Comparing Postoperative Analgesic Effects of Intrathecal Morphine and Bilateral Erector Spina Plane Block in Elective Cesarean Sections
Study Details
Study Description
Brief Summary
Cesarean section cause severe pain due to surgical incision, abdominal wall retraction and visceral organ movements. Cesarean section can be performed with general anesthesia, spinal anesthesia, epidural anesthesia and combined spinal epidural anesthesia methods.
Because of the possibility of aspiration pneumonia in pregnant women are under general anesthesia, the awareness of anesthesia in the mother during the operation due to insufficient anesthesia, unsuccessful intubation, respiratory complications in the mother and newborn and low APGAR scores, regional anesthesia is superior to general anesthesia in elective cesarean section operations.
Spinal anesthesia, abdominal wall blocks such as erector spinae plane block, parenteral and intrathecal opioids may be used for postoperative analgesia in cesarean section operations.
Intrathecal morphine can cause postoperative nausea-vomiting, itching, respiratory depression. Erector spina plane block can provide effective pain control and reduce opioid consumption.
The primary implication of this study is to compare postoperative pain scores and opioid consumption on elective cesarean section patients under spinal anesthesia with intrathecal morphine or erector spina block in addition to spinal anesthesia.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
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Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Intrathecal Morphine Group Prosedure/Surgery: Regional block and Intrathecal Morphine Comparison Comparing postoperative pain and opioid consumption in groups |
|
| Bilateral Erector Spinae Plane Block Group Prosedure/Surgery: Regional block and Intrathecal Morphine Comparison Comparing postoperative pain and opioid consumption in groups |
Outcome Measures
Primary Outcome Measures
- Pain Scores [24 hours]
Comparing pain scores with Numeric Rating Scale (NRS)
- Opioid Consumption [24 hours]
Comparing opioid consumption via Patient Controlled Analgesia (PCA) device
Secondary Outcome Measures
- Participant satisfaction [24 hours]
Comparing pain with numeric rating scale (NRS)
- Apgar scores of newborns [1st and 5th minute after the delivery]
APGAR (Activity, Pulse, Grimace, Appearance, Respiration) scores may be effected by intrathecal morphine
- Side effects of medications [24 hours]
İntravenous and intrathecal opioid can cause nausea-vomiting, respirator depression, itching
Eligibility Criteria
Criteria
Inclusion Criteria:
- Patients between 18 and 40 years old, ASA (American Society of Anesthesiologists) score I-II, undergoing elective cesarean section
Exclusion Criteria:
-
The patients with major hepatic, cardiovascular or renal disease
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The patients for whom spinal anesthesia is contraindicated
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The patients who is allergic to any drugs that we use for this study
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Marmara University School of Medicine | Istanbul | Turkey | ||
| 2 | Marmara University | Istanbul | Turkey |
Sponsors and Collaborators
- Marmara University
Investigators
- Study Chair: Beliz Bilgili, Marmara University
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- MarmaraMedical