Prognosis of Elderly Patients With Acute Poisoning.

Sponsor
Sohag University (Other)
Overall Status
Not yet recruiting
CT.gov ID
NCT05185570
Collaborator
(none)
20
9

Study Details

Study Description

Brief Summary

Acute poisoning is a major public health problem all over the world, it causes significant mortality and morbidity. It primarily involves younger populations, with less than 3% of the affected cases being in people aged 60 years or older in most studies. More than half of the intoxication events in the elderly over 65 years old were accidental.

Condition or Disease Intervention/Treatment Phase

    Detailed Description

    The elderly are different from younger adults in many aspects. There are age related physiological changes. They have a higher incidence of comorbidities and use of many medications for chronic conditions, both of which make the elderly more susceptible to acute poisoning and its related consequences.

    Although the elderly form a relatively small proportion of those admitted to hospital for acute self-poisoning, the poisoning in them is often more serious, complications are more frequent and a fatal outcome is more common.

    The presence of multiple physical, social, and psychiatric problems, with possible difficulties in the diagnosis of poisoning make the management of the elderly more complicated than that of younger poisoned patients. There are three main difficulties in diagnosing acute poisoning in the elderly. At first, it may not be easily obvious that the patient has taken an overdose. Secondly, the presence of pre-existing diseases may obscure the clinical picture and finally, the drug may cause physical signs that similar to common problems of old age.

    Study Design

    Study Type:
    Observational
    Anticipated Enrollment :
    20 participants
    Observational Model:
    Case-Only
    Time Perspective:
    Prospective
    Official Title:
    Evaluation of the Risk Factors Influencing the Prognosis of Elderly Patients With Acute Poisoning.
    Anticipated Study Start Date :
    Jan 1, 2022
    Anticipated Primary Completion Date :
    Jun 1, 2022
    Anticipated Study Completion Date :
    Oct 1, 2022

    Outcome Measures

    Primary Outcome Measures

    1. Change in Acute physiology and chronic health evaluation II score (APACHE II) in cases of elderly patients with acute poisoning. [24 hours after admission to intensive care unit (ICU).]

      "Acute Physiology And Chronic Health Evaluation II(APACHE II) " is a severity-of-disease classification system. one of several ICU scoring systems. It is applied within 24 hours of admission of a patient to an intensive care unit (ICU): an integer score from 0 to 71 is computed based on several measurements; higher scores correspond to more severe disease and a higher risk of death.

    2. Change in Poisoning Severity Score (PSS) in cases of elderly patients with acute poisoning. [24 hours after admission to intensive care unit (ICU).]

      "Poisoning Severity Score (PSS)" is a standardized scale for grading the severity of poisoning allows qualitative evaluation of. morbidity caused by poisoning, better identification of real risks and comparability of data.

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    60 Years and Older
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    No
    Inclusion Criteria:

    all patients more than 60 years will be included.

    Exclusion Criteria:

    younger than 60 years.

    Contacts and Locations

    Locations

    No locations specified.

    Sponsors and Collaborators

    • Sohag University

    Investigators

    None specified.

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    Abeer hussien Mohamed, Teaching assistant in Forensic Medicine &Clinical Toxicology Department Faculty of Medicine, Sohag University
    ClinicalTrials.gov Identifier:
    NCT05185570
    Other Study ID Numbers:
    • Soh-Med-21-12-01
    First Posted:
    Jan 11, 2022
    Last Update Posted:
    Jan 19, 2022
    Last Verified:
    Dec 1, 2021
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Additional relevant MeSH terms:

    Study Results

    No Results Posted as of Jan 19, 2022