Patient Characteristics, Feasibility, and Outcomes of a Home Mechanical Ventilation Program in a Developing Country
Study Details
Study Description
Brief Summary
This study aims to describe the patient characteristics, feasibility, and outcomes of an home mechanical ventilation (HMV) program at a university hospital in Thailand.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
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Detailed Description
Data will be collected on all patients who were discharged with HMV between October 2014 and August 2015 at Thammasat University Hospital. Data include sex, age, co-morbid diseases, clinical features, causes of HMV, mechanical ventilator and complimentary equipment characteristics, caregiver characteristics, ventilator and patient care costs, and morbidity and mortality outcomes of patients.
Study Design
Outcome Measures
Primary Outcome Measures
- Mortality rate of HMV patients [Up to 1 year]
The number of deaths among HMV patients is recorded during follow-up period (up to 1 year)
Secondary Outcome Measures
- Healthcare home visit [Up to 1 year]
Record the number of healthcare home visits (events)
- Caregiver characteristics [Up to 1 year]
Record the number of caregivers per patient, the number of well-trained caregivers
- Family characteristics [Upto 1 year]
Record types (relationships) and the number of family members, income to costs ratio
- HMV complications due to tracheobronchitis [Up to 1 year]
Record the number of tracheobronchitis (events) and the number of hospitalizations due to their effects
- HMV complications due to ventilator-associated pneumonia [Up to 1 year]
Record the number of ventilator-associated pneumonias (events) and the number of hospitalizations due to their effects
- HMV complications due to the loose tracheostomy [Up to 1 year]
Record the number of loose tracheostomies (events) and the number of hospitalizations due to their effects
- HMV complications due to the granulation-tissue formation at tracheostomy [Up to 1 year]
Record the number of granulation-tissue formations at tracheostomy (events) and the number of hospitalizations due to their effects
- HMV complications due to pneumothorax [Up to 1 year]
Record the number of pneumothoraces (events) and the number of hospitalizations due to their effects
- HMV complications due to the ventilator malfunction [Up to 1 year]
The number of ventilator malfunctions (events) and the number of hospitalizations due to their effects
Eligibility Criteria
Criteria
Inclusion Criteria:
- All hospitalized patients requiring mechanical ventilation aged 18 or more years.
Exclusion Criteria:
- None.
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Department of Medicine, Faculty of Medicine, Thammasat University | Pathumthani | Thailand | 12120 |
Sponsors and Collaborators
- Thammasat University
Investigators
- Principal Investigator: Narongkorn Saiphoklang, MD, Faculty of Medicine, Thammasat University
Study Documents (Full-Text)
None provided.More Information
Publications
- Divo MJ, Murray S, Cortopassi F, Celli BR. Prolonged mechanical ventilation in Massachusetts: the 2006 prevalence survey. Respir Care. 2010 Dec;55(12):1693-8.
- Hazenberg A, Kerstjens HA, Prins SC, Vermeulen KM, Wijkstra PJ. Initiation of home mechanical ventilation at home: a randomised controlled trial of efficacy, feasibility and costs. Respir Med. 2014 Sep;108(9):1387-95. doi: 10.1016/j.rmed.2014.07.008. Epub 2014 Jul 22.
- Heinemann F, Budweiser S, Jörres RA, Arzt M, Rösch F, Kollert F, Pfeifer M. The role of non-invasive home mechanical ventilation in patients with chronic obstructive pulmonary disease requiring prolonged weaning. Respirology. 2011 Nov;16(8):1273-80. doi: 10.1111/j.1440-1843.2011.02054.x.
- Kurek CJ, Cohen IL, Lambrinos J, Minatoya K, Booth FV, Chalfin DB. Clinical and economic outcome of patients undergoing tracheostomy for prolonged mechanical ventilation in New York state during 1993: analysis of 6,353 cases under diagnosis-related group 483. Crit Care Med. 1997 Jun;25(6):983-8.
- Lone NI, Walsh TS. Prolonged mechanical ventilation in critically ill patients: epidemiology, outcomes and modelling the potential cost consequences of establishing a regional weaning unit. Crit Care. 2011;15(2):R102. doi: 10.1186/cc10117. Epub 2011 Mar 27.
- MacIntyre NR, Epstein SK, Carson S, Scheinhorn D, Christopher K, Muldoon S; National Association for Medical Direction of Respiratory Care. Management of patients requiring prolonged mechanical ventilation: report of a NAMDRC consensus conference. Chest. 2005 Dec;128(6):3937-54.
- McKim DA, Road J, Avendano M, Abdool S, Cote F, Duguid N, Fraser J, Maltais F, Morrison DL, O'Connell C, Petrof BJ, Rimmer K, Skomro R; Canadian Thoracic Society Home Mechanical Ventilation Committee. Home mechanical ventilation: a Canadian Thoracic Society clinical practice guideline. Can Respir J. 2011 Jul-Aug;18(4):197-215.
- Oktem S, Ersu R, Uyan ZS, Cakir E, Karakoc F, Karadag B, Kiyan G, Dagli E. Home ventilation for children with chronic respiratory failure in Istanbul. Respiration. 2008;76(1):76-81. Epub 2007 Nov 6.
- Sanjuán-López P, Valiño-López P, Ricoy-Gabaldón J, Verea-Hernando H. Amyotrophic lateral sclerosis: impact of pulmonary follow-up and mechanical ventilation on survival. A study of 114 cases. Arch Bronconeumol. 2014 Dec;50(12):509-13. doi: 10.1016/j.arbres.2014.04.010. Epub 2014 Jun 12. English, Spanish.
- Simonds AK. Risk management of the home ventilator dependent patient. Thorax. 2006 May;61(5):369-71.
- Tagami M, Kimura F, Nakajima H, Ishida S, Fujiwara S, Doi Y, Hosokawa T, Yamane K, Unoda K, Hirose T, Tani H, Ota S, Ito T, Sugino M, Shinoda K, Hanafusa T. Tracheostomy and invasive ventilation in Japanese ALS patients: decision-making and survival analysis: 1990-2010. J Neurol Sci. 2014 Sep 15;344(1-2):158-64. doi: 10.1016/j.jns.2014.06.047. Epub 2014 Jul 1.
- MTU-EC-IM-6-146/57