APRIL: Analysis of the Persistence, Reservoir and HIV Latency
Sponsor
University Hospital, Strasbourg, France (Other)
Overall Status
Not yet recruiting
CT.gov ID
NCT05752318
Collaborator
(none)
500
47.9
Study Details
Study Description
Brief Summary
The APRIL study aims at analyzing HIV reservoirs, latency and persistence on antiretroviral therapy. It enrolls HIV-infected adults providing blood samples of which peripheral blood mononuclear cells are stored. The frequency, phenotype and inducibility of HIV-infected cells are then analyzed. These parameters may vary across the different clinical and therapeutic settings.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
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Study Design
Study Type:
Observational
Anticipated Enrollment
:
500 participants
Observational Model:
Cohort
Time Perspective:
Prospective
Official Title:
APRIL Study: Analysis of the Persistence, Reservoir and HIV Latency
Anticipated Study Start Date
:
Feb 27, 2023
Anticipated Primary Completion Date
:
Jan 25, 2027
Anticipated Study Completion Date
:
Feb 25, 2027
Outcome Measures
Primary Outcome Measures
- HIV-Flow [1 day]
Eligibility Criteria
Criteria
Ages Eligible for Study:
18 Years
and Older
Sexes Eligible for Study:
All
Inclusion Criteria:
-
HIV-infection
-
Adults (>18 years)
-
Social insurance
-
Informed consent
Exclusion Criteria:
-
HIV-uninfected
-
<18 years
-
Lack of social insurance
-
Lack or withdraw of consent
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- University Hospital, Strasbourg, France
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
University Hospital, Strasbourg, France
ClinicalTrials.gov Identifier:
NCT05752318
Other Study ID Numbers:
- 8825
First Posted:
Mar 2, 2023
Last Update Posted:
Mar 2, 2023
Last Verified:
Jan 1, 2023