Postoperative Cognitive Dysfunction in Heart Surgery

Sponsor
Kocaeli University (Other)
Overall Status
Completed
CT.gov ID
NCT05406843
Collaborator
(none)
140
1
19
7.4

Study Details

Study Description

Brief Summary

To determine the rate of Postoperative Cognitive Dysfunction (POCD) in the early and late postoperative periods by comparing the preop and postop period mini mental status tests in participants undergoing open heart surgery, and to compare the results of the investgators clinic with the world literature.

Condition or Disease Intervention/Treatment Phase
  • Other: Preoperative cognitive functions of participants undergoing open heart surgery
  • Other: Postoperative cognitive functions of particiants undergoing open heart surgery

Detailed Description

Postoperative delirium (POD) and Cognitive Dysfunction (POCD) are changes in mental status, especially in the geriatric surgery population.Unlike other forms of delirium, POD results in early full recovery.Postoperative Cognitive Dysfunction (POCD) is more difficult to define and implies temporal consciousness impairment associated with surgery.

While the diagnosis of delirium requires the detection of symptoms, the diagnosis of POCD requires preoperative neuropsychological testing and determining how much reduction will mean cognitive dysfunction. Postoperative delirium management is complex and requires multiple strategies. Methods of treating and preventing POCD are still uncertain.It is known that POCD is most commonly seen in patients undergoing open heart surgery.In this study, the investigators aim is to evaluate whether there is any change in cognitive status in the postoperative period compared to the preoperative period of participants who will undergo open heart surgery due to valve pathology or coronary stenosis.

Study Design

Study Type:
Observational
Actual Enrollment :
140 participants
Observational Model:
Other
Time Perspective:
Retrospective
Official Title:
Postoperative Cognitive Dysfunction in Participants Undergoing Open Heart Surgery
Actual Study Start Date :
Jan 1, 2020
Actual Primary Completion Date :
Jan 1, 2021
Actual Study Completion Date :
Aug 1, 2021

Arms and Interventions

Arm Intervention/Treatment
Preoperative cognitive status of participants undergoing open heart surgery

Detection of postoperative cognitive impairment is difficult and it starts with testing in the preoperative period. In this study, it was aimed to determine postoperative cognitive impairment by comparing cognitive functions by using Minimental status test in the preoperative period in participants scheduled for open heart surgery for one year. It was planned to compare the obtained data in terms of participants undergoing valve and coronary bypass surgery, age, gender, diabetes, kidney disease, chronic obstructive pulmonary disease (COPD), surgical characteristics, bypass time, and crossclamping time.

Other: Preoperative cognitive functions of participants undergoing open heart surgery
Surgery times and cross-clamping times of the participants who will undergo open heart surgery were recorded.

Postoperative cognitive status of participants undergoing open heart surgery

Detection of postoperative cognitive impairment is difficult and it starts with testing in the preoperative period. In this study, it was aimed to determine the postoperative cognitive impairment by comparing it with the cognitive functions in the preoperative period using the Minimental status test in the postoperative period in participants scheduled for open heart surgery for a year. It was planned to compare the obtained data in terms of participants undergoing valve and coronary bypass surgery, age, gender, diabetes, kidney disease, chronic obstructive pulmonary disease (COPD), surgical characteristics, bypass time, and crossclamping time.

Other: Postoperative cognitive functions of particiants undergoing open heart surgery
Changes in mini mental test scores were recorded in the postoperative period.

Outcome Measures

Primary Outcome Measures

  1. Evaluation of postoperative cognitive functions in participants undergoing open heart surgery. [1 year]

    The aim is to understand whether there is a loss of cognitive functions in the postoperative period, according to the preoperative periods, by testing the participants with open heart surgery on the 3rd day, 7th day, and 2nd month after the surgery.

Secondary Outcome Measures

  1. Comparison with the literature. [1 year]

    Comparison of the results in the investigators clinic with the literature.

Eligibility Criteria

Criteria

Ages Eligible for Study:
18 Years to 75 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
  • 18-75 age

  • American Society of Anesthesiologists (ASA) II-III

Exclusion Criteria:
  • 75 age

  • <18 age

  • Patients who died within 48 hours after the operation

Contacts and Locations

Locations

Site City State Country Postal Code
1 Kocaeli Üniversitesi Tıp Fakültesi Hastanesi Kocaeli İzmit Turkey 41100

Sponsors and Collaborators

  • Kocaeli University

Investigators

  • Study Director: Tülay Çardaközü, Kocaeli University

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Huri Yeşildal, Assistant, Kocaeli University
ClinicalTrials.gov Identifier:
NCT05406843
Other Study ID Numbers:
  • Observational
First Posted:
Jun 7, 2022
Last Update Posted:
Jun 9, 2022
Last Verified:
Jun 1, 2022
Individual Participant Data (IPD) Sharing Statement:
Yes
Plan to Share IPD:
Yes
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Keywords provided by Huri Yeşildal, Assistant, Kocaeli University
Additional relevant MeSH terms:

Study Results

No Results Posted as of Jun 9, 2022