Gemcitabine Hydrochloride With or Without Erlotinib Hydrochloride Followed by the Same Chemotherapy Regimen With or Without Radiation Therapy and Capecitabine or Fluorouracil in Treating Patients With Pancreatic Cancer That Has Been Removed by Surgery
Sponsor
National Cancer Institute (NCI) (NIH)
Overall Status
Active, not recruiting
CT.gov ID
NCT01013649
Collaborator
NRG Oncology (Other)
545
698
4
157.4
0.8
0
Study Details
Study Description
Brief Summary
This randomized phase II-R/III trial studies gemcitabine hydrochloride with or without erlotinib hydrochloride followed by the same chemotherapy regimen with or without radiation therapy and capecitabine or fluorouracil in treating patients with pancreatic cancer that was removed by surgery. Drugs used in chemotherapy, such as gemcitabine hydrochloride, capecitabine, and fluorouracil, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Erlotinib hydrochloride may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Radiation therapy uses high energy x-rays to kill tumor cells. Giving chemotherapy together with or without erlotinib hydrochloride and/or radiation therapy after surgery may kill any tumor cells that remain after surgery. It is not yet known whether chemotherapy is more effective when given with or without erlotinib hydrochloride and/or radiation therapy in treating pancreatic cancer.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
|
Phase 3 |
Detailed Description
PRIMARY OBJECTIVES:
- To determine whether the addition of erlotinib (erlotinib hydrochloride) to gemcitabine (gemcitabine hydrochloride) adjuvant chemotherapy shows a signal for improved survival as compared to gemcitabine alone following R0 or R1 resection of head of pancreas adenocarcinoma (including adenocarcinoma of the head, neck, and uncinate process). (Phase II-R) II. To determine whether the use of concurrent fluoropyrimidine and radiotherapy following adjuvant gemcitabine based chemotherapy or non-gemcitabine based chemotherapy such as modified fluorouracil-leucovorin-irinotecan-oxaliplatin regimen (FOLFIRINOX) further enhances survival for such patients who are without evidence of progressive disease after 5 months of adjuvant chemotherapy. (Phase III)
SECONDARY OBJECTIVES:
-
To evaluate disease-free survival of adjuvant chemotherapy followed by radiotherapy and concurrent fluoropyrimidine for patients with resected head of pancreas adenocarcinoma who are disease free after 5 months of adjuvant chemotherapy.
-
To evaluate disease-free survival of standard adjuvant gemcitabine chemotherapy with and without erlotinib for patients with resected head of pancreas adenocarcinoma.
-
To evaluate adverse events with and without erlotinib for patients with resected head of pancreas adenocarcinoma.
-
To evaluate adverse events of adjuvant chemotherapy with or without radiation therapy and concurrent fluoropyrimidine for patients with resected head of pancreas adenocarcinoma who are disease free after adjuvant chemotherapy.
-
To evaluate preoperative cross-sectional imaging of the primary head of pancreas adenocarcinoma in order to determine the frequency with which objective criteria of resectability are present.
-
To determine if patients reporting low baseline fatigue, as measured by the Functional Assessment of Chronic Illness Therapy (FACIT)-Fatigue, predicts survival and to explore correlations between baseline fatigue, as measured by Patient-Reported Outcomes Measurement Information System (PROMIS), and survival.
OUTLINE: Patients without disease progression after treatment in arm I or II are randomized to 1 of 2 additional treatment arms (arm III or IV).
ARM I: Patients receive either gemcitabine hydrochloride or allowable combination chemotherapy per standard of care for 5 months.
ARM II (closed to accrual 4/2/14): Patients receive gemcitabine hydrochloride intravenously (IV) over 30 minutes on days 1, 8, and 15 and erlotinib hydrochloride orally (PO) once daily on days 1-28. Treatment repeats every 28 days for up to 5 courses in the absence of disease progression or unacceptable toxicity.
ARM III: Patients receive the same treatment as in arm I for 1 month.
ARM IV: Patients receive the same treatment as in arm I for 1 month. Beginning within 7-21 days after completion of chemotherapy, patients undergo radiotherapy (3-dimensional conformal radiotherapy or intensity-modulated radiotherapy) 5 days per week for 5.5 weeks (28 fractions). During radiotherapy, patients receive either capecitabine PO twice daily (BID) 5 days per week or fluorouracil IV continuously for 5.5 weeks or until radiotherapy is completed.
After completion of study treatment, patients are followed up periodically.
Study Design
Study Type:
Interventional
Anticipated Enrollment
:
545 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Masking:
None (Open Label)
Primary Purpose:
Treatment
Official Title:
A Phase II-R and a Phase III Trial Evaluating Both Erlotinib (Ph II-R) and Chemoradiation (Ph III) as Adjuvant Treatment for Patients With Resected Head of Pancreas Adenocarcinoma
Actual Study Start Date
:
Nov 17, 2009
Anticipated Primary Completion Date
:
Dec 31, 2022
Anticipated Study Completion Date
:
Dec 31, 2022
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Active Comparator: Arm I (gemcitabine hydrochloride or combination chemotherapy) Patients receive either gemcitabine hydrochloride or allowable combination chemotherapy per standard of care for 5 months. |
Drug: Chemotherapy
Given combination chemotherapy
Other Names:
Drug: Gemcitabine Hydrochloride
Given IV
Other Names:
Other: Laboratory Biomarker Analysis
Correlative studies
Other: Quality-of-Life Assessment
Ancillary studies
Other Names:
|
| Experimental: Arm II (gemcitabine hydrochloride, erlotinib hydrochloride) Patients receive gemcitabine hydrochloride IV over 30 minutes on days 1, 8, and 15 and erlotinib hydrochloride PO once daily on days 1-28. Treatment repeats every 28 days for up to 5 courses in the absence of disease progression or unacceptable toxicity. (closed to accrual 4/2/14) |
Drug: Erlotinib Hydrochloride
Given PO
Other Names:
Drug: Gemcitabine Hydrochloride
Given IV
Other Names:
Other: Laboratory Biomarker Analysis
Correlative studies
Other: Quality-of-Life Assessment
Ancillary studies
Other Names:
|
| Experimental: Arm III (chemotherapy) Patients receive the same treatment as in arm I for 1 month. |
Drug: Chemotherapy
Given combination chemotherapy
Other Names:
Drug: Gemcitabine Hydrochloride
Given IV
Other Names:
Other: Laboratory Biomarker Analysis
Correlative studies
Other: Quality-of-Life Assessment
Ancillary studies
Other Names:
|
| Experimental: Arm IV (chemotherapy, chemoradiotherapy) Patients receive the same treatment as in arm I for 1 month. Beginning within 7-21 days after completion of chemotherapy, patients undergo radiotherapy (3-dimensional conformal radiotherapy or intensity-modulated radiotherapy) 5 days per week for 5.5 weeks (28 fractions). During radiotherapy, patients receive either capecitabine PO BID 5 days per week or fluorouracil IV continuously for 5.5 weeks or until radiotherapy is completed. |
Radiation: 3-Dimensional Conformal Radiation Therapy
Undergo 3-dimensional conformal radiation therapy
Other Names:
Drug: Capecitabine
Given PO
Other Names:
Drug: Chemotherapy
Given combination chemotherapy
Other Names:
Drug: Fluorouracil
Given IV
Other Names:
Drug: Gemcitabine Hydrochloride
Given IV
Other Names:
Radiation: Intensity-Modulated Radiation Therapy
Undergo intensity-modulated radiation therapy
Other Names:
Other: Laboratory Biomarker Analysis
Correlative studies
Other: Quality-of-Life Assessment
Ancillary studies
Other Names:
|
Outcome Measures
Primary Outcome Measures
- Overall survival (Phase II) [From the date of first randomization (gemcitabine vs. gemcitabine/erlotinib) to the date of death or last follow-up, assessed up to 11 years]
Overall survival will be estimated by the Kaplan-Meier method. The distribution of overall survival estimates between the two arms for both primary endpoint questions will be compared using the log rank test. The Cox proportional hazard regression model will be used to analyze the effects of factors, in addition to treatment, that may be associated with overall survival.
- Overall survival (Phase III) [From the date of second randomization (chemotherapy vs. chemotherapy followed by chemoradiation) to the date of death or last follow-up, assessed up to 11 years]
Overall survival will be estimated by the Kaplan-Meier method. The distribution of overall survival estimates between the two arms for both primary endpoint questions will be compared using the log rank test. The Cox proportional hazard regression model will be used to analyze the effects of factors, in addition to treatment, that may be associated with overall survival.
Secondary Outcome Measures
- Disease-free survival [Up to 11 years]
Disease-free survival will be estimated by the Kaplan-Meier method.
- Incidence of adverse events assessed according to National Cancer Institute Common Terminology Criteria for Adverse Events (CTCAE) version 4.0 (CTCAE version 5.0 will be used starting April 1, 2018) [Up to 11 years]
- Frequency of objective criteria of resectability as measured by preoperative imaging [Up to 11 years]
- Changes in fatigue as measured by the Functional Assessment of Chronic Illness Therapy-Fatigue (primary) and the Patient-Reported Outcomes Measurement Information System derived short form (exploratory) [Baseline up to 24 months]
The primary health-related quality of life hypothesis will be tested using the log-rank statistic with a significance level of 0.05. Additionally, analyses of fatigue effect will be performed using the Cox proportional hazard model.
Eligibility Criteria
Criteria
Ages Eligible for Study:
18 Years
and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
-
Histologic proof of primary head of pancreas invasive adenocarcinoma managed with a potentially curative resection (i.e., removal of all gross tumor) involving a classic pancreaticoduodenectomy (Whipple) or a pylorus preserving pancreaticoduodenectomy; patients with invasive adenocarcinoma that also contains a component of intraductal papillary mucinous neoplasm (IPMN) are eligible
-
The operating surgeon must document in the operative note that a complete gross excision of the primary tumor was achieved; the pathology report must include documentation of the margin status and the size of the tumor; the pathology report must also include the status of the three major margins-bile duct, pancreatic parenchyma, and retroperitoneal (uncinate)
-
For patients who have not started their chemotherapy prior to registration, the interval between definitive tumor-related surgery and 1st step registration must be between 21-70 days; for patients entering on the study who have already received up to 3 months of adjuvant chemotherapy as per the treating institution, the interval between definitive tumor-related surgery and day one of adjuvant chemotherapy must be between 21-77 days
-
Patients will be staged according to the 6th edition American Joint Committee on Cancer (AJCC) staging system with pathologic stage T1-3, N0-1, M-0 being eligible
-
Zubrod performance status 0 or 1
-
Complete history and physical examination including weight and Zubrod status within 31 days of study entry (or within 31 days prior to day 1 of chemotherapy post-surgery for those patients having started chemotherapy prior to first step registration)
-
Before starting therapy the patient should be able to maintain adequate oral nutrition of >= 1500 calories estimated caloric intake per day and be free of significant nausea and vomiting
-
Complete blood count (CBC)/differential obtained within 21 days of registration on study (or within 21 days prior to day 1 of chemotherapy post-surgery for those patients having started chemotherapy prior to first step registration)
-
Absolute neutrophil count (ANC) >= 1,500/mm^3
-
Platelets >= 100,000/mm^3
-
Hemoglobin (Hgb) >= 8.0 g/dL (transfusion or other intervention to achieve Hgb >= 8.0 g/dl is acceptable)
-
Post resection serum cancer antigen (CA)19-9 =< 180 units/mL AND prior to any systemic treatment
-
Serum total bilirubin =< twice the institutional upper limit of normal (ULN) within 21 days of registration on study (or within 21 days prior to day 1 of chemotherapy post-surgery for those patients having started chemotherapy prior to first step registration)
-
Creatinine levels =< twice the institutional upper limit of normal within 21 days of registration on study (or within 21 days prior to day 1 of chemotherapy post-surgery for those patients having started chemotherapy prior to first step registration)
-
Serum glutamic oxaloacetic transaminase (SGOT) must be =< 2.5 x institutional ULN within 21 days of registration on study (or within 21 days prior to day 1 of chemotherapy post-surgery for those patients having started chemotherapy prior to first step registration)
-
Negative serum pregnancy test for women of childbearing potential within 14 days of study registration
-
Abdominal/pelvic computed tomography (CT) scan with contrast is preferred; abdominal CT alone is acceptable only if insurance restrictions are experienced; chest CT/x-ray (CT of chest preferred) within 31 days of registration on study (or within 31 days prior to day 1 of chemo post-surgery for those patients having started chemotherapy prior to first step registration); patients allergic to intravenous (IV) contrast can have magnetic resonance imaging (MRI) of the abdomen/pelvis instead
-
Signed study-specific informed consent
-
Consultation, agreement, and documentation in the patient's chart by a radiation oncologist that patient is suitable to receive radiotherapy per this protocol
-
Women of childbearing potential and male participants must practice adequate contraception
-
Patients with active human immunodeficiency virus (HIV) infection are eligible if their cluster of differentiation (CD)4 count is > 499/cu mm and their viral load is < 50 copies/ml; use of highly active antiretroviral treatment (HAART) is allowed
Exclusion Criteria:
-
Patients with non-adenocarcinomas, adenosquamous carcinomas, islet cell (neuroendocrine) tumors, cystadenomas, cystadenocarcinomas, carcinoid tumors, duodenal carcinomas, distal bile duct, and ampullary carcinomas; patients with tumors that are largely IPMN with a minimal or minor component of invasive carcinoma are not eligible; patients with acinar carcinomas are not eligible; patients with IPMN's that contain some secondary (minor) foci of adenocarcinoma are also not eligible
-
Patients managed with a total pancreatectomy, a distal pancreatectomy, or central pancreatectomy
-
Patients entering on the study after pancreaticoduodenectomy, who have not already started chemotherapy must not have had prior systemic chemotherapy for pancreas cancer; note that prior chemotherapy for a different cancer is allowable; for patients entering on the study who have already received up to 3 months of adjuvant chemotherapy as per the treating institution, patients must not have received adjuvant chemotherapy with agents other than gemcitabine, nab-paclitaxel, oxaliplatin, fluoropyrimidine, or irinotecan for the current pancreatic cancer; prior chemotherapy for a different cancer is allowable
-
Prior radiotherapy to the region of the study cancer that would result in overlap of radiation therapy fields
-
Previous history of invasive malignancy (except non-melanoma skin cancer) unless the patient has been disease free for at least 2 years prior to study entry (or first day of chemotherapy for patients having started chemotherapy prior to first step registration); patients with a previous history of carcinoma in situ are eligible
-
Severe, active co-morbidity, defined as follows per time points indicated below (or per time points indicated below prior to the first day of chemotherapy for patients having started chemotherapy prior to first step registration):
-
Unstable angina and/or congestive heart failure requiring hospitalization within the last 6 months
-
Transmural myocardial infarction within the 3 months of study registration
-
Acute bacterial or fungal infection requiring intravenous antibiotics at the time of registration
-
Chronic obstructive pulmonary disease exacerbation or other respiratory illness requiring hospitalization or precluding study therapy at the time of registration
-
Pregnant or lactating women
-
Women of childbearing potential and men who are sexually active and not willing/able to use medically acceptable forms of contraception
-
If surgical margin status cannot be determined after consultation with the operating surgeon and the institutional pathologist, the patient will be ineligible
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Providence Hospital | Mobile | Alabama | United States | 36608 |
| 2 | Alaska Breast Care and Surgery LLC | Anchorage | Alaska | United States | 99508 |
| 3 | Alaska Women's Cancer Care | Anchorage | Alaska | United States | 99508 |
| 4 | Katmai Oncology Group | Anchorage | Alaska | United States | 99508 |
| 5 | Providence Alaska Medical Center | Anchorage | Alaska | United States | 99508 |
| 6 | Sutter Cancer Centers Radiation Oncology Services-Auburn | Auburn | California | United States | 95603 |
| 7 | Providence Saint Joseph Medical Center/Disney Family Cancer Center | Burbank | California | United States | 91505 |
| 8 | Mills-Peninsula Medical Center | Burlingame | California | United States | 94010 |
| 9 | Sutter Cancer Centers Radiation Oncology Services-Cameron Park | Cameron Park | California | United States | 95682 |
| 10 | Mercy San Juan Medical Center | Carmichael | California | United States | 95608 |
| 11 | East Bay Radiation Oncology Center | Castro Valley | California | United States | 94546 |
| 12 | Community Cancer Institute | Clovis | California | United States | 93611 |
| 13 | City of Hope Comprehensive Cancer Center | Duarte | California | United States | 91010 |
| 14 | Epic Care-Dublin | Dublin | California | United States | 94568 |
| 15 | Bay Area Breast Surgeons Inc | Emeryville | California | United States | 94608 |
| 16 | Epic Care Partners in Cancer Care | Emeryville | California | United States | 94608 |
| 17 | Kaiser Permanente-Fremont | Fremont | California | United States | 94538 |
| 18 | Fresno Cancer Center | Fresno | California | United States | 93720 |
| 19 | Saint Agnes Medical Center | Fresno | California | United States | 93720 |
| 20 | Marin General Hospital | Greenbrae | California | United States | 94904 |
| 21 | UC San Diego Moores Cancer Center | La Jolla | California | United States | 92093 |
| 22 | Kaiser Permanente Los Angeles Medical Center | Los Angeles | California | United States | 90027 |
| 23 | Los Angeles County-USC Medical Center | Los Angeles | California | United States | 90033 |
| 24 | USC / Norris Comprehensive Cancer Center | Los Angeles | California | United States | 90033 |
| 25 | Cedars Sinai Medical Center | Los Angeles | California | United States | 90048 |
| 26 | Contra Costa Regional Medical Center | Martinez | California | United States | 94553-3156 |
| 27 | Memorial Medical Center | Modesto | California | United States | 95355 |
| 28 | Kaiser Permanente-Modesto | Modesto | California | United States | 95356 |
| 29 | El Camino Hospital | Mountain View | California | United States | 94040 |
| 30 | Highland General Hospital | Oakland | California | United States | 94602 |
| 31 | Alta Bates Summit Medical Center - Summit Campus | Oakland | California | United States | 94609 |
| 32 | Bay Area Tumor Institute | Oakland | California | United States | 94609 |
| 33 | Hematology and Oncology Associates-Oakland | Oakland | California | United States | 94609 |
| 34 | Kaiser Permanente Oakland-Broadway | Oakland | California | United States | 94611 |
| 35 | Kaiser Permanente-Oakland | Oakland | California | United States | 94611 |
| 36 | UC Irvine Health/Chao Family Comprehensive Cancer Center | Orange | California | United States | 92868 |
| 37 | Palo Alto Medical Foundation Health Care | Palo Alto | California | United States | 94301 |
| 38 | Valley Medical Oncology Consultants | Pleasanton | California | United States | 94588 |
| 39 | Kaiser Permanente-Rancho Cordova Cancer Center | Rancho Cordova | California | United States | 95670 |
| 40 | Kaiser Permanente-Redwood City | Redwood City | California | United States | 94063 |
| 41 | Kaiser Permanente-Richmond | Richmond | California | United States | 94801 |
| 42 | Rohnert Park Cancer Center | Rohnert Park | California | United States | 94928 |
| 43 | Kaiser Permanente-Roseville | Roseville | California | United States | 95661 |
| 44 | Sutter Cancer Centers Radiation Oncology Services-Roseville | Roseville | California | United States | 95661 |
| 45 | The Permanente Medical Group-Roseville Radiation Oncology | Roseville | California | United States | 95678 |
| 46 | Sutter Medical Center Sacramento | Sacramento | California | United States | 95816 |
| 47 | Mercy General Hospital Radiation Oncology Center | Sacramento | California | United States | 95819 |
| 48 | Kaiser Permanente-South Sacramento | Sacramento | California | United States | 95823 |
| 49 | South Sacramento Cancer Center | Sacramento | California | United States | 95823 |
| 50 | Kaiser Permanente - Sacramento | Sacramento | California | United States | 95825 |
| 51 | Saint Helena Hospital | Saint Helena | California | United States | 94574 |
| 52 | UC San Diego Medical Center - Hillcrest | San Diego | California | United States | 92103 |
| 53 | Sharp Memorial Hospital | San Diego | California | United States | 92123 |
| 54 | California Pacific Medical Center-Pacific Campus | San Francisco | California | United States | 94115 |
| 55 | Kaiser Permanente-San Francisco | San Francisco | California | United States | 94115 |
| 56 | Kaiser Permanente-Santa Teresa-San Jose | San Jose | California | United States | 95119 |
| 57 | Kaiser Permanente San Leandro | San Leandro | California | United States | 94577 |
| 58 | Doctors Medical Center- JC Robinson Regional Cancer Center | San Pablo | California | United States | 94806 |
| 59 | Kaiser Permanente-San Rafael | San Rafael | California | United States | 94903 |
| 60 | Kaiser Permanente Medical Center - Santa Clara | Santa Clara | California | United States | 95051 |
| 61 | Kaiser Permanente-Santa Rosa | Santa Rosa | California | United States | 95403 |
| 62 | Kaiser Permanente Cancer Treatment Center | South San Francisco | California | United States | 94080 |
| 63 | Kaiser Permanente-South San Francisco | South San Francisco | California | United States | 94080 |
| 64 | Kaiser Permanente-Stockton | Stockton | California | United States | 95210 |
| 65 | Palo Alto Medical Foundation-Sunnyvale | Sunnyvale | California | United States | 94086 |
| 66 | Sutter Cancer Centers Radiation Oncology Services-Vacaville | Vacaville | California | United States | 95687 |
| 67 | Kaiser Permanente-Vallejo | Vallejo | California | United States | 94589 |
| 68 | Sutter Solano Medical Center/Cancer Center | Vallejo | California | United States | 94589 |
| 69 | Kaiser Permanente-Walnut Creek | Walnut Creek | California | United States | 94596 |
| 70 | Rocky Mountain Cancer Centers-Aurora | Aurora | Colorado | United States | 80012 |
| 71 | The Medical Center of Aurora | Aurora | Colorado | United States | 80012 |
| 72 | University of Colorado Hospital | Aurora | Colorado | United States | 80045 |
| 73 | Boulder Community Hospital | Boulder | Colorado | United States | 80301 |
| 74 | Rocky Mountain Cancer Centers-Boulder | Boulder | Colorado | United States | 80304 |
| 75 | Penrose-Saint Francis Healthcare | Colorado Springs | Colorado | United States | 80907 |
| 76 | Rocky Mountain Cancer Centers-Penrose | Colorado Springs | Colorado | United States | 80907 |
| 77 | UCHealth Memorial Hospital Central | Colorado Springs | Colorado | United States | 80909 |
| 78 | Porter Adventist Hospital | Denver | Colorado | United States | 80210 |
| 79 | Colorado Blood Cancer Institute | Denver | Colorado | United States | 80218 |
| 80 | Presbyterian - Saint Lukes Medical Center - Health One | Denver | Colorado | United States | 80218 |
| 81 | Rocky Mountain Cancer Centers-Midtown | Denver | Colorado | United States | 80218 |
| 82 | SCL Health Saint Joseph Hospital | Denver | Colorado | United States | 80218 |
| 83 | Rocky Mountain Cancer Centers-Rose | Denver | Colorado | United States | 80220 |
| 84 | Rose Medical Center | Denver | Colorado | United States | 80220 |
| 85 | Western States Cancer Research NCORP | Denver | Colorado | United States | 80222 |
| 86 | Mercy Medical Center | Durango | Colorado | United States | 81301 |
| 87 | Mountain Blue Cancer Care Center - Swedish | Englewood | Colorado | United States | 80113 |
| 88 | Swedish Medical Center | Englewood | Colorado | United States | 80113 |
| 89 | Poudre Valley Hospital | Fort Collins | Colorado | United States | 80524 |
| 90 | Mountain Blue Cancer Care Center | Golden | Colorado | United States | 80401 |
| 91 | Saint Mary's Hospital and Regional Medical Center | Grand Junction | Colorado | United States | 81501 |
| 92 | North Colorado Medical Center | Greeley | Colorado | United States | 80631 |
| 93 | Rocky Mountain Cancer Centers-Greenwood Village | Greenwood Village | Colorado | United States | 80111 |
| 94 | Rocky Mountain Cancer Centers-Lakewood | Lakewood | Colorado | United States | 80228 |
| 95 | Saint Anthony Hospital | Lakewood | Colorado | United States | 80228 |
| 96 | Rocky Mountain Cancer Centers-Littleton | Littleton | Colorado | United States | 80120 |
| 97 | Littleton Adventist Hospital | Littleton | Colorado | United States | 80122 |
| 98 | Rocky Mountain Cancer Centers-Sky Ridge | Lone Tree | Colorado | United States | 80124 |
| 99 | Sky Ridge Medical Center | Lone Tree | Colorado | United States | 80124 |
| 100 | Longmont United Hospital | Longmont | Colorado | United States | 80501 |
| 101 | Rocky Mountain Cancer Centers-Longmont | Longmont | Colorado | United States | 80501 |
| 102 | McKee Medical Center | Loveland | Colorado | United States | 80539 |
| 103 | Parker Adventist Hospital | Parker | Colorado | United States | 80138 |
| 104 | Rocky Mountain Cancer Centers-Parker | Parker | Colorado | United States | 80138 |
| 105 | Saint Mary Corwin Medical Center | Pueblo | Colorado | United States | 81004 |
| 106 | Rocky Mountain Cancer Centers - Pueblo | Pueblo | Colorado | United States | 81008 |
| 107 | North Suburban Medical Center | Thornton | Colorado | United States | 80229 |
| 108 | Rocky Mountain Cancer Centers-Thornton | Thornton | Colorado | United States | 80260 |
| 109 | SCL Health Lutheran Medical Center | Wheat Ridge | Colorado | United States | 80033 |
| 110 | Hartford HealthCare - Saint Vincent's Medical Center | Bridgeport | Connecticut | United States | 06606 |
| 111 | Hartford Hospital | Hartford | Connecticut | United States | 06102 |
| 112 | Midstate Medical Center | Meriden | Connecticut | United States | 06451 |
| 113 | The Hospital of Central Connecticut | New Britain | Connecticut | United States | 06050 |
| 114 | Eastern Connecticut Hematology and Oncology Associates | Norwich | Connecticut | United States | 06360 |
| 115 | William Backus Hospital | Norwich | Connecticut | United States | 06360 |
| 116 | Beebe Medical Center | Lewes | Delaware | United States | 19958 |
| 117 | Christiana Gynecologic Oncology LLC | Newark | Delaware | United States | 19713 |
| 118 | Delaware Clinical and Laboratory Physicians PA | Newark | Delaware | United States | 19713 |
| 119 | Helen F Graham Cancer Center | Newark | Delaware | United States | 19713 |
| 120 | Medical Oncology Hematology Consultants PA | Newark | Delaware | United States | 19713 |
| 121 | Christiana Care Health System-Christiana Hospital | Newark | Delaware | United States | 19718 |
| 122 | Beebe Health Campus | Rehoboth Beach | Delaware | United States | 19971 |
| 123 | TidalHealth Nanticoke / Allen Cancer Center | Seaford | Delaware | United States | 19973 |
| 124 | Christiana Care Health System-Wilmington Hospital | Wilmington | Delaware | United States | 19801 |
| 125 | MedStar Georgetown University Hospital | Washington | District of Columbia | United States | 20007 |
| 126 | MedStar Washington Hospital Center | Washington | District of Columbia | United States | 20010 |
| 127 | UM Sylvester Comprehensive Cancer Center at Coral Gables | Coral Gables | Florida | United States | 33146 |
| 128 | UM Sylvester Comprehensive Cancer Center at Deerfield Beach | Deerfield Beach | Florida | United States | 33442 |
| 129 | Holy Cross Hospital | Fort Lauderdale | Florida | United States | 33308 |
| 130 | University of Florida Health Science Center - Gainesville | Gainesville | Florida | United States | 32610 |
| 131 | Mayo Clinic in Florida | Jacksonville | Florida | United States | 32224-9980 |
| 132 | Jupiter Medical Center | Jupiter | Florida | United States | 33458 |
| 133 | Mount Sinai Medical Center | Miami Beach | Florida | United States | 33140 |
| 134 | Jackson Memorial Hospital-Holtz Children's Hospital | Miami | Florida | United States | 33136 |
| 135 | University of Miami Miller School of Medicine-Sylvester Cancer Center | Miami | Florida | United States | 33136 |
| 136 | AdventHealth Orlando | Orlando | Florida | United States | 32803 |
| 137 | Orlando Health Cancer Institute | Orlando | Florida | United States | 32806 |
| 138 | Bay Medical Center | Panama City | Florida | United States | 32401 |
| 139 | Florida Cancer Affiliates | Trinity | Florida | United States | 34655 |
| 140 | Grady Health System | Atlanta | Georgia | United States | 30303 |
| 141 | Emory University Hospital Midtown | Atlanta | Georgia | United States | 30308 |
| 142 | Emory University Hospital/Winship Cancer Institute | Atlanta | Georgia | United States | 30322 |
| 143 | Emory Saint Joseph's Hospital | Atlanta | Georgia | United States | 30342 |
| 144 | John B Amos Cancer Center | Columbus | Georgia | United States | 31904 |
| 145 | Northeast Georgia Medical Center-Gainesville | Gainesville | Georgia | United States | 30501 |
| 146 | Memorial Health University Medical Center | Savannah | Georgia | United States | 31404 |
| 147 | Lewis Cancer and Research Pavilion at Saint Joseph's/Candler | Savannah | Georgia | United States | 31405 |
| 148 | The Cancer Center of Hawaii-Pali Momi | 'Aiea | Hawaii | United States | 96701 |
| 149 | Queen's Medical Center | Honolulu | Hawaii | United States | 96813 |
| 150 | University of Hawaii Cancer Center | Honolulu | Hawaii | United States | 96813 |
| 151 | Hawaii Cancer Care Inc-Liliha | Honolulu | Hawaii | United States | 96817 |
| 152 | The Cancer Center of Hawaii-Liliha | Honolulu | Hawaii | United States | 96817 |
| 153 | Kaiser Permanente Moanalua Medical Center | Honolulu | Hawaii | United States | 96819 |
| 154 | Saint Luke's Cancer Institute - Boise | Boise | Idaho | United States | 83712 |
| 155 | Saint Luke's Cancer Institute - Fruitland | Fruitland | Idaho | United States | 83619 |
| 156 | Saint Joseph Regional Medical Center | Lewiston | Idaho | United States | 83501 |
| 157 | Saint Luke's Cancer Institute - Meridian | Meridian | Idaho | United States | 83642 |
| 158 | Saint Luke's Cancer Institute - Nampa | Nampa | Idaho | United States | 83686 |
| 159 | Kootenai Clinic Cancer Services - Post Falls | Post Falls | Idaho | United States | 83854 |
| 160 | Saint Luke's Cancer Institute - Twin Falls | Twin Falls | Idaho | United States | 83301 |
| 161 | Saint Anthony's Health | Alton | Illinois | United States | 62002 |
| 162 | Northwest Community Hospital | Arlington Heights | Illinois | United States | 60005 |
| 163 | Rush - Copley Medical Center | Aurora | Illinois | United States | 60504 |
| 164 | Saint Joseph Medical Center | Bloomington | Illinois | United States | 61701 |
| 165 | Illinois CancerCare-Bloomington | Bloomington | Illinois | United States | 61704 |
| 166 | Illinois CancerCare-Canton | Canton | Illinois | United States | 61520 |
| 167 | Illinois CancerCare-Carthage | Carthage | Illinois | United States | 62321 |
| 168 | Northwestern University | Chicago | Illinois | United States | 60611 |
| 169 | John H Stroger Jr Hospital of Cook County | Chicago | Illinois | United States | 60612 |
| 170 | Rush University Medical Center | Chicago | Illinois | United States | 60612 |
| 171 | University of Illinois | Chicago | Illinois | United States | 60612 |
| 172 | Presence Resurrection Medical Center | Chicago | Illinois | United States | 60631 |
| 173 | University of Chicago Comprehensive Cancer Center | Chicago | Illinois | United States | 60637 |
| 174 | Advocate Illinois Masonic Medical Center | Chicago | Illinois | United States | 60657 |
| 175 | Carle on Vermilion | Danville | Illinois | United States | 61832 |
| 176 | Decatur Memorial Hospital | Decatur | Illinois | United States | 62526 |
| 177 | Carle Physician Group-Effingham | Effingham | Illinois | United States | 62401 |
| 178 | Elmhurst Memorial Hospital | Elmhurst | Illinois | United States | 60126 |
| 179 | Illinois CancerCare-Eureka | Eureka | Illinois | United States | 61530 |
| 180 | Illinois CancerCare-Galesburg | Galesburg | Illinois | United States | 61401 |
| 181 | Western Illinois Cancer Treatment Center | Galesburg | Illinois | United States | 61401 |
| 182 | Northwestern Medicine Cancer Center Delnor | Geneva | Illinois | United States | 60134 |
| 183 | Ingalls Memorial Hospital | Harvey | Illinois | United States | 60426 |
| 184 | Presence Saint Mary's Hospital | Kankakee | Illinois | United States | 60901 |
| 185 | Illinois CancerCare-Kewanee Clinic | Kewanee | Illinois | United States | 61443 |
| 186 | Illinois CancerCare-Macomb | Macomb | Illinois | United States | 61455 |
| 187 | Carle Physician Group-Mattoon/Charleston | Mattoon | Illinois | United States | 61938 |
| 188 | Loyola University Medical Center | Maywood | Illinois | United States | 60153 |
| 189 | Good Samaritan Regional Health Center | Mount Vernon | Illinois | United States | 62864 |
| 190 | Edward Hospital/Cancer Center | Naperville | Illinois | United States | 60540 |
| 191 | Carle Cancer Institute Normal | Normal | Illinois | United States | 61761 |
| 192 | Illinois CancerCare-Ottawa Clinic | Ottawa | Illinois | United States | 61350 |
| 193 | Radiation Oncology of Northern Illinois | Ottawa | Illinois | United States | 61350 |
| 194 | Illinois CancerCare-Pekin | Pekin | Illinois | United States | 61554 |
| 195 | OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center | Pekin | Illinois | United States | 61554 |
| 196 | Illinois CancerCare-Peoria | Peoria | Illinois | United States | 61615 |
| 197 | OSF Saint Francis Radiation Oncology at Peoria Cancer Center | Peoria | Illinois | United States | 61615 |
| 198 | Methodist Medical Center of Illinois | Peoria | Illinois | United States | 61636 |
| 199 | OSF Saint Francis Medical Center | Peoria | Illinois | United States | 61637 |
| 200 | Illinois CancerCare-Peru | Peru | Illinois | United States | 61354 |
| 201 | Valley Radiation Oncology | Peru | Illinois | United States | 61354 |
| 202 | Edward Hospital/Cancer Center?Plainfield | Plainfield | Illinois | United States | 60585 |
| 203 | Illinois CancerCare-Princeton | Princeton | Illinois | United States | 61356 |
| 204 | OSF Saint Anthony Medical Center | Rockford | Illinois | United States | 61108 |
| 205 | Saint John's Hospital | Springfield | Illinois | United States | 62702 |
| 206 | Memorial Medical Center | Springfield | Illinois | United States | 62781 |
| 207 | Carle Cancer Center | Urbana | Illinois | United States | 61801 |
| 208 | The Carle Foundation Hospital | Urbana | Illinois | United States | 61801 |
| 209 | Northwestern Medicine Cancer Center Warrenville | Warrenville | Illinois | United States | 60555 |
| 210 | Rush-Copley Healthcare Center | Yorkville | Illinois | United States | 60560 |
| 211 | Franciscan Saint Francis Health-Beech Grove | Beech Grove | Indiana | United States | 46107 |
| 212 | Elkhart Clinic | Elkhart | Indiana | United States | 46514-2098 |
| 213 | Michiana Hematology Oncology PC-Elkhart | Elkhart | Indiana | United States | 46514 |
| 214 | Elkhart General Hospital | Elkhart | Indiana | United States | 46515 |
| 215 | Radiation Oncology Associates PC | Fort Wayne | Indiana | United States | 46804 |
| 216 | Parkview Hospital Randallia | Fort Wayne | Indiana | United States | 46805 |
| 217 | Goshen Center for Cancer Care | Goshen | Indiana | United States | 46526 |
| 218 | Indiana University/Melvin and Bren Simon Cancer Center | Indianapolis | Indiana | United States | 46202 |
| 219 | IU Health Methodist Hospital | Indianapolis | Indiana | United States | 46202 |
| 220 | Community Howard Regional Health | Kokomo | Indiana | United States | 46904 |
| 221 | IU Health La Porte Hospital | La Porte | Indiana | United States | 46350 |
| 222 | Woodland Cancer Care Center | Michigan City | Indiana | United States | 46360 |
| 223 | Memorial Regional Cancer Center Day Road | Mishawaka | Indiana | United States | 46545 |
| 224 | Michiana Hematology Oncology PC-Mishawaka | Mishawaka | Indiana | United States | 46545 |
| 225 | Saint Joseph Regional Medical Center-Mishawaka | Mishawaka | Indiana | United States | 46545 |
| 226 | Michiana Hematology Oncology PC-Plymouth | Plymouth | Indiana | United States | 46563 |
| 227 | Reid Health | Richmond | Indiana | United States | 47374 |
| 228 | Memorial Hospital of South Bend | South Bend | Indiana | United States | 46601 |
| 229 | Michiana Hematology Oncology PC-South Bend | South Bend | Indiana | United States | 46601 |
| 230 | Northern Indiana Cancer Research Consortium | South Bend | Indiana | United States | 46628 |
| 231 | Michiana Hematology Oncology PC-Westville | Westville | Indiana | United States | 46391 |
| 232 | Mary Greeley Medical Center | Ames | Iowa | United States | 50010 |
| 233 | McFarland Clinic PC - Ames | Ames | Iowa | United States | 50010 |
| 234 | McFarland Clinic PC-Boone | Boone | Iowa | United States | 50036 |
| 235 | Medical Oncology and Hematology Associates-West Des Moines | Clive | Iowa | United States | 50325 |
| 236 | Mercy Cancer Center-West Lakes | Clive | Iowa | United States | 50325 |
| 237 | Iowa Methodist Medical Center | Des Moines | Iowa | United States | 50309 |
| 238 | Iowa-Wide Oncology Research Coalition NCORP | Des Moines | Iowa | United States | 50309 |
| 239 | Medical Oncology and Hematology Associates-Des Moines | Des Moines | Iowa | United States | 50309 |
| 240 | Medical Oncology and Hematology Associates-Laurel | Des Moines | Iowa | United States | 50314 |
| 241 | Mercy Medical Center - Des Moines | Des Moines | Iowa | United States | 50314 |
| 242 | Iowa Lutheran Hospital | Des Moines | Iowa | United States | 50316 |
| 243 | McFarland Clinic PC-Jefferson | Jefferson | Iowa | United States | 50129 |
| 244 | McFarland Clinic PC-Marshalltown | Marshalltown | Iowa | United States | 50158 |
| 245 | Siouxland Regional Cancer Center | Sioux City | Iowa | United States | 51101 |
| 246 | Mercy Medical Center-Sioux City | Sioux City | Iowa | United States | 51102 |
| 247 | Saint Luke's Regional Medical Center | Sioux City | Iowa | United States | 51104 |
| 248 | Methodist West Hospital | West Des Moines | Iowa | United States | 50266-7700 |
| 249 | Mercy Medical Center-West Lakes | West Des Moines | Iowa | United States | 50266 |
| 250 | Cancer Center of Kansas - Chanute | Chanute | Kansas | United States | 66720 |
| 251 | Cancer Center of Kansas - Dodge City | Dodge City | Kansas | United States | 67801 |
| 252 | Cancer Center of Kansas - El Dorado | El Dorado | Kansas | United States | 67042 |
| 253 | Cancer Center of Kansas - Fort Scott | Fort Scott | Kansas | United States | 66701 |
| 254 | Cancer Center of Kansas-Independence | Independence | Kansas | United States | 67301 |
| 255 | Cancer Center of Kansas-Kingman | Kingman | Kansas | United States | 67068 |
| 256 | Lawrence Memorial Hospital | Lawrence | Kansas | United States | 66044 |
| 257 | Cancer Center of Kansas-Liberal | Liberal | Kansas | United States | 67905 |
| 258 | Cancer Center of Kansas-Manhattan | Manhattan | Kansas | United States | 66502 |
| 259 | Cancer Center of Kansas - McPherson | McPherson | Kansas | United States | 67460 |
| 260 | Cancer Center of Kansas - Newton | Newton | Kansas | United States | 67114 |
| 261 | Menorah Medical Center | Overland Park | Kansas | United States | 66209 |
| 262 | Saint Luke's South Hospital | Overland Park | Kansas | United States | 66213 |
| 263 | Cancer Center of Kansas - Parsons | Parsons | Kansas | United States | 67357 |
| 264 | Kansas City NCI Community Oncology Research Program | Prairie Village | Kansas | United States | 66208 |
| 265 | Cancer Center of Kansas - Pratt | Pratt | Kansas | United States | 67124 |
| 266 | Cancer Center of Kansas - Salina | Salina | Kansas | United States | 67401 |
| 267 | Cotton O'Neil Cancer Center / Stormont Vail Health | Topeka | Kansas | United States | 66606 |
| 268 | Cancer Center of Kansas - Wellington | Wellington | Kansas | United States | 67152 |
| 269 | Associates In Womens Health | Wichita | Kansas | United States | 67208 |
| 270 | Cancer Center of Kansas-Wichita Medical Arts Tower | Wichita | Kansas | United States | 67208 |
| 271 | Ascension Via Christi Hospitals Wichita | Wichita | Kansas | United States | 67214 |
| 272 | Cancer Center of Kansas - Wichita | Wichita | Kansas | United States | 67214 |
| 273 | Wesley Medical Center | Wichita | Kansas | United States | 67214 |
| 274 | Wichita NCI Community Oncology Research Program | Wichita | Kansas | United States | 67214 |
| 275 | Cancer Center of Kansas - Winfield | Winfield | Kansas | United States | 67156 |
| 276 | Baptist Health Lexington | Lexington | Kentucky | United States | 40503 |
| 277 | University of Kentucky/Markey Cancer Center | Lexington | Kentucky | United States | 40536 |
| 278 | Tulane University Health Sciences Center | New Orleans | Louisiana | United States | 70112 |
| 279 | Ochsner Medical Center Jefferson | New Orleans | Louisiana | United States | 70121 |
| 280 | LSU Health Sciences Center at Shreveport | Shreveport | Louisiana | United States | 71103 |
| 281 | University of Maryland/Greenebaum Cancer Center | Baltimore | Maryland | United States | 21201 |
| 282 | Sinai Hospital of Baltimore | Baltimore | Maryland | United States | 21215 |
| 283 | Saint Agnes Hospital | Baltimore | Maryland | United States | 21229 |
| 284 | UM Baltimore Washington Medical Center/Tate Cancer Center | Glen Burnie | Maryland | United States | 21061 |
| 285 | TidalHealth Peninsula Regional | Salisbury | Maryland | United States | 21801 |
| 286 | Massachusetts General Hospital Cancer Center | Boston | Massachusetts | United States | 02114 |
| 287 | Brigham and Women's Hospital | Boston | Massachusetts | United States | 02115 |
| 288 | Boston Medical Center | Boston | Massachusetts | United States | 02118 |
| 289 | Lahey Hospital and Medical Center | Burlington | Massachusetts | United States | 01805 |
| 290 | Saint Anne's Hospital | Fall River | Massachusetts | United States | 02721 |
| 291 | Berkshire Medical Center - Cancer Center | Pittsfield | Massachusetts | United States | 01201 |
| 292 | Baystate Medical Center | Springfield | Massachusetts | United States | 01199 |
| 293 | Bixby Medical Center | Adrian | Michigan | United States | 49221 |
| 294 | Hickman Cancer Center | Adrian | Michigan | United States | 49221 |
| 295 | Saint Joseph Mercy Hospital | Ann Arbor | Michigan | United States | 48106 |
| 296 | University of Michigan Comprehensive Cancer Center | Ann Arbor | Michigan | United States | 48109 |
| 297 | Henry Ford Cancer Institute-Downriver | Brownstown | Michigan | United States | 48183 |
| 298 | Henry Ford Macomb Hospital-Clinton Township | Clinton Township | Michigan | United States | 48038 |
| 299 | Huron Valley-Sinai Hospital | Commerce | Michigan | United States | 48382 |
| 300 | Wayne State University/Karmanos Cancer Institute | Detroit | Michigan | United States | 48201 |
| 301 | Henry Ford Hospital | Detroit | Michigan | United States | 48202 |
| 302 | Ascension Saint John Hospital | Detroit | Michigan | United States | 48236 |
| 303 | Green Bay Oncology - Escanaba | Escanaba | Michigan | United States | 49829 |
| 304 | Weisberg Cancer Treatment Center | Farmington Hills | Michigan | United States | 48334 |
| 305 | Mercy Health Saint Mary's | Grand Rapids | Michigan | United States | 49503 |
| 306 | Spectrum Health at Butterworth Campus | Grand Rapids | Michigan | United States | 49503 |
| 307 | Green Bay Oncology - Iron Mountain | Iron Mountain | Michigan | United States | 49801 |
| 308 | Bronson Methodist Hospital | Kalamazoo | Michigan | United States | 49007 |
| 309 | West Michigan Cancer Center | Kalamazoo | Michigan | United States | 49007 |
| 310 | Borgess Medical Center | Kalamazoo | Michigan | United States | 49048 |
| 311 | Trinity Health Saint Mary Mercy Livonia Hospital | Livonia | Michigan | United States | 48154 |
| 312 | Mercy Memorial Hospital | Monroe | Michigan | United States | 48162 |
| 313 | Toledo Clinic Cancer Centers-Monroe | Monroe | Michigan | United States | 48162 |
| 314 | Mercy Health Mercy Campus | Muskegon | Michigan | United States | 49444 |
| 315 | Saint Joseph Mercy Oakland | Pontiac | Michigan | United States | 48341 |
| 316 | William Beaumont Hospital-Royal Oak | Royal Oak | Michigan | United States | 48073 |
| 317 | Lakeland Medical Center Saint Joseph | Saint Joseph | Michigan | United States | 49085 |
| 318 | Marie Yeager Cancer Center | Saint Joseph | Michigan | United States | 49085 |
| 319 | William Beaumont Hospital - Troy | Troy | Michigan | United States | 48085 |
| 320 | Saint John Macomb-Oakland Hospital | Warren | Michigan | United States | 48093 |
| 321 | Henry Ford West Bloomfield Hospital | West Bloomfield | Michigan | United States | 48322 |
| 322 | Metro Health Hospital | Wyoming | Michigan | United States | 49519 |
| 323 | Fairview Ridges Hospital | Burnsville | Minnesota | United States | 55337 |
| 324 | Mercy Hospital | Coon Rapids | Minnesota | United States | 55433 |
| 325 | Fairview Southdale Hospital | Edina | Minnesota | United States | 55435 |
| 326 | Unity Hospital | Fridley | Minnesota | United States | 55432 |
| 327 | Minnesota Oncology Hematology PA-Maplewood | Maplewood | Minnesota | United States | 55109 |
| 328 | Saint John's Hospital - Healtheast | Maplewood | Minnesota | United States | 55109 |
| 329 | Abbott-Northwestern Hospital | Minneapolis | Minnesota | United States | 55407 |
| 330 | Hennepin County Medical Center | Minneapolis | Minnesota | United States | 55415 |
| 331 | North Memorial Medical Health Center | Robbinsdale | Minnesota | United States | 55422 |
| 332 | Mayo Clinic in Rochester | Rochester | Minnesota | United States | 55905 |
| 333 | Metro Minnesota Community Oncology Research Consortium | Saint Louis Park | Minnesota | United States | 55416 |
| 334 | Park Nicollet Clinic - Saint Louis Park | Saint Louis Park | Minnesota | United States | 55416 |
| 335 | Regions Hospital | Saint Paul | Minnesota | United States | 55101 |
| 336 | United Hospital | Saint Paul | Minnesota | United States | 55102 |
| 337 | Ridgeview Medical Center | Waconia | Minnesota | United States | 55387 |
| 338 | Rice Memorial Hospital | Willmar | Minnesota | United States | 56201 |
| 339 | University of Mississippi Medical Center | Jackson | Mississippi | United States | 39216 |
| 340 | Singing River Hospital | Pascagoula | Mississippi | United States | 39581 |
| 341 | Central Care Cancer Center - Bolivar | Bolivar | Missouri | United States | 65613 |
| 342 | Parkland Health Center-Bonne Terre | Bonne Terre | Missouri | United States | 63628 |
| 343 | Cox Cancer Center Branson | Branson | Missouri | United States | 65616 |
| 344 | Saint Francis Medical Center | Cape Girardeau | Missouri | United States | 63703 |
| 345 | Southeast Cancer Center | Cape Girardeau | Missouri | United States | 63703 |
| 346 | University of Missouri - Ellis Fischel | Columbia | Missouri | United States | 65212 |
| 347 | Siteman Cancer Center at West County Hospital | Creve Coeur | Missouri | United States | 63141 |
| 348 | Centerpoint Medical Center LLC | Independence | Missouri | United States | 64057 |
| 349 | Capital Region Southwest Campus | Jefferson City | Missouri | United States | 65109 |
| 350 | Freeman Health System | Joplin | Missouri | United States | 64804 |
| 351 | Mercy Hospital Joplin | Joplin | Missouri | United States | 64804 |
| 352 | Saint Luke's Hospital of Kansas City | Kansas City | Missouri | United States | 64111 |
| 353 | Heartland Hematology and Oncology Associates Incorporated | Kansas City | Missouri | United States | 64118 |
| 354 | Research Medical Center | Kansas City | Missouri | United States | 64132 |
| 355 | Saint Luke's East - Lee's Summit | Lee's Summit | Missouri | United States | 64086 |
| 356 | Liberty Radiation Oncology Center | Liberty | Missouri | United States | 64068 |
| 357 | Delbert Day Cancer Institute at PCRMC | Rolla | Missouri | United States | 65401 |
| 358 | Mercy Clinic-Rolla-Cancer and Hematology | Rolla | Missouri | United States | 65401 |
| 359 | Heartland Regional Medical Center | Saint Joseph | Missouri | United States | 64506 |
| 360 | SSM Health Saint Louis University Hospital | Saint Louis | Missouri | United States | 63104 |
| 361 | Saint Louis Cancer and Breast Institute-South City | Saint Louis | Missouri | United States | 63109 |
| 362 | Washington University School of Medicine | Saint Louis | Missouri | United States | 63110 |
| 363 | Siteman Cancer Center-South County | Saint Louis | Missouri | United States | 63129 |
| 364 | Missouri Baptist Medical Center | Saint Louis | Missouri | United States | 63131 |
| 365 | Center for Cancer Care and Research | Saint Louis | Missouri | United States | 63141 |
| 366 | Mercy Hospital Saint Louis | Saint Louis | Missouri | United States | 63141 |
| 367 | Saint Louis-Cape Girardeau CCOP | Saint Louis | Missouri | United States | 63141 |
| 368 | Siteman Cancer Center at Saint Peters Hospital | Saint Peters | Missouri | United States | 63376 |
| 369 | Sainte Genevieve County Memorial Hospital | Sainte Genevieve | Missouri | United States | 63670 |
| 370 | Cancer Research for the Ozarks NCORP | Springfield | Missouri | United States | 65804 |
| 371 | Mercy Hospital Springfield | Springfield | Missouri | United States | 65804 |
| 372 | CoxHealth South Hospital | Springfield | Missouri | United States | 65807 |
| 373 | Missouri Baptist Sullivan Hospital | Sullivan | Missouri | United States | 63080 |
| 374 | Missouri Baptist Outpatient Center-Sunset Hills | Sunset Hills | Missouri | United States | 63127 |
| 375 | Billings Clinic Cancer Center | Billings | Montana | United States | 59101 |
| 376 | Northern Rockies Radiation Oncology Center | Billings | Montana | United States | 59101 |
| 377 | Saint Vincent Healthcare | Billings | Montana | United States | 59101 |
| 378 | Montana Cancer Consortium NCORP | Billings | Montana | United States | 59102 |
| 379 | Bozeman Deaconess Hospital | Bozeman | Montana | United States | 59715 |
| 380 | Saint James Community Hospital and Cancer Treatment Center | Butte | Montana | United States | 59701 |
| 381 | Benefis Healthcare- Sletten Cancer Institute | Great Falls | Montana | United States | 59405 |
| 382 | Berdeaux, Donald MD (UIA Investigator) | Great Falls | Montana | United States | 59405 |
| 383 | Great Falls Clinic | Great Falls | Montana | United States | 59405 |
| 384 | Saint Peter's Community Hospital | Helena | Montana | United States | 59601 |
| 385 | Kalispell Regional Medical Center | Kalispell | Montana | United States | 59901 |
| 386 | Montana Cancer Specialists | Missoula | Montana | United States | 59802 |
| 387 | Saint Patrick Hospital - Community Hospital | Missoula | Montana | United States | 59802 |
| 388 | CHI Health Saint Francis | Grand Island | Nebraska | United States | 68803 |
| 389 | CHI Health Good Samaritan | Kearney | Nebraska | United States | 68847 |
| 390 | Nebraska Cancer Research Center | Lincoln | Nebraska | United States | 68510 |
| 391 | Missouri Valley Cancer Consortium | Omaha | Nebraska | United States | 68106 |
| 392 | Nebraska Methodist Hospital | Omaha | Nebraska | United States | 68114 |
| 393 | Alegent Health Immanuel Medical Center | Omaha | Nebraska | United States | 68122 |
| 394 | Alegent Health Bergan Mercy Medical Center | Omaha | Nebraska | United States | 68124 |
| 395 | Alegent Health Lakeside Hospital | Omaha | Nebraska | United States | 68130 |
| 396 | Creighton University Medical Center | Omaha | Nebraska | United States | 68131 |
| 397 | University of Nebraska Medical Center | Omaha | Nebraska | United States | 68198 |
| 398 | Cancer and Blood Specialists-Henderson | Henderson | Nevada | United States | 89052 |
| 399 | Comprehensive Cancer Centers of Nevada - Henderson | Henderson | Nevada | United States | 89052 |
| 400 | Las Vegas Cancer Center-Henderson | Henderson | Nevada | United States | 89052 |
| 401 | Comprehensive Cancer Centers of Nevada-Southeast Henderson | Henderson | Nevada | United States | 89074 |
| 402 | GenesisCare USA - Henderson | Henderson | Nevada | United States | 89074 |
| 403 | University Medical Center of Southern Nevada | Las Vegas | Nevada | United States | 89102 |
| 404 | Cancer and Blood Specialists-Shadow | Las Vegas | Nevada | United States | 89106 |
| 405 | Radiation Oncology Centers of Nevada Central | Las Vegas | Nevada | United States | 89106 |
| 406 | GenesisCare USA - Las Vegas | Las Vegas | Nevada | United States | 89109 |
| 407 | HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway | Las Vegas | Nevada | United States | 89109 |
| 408 | HealthCare Partners Medical Group Oncology/Hematology-San Martin | Las Vegas | Nevada | United States | 89113 |
| 409 | Radiation Oncology Centers of Nevada Southeast | Las Vegas | Nevada | United States | 89119 |
| 410 | Cancer Therapy and Integrative Medicine | Las Vegas | Nevada | United States | 89121 |
| 411 | Cancer and Blood Specialists-Tenaya | Las Vegas | Nevada | United States | 89128 |
| 412 | Comprehensive Cancer Centers of Nevada - Northwest | Las Vegas | Nevada | United States | 89128 |
| 413 | GenesisCare USA - Vegas Tenaya | Las Vegas | Nevada | United States | 89128 |
| 414 | HealthCare Partners Medical Group Oncology/Hematology-Tenaya | Las Vegas | Nevada | United States | 89128 |
| 415 | Comprehensive Cancer Centers of Nevada-Summerlin | Las Vegas | Nevada | United States | 89144 |
| 416 | Summerlin Hospital Medical Center | Las Vegas | Nevada | United States | 89144 |
| 417 | Las Vegas Cancer Center-Medical Center | Las Vegas | Nevada | United States | 89148-2405 |
| 418 | Comprehensive Cancer Centers of Nevada | Las Vegas | Nevada | United States | 89148 |
| 419 | GenesisCare USA - Fort Apache | Las Vegas | Nevada | United States | 89148 |
| 420 | OptumCare Cancer Care at Fort Apache | Las Vegas | Nevada | United States | 89148 |
| 421 | HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills | Las Vegas | Nevada | United States | 89149 |
| 422 | Comprehensive Cancer Centers of Nevada - Central Valley | Las Vegas | Nevada | United States | 89169 |
| 423 | Nevada Cancer Research Foundation NCORP | Las Vegas | Nevada | United States | 89169 |
| 424 | Renown Regional Medical Center | Reno | Nevada | United States | 89502 |
| 425 | Elliot Hospital | Manchester | New Hampshire | United States | 03103 |
| 426 | Memorial Sloan Kettering Basking Ridge | Basking Ridge | New Jersey | United States | 07920 |
| 427 | Cooper Hospital University Medical Center | Camden | New Jersey | United States | 08103 |
| 428 | Saint Barnabas Medical Center | Livingston | New Jersey | United States | 07039 |
| 429 | Memorial Sloan Kettering Monmouth | Middletown | New Jersey | United States | 07748 |
| 430 | Virtua Memorial | Mount Holly | New Jersey | United States | 08060 |
| 431 | Rutgers New Jersey Medical School | Newark | New Jersey | United States | 07101 |
| 432 | Newark Beth Israel Medical Center | Newark | New Jersey | United States | 07112 |
| 433 | The Valley Hospital-Luckow Pavilion | Paramus | New Jersey | United States | 07652 |
| 434 | Valley Hospital | Ridgewood | New Jersey | United States | 07450 |
| 435 | Sparta Cancer Treatment Center | Sparta | New Jersey | United States | 07871 |
| 436 | MD Anderson Cancer Center at Cooper-Voorhees | Voorhees | New Jersey | United States | 08043 |
| 437 | Virtua Voorhees | Voorhees | New Jersey | United States | 08043 |
| 438 | Valley Health System-Hematology/Oncology | Westwood | New Jersey | United States | 07675 |
| 439 | New York Oncology Hematology PC - Albany | Albany | New York | United States | 12206 |
| 440 | Maimonides Medical Center | Brooklyn | New York | United States | 11219 |
| 441 | Sands Cancer Center | Canandaigua | New York | United States | 14424 |
| 442 | Memorial Sloan Kettering Commack | Commack | New York | United States | 11725 |
| 443 | Glens Falls Hospital | Glens Falls | New York | United States | 12801 |
| 444 | Memorial Sloan Kettering Westchester | Harrison | New York | United States | 10604 |
| 445 | Garnet Health Medical Center | Middletown | New York | United States | 10940 |
| 446 | NYU Winthrop Hospital | Mineola | New York | United States | 11501 |
| 447 | Long Island Jewish Medical Center | New Hyde Park | New York | United States | 11040 |
| 448 | Laura and Isaac Perlmutter Cancer Center at NYU Langone | New York | New York | United States | 10016 |
| 449 | Memorial Sloan Kettering Cancer Center | New York | New York | United States | 10065 |
| 450 | Wilmot Cancer Institute Radiation Oncology at Greece | Rochester | New York | United States | 14606 |
| 451 | Highland Hospital | Rochester | New York | United States | 14620 |
| 452 | University of Rochester | Rochester | New York | United States | 14642 |
| 453 | Memorial Sloan Kettering Sleepy Hollow | Sleepy Hollow | New York | United States | 10591 |
| 454 | Stony Brook University Medical Center | Stony Brook | New York | United States | 11794 |
| 455 | Memorial Sloan Kettering Nassau | Uniondale | New York | United States | 11553 |
| 456 | Carolinas Medical Center/Levine Cancer Institute | Charlotte | North Carolina | United States | 28203 |
| 457 | Novant Health Presbyterian Medical Center | Charlotte | North Carolina | United States | 28204 |
| 458 | Atrium Health Pineville/LCI-Pineville | Charlotte | North Carolina | United States | 28210 |
| 459 | Atrium Health Cabarrus/LCI-Concord | Concord | North Carolina | United States | 28025 |
| 460 | East Carolina University | Greenville | North Carolina | United States | 27834 |
| 461 | AdventHealth Hendersonville | Hendersonville | North Carolina | United States | 28792 |
| 462 | Vidant Oncology-Kinston | Kinston | North Carolina | United States | 28501 |
| 463 | Matthews Radiation Oncology Center | Matthews | North Carolina | United States | 28105 |
| 464 | UNC Rex Cancer Center | Raleigh | North Carolina | United States | 27607 |
| 465 | Rutherford Hospital | Rutherfordton | North Carolina | United States | 28139 |
| 466 | Southeast Clinical Oncology Research Consortium NCORP | Winston-Salem | North Carolina | United States | 27104 |
| 467 | Summa Health System - Akron Campus | Akron | Ohio | United States | 44304 |
| 468 | Cleveland Clinic Akron General | Akron | Ohio | United States | 44307 |
| 469 | Radiation Oncology Center | Alliance | Ohio | United States | 44601 |
| 470 | Summa Health System - Barberton Campus | Barberton | Ohio | United States | 44203 |
| 471 | Strecker Cancer Center-Belpre | Belpre | Ohio | United States | 45714 |
| 472 | Toledo Clinic Cancer Centers-Bowling Green | Bowling Green | Ohio | United States | 43402 |
| 473 | Adena Regional Medical Center | Chillicothe | Ohio | United States | 45601 |
| 474 | University of Cincinnati Cancer Center-UC Medical Center | Cincinnati | Ohio | United States | 45219 |
| 475 | Good Samaritan Hospital - Cincinnati | Cincinnati | Ohio | United States | 45220 |
| 476 | Bethesda North Hospital | Cincinnati | Ohio | United States | 45242 |
| 477 | MetroHealth Medical Center | Cleveland | Ohio | United States | 44109 |
| 478 | Cleveland Clinic Cancer Center/Fairview Hospital | Cleveland | Ohio | United States | 44111 |
| 479 | Cleveland Clinic Foundation | Cleveland | Ohio | United States | 44195 |
| 480 | Ohio State University Comprehensive Cancer Center | Columbus | Ohio | United States | 43210 |
| 481 | Columbus Oncology and Hematology Associates Inc | Columbus | Ohio | United States | 43214 |
| 482 | Riverside Methodist Hospital | Columbus | Ohio | United States | 43214 |
| 483 | Columbus NCI Community Oncology Research Program | Columbus | Ohio | United States | 43215 |
| 484 | Grant Medical Center | Columbus | Ohio | United States | 43215 |
| 485 | The Mark H Zangmeister Center | Columbus | Ohio | United States | 43219 |
| 486 | Mount Carmel Health Center West | Columbus | Ohio | United States | 43222 |
| 487 | Doctors Hospital | Columbus | Ohio | United States | 43228 |
| 488 | Grandview Hospital | Dayton | Ohio | United States | 45405 |
| 489 | Good Samaritan Hospital - Dayton | Dayton | Ohio | United States | 45406 |
| 490 | Miami Valley Hospital | Dayton | Ohio | United States | 45409 |
| 491 | Miami Valley Hospital North | Dayton | Ohio | United States | 45415 |
| 492 | Delaware Health Center-Grady Cancer Center | Delaware | Ohio | United States | 43015 |
| 493 | Delaware Radiation Oncology | Delaware | Ohio | United States | 43015 |
| 494 | Grady Memorial Hospital | Delaware | Ohio | United States | 43015 |
| 495 | Mercy Cancer Center-Elyria | Elyria | Ohio | United States | 44035 |
| 496 | Blanchard Valley Hospital | Findlay | Ohio | United States | 45840 |
| 497 | Atrium Medical Center-Middletown Regional Hospital | Franklin | Ohio | United States | 45005-1066 |
| 498 | Cleveland Clinic Cancer Center Independence | Independence | Ohio | United States | 44131 |
| 499 | Kettering Medical Center | Kettering | Ohio | United States | 45429 |
| 500 | Fairfield Medical Center | Lancaster | Ohio | United States | 43130 |
| 501 | Lancaster Radiation Oncology | Lancaster | Ohio | United States | 43130 |
| 502 | Lima Memorial Hospital | Lima | Ohio | United States | 45804 |
| 503 | Marietta Memorial Hospital | Marietta | Ohio | United States | 45750 |
| 504 | Toledo Clinic Cancer Centers-Maumee | Maumee | Ohio | United States | 43537 |
| 505 | Toledo Radiation Oncology at Northwest Ohio Onocolgy Center | Maumee | Ohio | United States | 43537 |
| 506 | Hillcrest Hospital Cancer Center | Mayfield Heights | Ohio | United States | 44124 |
| 507 | Summa Health Medina Medical Center | Medina | Ohio | United States | 44256 |
| 508 | Knox Community Hospital | Mount Vernon | Ohio | United States | 43050 |
| 509 | Licking Memorial Hospital | Newark | Ohio | United States | 43055 |
| 510 | Newark Radiation Oncology | Newark | Ohio | United States | 43055 |
| 511 | Saint Charles Hospital | Oregon | Ohio | United States | 43616 |
| 512 | Toledo Clinic Cancer Centers-Oregon | Oregon | Ohio | United States | 43616 |
| 513 | Southern Ohio Medical Center | Portsmouth | Ohio | United States | 45662 |
| 514 | University Hospitals Portage Medical Center | Ravenna | Ohio | United States | 44266 |
| 515 | UH Seidman Cancer Center at Salem Regional Medical Center | Salem | Ohio | United States | 44460 |
| 516 | North Coast Cancer Care | Sandusky | Ohio | United States | 44870 |
| 517 | Springfield Regional Medical Center | Springfield | Ohio | United States | 45505 |
| 518 | Cleveland Clinic Cancer Center Strongsville | Strongsville | Ohio | United States | 44136 |
| 519 | ProMedica Flower Hospital | Sylvania | Ohio | United States | 43560 |
| 520 | Mercy Hospital of Tiffin | Tiffin | Ohio | United States | 44883 |
| 521 | Saint Vincent Mercy Medical Center | Toledo | Ohio | United States | 43608 |
| 522 | University of Toledo | Toledo | Ohio | United States | 43614 |
| 523 | Toledo Community Hospital Oncology Program CCOP | Toledo | Ohio | United States | 43617 |
| 524 | Mercy Health - Saint Anne Hospital | Toledo | Ohio | United States | 43623 |
| 525 | Toledo Clinic Cancer Centers-Toledo | Toledo | Ohio | United States | 43623 |
| 526 | Upper Valley Medical Center | Troy | Ohio | United States | 45373 |
| 527 | Fulton County Health Center | Wauseon | Ohio | United States | 43567 |
| 528 | University of Cincinnati Cancer Center-West Chester | West Chester | Ohio | United States | 45069 |
| 529 | Saint Ann's Hospital | Westerville | Ohio | United States | 43081 |
| 530 | Cancer Treatment Center | Wooster | Ohio | United States | 44691 |
| 531 | Cleveland Clinic Wooster Family Health and Surgery Center | Wooster | Ohio | United States | 44691 |
| 532 | Greene Memorial Hospital | Xenia | Ohio | United States | 45385 |
| 533 | Genesis Healthcare System Cancer Care Center | Zanesville | Ohio | United States | 43701 |
| 534 | University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | United States | 73104 |
| 535 | Natalie Warren Bryant Cancer Center at Saint Francis | Tulsa | Oklahoma | United States | 74136 |
| 536 | Saint Charles Health System | Bend | Oregon | United States | 97701 |
| 537 | Clackamas Radiation Oncology Center | Clackamas | Oregon | United States | 97015 |
| 538 | Legacy Mount Hood Medical Center | Gresham | Oregon | United States | 97030 |
| 539 | Providence Milwaukie Hospital | Milwaukie | Oregon | United States | 97222 |
| 540 | Providence Newberg Medical Center | Newberg | Oregon | United States | 97132 |
| 541 | Providence Willamette Falls Medical Center | Oregon City | Oregon | United States | 97045 |
| 542 | Legacy Good Samaritan Hospital and Medical Center | Portland | Oregon | United States | 97210 |
| 543 | Providence Portland Medical Center | Portland | Oregon | United States | 97213 |
| 544 | Providence Saint Vincent Medical Center | Portland | Oregon | United States | 97225 |
| 545 | Oregon Health and Science University | Portland | Oregon | United States | 97239 |
| 546 | Mid-Columbia Medical Center/Celilo Cancer Center | The Dalles | Oregon | United States | 97058 |
| 547 | Jefferson Abington Hospital | Abington | Pennsylvania | United States | 19001 |
| 548 | Lehigh Valley Hospital-Cedar Crest | Allentown | Pennsylvania | United States | 18103 |
| 549 | Bryn Mawr Hospital | Bryn Mawr | Pennsylvania | United States | 19010 |
| 550 | Geisinger Medical Center | Danville | Pennsylvania | United States | 17822 |
| 551 | Mercy Fitzgerald Hospital | Darby | Pennsylvania | United States | 19023-1291 |
| 552 | Delaware County Memorial Hospital | Drexel Hill | Pennsylvania | United States | 19026 |
| 553 | Northeast Radiation Oncology Center | Dunmore | Pennsylvania | United States | 18512 |
| 554 | Easton Hospital | Easton | Pennsylvania | United States | 18042 |
| 555 | Adams Cancer Center | Gettysburg | Pennsylvania | United States | 17325 |
| 556 | Cherry Tree Cancer Center | Hanover | Pennsylvania | United States | 17331 |
| 557 | Riddle Memorial Hospital | Media | Pennsylvania | United States | 19063 |
| 558 | Allegheny Valley Hospital | Natrona Heights | Pennsylvania | United States | 15065 |
| 559 | Paoli Memorial Hospital | Paoli | Pennsylvania | United States | 19301 |
| 560 | Pennsylvania Hospital | Philadelphia | Pennsylvania | United States | 19107 |
| 561 | Thomas Jefferson University Hospital | Philadelphia | Pennsylvania | United States | 19107 |
| 562 | Jefferson Torresdale Hospital | Philadelphia | Pennsylvania | United States | 19114 |
| 563 | Einstein Medical Center Philadelphia | Philadelphia | Pennsylvania | United States | 19141 |
| 564 | Guthrie Medical Group PC-Robert Packer Hospital | Sayre | Pennsylvania | United States | 18840 |
| 565 | Crozer-Chester Medical Center | Upland | Pennsylvania | United States | 19013 |
| 566 | Reading Hospital | West Reading | Pennsylvania | United States | 19611 |
| 567 | Geisinger Wyoming Valley/Henry Cancer Center | Wilkes-Barre | Pennsylvania | United States | 18711 |
| 568 | Lankenau Medical Center | Wynnewood | Pennsylvania | United States | 19096 |
| 569 | Main Line Health NCORP | Wynnewood | Pennsylvania | United States | 19096 |
| 570 | WellSpan Health-York Hospital | York | Pennsylvania | United States | 17403 |
| 571 | Rhode Island Hospital | Providence | Rhode Island | United States | 02903 |
| 572 | Radiation Oncology Associates Incorporated | Providence | Rhode Island | United States | 02904 |
| 573 | Miriam Hospital | Providence | Rhode Island | United States | 02906 |
| 574 | AnMed Health Cancer Center | Anderson | South Carolina | United States | 29621 |
| 575 | Prisma Health Cancer Institute - Spartanburg | Boiling Springs | South Carolina | United States | 29316 |
| 576 | Medical University of South Carolina | Charleston | South Carolina | United States | 29425 |
| 577 | Prisma Health Cancer Institute - Easley | Easley | South Carolina | United States | 29640 |
| 578 | Greenville Health System Cancer Institute-Andrews | Greenville | South Carolina | United States | 29601 |
| 579 | Saint Francis Hospital | Greenville | South Carolina | United States | 29601 |
| 580 | Prisma Health Cancer Institute - Butternut | Greenville | South Carolina | United States | 29605 |
| 581 | Prisma Health Cancer Institute - Faris | Greenville | South Carolina | United States | 29605 |
| 582 | Prisma Health Greenville Memorial Hospital | Greenville | South Carolina | United States | 29605 |
| 583 | Prisma Health Cancer Institute - Eastside | Greenville | South Carolina | United States | 29615 |
| 584 | Prisma Health Cancer Institute - Greer | Greer | South Carolina | United States | 29650 |
| 585 | Gibbs Cancer Center-Pelham | Greer | South Carolina | United States | 29651 |
| 586 | Carolina Blood and Cancer Care Associates PA-Lancaster | Lancaster | South Carolina | United States | 29720 |
| 587 | Carolina Blood and Cancer Care Associates PA | Rock Hill | South Carolina | United States | 29732 |
| 588 | Prisma Health Cancer Institute - Seneca | Seneca | South Carolina | United States | 29672 |
| 589 | Spartanburg Medical Center | Spartanburg | South Carolina | United States | 29303 |
| 590 | Rapid City Regional Hospital | Rapid City | South Dakota | United States | 57701 |
| 591 | Avera Cancer Institute | Sioux Falls | South Dakota | United States | 57105 |
| 592 | Vanderbilt University/Ingram Cancer Center | Nashville | Tennessee | United States | 37232 |
| 593 | The Don and Sybil Harrington Cancer Center | Amarillo | Texas | United States | 79106 |
| 594 | Texas Oncology-Arlington South | Arlington | Texas | United States | 76014 |
| 595 | Texas Oncology-Austin Midtown | Austin | Texas | United States | 78705 |
| 596 | Texas Oncology - Central Austin Cancer Center | Austin | Texas | United States | 78731 |
| 597 | Texas Oncology - South Austin Cancer Center | Austin | Texas | United States | 78745 |
| 598 | Texas Oncology Bedford | Bedford | Texas | United States | 76022 |
| 599 | Texas Oncology - Denison Cancer Center | Denison | Texas | United States | 75020 |
| 600 | Texas Oncology-Flower Mound | Flower Mound | Texas | United States | 75028 |
| 601 | Texas Oncology - Fort Worth Cancer Center | Fort Worth | Texas | United States | 76104 |
| 602 | University of Texas Medical Branch | Galveston | Texas | United States | 77555-0565 |
| 603 | Memorial Hermann Memorial City Medical Center | Houston | Texas | United States | 77024 |
| 604 | M D Anderson Cancer Center | Houston | Texas | United States | 77030 |
| 605 | UTMB Cancer Center at Victory Lakes | League City | Texas | United States | 77573 |
| 606 | Texas Oncology - Lewisville | Lewisville | Texas | United States | 75067 |
| 607 | Texas Oncology-Longview Cancer Center | Longview | Texas | United States | 75601 |
| 608 | Texas Oncology-McKinney | McKinney | Texas | United States | 75071 |
| 609 | Texas Oncology-Seton Williamson | Round Rock | Texas | United States | 78665 |
| 610 | Texas Oncology - Round Rock Cancer Center | Round Rock | Texas | United States | 78681 |
| 611 | Cancer Care Centers of South Texas- Northeast | San Antonio | Texas | United States | 78217 |
| 612 | Texas Oncology Cancer Center Sugar Land | Sugar Land | Texas | United States | 77479 |
| 613 | Scott and White Memorial Hospital | Temple | Texas | United States | 76508 |
| 614 | Tyler Cancer Center | Tyler | Texas | United States | 75702 |
| 615 | Deke Slayton Cancer Center | Webster | Texas | United States | 77598 |
| 616 | American Fork Hospital / Huntsman Intermountain Cancer Center | American Fork | Utah | United States | 84003 |
| 617 | Sandra L Maxwell Cancer Center | Cedar City | Utah | United States | 84720 |
| 618 | Logan Regional Hospital | Logan | Utah | United States | 84321 |
| 619 | Intermountain Medical Center | Murray | Utah | United States | 84107 |
| 620 | McKay-Dee Hospital Center | Ogden | Utah | United States | 84403 |
| 621 | Utah Valley Regional Medical Center | Provo | Utah | United States | 84604 |
| 622 | Saint George Regional Medical Center | Saint George | Utah | United States | 84770 |
| 623 | Utah Cancer Specialists-Salt Lake City | Salt Lake City | Utah | United States | 84106 |
| 624 | Huntsman Cancer Institute/University of Utah | Salt Lake City | Utah | United States | 84112 |
| 625 | LDS Hospital | Salt Lake City | Utah | United States | 84143 |
| 626 | Fredericksburg Oncology Inc | Fredericksburg | Virginia | United States | 22401 |
| 627 | Sentara Cancer Institute at Sentara CarePlex Hospital | Hampton | Virginia | United States | 23666 |
| 628 | Sentara Norfolk General Hospital | Norfolk | Virginia | United States | 23507 |
| 629 | Sentara Virginia Beach General Hospital | Virginia Beach | Virginia | United States | 23454 |
| 630 | MultiCare Auburn Medical Center | Auburn | Washington | United States | 98001 |
| 631 | Overlake Medical Center | Bellevue | Washington | United States | 98004 |
| 632 | Providence Regional Cancer System-Centralia | Centralia | Washington | United States | 98531 |
| 633 | Providence Regional Cancer Partnership | Everett | Washington | United States | 98201 |
| 634 | Saint Francis Hospital | Federal Way | Washington | United States | 98003 |
| 635 | Tacoma/Valley Radiation Oncology Centers-Gig Harbor | Gig Harbor | Washington | United States | 98332 |
| 636 | Providence Regional Cancer System-Lacey | Lacey | Washington | United States | 98503 |
| 637 | Saint Clare Hospital | Lakewood | Washington | United States | 98499 |
| 638 | PeaceHealth Saint John Medical Center | Longview | Washington | United States | 98632 |
| 639 | Providence - Saint Peter Hospital | Olympia | Washington | United States | 98506-5166 |
| 640 | Capital Medical Center | Olympia | Washington | United States | 98507 |
| 641 | MultiCare Good Samaritan Hospital | Puyallup | Washington | United States | 98372 |
| 642 | Tacoma/Valley Radiation Oncology Centers-Puyallup | Puyallup | Washington | United States | 98372 |
| 643 | Cancer Care Northwest - Spokane South | Spokane | Washington | United States | 99202 |
| 644 | Cancer Care Northwest-North Spokane | Spokane | Washington | United States | 99218 |
| 645 | MultiCare Allenmore Hospital | Tacoma | Washington | United States | 98405 |
| 646 | MultiCare Tacoma General Hospital | Tacoma | Washington | United States | 98405 |
| 647 | Northwest Medical Specialties PLLC | Tacoma | Washington | United States | 98405 |
| 648 | Northwest NCI Community Oncology Research Program | Tacoma | Washington | United States | 98405 |
| 649 | Saint Joseph Medical Center | Tacoma | Washington | United States | 98405 |
| 650 | Tacoma/Valley Radiation Oncology Centers-Saint Joe's | Tacoma | Washington | United States | 98405 |
| 651 | PeaceHealth Southwest Medical Center | Vancouver | Washington | United States | 98664 |
| 652 | Compass Oncology Vancouver | Vancouver | Washington | United States | 98684 |
| 653 | Legacy Salmon Creek Hospital | Vancouver | Washington | United States | 98686 |
| 654 | West Virginia University Charleston Division | Charleston | West Virginia | United States | 25304 |
| 655 | West Virginia University Healthcare | Morgantown | West Virginia | United States | 26506 |
| 656 | Wheeling Hospital/Schiffler Cancer Center | Wheeling | West Virginia | United States | 26003 |
| 657 | Langlade Hospital and Cancer Center | Antigo | Wisconsin | United States | 54409 |
| 658 | Marshfield Clinic-Chippewa Center | Chippewa Falls | Wisconsin | United States | 54729 |
| 659 | HSHS Sacred Heart Hospital | Eau Claire | Wisconsin | United States | 54701 |
| 660 | Marshfield Clinic Cancer Center at Sacred Heart | Eau Claire | Wisconsin | United States | 54701 |
| 661 | Green Bay Oncology at Saint Vincent Hospital | Green Bay | Wisconsin | United States | 54301-3526 |
| 662 | Bellin Memorial Hospital | Green Bay | Wisconsin | United States | 54301 |
| 663 | Saint Vincent Hospital Cancer Center Green Bay | Green Bay | Wisconsin | United States | 54301 |
| 664 | Green Bay Oncology Limited at Saint Mary's Hospital | Green Bay | Wisconsin | United States | 54303 |
| 665 | Saint Vincent Hospital Cancer Center at Saint Mary's | Green Bay | Wisconsin | United States | 54303 |
| 666 | Gundersen Lutheran Medical Center | La Crosse | Wisconsin | United States | 54601 |
| 667 | Bay Area Medical Center | Marinette | Wisconsin | United States | 54143 |
| 668 | Marshfield Medical Center-Marshfield | Marshfield | Wisconsin | United States | 54449 |
| 669 | Marshfield Medical Center | Marshfield | Wisconsin | United States | 54449 |
| 670 | Medical College of Wisconsin | Milwaukee | Wisconsin | United States | 53226 |
| 671 | Marshfield Clinic-Minocqua Center | Minocqua | Wisconsin | United States | 54548 |
| 672 | Cancer Center of Western Wisconsin | New Richmond | Wisconsin | United States | 54017 |
| 673 | Saint Vincent Hospital Cancer Center at Oconto Falls | Oconto Falls | Wisconsin | United States | 54154 |
| 674 | Ascension Saint Mary's Hospital | Rhinelander | Wisconsin | United States | 54501 |
| 675 | Saint Mary's Hospital | Rhinelander | Wisconsin | United States | 54501 |
| 676 | Marshfield Medical Center-Rice Lake | Rice Lake | Wisconsin | United States | 54868 |
| 677 | Ascension Saint Michael's Hospital | Stevens Point | Wisconsin | United States | 54481 |
| 678 | Saint Vincent Hospital Cancer Center at Sturgeon Bay | Sturgeon Bay | Wisconsin | United States | 54235-1495 |
| 679 | Green Bay Oncology - Sturgeon Bay | Sturgeon Bay | Wisconsin | United States | 54235 |
| 680 | Aspirus Regional Cancer Center | Wausau | Wisconsin | United States | 54401 |
| 681 | Marshfield Clinic-Wausau Center | Wausau | Wisconsin | United States | 54401 |
| 682 | Diagnostic and Treatment Center | Weston | Wisconsin | United States | 54476 |
| 683 | Marshfield Medical Center - Weston | Weston | Wisconsin | United States | 54476 |
| 684 | Marshfield Clinic - Wisconsin Rapids Center | Wisconsin Rapids | Wisconsin | United States | 54494 |
| 685 | Rocky Mountain Oncology | Casper | Wyoming | United States | 82609 |
| 686 | Welch Cancer Center | Sheridan | Wyoming | United States | 82801 |
| 687 | Hospital Univ. Erasme | Brussels | Belgium | 1070 | |
| 688 | University Hospital Saint Luc | Brussels | Belgium | 1200 | |
| 689 | Algemeen Ziekenhuis Groeninge Campus Kennedylaan | Kortrijk | Belgium | 8500 | |
| 690 | AZ Turnhout-Campus Saint Elizabeth | Turnhout | Belgium | 2300 | |
| 691 | London Regional Cancer Program | London | Ontario | Canada | N6A 4L6 |
| 692 | Ottawa Hospital and Cancer Center-General Campus | Ottawa | Ontario | Canada | K1H 8L6 |
| 693 | Ottawa Hospital-Civic Campus | Ottawa | Ontario | Canada | K1Y 4E9 |
| 694 | CHUM - Hopital Notre-Dame | Montreal | Quebec | Canada | H2L 4M1 |
| 695 | CHUM - Centre Hospitalier de l'Universite de Montreal | Montreal | Quebec | Canada | H2X 3E4 |
| 696 | Rabin Medical Center | Petach Tikva | Israel | 49100 | |
| 697 | Tel Aviv Sourasky Medical Center | Tel Aviv | Israel | 64239 | |
| 698 | Chaim Sheba Medical Center | Tel Hashomer | Israel | 52621 |
Sponsors and Collaborators
- National Cancer Institute (NCI)
- NRG Oncology
Investigators
- Principal Investigator: Ross A Abrams, NRG Oncology
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
National Cancer Institute (NCI)
ClinicalTrials.gov Identifier:
NCT01013649
Other Study ID Numbers:
- NCI-2011-01987
- NCI-2011-01987
- 11-00773
- CDR0000659092
- RTOG 0848
- RTOG-0848
- RTOG-0848
- U10CA180830
- U10CA180868
- U10CA021661
First Posted:
Nov 16, 2009
Last Update Posted:
Aug 18, 2022
Last Verified:
Apr 1, 2022
Additional relevant MeSH terms: