Melatonin Versus Hydroxizin for Pre Operative Anxiety in Elderly Patients With Hip Fracture
Study Details
Study Description
Brief Summary
prospective randomized trial including adukt patients scheduled for hip fracture surgery, Randomization into 2 groups: Group A: Hydroxizin peroperatively Group B: Melatonin pre operatively
Condition or Disease | Intervention/Treatment | Phase |
---|---|---|
|
N/A |
Detailed Description
prospective randomized trial including adukt patients scheduled for hip fracture surgery, Randomization into 2 groups: Group A: Hydroxizin peroperatively Group B: Melatonin pre operatively
Non inclusion criteria: patients with severe cognitive impairement Primary outcome pre operative anxiety assessed with Amsterdam preoperative anxiety and information scale
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
---|---|
Active Comparator: Group A patients of this group will receive 5 mg of Melatonin 12 hours and 5 mg 2 hours prior to surgery |
Drug: Melatonin 5 MG Sublingual Tablet
Melatonin 5 mg 12 hours and 2 hours prior to surgery
|
Active Comparator: Group B patients of this group will receive 1 mg/kg of Hydroxizin 12 hours and 1 mg/ kg 2 hours prior to surgery |
Drug: Hydroxyzine
Hydroxyzine 1mg/kg 12 hours and 2 hours prior to surgery
|
Outcome Measures
Primary Outcome Measures
- preoperative anxiety [1 hour before surgery]
preoperative anxiety scale
Eligibility Criteria
Criteria
Inclusion Criteria:
- All adult patients scheduled for hip fracture surgery
Exclusion Criteria:
- Patients with contraindications for hydroxizine or Melatonin Patients with severe cognitive impairement
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- Mongi Slim Hospital
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- Melatonin versus Hydroxizin