Antioxidants Vitamins and Muscle Damage
Study Details
Study Description
Brief Summary
Determine if acute supplementation with antioxidant vitamins (vitamin C and vitamin E) influences the muscle damage and fatigue caused after an acute session of eccentric training.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
N/A |
Detailed Description
A randomized, single-blind, placebo-control parallel trial will be conducted. In a previous session volunteers will be interviewed to determine if they meet the inclusion criteria.
Participants should avoid ingesting of foods that contain high amounts of antioxidant compounds: more than two juices of fruits, more than four cups of coffee or tea. Juices with high antioxidant content should be avoided. Alcoholic beverages should also be avoided. Participants will be divided in to groups and will performance one resistance exercise sessions. Prior to exercise, one group will intake supplementation VitC (1000 mg) + VitE (235 mg) and the other supplementation with placebo.
The following sequence will be performed in each session: 1) baseline assessment (analysis of the composition body, blood draw and parameters of performance) prior to exercise session ; 2) administration of vitamin or placebo supplementation 2 hours before exercise session ; 3) post-exercise assessments (blood biomarkers and performance parameters) immediately after the session and after 24 hours. DOMS will also be assessed 48 h and 72 h after training. The training session implemented will be designed by a Sport Scientific
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Experimental: Supplementation Vitamin C and Vitamin E before exercise |
Dietary Supplement: Dietary Supplement: Vitamin C and vitamin E
Antioxidant supplementation
Other Names:
|
| Placebo Comparator: Placebo Placebo before exercise |
Dietary Supplement: Placebo
Placebo administration
|
Outcome Measures
Primary Outcome Measures
- Percentage of body fat and muscle mass [Prior to the intervention]
Determination of body composition using skinfolds measurements
- DOMS [0 hours post exercise]
Delayed onset muscle soreness. This outcome will be measure with a 10-point visual analogic scale (0= no pain; 10 = worst possible pain)
- DOMS [24 hours post exercise]
Delayed onset muscle soreness. This outcome will be measure with a 10-point visual analogic scale (0= no pain; 10 = worst possible pain)
- Blood malondialdehyde (MDA) [2 hours prior to exercise]
MDA will be analyzed from a blood sample
- Blood creatine quinase (CK) [2 hours prior to exercise]
CK will be analyzed from a blood sample
- Blood malondialdehyde (MDA) [Inmediatly after exercise]
MDA will be analyzed from a blood sample
- Blood malondialdehyde (MDA) [24 hours after exercise]
MDA will be analyzed from a blood sample
- Blood creatine quinase (CK) [24 hours after exercise]
CK will be analyzed from a blood sample
- Jump height in a Counter Movement Jump [2 hours prior to exercise]
Jump height (cm) in a counter movement jump measured with Octojump Platform
- Jump height in a Counter Movement Jump [Inmediatly after exercise]
Jump height (cm) in a counter movement jump measured with Octojump Platform
- Jump height in a Counter Movement Jump [24 h after exercise]
Jump height (cm) in a counter movement jump measured with Octojump Platform
- Jump Height in a Squat Jump [24 h after exercise]
Jump Height (cm) in a Squat Jump measured with Octojump Platform
- Jump Height in a Squat Jump [Inmediately after exercise]
Jump Height (cm) in a Squat Jump measured with Octojump Platform
- Jump Height in a squat Jump [2 hours prior to exercise]
Jump height (cm) in a squat jump with Octojump Platform measured with Octojump Platform
- Jump Height in a Drop Jump [2 hours prior to exercise]
Jump height (cm) was measured in different drop jumps with Octojump Platform
- Jump Height in a Drop Jump [Inmediately after exercise]
Jump height (cm) was measured in different drop jumps with Octojump Platform
- Contact time in a Drop Jump [Inmediately after exercise]
Contact time (s)measured in different drop jumps with Octojump Platform
- Jump Height in a Drop Jump [Inmediately after exercise]
Jump height (cm) measured in different drop jumps with Octojump Platform
- Contact time in a Drop Jump [24 hours after exercise]
Contact time (s) measured in different drop jumps with Octojump Platform
- Jump Height in a Drop Jump [24 hours after exercise]
Jump height (cm) measured in different drop jumps with Octojump Platform
- Contact time in a Drop Jump [Inmediately after exercise]
Capillary blood lactate evaluated with Lactate Pro 2
- Concentration of blood lactate [2 hours before exercise]
Capillary blood lactate with Lactate Pro 2
Eligibility Criteria
Criteria
Inclusion Criteria:
-
Healthy
-
Physically active
Exclusion Criteria:
-
Injuries
-
Supplementation or drugs
-
Smokers
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Universidad Europea de Madrid | Madrid | Spain |
Sponsors and Collaborators
- Universidad Europea de Madrid
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- CIPI/20/209-part2