APRIL: Analysis of the Persistence, Reservoir and HIV Latency

Sponsor
University Hospital, Strasbourg, France (Other)
Overall Status
Not yet recruiting
CT.gov ID
NCT05752318
Collaborator
(none)
500
47.9

Study Details

Study Description

Brief Summary

The APRIL study aims at analyzing HIV reservoirs, latency and persistence on antiretroviral therapy. It enrolls HIV-infected adults providing blood samples of which peripheral blood mononuclear cells are stored. The frequency, phenotype and inducibility of HIV-infected cells are then analyzed. These parameters may vary across the different clinical and therapeutic settings.

Condition or Disease Intervention/Treatment Phase

    Study Design

    Study Type:
    Observational
    Anticipated Enrollment :
    500 participants
    Observational Model:
    Cohort
    Time Perspective:
    Prospective
    Official Title:
    APRIL Study: Analysis of the Persistence, Reservoir and HIV Latency
    Anticipated Study Start Date :
    Feb 27, 2023
    Anticipated Primary Completion Date :
    Jan 25, 2027
    Anticipated Study Completion Date :
    Feb 25, 2027

    Outcome Measures

    Primary Outcome Measures

    1. HIV-Flow [1 day]

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years and Older
    Sexes Eligible for Study:
    All
    Inclusion Criteria:
    • HIV-infection

    • Adults (>18 years)

    • Social insurance

    • Informed consent

    Exclusion Criteria:
    • HIV-uninfected

    • <18 years

    • Lack of social insurance

    • Lack or withdraw of consent

    Contacts and Locations

    Locations

    No locations specified.

    Sponsors and Collaborators

    • University Hospital, Strasbourg, France

    Investigators

    None specified.

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    University Hospital, Strasbourg, France
    ClinicalTrials.gov Identifier:
    NCT05752318
    Other Study ID Numbers:
    • 8825
    First Posted:
    Mar 2, 2023
    Last Update Posted:
    Mar 2, 2023
    Last Verified:
    Jan 1, 2023
    Keywords provided by University Hospital, Strasbourg, France

    Study Results

    No Results Posted as of Mar 2, 2023