Melatonin and Its Effect on the Perioperative Opioid Needs in Pediatric Patients Undergoing Laparoscopic Surgery.
Study Details
Study Description
Brief Summary
To study the role of Preoperative Melatonin adminsteration in pediatric patients undergoing laparoscopic surgeries regarding its analgesic and sedative effects
Condition or Disease | Intervention/Treatment | Phase |
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N/A |
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
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Active Comparator: Group A patients undergoing abdominal surgery receiving melatonin |
Drug: Melatonin 3 MG
Preopertive melatonin adminstration oral 0.2 mg /kg 45 min before general anaethesia.
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Placebo Comparator: Group B control group |
Other: Placebo
Placebo medication will be given to control group
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Outcome Measures
Primary Outcome Measures
- Postoperative pain [Discharge from postanesthesia care unit (1 hour)]
Assesment of pain will be done using Face, Leg, Activity , Crying and Consolability behavioural pain scale (FLACC), Each category is scored on the 0-2 scale, which results in a total score of 0-10. 0 = Relaxed and comfortable, 1-3 = Mild discomfort, 4-6 = Moderate pain and 7-10 = Severe discomfort or pain or both.
Eligibility Criteria
Criteria
Inclusion Criteria:
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Age from 2 to 10 years.
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Sex: Both sexes.
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Patients with ASA classificaion I and II.
Exclusion Criteria:
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Declining to give written informed consent.
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History of allergy to the medications used in the study.
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psychiatric disorder.
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ASA classification III-V.
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Fever ,cough , asthma or upper respiratory tract infection, neuromuscular disorders, spine abnormalities.
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Anticipated difficult airway .
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History of malignant hyperthermia
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
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1 | Ain shams university hospital | Cairo | Abbasia | Egypt | 11213 |
Sponsors and Collaborators
- Ain Shams University
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- FAMSU R264/2022