Predictive Value of Inflammatory Indexes and CHA2DS2-VASc Score for LVT in ANT-MI With Left Ventricular Dysfunction

Sponsor
Henan Provincial People's Hospital (Other)
Overall Status
Completed
CT.gov ID
NCT04871126
Collaborator
(none)
371
84

Study Details

Study Description

Brief Summary

To investigate the predictive value of inflammatory indexes and CHA2DS2-VASc score for anterior myocardial infarction (ANT-MI) with left ventricular thrombus(LVT) (LVT).

Condition or Disease Intervention/Treatment Phase
  • Other: inflammatory indexes and CHA2DS2-VASc score

Detailed Description

The clinical data were collected from 371consecutive patients with ANT-MI in our hospital from January 2014 to January 2021.As a result,totally 62 patients with LVT were selected as the experimental group and 186 patients with non-LVT as the control group .The observation indexes included baseline data, coronary angiography, disease course, laboratory examination and auxiliary examination.Patients with severe organic disease and having previous history of left ventricular aneurysm( LVA) and LVT were excluded.Data was analyzed by software SPSS 22.0 for statistical analysis,and the logistic regression model was established.A P<0.05 was considered statistically significant, and the risk factors of LVT formation were retrospectively analyzed.

Study Design

Study Type:
Observational
Actual Enrollment :
371 participants
Observational Model:
Cohort
Time Perspective:
Retrospective
Official Title:
Predictive Value of Inflammatory Indexes and CHA2DS2-VASc Score for Left Ventricular Thrombus in Acute Anterior Myocardial Infarction With Left Ventricular Dysfunction
Actual Study Start Date :
Jan 1, 2014
Actual Primary Completion Date :
Jan 1, 2021
Actual Study Completion Date :
Jan 1, 2021

Arms and Interventions

Arm Intervention/Treatment
LVT group

left ventricular thrombus in acute anterior myocardial infarction patients with left ventricular dysfunction

Other: inflammatory indexes and CHA2DS2-VASc score
inflammatory indexes and CHA2DS2-VASc score

non-LVTgroup

acute anterior myocardial infarction patients with left ventricular dysfunction while without LVT

Other: inflammatory indexes and CHA2DS2-VASc score
inflammatory indexes and CHA2DS2-VASc score

Outcome Measures

Primary Outcome Measures

  1. the predictive of the inflammatory indexes and CHA2DS2-VASc score in LVT [Day 1]

    the logistic regression model was established between the indexes and LVT

Eligibility Criteria

Criteria

Ages Eligible for Study:
18 Years to 80 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:

acute anterior myocardial infarction with left ventricular dysfunction

Exclusion Criteria:

end-stage organic disease, thrombotic hematological disorders, previous anticoagulant use, and poor echogenicity

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

  • Henan Provincial People's Hospital

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Henan Provincial People's Hospital
ClinicalTrials.gov Identifier:
NCT04871126
Other Study ID Numbers:
  • CHA2DS2-VASc score
First Posted:
May 4, 2021
Last Update Posted:
May 4, 2021
Last Verified:
Apr 1, 2021
Individual Participant Data (IPD) Sharing Statement:
Undecided
Plan to Share IPD:
Undecided
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Keywords provided by Henan Provincial People's Hospital
Additional relevant MeSH terms:

Study Results

No Results Posted as of May 4, 2021