 | |
| 761 | Novo Nordisk Investigational Site | Kyiv | Ukraine | 01023 | |
| 762 | Novo Nordisk Investigational Site | Kyiv | Ukraine | 01135 | |
| 763 | Novo Nordisk Investigational Site | Kyiv | Ukraine | 02091 | |
| 764 | Novo Nordisk Investigational Site | Kyiv | Ukraine | 02660 | |
| 765 | Novo Nordisk Investigational Site | Kyiv | Ukraine | 03049 | |
| 766 | Novo Nordisk Investigational Site | Kyiv | Ukraine | 03151 | |
| 767 | Novo Nordisk Investigational Site | Kyiv | Ukraine | 04053 | |
| 768 | Novo Nordisk Investigational Site | Lviv | Ukraine | 79059 | |
| 769 | Novo Nordisk Investigational Site | Odesa | Ukraine | 65025 | |
| 770 | Novo Nordisk Investigational Site | Odesa | Ukraine | 65059 | |
| 771 | Novo Nordisk Investigational Site | Vinnytsia | Ukraine | 21000 | |
| 772 | Novo Nordisk Investigational Site | Vinnytsia | Ukraine | 21018 | |
| 773 | Novo Nordisk Investigational Site | Zhytomyr | Ukraine | 10002 | |
| 774 | Novo Nordisk Investigational Site | Addlestone | United Kingdom | KT15 2BH | |
| 775 | Novo Nordisk Investigational Site | Airdrie | United Kingdom | ML6 0JS | |
| 776 | Novo Nordisk Investigational Site | Antrim | United Kingdom | BT42 2RL | |
| 777 | Novo Nordisk Investigational Site | Axbridge | United Kingdom | BS26 2BJ | |
| 778 | Novo Nordisk Investigational Site | Basingstoke | United Kingdom | RG24 9GT | |
| 779 | Novo Nordisk Investigational Site | Bexhill-on-Sea | United Kingdom | TN40 1JJ | |
| 780 | Novo Nordisk Investigational Site | Birmingham | United Kingdom | B9 5SS | |
| 781 | Novo Nordisk Investigational Site | Blackpool | United Kingdom | FY3 7EN | |
| 782 | Novo Nordisk Investigational Site | Bollington | United Kingdom | SK10 5JH | |
| 783 | Novo Nordisk Investigational Site | Bradford-on-Avon | United Kingdom | BA15 1DQ | |
| 784 | Novo Nordisk Investigational Site | Bristol | United Kingdom | BS10 5NB | |
| 785 | Novo Nordisk Investigational Site | Cardiff | United Kingdom | CF5 4AD | |
| 786 | Novo Nordisk Investigational Site | Chertsey | United Kingdom | KT16 0PZ | |
| 787 | Novo Nordisk Investigational Site | Chester | United Kingdom | CH2 1UL | |
| 788 | Novo Nordisk Investigational Site | Coventry | United Kingdom | CV2 2DX | |
| 789 | Novo Nordisk Investigational Site | Denmark Hill, London | United Kingdom | SE5 9RS | |
| 790 | Novo Nordisk Investigational Site | Dundee | United Kingdom | DD1 9SY | |
| 791 | Novo Nordisk Investigational Site | Exeter | United Kingdom | EX2 5DW | |
| 792 | Novo Nordisk Investigational Site | Harrogate, North Yorkshire | United Kingdom | HG2 7SX | |
| 793 | Novo Nordisk Investigational Site | Harrow | United Kingdom | HA1 3UJ | |
| 794 | Novo Nordisk Investigational Site | High Wycombe | United Kingdom | HP11 2TT | |
| 795 | Novo Nordisk Investigational Site | Hull | United Kingdom | HU3 2JZ | |
| 796 | Novo Nordisk Investigational Site | Leicester | United Kingdom | LE3 9QP | |
| 797 | Novo Nordisk Investigational Site | Lincoln | United Kingdom | LN2 5QY | |
| 798 | Novo Nordisk Investigational Site | Liverpool | United Kingdom | L9 7AL | |
| 799 | Novo Nordisk Investigational Site | London | United Kingdom | SE1 9RT | |
| 800 | Novo Nordisk Investigational Site | London | United Kingdom | W12 0NN | |
| 801 | Novo Nordisk Investigational Site | Manchester | United Kingdom | M8 5RB | |
| 802 | Novo Nordisk Investigational Site | Middlesbrough | United Kingdom | TS4 3BW | |
| 803 | Novo Nordisk Investigational Site | Plymouth | United Kingdom | PL6 8DH | |
| 804 | Novo Nordisk Investigational Site | Rhyl | United Kingdom | LL18 1DA | |
| 805 | Novo Nordisk Investigational Site | Rotherham | United Kingdom | S65 1DA | |
| 806 | Novo Nordisk Investigational Site | Sandbach | United Kingdom | CW11 1EQ | |
| 807 | Novo Nordisk Investigational Site | Somerset | United Kingdom | BA21 4AT | |
| 808 | Novo Nordisk Investigational Site | Southampton | United Kingdom | SO30 3JB | |
| 809 | Novo Nordisk Investigational Site | Stevenage | United Kingdom | SG1 4AB | |
| 810 | Novo Nordisk Investigational Site | Sunderland | United Kingdom | SR4 7TP | |
| 811 | Novo Nordisk Investigational Site | Taunton | United Kingdom | TA1 5DA | |
| 812 | Novo Nordisk Investigational Site | Torquay | United Kingdom | TQ2 7AA | |
| 813 | Novo Nordisk Investigational Site | Truro | United Kingdom | TR1 3LJ | |
| 814 | Novo Nordisk Investigational Site | West Sussex | United Kingdom | PO19 6SE | |
| 815 | Novo Nordisk Investigational Site | Wishaw | United Kingdom | ML2 0DP |
Sponsors and Collaborators
- Novo Nordisk A/S
Investigators
- Study Director: Clinical Reporting Anchor and Disclosure (1452), Novo Nordisk A/S
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
Novo Nordisk A/S
ClinicalTrials.gov Identifier:
NCT03574597
Other Study ID Numbers:
- EX9536-4388
- 2017-003380-35
- U1111-1200-5564
First Posted:
Jul 2, 2018
Last Update Posted:
Mar 21, 2022
Last Verified:
Mar 1, 2022
Individual Participant Data (IPD) Sharing Statement:
Yes
Plan to Share IPD:
Yes
Studies a U.S. FDA-regulated Drug Product:
Yes
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms: