Late Onset Postoperative Nausea and Vomiting
Sponsor
King Khaled Eye Specialist Hospital (Other)
Overall Status
Completed
CT.gov ID
NCT00918190
Collaborator
(none)
75
1
3
18
4.2
Study Details
Study Description
Brief Summary
The purpose of this trial is to study the effects of different combinations of antiemetics on the incidence of late onset postoperative nausea and vomiting.
Condition or Disease | Intervention/Treatment | Phase |
---|---|---|
|
N/A |
Detailed Description
The authors will study the effect of many antiemetics on the occurrence of nausea and vomiting following strabismus surgery in pediatrics.
Study Design
Study Type:
Interventional
Anticipated Enrollment
:
75 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Masking:
Double (Participant, Care Provider)
Primary Purpose:
Prevention
Official Title:
Late Onset Postoperative Nausea and Vomiting Following Strabismus Surgery in Pediatric.What Combination is Better
Study Start Date
:
Jun 1, 2009
Actual Primary Completion Date
:
Dec 1, 2010
Actual Study Completion Date
:
Dec 1, 2010
Arms and Interventions
Arm | Intervention/Treatment |
---|---|
Active Comparator: Ondansetron-Dexa group Use 2 different antiemetics |
Drug: Ondansetron, Dexamethasone
Use of ondansetron and dexamethasone as combined antiemetics
Other Names:
|
Active Comparator: Midazolam, Dexa group use of midazolam and dexamethasone |
Drug: Midazolam, dexamethasone
use of midazolam and dexamethasone as combined antiemetic
Other Names:
|
Placebo Comparator: Placebo Saline will be given |
Drug: Placebo
Saline
Other Names:
|
Outcome Measures
Primary Outcome Measures
- Efficacy of antiemetics combination [3 days]
Eligibility Criteria
Criteria
Ages Eligible for Study:
4 Years
to 12 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
- children undergoing elective strabismus surgery under general anesthesia
Exclusion Criteria:
-
children experienced retching or vomiting
-
children who have taken anti-emetic medications, antihistaminics, steroids, or psychoactive drugs within 24 hours before surgery
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
---|---|---|---|---|---|
1 | king Khaled Eye Specialist hospital | Riyadh | Saudi Arabia | 11462 |
Sponsors and Collaborators
- King Khaled Eye Specialist Hospital
Investigators
- Principal Investigator: Waleed Riad, MD, AB, SB, King Khaled Eye Specialist Hospital
Study Documents (Full-Text)
None provided.More Information
Publications
Responsible Party:
King Khaled Eye Specialist Hospital
ClinicalTrials.gov Identifier:
NCT00918190
Other Study ID Numbers:
- RP 0917
First Posted:
Jun 11, 2009
Last Update Posted:
Oct 19, 2021
Last Verified:
Oct 1, 2021
Keywords provided by King Khaled Eye Specialist Hospital
Additional relevant MeSH terms: