PASS: Polymyalgia Rheumatica Associated to Primary Sjogren Syndrome
Study Details
Study Description
Brief Summary
To determine the phenotype of patients having PMR symptoms and primary Sjogren syndrome (pSS), we used a French national call to identify patients combining both diseases and collected retrospective clinical and biological data.
Condition or Disease | Intervention/Treatment | Phase |
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Detailed Description
A national call to identify patients combining pSS and PMR was disseminated in France. Patients with Sjögren's syndrome associated with rheumatoid arthritis were excluded. We described the global population having both diseases and compared them to two historic prospective cohorts of isolated pSS (the prospective cohort of primary Sjögren DiapSS), or isolated PMR (TENOR, a cohort of recent PMR), regarding clinical, imaging and treatments characteristics.
Study Design
Outcome Measures
Primary Outcome Measures
- clinical data [at diagnosis]
pain (pain scale)
- biological data [at diagnosis]
biology (CRP in mg/L)
- biological data [at diagnosis]
presence of anti-SSA/SSB (yes/no)
- histological data [at diagnosis]
accesories salivary glands biopsies (focus score)
- imaging data [at diagnosis]
US (presence of shoulder involvement yes/no; hip involvement yes/no)
- treatments data [at inclusion ( day 0)]
use of methotrexate yes/no; abatacept yes/no, rituximab yes/no, corticosteroids yes/no; pilocarpine yes/no; hydroxychloroquine yes/no
Eligibility Criteria
Criteria
Inclusion Criteria:
- fulfilling the ACR/EULAR 2012 criteria for PMR and the ACR/EULAR 2016 criteria for pSS
Exclusion Criteria:
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
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1 | CHRU Brest | Brest | France | 29200 |
Sponsors and Collaborators
- University Hospital, Brest
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- PASS (29BRC20.0176)