Relation Between Femoral Nerve Conduction Velocity and Its Mechanosensitivity Changes Among Patellofemoral Pain Syndrome

Sponsor
Cairo University (Other)
Overall Status
Not yet recruiting
CT.gov ID
NCT04624542
Collaborator
(none)
60
8

Study Details

Study Description

Brief Summary

  1. to investigate the relation between NCV of femoral nerve and other dependent variables such as ( pain & limited hip extension ROM )in patients with PFPS .

  2. to predict using the NCV as a method for assessment femoral nerve mechanosensitivity in those with PFPS

Condition or Disease Intervention/Treatment Phase
  • Device: Electromyographic device

Detailed Description

Patellofemoral pain syndrome (PFPS) is considered one of the most common condition affecting young active populations, it accounts for about 40% of individuals complaining from knee pain.PFPS is the anterior or retro patellar pain that can be precipitated by some daily activities such as ascending and descending stairs, kneeling, squatting or performing everyday tasks. Individuals with PFPS can experience a history of cracking or popping sounds when changing position or climbing stairs and also experience pain during repeated knee flexion. In a previous study conducted by Jensen et al .(2008),they observed that individuals with PFPS experienced symptoms that are related to neural compromise like patellar numbness and reduced ability to differentiate between different thermal stimulus .so PFPS may be related to neurological impairments or dysfunction.

Femoral slump test can be used in examining the neurodynamic responses in individuals with anterior knee pain which has a specificity of more than 75% in testing neural mechanosensitivity In a study conducted by Lin et al (2014) that examine the hip extension range of motion (ROM) and mechanical sensitivity of femoral nerve as a neurodynamic response in individuals with PFPS , they proposed that 30% of them have decrease hip extension ROM and increased mechanosensitivity comparison with healthy individuals. The current management of the patellofemoral pain support using open- and closed-chain exercises, strengthening, stretching, aerobic exercise, patellofemoral and tibiofemoral mobilizations, patellar taping, highintensity NMES, neuromuscular training, and gait retraining as a multi modal treatment for PFPS. Despite these methods result in significant improvement, other few patients reported some residual symptoms Hung et al .,(2015) have encouraged that using the femoral nerve mobilization as a neurodynamic management for treating PFPS patients especially those with postive femoral slump test , and testing the hip extension range of motion as a reference of improvement previous studies reported the presence of neurogenic dysfunction model to PFPS but most of these scientific researches lack the presence of the gold standard and objective method for identifying the neurogenic patellofemoral pain

Study Design

Study Type:
Observational [Patient Registry]
Anticipated Enrollment :
60 participants
Observational Model:
Other
Time Perspective:
Cross-Sectional
Official Title:
Relation Between Femoral Nerve Conduction Velocity and Its Mechanosensitivity Changes Among Individual With Patellofemoral Pain Syndrome
Anticipated Study Start Date :
Dec 1, 2020
Anticipated Primary Completion Date :
Jun 1, 2021
Anticipated Study Completion Date :
Aug 1, 2021

Arms and Interventions

Arm Intervention/Treatment
group 1

Thirty individuals diagnosed with unilateral chronic PFPS from both genders and age between 18-35 years who will be referred from an orthopedic surgeon.

Device: Electromyographic device
the EMG machine will be used to measure NCV of femoral nerve within individuals with PFPS

control group

-30 healthy active individuals ranging from 18-36 yrs as a controlled group

Device: Electromyographic device
the EMG machine will be used to measure NCV of femoral nerve within individuals with PFPS

Outcome Measures

Primary Outcome Measures

  1. the patellofemoral pain [6 months]

    pain will be measured by using the Pain numeric rating scale (NRS)

Secondary Outcome Measures

  1. range of hip extension [6 month]

    ROM will be measured using universal goniometer

Eligibility Criteria

Criteria

Ages Eligible for Study:
18 Years to 36 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
  • The inclusion criteria screened by the clinicians was pain during patellar palpation. In addition, subjects needed to fulfill all of the following requirements to be included in the PFP group:
  1. Patient reporting symptoms of insidious onset and duration of at least 1 month (de Oliveira et al .,2016)

  2. Peri- or retropatellar pain during at least 2 of the following activities: squatting, prolonged sitting, kneeling, running, jumping and climbing stairs (Vegstein et al., 2019)

  3. Worst pain level in the previous month of up to 3cm on a 10cm numerical rating scale (NRS). (de Oliveira et al .,2016)

  4. BMI 25-30 kg/cm2 (Nouri F et al .,2019)

  5. Showing 2 or more positive signs on the following clinical tests:

Clarke's sign, Waldron test, active patellar grind test, patellar compression test ,and palpation of the medial/lateral articular border of the patella.(hung et al., 2015) To be included in the control group CG, participants could not present any signs or symptoms of PFP or other musculoskeletal conditions

Exclusion Criteria:
    1. inflammatory process of lower limb (Lin et al., 2014 ) 2) patellar tendon or meniscus tears (hung et al., 2015) 3) bursitis and ligament tears (hung et al., 2015)
  1. Those who had undergone knee surgery, oral steroids and knee injection were excluded from this study (Vegstein et al., 2019) 5) lower back dysfunction such as disc lesion , sciatica or spondylolisthesis (Lin et al., 2014 ) 6) participants that had undergone physiotherapy during the preceding 6 months (de Oliveira et al .,2016)

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

  • Cairo University

Investigators

  • Study Director: nabil ab abdo, PHD faculty of physical therapy Cairo university

Study Documents (Full-Text)

None provided.

More Information

Publications

Responsible Party:
Nabil Abdo Abdellah Mohamed, lecturer of orthopedic physiotherapy /faculty of physical therapy cairo university, Cairo University
ClinicalTrials.gov Identifier:
NCT04624542
Other Study ID Numbers:
  • NCV for PFPS
First Posted:
Nov 12, 2020
Last Update Posted:
Nov 12, 2020
Last Verified:
Nov 1, 2020
Individual Participant Data (IPD) Sharing Statement:
Undecided
Plan to Share IPD:
Undecided
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Keywords provided by Nabil Abdo Abdellah Mohamed, lecturer of orthopedic physiotherapy /faculty of physical therapy cairo university, Cairo University
Additional relevant MeSH terms:

Study Results

No Results Posted as of Nov 12, 2020