The Prognostic Value of Serum Biomarkers in Osteosarcoma
Study Details
Study Description
Brief Summary
Observational retrospective cohort study using laboratory data of blood tests prior to surgical and chemotherapy treatment and other histologic, clinical, and instrumental data related to patient history from digitized medical records and analysis of the same as predictors of outcomes.
Condition or Disease | Intervention/Treatment | Phase |
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Study Design
Outcome Measures
Primary Outcome Measures
- Evaluation of 5-year survival [5 years]
Evaluation of 5-year survival in relation to histologic, laboratory, clinical, and instrumental prognostic factors
Secondary Outcome Measures
- Evaluation of the rate of local recurrence [5 years]
Evaluation of the rate of local recurrence and distant metastasis in relation to histological, laboratory, clinical, and instrumental prognostic factors.
Eligibility Criteria
Criteria
Inclusion Criteria:
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Osteosarcoma diagnosed at the Pathological Anatomy of the Rizzoli Orthopaedic Institute in Bologna;
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Minimum 2-year follow-up period;
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Medical records, complete blood work and instrumental examinations, regular follow-up;
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Patients with age ≥ 2 years;
Exclusion Criteria:
- Patients with osteosarcoma who have received medical treatment (surgery, radiotherapy or chemotherapy) in other hospitals prior to admission to our Institute
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
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1 | IRCCS Itituto Ortopedico Rizzoli | Bologna | BO | Italy | 40136 |
Sponsors and Collaborators
- Istituto Ortopedico Rizzoli
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- ProOsteo