POCUS Sepsis: Point of Care Ultrasound to Predict Intensive Care Unit Admission of Patients Presenting With Sepsis to the Emergency Department
Study Details
Study Description
Brief Summary
The FloPatch device will be applied to 150 septic patients in the emergency department before they receive fluid resuscitation. This study will assess whether initial FloPatch measured volume-responsiveness and volume of fluids used will predict a composite outcome of mortality, intensive care unit admission, or rapid response team activation. The development of fluid unresponsiveness throughout the initial fluid resuscitation will be assessed and its association with the composite outcome will be assessed.
Condition or Disease | Intervention/Treatment | Phase |
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Study Design
Arms and Interventions
Arm | Intervention/Treatment |
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Mortality, ICU admission, or rapid response team activation Carotid flow patterns and velocity time integral values, as determined by FloPatch. |
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No mortality, ICU admission, or rapid response team activation Carotid flow patterns and velocity time integral values, as determined by FloPatch. |
Outcome Measures
Primary Outcome Measures
- Mortality [24 hours]
This study will ascertain whether the patient died within 24 hours of ED arrival.
- ICU admission [24 hours]
This study will ascertain whether the patient was admitted to the ICU within 24 hours of ED arrival.
- Rapid response team activation [24 hours]
This study will ascertain whether a rapid response team was activated for the patient within 24 hours of ED arrival.
Eligibility Criteria
Criteria
Inclusion Criteria:
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Emergency department patient
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18+ years old
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Systolic blood pressure less than 100mmHg
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Respiratory rate greater than 22 breaths per minutes
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Temperature greater than 38 degrees Celsius or less than 36 degrees Celsius
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Heart rate greater than 90 beats per minute
Exclusion Criteria:
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Already intubated prior to emergency department arrival
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Ventilator-dependent
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Patients transferred from another hospital
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Pregnancy
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
---|---|---|---|---|---|
1 | North Shore University Hospital | Manhasset | New York | United States | 11030 |
Sponsors and Collaborators
- Northwell Health
- Flosonics Medical
Investigators
- Principal Investigator: Allison Cohen, MD, North Shore University Hospital
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- 20-0151