Radiation Therapy With or Without Androgen-Deprivation Therapy in Treating Patients With Prostate Cancer
Study Details
Study Description
Brief Summary
RATIONALE: Radiation therapy uses high-energy x-rays and other types of radiation to kill tumor cells and shrink tumors. Androgens can cause the growth of prostate cancer cells. Androgen-deprivation therapy may lessen the amount of androgens made by the body. It is not yet known whether radiation therapy is more effective with or without androgen-deprivation therapy in treating patients with prostate cancer.
PURPOSE: This randomized phase III trial is studying radiation therapy to see how well it works compared with radiation therapy given together with androgen-deprivation therapy in treating patients with prostate cancer.
Condition or Disease | Intervention/Treatment | Phase |
---|---|---|
|
Phase 3 |
Detailed Description
OBJECTIVES:
Primary
- Demonstrate an overall survival (OS) advantage in patients with intermediate-risk prostate cancer treated with dose-escalated radiotherapy (RT) with versus without short-term androgen-deprivation therapy (ADT).
Secondary
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Determine whether the addition of ADT to dose-escalated RT versus RT alone improves clinical failures, biochemical failure by the "nadir +2", freedom from failure, rate of salvage ADT, and prostate cancer-specific mortality in these patients.
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Estimate the magnitude of benefit of ADT with respect to OS in patients treated with different RT modalities (i.e., external-beam radiation therapy alone vs low-dose rate brachytherapy boost vs high-dose rate brachytherapy boost).
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Compare acute and late treatment adverse events of these regimens and correlate these events with the presence or absence of pre-existing comorbidity as documented by the Adult Comorbidity Evaluation 27 assessment.
OUTLINE: This is a multicenter, dose-escalation study of radiotherapy. Patients are stratified according to number of risk factors (1 vs 2-3), comorbidity (ACE-27 grade ≥ 2 vs < 2), and radiotherapy (RT) modality (dose-escalated external-beam RT [EBRT] vs EBRT and low-dose rate brachytherapy boost vs EBRT and high-dose rate brachytherapy boost). Patients are randomized to 1 of 2 treatment arms.
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Arm I: Patients undergo EBRT* once daily on days 1-5 for about 9 weeks (44 treatments). Some patients instead receive EBRT with high-dose rate or low-dose rate brachytherapy implant on days 1-5 for about 5 weeks (25 treatments). NOTE: *Type of RT is at discretion of treating physician and may include either 3D-conformal RT or intensity-modulated RT.
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Arm II: Patients receive androgen-deprivation therapy comprising luteinizing-hormone releasing-hormone (LHRH) agonist (leuprolide, goserelin, buserelin, or triptorelin) subcutaneously or as an injection every 1 to 3 months AND an oral antiandrogen therapy (flutamide 3 times daily or bicalutamide once daily) for 6 months. Beginning 8 weeks after the first LHRH injection, patients undergo radiotherapy as in arm I.
After completion of study therapy, patients are followed up periodically.
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
---|---|
Active Comparator: Arm I Patients undergo external-beam radiation therapy (EBRT) once daily on days 1-5. Some patients instead receive EBRT with high-dose rate or low-dose rate brachytherapy implant. |
Radiation: 3-dimensional conformal radiation therapy
Given as external-beam radiation therapy
Radiation: intensity-modulated radiation therapy
Given as external-beam radiation therapy
|
Experimental: Arm II Patients receive androgen-deprivation therapy comprising luteinizing-hormone releasing-hormone (LHRH) agonist (leuprolide, goserelin, buserelin, or triptorelin) subcutaneously or as an injection every 1 to 3 months AND an oral antiandrogen therapy (flutamide 3 times daily or bicalutamide once daily) for 6 months. Beginning 8 weeks after the first LHRH injection, patients undergo radiotherapy as in arm I. |
Drug: bicalutamide
Given orally
Drug: buserelin
Given subcutaneously or as an injection
Drug: flutamide
Given orally
Drug: goserelin acetate
Given subcutaneously or as an injection
Drug: leuprolide acetate
Given subcutaneously or as an injection
Drug: triptorelin
Given subcutaneously or as an injection
Radiation: 3-dimensional conformal radiation therapy
Given as external-beam radiation therapy
Radiation: intensity-modulated radiation therapy
Given as external-beam radiation therapy
|
Outcome Measures
Primary Outcome Measures
- Overall survival (OS) [From the date of randomization to the date of death due to any cause.]
Secondary Outcome Measures
- Biochemical failure according to the Phoenix (nadir + 2) definition [From the date of randomization to the date of first documented rise in PSA of 2 ng/ml above the post treatment nadir value.]
- Local recurrence [From the date of randomization to the date of first palpable progression or pathologic confirmation of local progression or to the date of first biochemical failure (nadir +2ng/ml) once the possibility of distant metastasis is ruled out.]
- Regional recurrence [From the date of randomization to the date of first documented progression in pelvic lymph nodes or the date of first documented biochemical failure (BCF) if the CT of the pelvis was prompted by a BCF.]
- Distant metastasis [From the date of randomization to the date of first documented metastatic disease by any measure or to the date of first documented biochemical failure if diagnostic imaging is prompted by BCF.]
- Prostate cancer-specific mortality [From the date of randomization to the date of death due to prostate cancer/complication of treatment.]
- Non-prostate cancer-specific mortality [From the date of randomization to the date of death without the evidence of prostate cancer/complication of treatment.]
- Rate of salvage androgen-deprivation therapy [From the end of treatment to the date of first administration of ADT.]
- Rates of OS for patients treated with the 3 different radiotherapy modalities in each arm [From the date of randomization to the date of death due to any cause.]
- Incidence of "acute" adverse events as assessed by NCI Common Toxicity Criteria for Adverse Effects (CTCAE) v. 4.0 [From the start of radiation therapy (RT) to first occurrence of worse severity of adverse event within 30 days after the completion of RT.]
- Time to "late" grade 3+ adverse events as assessed by NCI CTCAE v. 4.0 [From the date of completion of RT to the date of first grade 3 or above adverse event occurring 30 days after the completion of RT.]
- Freedom from Failure [From date of randomization to the date of first event of biochemical failure or local recurrence or regional reccurrence or distant metastasis.]
- Comparison of prostate cancer-specific health related quality of life (HRQOL) change as measured by EPIC [From date of randomization to the following times: last week of RT, 6 months, 1 year and 5 years post RT.]
- Comparison of fatigue status as measured by the Patient Reported Outcome Measurement Information System (PROMIS) fatigue domain [From date of randomization to the following times: last week of RT, 6 months, 1 year and 5 years post RT.]
- Assessment and comparison of Quality Adjusted Life Years (QALYs) [From date of randomization to the following times: last week of RT, 6 months, 1 year and 5 years post RT.]
- Correlation between the fatigue PROMIS score change and plasma cytokine change [From date of randomization to 3 weeks from start of RT.]
Eligibility Criteria
Criteria
DISEASE CHARACTERISTICS:
-
Histologically confirmed adenocarcinoma of the prostate diagnosed within the past 180 days and at intermediate-risk for recurrence by meeting 1 or more of the following criteria:
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Gleason score = 7
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Prostate Specific Antigen (PSA) > 10 and ≤ 20 ng/mL
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Baseline serum PSA value performed within 60 days with an FDA-approved assay (e.g., Abbott, Hybritech)
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Baseline PSA must not be obtained during any of the following time frames:10-day period after prostate biopsy, after initiation of androgen-deprivation therapy, or within the past 30 days after discontinuation of finasteride (90 days for dutasteride)
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Clinical stage T2b or T2c disease
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Patients previously diagnosed with low-risk (Gleason score < 6, clinical stage < T2a, and PSA < 10 ng/mL) prostate cancer undergoing active surveillance who are re-biopsied and found to have intermediate-risk disease according to the protocol criteria are eligible for enrollment within 6 months of the repeat biopsy procedure
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Patients with Gleason Score ≥ 8, PSA > 20 ng/mL, OR clinical stage ≥ T3 are ineligible for this trial
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If findings of extracapsular extension or seminal vesicle invasion are noted on prostate MRI, this study, if used, will not render patients ineligible for accrual to this protocol
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Primary tumor staging for eligibility purposes is to be based on palpable or core biopsy evidence only with respect to extracapsular extension or seminal vesicle involvement
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No patients with all 3 intermediate-risk factors who also have ≥ 50% of the number of their biopsy cores positive for cancer
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The percentage of biopsy cores involved will only be considered with respect to eligibility for those patients with all 3 of the above risk factors (i.e., patients with one or two of the above risk factors are eligible irrespective of the percentage of biopsy cores involved)
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Clinically negative lymph nodes as established by imaging (pelvic and/or abdominal CT scan or MRI), nodal sampling, or dissection within the past 60 days (required for patients with 2-3 risk factors)
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Abdominal imaging not required for a single intermediate-risk factor (these studies may be obtained at the discretion of the treating physician)
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Lymph nodes that are equivocal or questionable by imaging allowed without biopsy if nodes ≤ 1.5 cm
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Any node > 1.5 cm on imaging requires a negative biopsy
-
No evidence of bone metastases on bone scan within the past 60 days
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Bone scan not required for patients with a single intermediate-risk factor (scan may be obtained at the discretion of the treating physician)
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Equivocal bone scan findings allowed if plain film x-rays negative for metastasis
PATIENT CHARACTERISTICS:
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Zubrod performance status 0-1
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Absolute neutrophil count (ANC) ≥ 1,800/mm^3*
-
Platelet count ≥ 100,000/mm^3*
-
Hemoglobin ≥ 8.0 g/dL (transfusion or other intervention to achieve level allowed)*
-
NOTE: *For patients undergoing brachytherapy only.
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Fertile patients must use effective contraception during and for the 3 months after cessation of protocol treatment
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No invasive malignancy or hematological malignancy (e.g., leukemia, lymphoma, myeloma) within the past 5 years except adequately treated non-melanomatous skin cancer
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Prior diagnoses of carcinoma in situ allowed
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No severe or active co-morbidity with any of the following:
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Unstable angina and/or congestive heart failure requiring hospitalization within the past 6 months
-
Transmural myocardial infarction within the past 6 months
-
Acute bacterial or fungal infection requiring intravenous antibiotics
-
Chronic obstructive pulmonary disease exacerbation or other respiratory illness requiring hospitalization or precluding study therapy, within the past 30 days
-
Hepatic insufficiency resulting in clinical jaundice and/or coagulation defects
-
Laboratory tests for liver function and coagulation parameters not required for entry into this protocol
-
AIDS based upon current Centers for Disease Control (CDC) definition
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HIV testing not required for entry into this protocol
-
HIV-seropositive patients who do not meet criteria for diagnosis of AIDS allowed
PRIOR CONCURRENT THERAPY:
-
See Disease Characteristics
-
No prior radical surgery (prostatectomy), high-intensity focused ultrasound, or cryosurgery for prostate cancer
-
No prior hormonal therapy, such as LHRH agonists (e.g., goserelin, leuprolide), antiandrogens (e.g., flutamide, bicalutamide), estrogens (e.g., DES), or bilateral orchiectomy
-
No finasteride within past 30 days (90 days for dutasteride)
-
No prior or concurrent cytotoxic chemotherapy for prostate cancer
-
Prior chemotherapy for a different cancer allowed
-
No prior radiotherapy (RT), including brachytherapy, to the region of the study cancer that would result in overlap of RT fields
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Patients undergoing brachytherapy must have transrectal ultrasound confirmation of prostate volume < 60 cc, American Urological Association (AUA) score ≤ 15 within the past 60 days of registration, and no history of prior transurethral resection of the prostate (TURP)
-
TURP allowed for patients who receive external-beam radiation therapy only
Contacts and Locations
Locations
Site | City | State | Country | Postal Code | |
---|---|---|---|---|---|
1 | University of Alabama at Birmingham Cancer Center | Birmingham | Alabama | United States | 35233 |
2 | Fairbanks Memorial Hospital | Fairbanks | Alaska | United States | 99701 |
3 | Arizona Center for Cancer Care-Peoria | Peoria | Arizona | United States | 85381 |
4 | Saint Joseph's Hospital and Medical Center | Phoenix | Arizona | United States | 85013 |
5 | 21st Century Oncology-Scottsdale | Scottsdale | Arizona | United States | 85251 |
6 | Mayo Clinic in Arizona | Scottsdale | Arizona | United States | 85259 |
7 | Arizona Oncology Services Foundation | Scottsdale | Arizona | United States | 85260 |
8 | Arizona Oncology Associates-West Orange Grove | Tucson | Arizona | United States | 85704 |
9 | Mercy Cancer Center-Hot Springs | Hot Springs | Arkansas | United States | 71913 |
10 | Sutter Cancer Centers Radiation Oncology Services-Auburn | Auburn | California | United States | 95603 |
11 | Alta Bates Summit Medical Center-Herrick Campus | Berkeley | California | United States | 94704 |
12 | Providence Saint Joseph Medical Center/Disney Family Cancer Center | Burbank | California | United States | 91505 |
13 | Sutter Cancer Centers Radiation Oncology Services-Cameron Park | Cameron Park | California | United States | 95682 |
14 | Mercy San Juan Medical Center | Carmichael | California | United States | 95608 |
15 | Enloe Medical Center | Chico | California | United States | 95926 |
16 | 21st Century Oncology - El Segundo | El Segundo | California | United States | 90245 |
17 | Fresno Cancer Center | Fresno | California | United States | 93720 |
18 | Saint Agnes Medical Center | Fresno | California | United States | 93720 |
19 | Marin General Hospital | Greenbrae | California | United States | 94904 |
20 | Veterans Administration Long Beach Medical Center | Long Beach | California | United States | 90822 |
21 | Los Angeles County-USC Medical Center | Los Angeles | California | United States | 90033 |
22 | USC / Norris Comprehensive Cancer Center | Los Angeles | California | United States | 90033 |
23 | Memorial Medical Center | Modesto | California | United States | 95355 |
24 | Kaiser Permanente Oakland-Broadway | Oakland | California | United States | 94611 |
25 | Kaiser Permanente-Oakland | Oakland | California | United States | 94611 |
26 | Desert Regional Medical Center | Palm Springs | California | United States | 92262 |
27 | Stanford Cancer Institute | Palo Alto | California | United States | 94304 |
28 | Feather River Cancer Center | Paradise | California | United States | 95969 |
29 | Pomona Valley Hospital Medical Center | Pomona | California | United States | 91767 |
30 | Kaiser Permanente-Rancho Cordova Cancer Center | Rancho Cordova | California | United States | 95670 |
31 | Kaiser Permanente-Redwood City | Redwood City | California | United States | 94063 |
32 | Kaiser Permanente-Richmond | Richmond | California | United States | 94801 |
33 | Rohnert Park Cancer Center | Rohnert Park | California | United States | 94928 |
34 | Kaiser Permanente-Roseville | Roseville | California | United States | 95661 |
35 | Sutter Cancer Centers Radiation Oncology Services-Roseville | Roseville | California | United States | 95661 |
36 | The Permanente Medical Group-Roseville Radiation Oncology | Roseville | California | United States | 95678 |
37 | Sutter General Hospital | Sacramento | California | United States | 95816 |
38 | University of California Davis Comprehensive Cancer Center | Sacramento | California | United States | 95817 |
39 | Mercy General Hospital Radiation Oncology Center | Sacramento | California | United States | 95819 |
40 | Kaiser Permanente-South Sacramento | Sacramento | California | United States | 95823 |
41 | South Sacramento Cancer Center | Sacramento | California | United States | 95823 |
42 | Kaiser Permanente - Sacramento | Sacramento | California | United States | 95825 |
43 | University of California San Diego | San Diego | California | United States | 92103 |
44 | Kaiser Permanente-San Francisco | San Francisco | California | United States | 94115 |
45 | UCSF Medical Center-Mount Zion | San Francisco | California | United States | 94115 |
46 | California Pacific Medical Center-Pacific Campus | San Francisco | California | United States | 94118 |
47 | Kaiser Permanente-Santa Teresa-San Jose | San Jose | California | United States | 95119 |
48 | Kaiser Permanente San Leandro | San Leandro | California | United States | 94577 |
49 | Kaiser Permanente-San Rafael | San Rafael | California | United States | 94903 |
50 | Kaiser Permanente Medical Center - Santa Clara | Santa Clara | California | United States | 95051 |
51 | Kaiser Permanente-Santa Rosa | Santa Rosa | California | United States | 95403 |
52 | Kaiser Permanente Cancer Treatment Center | South San Francisco | California | United States | 94080 |
53 | Kaiser Permanente-South San Francisco | South San Francisco | California | United States | 94080 |
54 | Kaiser Permanente-Stockton | Stockton | California | United States | 95210 |
55 | David Grant United States Air Force Medical Center | Travis Air Force Base | California | United States | 94535-1800 |
56 | Tahoe Forest Cancer Center | Truckee | California | United States | 96161 |
57 | Sutter Cancer Centers Radiation Oncology Services-Vacaville | Vacaville | California | United States | 95687 |
58 | Sutter Solano Medical Center/Cancer Center | Vallejo | California | United States | 94589 |
59 | Kaiser Permanente-Walnut Creek | Walnut Creek | California | United States | 94596 |
60 | Rocky Mountain Cancer Centers-Aurora | Aurora | Colorado | United States | 80012 |
61 | University of Colorado Cancer Center - Anschutz Cancer Pavilion | Aurora | Colorado | United States | 80045 |
62 | The Urology Center of Colorado | Denver | Colorado | United States | 80211 |
63 | The Shaw Regional Cancer Center | Edwards | Colorado | United States | 81632 |
64 | Poudre Valley Hospital | Fort Collins | Colorado | United States | 80524 |
65 | Saint Mary's Hospital and Regional Medical Center | Grand Junction | Colorado | United States | 81502 |
66 | Rocky Mountain Cancer Centers-Littleton | Littleton | Colorado | United States | 80120 |
67 | Hartford Hospital | Hartford | Connecticut | United States | 06102 |
68 | Saint Francis Hospital and Medical Center | Hartford | Connecticut | United States | 06105 |
69 | Midstate Medical Center | Meriden | Connecticut | United States | 06451 |
70 | The Hospital of Central Connecticut | New Britain | Connecticut | United States | 06050 |
71 | Yale-New Haven Hospital Saint Raphael Campus | New Haven | Connecticut | United States | 06511 |
72 | Helen F Graham Cancer Center | Newark | Delaware | United States | 19713 |
73 | Christiana Care Health System-Christiana Hospital | Newark | Delaware | United States | 19718 |
74 | University of Miami Sylvester Comprehensive Cancer Center at Deerfield Beach | Deerfield Beach | Florida | United States | 33442 |
75 | Broward Health Medical Center | Fort Lauderdale | Florida | United States | 33316 |
76 | Mayo Clinic in Florida | Jacksonville | Florida | United States | 32224-9980 |
77 | Florida Hospital Kissimmee | Kissimmee | Florida | United States | 34744 |
78 | Lakeland Regional Cancer Center | Lakeland | Florida | United States | 33805 |
79 | The Watson Clinic | Lakeland | Florida | United States | 33805 |
80 | Jackson Memorial Hospital-Holtz Children's Hospital | Miami | Florida | United States | 33136 |
81 | University of Miami Miller School of Medicine-Sylvester Cancer Center | Miami | Florida | United States | 33136 |
82 | South Miami Hospital | Miami | Florida | United States | 33143 |
83 | Florida Hospital Orlando | Orlando | Florida | United States | 32803 |
84 | Bay Medical Center | Panama City | Florida | United States | 32401 |
85 | James A. Haley Veterans Affairs Hospital | Tampa | Florida | United States | 33612 |
86 | Grady Health System | Atlanta | Georgia | United States | 30303 |
87 | Piedmont Hospital | Atlanta | Georgia | United States | 30309 |
88 | Emory University/Winship Cancer Institute | Atlanta | Georgia | United States | 30322 |
89 | Northside Hospital | Atlanta | Georgia | United States | 30342 |
90 | John B Amos Cancer Center | Columbus | Georgia | United States | 31904 |
91 | Northside Hospital-Forsyth | Cumming | Georgia | United States | 30041 |
92 | Atlanta VA Medical Center | Decatur | Georgia | United States | 30033 |
93 | Piedmont Fayette Hospital | Fayetteville | Georgia | United States | 30214 |
94 | Northeast Georgia Medical Center | Gainesville | Georgia | United States | 30501 |
95 | Memorial University Medical Center | Savannah | Georgia | United States | 31404 |
96 | Lewis Cancer and Research Pavilion at Saint Joseph's/Candler | Savannah | Georgia | United States | 31405 |
97 | Queen's Medical Center | Honolulu | Hawaii | United States | 96813 |
98 | University of Hawaii Cancer Center | Honolulu | Hawaii | United States | 96813 |
99 | The Cancer Center of Hawaii-Liliha | Honolulu | Hawaii | United States | 96817 |
100 | Saint Alphonsus Cancer Care Center-Boise | Boise | Idaho | United States | 83706 |
101 | Idaho Urologic Institute-Meridian | Meridian | Idaho | United States | 83642 |
102 | Kootenai Cancer Center | Post Falls | Idaho | United States | 83854 |
103 | Saint Anthony's Health | Alton | Illinois | United States | 62002 |
104 | Memorial Hospital of Carbondale | Carbondale | Illinois | United States | 62902 |
105 | Northwestern University | Chicago | Illinois | United States | 60611 |
106 | John H Stroger Jr Hospital of Cook County | Chicago | Illinois | United States | 60612-3785 |
107 | University of Chicago Comprehensive Cancer Center | Chicago | Illinois | United States | 60637 |
108 | Advocate Illinois Masonic Medical Center | Chicago | Illinois | United States | 60657 |
109 | Decatur Memorial Hospital | Decatur | Illinois | United States | 62526 |
110 | Crossroads Cancer Center | Effingham | Illinois | United States | 62401 |
111 | Hines Veterans Administration Hospital | Hines | Illinois | United States | 60141 |
112 | Loyola University Medical Center | Maywood | Illinois | United States | 60153 |
113 | Pekin Cancer Treatment Center | Pekin | Illinois | United States | 61554 |
114 | OSF Saint Francis Medical Center Radiation Oncology Service at the Central Illinois Comprehensive CC | Peoria | Illinois | United States | 61615-7827 |
115 | OSF Saint Francis Medical Center | Peoria | Illinois | United States | 61637 |
116 | SwedishAmerican Regional Cancer Center/ACT | Rockford | Illinois | United States | 61114 |
117 | Saint John's Hospital | Springfield | Illinois | United States | 62702 |
118 | Memorial Medical Center | Springfield | Illinois | United States | 62781-0001 |
119 | Memorial and Saint Elizabeth's Health Care Services LLP | Swansea | Illinois | United States | 62226 |
120 | Saint Vincent Anderson Regional Hospital/Cancer Center | Anderson | Indiana | United States | 46016 |
121 | IU Health West Hospital | Avon | Indiana | United States | 46123 |
122 | IU Health Bloomington | Bloomington | Indiana | United States | 47403 |
123 | Radiation Oncology Associates PC | Fort Wayne | Indiana | United States | 46804 |
124 | Parkview Hospital Randallia | Fort Wayne | Indiana | United States | 46805 |
125 | IU Health Goshen Center for Cancer Care | Goshen | Indiana | United States | 46526 |
126 | Indiana University/Melvin and Bren Simon Cancer Center | Indianapolis | Indiana | United States | 46202 |
127 | IU Health Methodist Hospital | Indianapolis | Indiana | United States | 46202 |
128 | Richard L. Roudebush Veterans Affairs Medical Center | Indianapolis | Indiana | United States | 46202 |
129 | IU Health Central Indiana Cancer Centers-East | Indianapolis | Indiana | United States | 46219 |
130 | McFarland Clinic PC-William R Bliss Cancer Center | Ames | Iowa | United States | 50010 |
131 | Medical Oncology and Hematology Associates-West Des Moines | Clive | Iowa | United States | 50325 |
132 | Iowa Methodist Medical Center | Des Moines | Iowa | United States | 50309 |
133 | Iowa Oncology Research Association CCOP | Des Moines | Iowa | United States | 50309 |
134 | Medical Oncology and Hematology Associates-Des Moines | Des Moines | Iowa | United States | 50309 |
135 | Medical Oncology and Hematology Associates-Laurel | Des Moines | Iowa | United States | 50314 |
136 | Mercy Medical Center - Des Moines | Des Moines | Iowa | United States | 50314 |
137 | Iowa Lutheran Hospital | Des Moines | Iowa | United States | 50316 |
138 | Finley Hospital | Dubuque | Iowa | United States | 52001 |
139 | Cancer Center of Kansas - Dodge City | Dodge City | Kansas | United States | 67801 |
140 | Cancer Center of Kansas - El Dorado | El Dorado | Kansas | United States | 67042 |
141 | Lawrence Memorial Hospital | Lawrence | Kansas | United States | 66044 |
142 | Kansas City Cancer Centers-Southwest | Overland Park | Kansas | United States | 66210 |
143 | Cancer Center of Kansas - Wellington | Wellington | Kansas | United States | 67152 |
144 | Associates In Womens Health | Wichita | Kansas | United States | 67208 |
145 | Cancer Center of Kansas-Wichita Medical Arts Tower | Wichita | Kansas | United States | 67208 |
146 | Cancer Center of Kansas - Main Office | Wichita | Kansas | United States | 67214 |
147 | Via Christi Regional Medical Center | Wichita | Kansas | United States | 67214 |
148 | Wesley Medical Center | Wichita | Kansas | United States | 67214 |
149 | Wichita CCOP | Wichita | Kansas | United States | 67214 |
150 | Cancer Center of Kansas - Winfield | Winfield | Kansas | United States | 67156 |
151 | Baptist Health Lexington | Lexington | Kentucky | United States | 40503 |
152 | University of Kentucky/Markey Cancer Center | Lexington | Kentucky | United States | 40536 |
153 | The James Graham Brown Cancer Center at University of Louisville | Louisville | Kentucky | United States | 40202 |
154 | Owensboro Health Mitchell Memorial Cancer Center | Owensboro | Kentucky | United States | 42303 |
155 | Mary Bird Perkins Cancer Center | Baton Rouge | Louisiana | United States | 70809 |
156 | Tulane University Health Sciences Center | New Orleans | Louisiana | United States | 70112 |
157 | Ochsner Medical Center Jefferson | New Orleans | Louisiana | United States | 70121 |
158 | Central Maine Medical Center | Lewiston | Maine | United States | 04240 |
159 | Maine Medical Center- Scarborough Campus | Scarborough | Maine | United States | 04074 |
160 | Anne Arundel Medical Center | Annapolis | Maryland | United States | 21401 |
161 | University of Maryland/Greenebaum Cancer Center | Baltimore | Maryland | United States | 21201 |
162 | Greater Baltimore Medical Center | Baltimore | Maryland | United States | 21204 |
163 | Saint Agnes Hospital | Baltimore | Maryland | United States | 21229 |
164 | Upper Chesapeake Medical Center | Bel Air | Maryland | United States | 21015 |
165 | Walter Reed National Military Medical Center | Bethesda | Maryland | United States | 20889-5600 |
166 | Central Maryland Radiation Oncology in Howard County | Columbia | Maryland | United States | 21044 |
167 | Tate Cancer Center | Glen Burnie | Maryland | United States | 21061 |
168 | Holy Cross Hospital | Silver Spring | Maryland | United States | 20910 |
169 | Massachusetts General Hospital Cancer Center | Boston | Massachusetts | United States | 02114 |
170 | Boston Medical Center | Boston | Massachusetts | United States | 02118 |
171 | Mass General/North Shore Cancer Center | Danvers | Massachusetts | United States | 01923 |
172 | Saint Anne's Hospital | Fall River | Massachusetts | United States | 02721 |
173 | Cape Cod Hospital | Hyannis | Massachusetts | United States | 02601 |
174 | Lowell General Hospital | Lowell | Massachusetts | United States | 01854 |
175 | Berkshire Hematology Oncology PC | Pittsfield | Massachusetts | United States | 01201 |
176 | Beth Israel Deaconess Hospital-Plymouth | Plymouth | Massachusetts | United States | 02360 |
177 | D'Amour Center for Cancer Care | Springfield | Massachusetts | United States | 01107 |
178 | Baystate Medical Center | Springfield | Massachusetts | United States | 01199 |
179 | Saint Vincent Hospital/Reliant Medical Group | Worcester | Massachusetts | United States | 01608 |
180 | Bixby Medical Center | Adrian | Michigan | United States | 49221 |
181 | Veteran's Administration Medical Center - Ann Arbor | Ann Arbor | Michigan | United States | 48105 |
182 | Saint Joseph Mercy Hospital | Ann Arbor | Michigan | United States | 48106-0995 |
183 | University of Michigan Comprehensive Cancer Center | Ann Arbor | Michigan | United States | 48109 |
184 | Bronson Battle Creek | Battle Creek | Michigan | United States | 49017 |
185 | McLaren-Bay Region | Bay City | Michigan | United States | 48708 |
186 | Henry Ford Macomb Hospital | Clinton Township | Michigan | United States | 48038 |
187 | Huron Valley-Sinai Hospital | Commerce | Michigan | United States | 48382 |
188 | Henry Ford Hospital | Detroit | Michigan | United States | 48202 |
189 | Saint John Hospital and Medical Center | Detroit | Michigan | United States | 48236 |
190 | Green Bay Oncology - Escanaba | Escanaba | Michigan | United States | 49431 |
191 | 21st Century Oncology-Farmington Hills | Farmington Hills | Michigan | United States | 48334 |
192 | Botsford General Hospital | Farmington | Michigan | United States | 48334 |
193 | Genesys Hurley Cancer Institute | Flint | Michigan | United States | 48503 |
194 | Genesys Regional Medical Center-West Flint Campus | Flint | Michigan | United States | 48532 |
195 | McLaren-Flint | Flint | Michigan | United States | 48532 |
196 | Mercy Health Saint Mary's | Grand Rapids | Michigan | United States | 49503 |
197 | Spectrum Health at Butterworth Campus | Grand Rapids | Michigan | United States | 49503 |
198 | Green Bay Oncology - Iron Mountain | Iron Mountain | Michigan | United States | 49801 |
199 | Borgess Medical Center | Kalamazoo | Michigan | United States | 49001 |
200 | Bronson Methodist Hospital | Kalamazoo | Michigan | United States | 49007 |
201 | West Michigan Cancer Center | Kalamazoo | Michigan | United States | 49007 |
202 | Sparrow Hospital | Lansing | Michigan | United States | 48912 |
203 | Great Lakes Cancer Institute-Lapeer Campus | Lapeer | Michigan | United States | 48446 |
204 | McLaren-Macomb | Mount Clemens | Michigan | United States | 48043 |
205 | McLaren-Central Michigan | Mount Pleasant | Michigan | United States | 48858 |
206 | Mercy Health Mercy Campus | Muskegon | Michigan | United States | 49444 |
207 | McLaren Cancer Institute-Owosso | Owosso | Michigan | United States | 48867 |
208 | Northern Michigan Regional Hospital | Petoskey | Michigan | United States | 49770 |
209 | Saint Joseph Mercy Oakland | Pontiac | Michigan | United States | 48341 |
210 | Saint Joseph Mercy Port Huron | Port Huron | Michigan | United States | 48060 |
211 | Crittenton Hospital | Rochester | Michigan | United States | 48307 |
212 | William Beaumont Hospital-Royal Oak | Royal Oak | Michigan | United States | 48073 |
213 | Saint Mary's of Michigan | Saginaw | Michigan | United States | 48601 |
214 | Downriver Center for Oncology | Trenton | Michigan | United States | 48183 |
215 | 21st Century Oncology-Troy | Troy | Michigan | United States | 48098 |
216 | William Beaumont Hospital - Troy | Troy | Michigan | United States | 48098 |
217 | Saint John Macomb-Oakland Hospital | Warren | Michigan | United States | 48093 |
218 | Henry Ford West Bloomfield Hospital | West Bloomfield | Michigan | United States | 48322 |
219 | Mayo Clinic Health System in Albert Lea | Albert Lea | Minnesota | United States | 56007 |
220 | Sanford Clinic North-Bemidgi | Bemidji | Minnesota | United States | 56601 |
221 | Miller-Dwan Hospital | Duluth | Minnesota | United States | 55805 |
222 | Saint Luke's Hospital of Duluth | Duluth | Minnesota | United States | 55805 |
223 | Fairview-Southdale Hospital | Edina | Minnesota | United States | 55435 |
224 | Mayo Clinic Health Systems-Mankato | Mankato | Minnesota | United States | 56001 |
225 | Mayo Clinic | Rochester | Minnesota | United States | 55905 |
226 | Regions Hospital | Saint Paul | Minnesota | United States | 55101 |
227 | Saint Francis Medical Center | Cape Girardeau | Missouri | United States | 63703 |
228 | Mercy Hospital-Joplin | Joplin | Missouri | United States | 64804 |
229 | Kansas City Cancer Center - South | Kansas City | Missouri | United States | 64131 |
230 | Kansas City Cancer Centers - North | Kansas City | Missouri | United States | 64154 |
231 | Kansas City Cancer Center-Lee's Summit | Lee's Summit | Missouri | United States | 64064 |
232 | Phelps County Regional Medical Center | Rolla | Missouri | United States | 65401 |
233 | Washington University School of Medicine | Saint Louis | Missouri | United States | 63110 |
234 | Siteman Cancer Center-South County | Saint Louis | Missouri | United States | 63129 |
235 | Missouri Baptist Medical Center | Saint Louis | Missouri | United States | 63131 |
236 | Barnes-Jewish West County Hospital | Saint Louis | Missouri | United States | 63141 |
237 | Mercy Hospital Saint Louis | Saint Louis | Missouri | United States | 63141 |
238 | Saint Louis-Cape Girardeau CCOP | Saint Louis | Missouri | United States | 63141 |
239 | Siteman Cancer Center - Saint Peters | Saint Peters | Missouri | United States | 63376 |
240 | Cancer Research for the Ozarks NCORP | Springfield | Missouri | United States | 65804 |
241 | Mercy Hospital Springfield | Springfield | Missouri | United States | 65804 |
242 | CoxHealth South Hospital | Springfield | Missouri | United States | 65807 |
243 | Montana Cancer Consortium CCOP | Billings | Montana | United States | 59101 |
244 | Northern Rockies Radiation Oncology Center | Billings | Montana | United States | 59101 |
245 | Billings Clinic Cancer Center | Billings | Montana | United States | 59107 |
246 | Berdeaux, Donald MD (UIA Investigator) | Great Falls | Montana | United States | 59405 |
247 | Great Falls Clinic | Great Falls | Montana | United States | 59405 |
248 | Saint Elizabeth Regional Medical Center | Lincoln | Nebraska | United States | 68510 |
249 | Missouri Valley Cancer Consortium | Omaha | Nebraska | United States | 68106 |
250 | Nebraska Methodist Hospital | Omaha | Nebraska | United States | 68114 |
251 | Alegent Health Immanuel Medical Center | Omaha | Nebraska | United States | 68122 |
252 | Alegent Health Bergan Mercy Medical Center | Omaha | Nebraska | United States | 68124 |
253 | Alegent Health Lakeside Hospital | Omaha | Nebraska | United States | 68130 |
254 | Creighton University Medical Center | Omaha | Nebraska | United States | 68131 |
255 | University of Nebraska Medical Center | Omaha | Nebraska | United States | 68198 |
256 | Concord Hospital | Concord | New Hampshire | United States | 03301 |
257 | Exeter Hospital | Exeter | New Hampshire | United States | 03833 |
258 | Cheshire Medical Center-Dartmouth-Hitchcock Keene | Keene | New Hampshire | United States | 03431 |
259 | Dartmouth Hitchcock Medical Center | Lebanon | New Hampshire | United States | 03756 |
260 | Elliot Hospital | Manchester | New Hampshire | United States | 03103 |
261 | Ocean Medical Center | Brick | New Jersey | United States | 08724 |
262 | Cooper Hospital University Medical Center | Camden | New Jersey | United States | 08103 |
263 | Veterans Adminstration New Jersey Health Care System | East Orange | New Jersey | United States | 07018-1095 |
264 | CentraState Medical Center | Freehold | New Jersey | United States | 07728 |
265 | Princeton Radiation Oncology Center | Monroe | New Jersey | United States | 08831 |
266 | Fox Chase Cancer Center at Virtua Memorial Hospital of Burlington County | Mount Holly | New Jersey | United States | 08060 |
267 | Jersey Shore Medical Center | Neptune | New Jersey | United States | 07753 |
268 | Rutgers Cancer Institute of New Jersey | New Brunswick | New Jersey | United States | 08903 |
269 | UMDNJ - Robert Wood Johnson University Hospital | New Brunswick | New Jersey | United States | 08903 |
270 | UMDNJ - New Jersey Medical School | Newark | New Jersey | United States | 07103 |
271 | Newark Beth Israel Medical Center | Newark | New Jersey | United States | 07112 |
272 | The Medical Center At Princeton | Princeton | New Jersey | United States | 08540-3298 |
273 | Riverview Medical Center/Booker Cancer Center | Red Bank | New Jersey | United States | 07701 |
274 | Sparta Cancer Treatment Center | Sparta | New Jersey | United States | 07871 |
275 | Community Medical Center | Toms River | New Jersey | United States | 08755 |
276 | MD Anderson Cancer Center at Cooper-Voorhees | Voorhees | New Jersey | United States | 08043 |
277 | Virtua West Jersey Hospital Voorhees | Voorhees | New Jersey | United States | 08043 |
278 | Prostate Cancer Center of New Jersey | West Orange | New Jersey | United States | 07052 |
279 | Lovelace Medical Center-Downtown | Albuquerque | New Mexico | United States | 87102 |
280 | University of New Mexico | Albuquerque | New Mexico | United States | 87102 |
281 | University of New Mexico Cancer Center | Albuquerque | New Mexico | United States | 87106 |
282 | Radiation Oncology Associates | Albuquerque | New Mexico | United States | 87109 |
283 | Memorial Medical Center - Las Cruces | Las Cruces | New Mexico | United States | 88011 |
284 | New York Oncology Hematology PC - Albany | Albany | New York | United States | 12206 |
285 | Saint Peters Hospital-Albany | Albany | New York | United States | 12208 |
286 | Southside Hospital | Bay Shore | New York | United States | 11706 |
287 | Lourdes Hospital | Binghamton | New York | United States | 13905 |
288 | State University of New York Downstate Medical Center | Brooklyn | New York | United States | 11203 |
289 | Veteran Affairs New York Harbor Healthcare System-Brooklyn Campus | Brooklyn | New York | United States | 11209 |
290 | Roswell Park Cancer Institute | Buffalo | New York | United States | 14263 |
291 | Sands Cancer Center | Canandaigua | New York | United States | 14424 |
292 | Mary Imogene Bassett Hospital | Cooperstown | New York | United States | 13326 |
293 | Arnot Ogden Medical Center/Falck Cancer Center | Elmira | New York | United States | 14905 |
294 | North Shore University Hospital | Manhasset | New York | United States | 11030 |
295 | North Shore-LIJ Health System NCORP | Manhasset | New York | United States | 11030 |
296 | Long Island Jewish Medical Center | New Hyde Park | New York | United States | 11040 |
297 | North Shore-LIJ Health System/Center for Advanced Medicine | New Hyde Park | New York | United States | 11040 |
298 | Columbia University Medical Center | New York | New York | United States | 10032 |
299 | Hudson Valley Oncology Associates | Poughkeepsie | New York | United States | 12601 |
300 | Highland Hospital | Rochester | New York | United States | 14620 |
301 | University Radiation Oncology | Rochester | New York | United States | 14626 |
302 | University of Rochester | Rochester | New York | United States | 14642 |
303 | Randolph Hospital | Asheboro | North Carolina | United States | 27203 |
304 | University of North Carolina at Chapel Hill | Chapel Hill | North Carolina | United States | 27599 |
305 | Duke University Medical Center | Durham | North Carolina | United States | 27710 |
306 | Cone Health Cancer Center | Greensboro | North Carolina | United States | 27403 |
307 | The Coleman Radiation Center-Carteret General Hospital | Morehead City | North Carolina | United States | 28557 |
308 | CarolinaEast Health System-Medical Center | New Bern | North Carolina | United States | 28560 |
309 | Duke Cancer Institute Macon Pond | Raleigh | North Carolina | United States | 27607 |
310 | Rex Cancer Center | Raleigh | North Carolina | United States | 27607 |
311 | South Atlantic Radiation Oncology | Supply | North Carolina | United States | 28462 |
312 | Coastal Carolina Radiation Oncology | Wilmington | North Carolina | United States | 28401 |
313 | New Hanover Regional Medical Center/Zimmer Cancer Center | Wilmington | North Carolina | United States | 28401 |
314 | Southeast Cancer Consortium-Upstate NCORP | Winston-Salem | North Carolina | United States | 27104 |
315 | Mid Dakota Clinic | Bismarck | North Dakota | United States | 58501 |
316 | Saint Alexius Medical Center | Bismarck | North Dakota | United States | 58501 |
317 | Sanford Bismarck Medical Center | Bismarck | North Dakota | United States | 58501 |
318 | Sanford Clinic North-Fargo | Fargo | North Dakota | United States | 58122 |
319 | Sanford Medical Center-Fargo | Fargo | North Dakota | United States | 58122 |
320 | Trinity Cancer Care Center | Minot | North Dakota | United States | 58701 |
321 | Summa Akron City Hospital/Cooper Cancer Center | Akron | Ohio | United States | 44304 |
322 | Akron General Medical Center | Akron | Ohio | United States | 44307 |
323 | Summa Barberton Hospital | Barberton | Ohio | United States | 44203 |
324 | UHHS-Chagrin Highlands Medical Center | Beachwood | Ohio | United States | 44122 |
325 | Geaugra Hospital | Chardon | Ohio | United States | 44024 |
326 | Adena Regional Medical Center | Chillicothe | Ohio | United States | 45601 |
327 | University of Cincinnati | Cincinnati | Ohio | United States | 45267 |
328 | Case Western Reserve University | Cleveland | Ohio | United States | 44106 |
329 | Cleveland Clinic Cancer Center/Fairview Hospital | Cleveland | Ohio | United States | 44111 |
330 | Cleveland Clinic Foundation | Cleveland | Ohio | United States | 44195 |
331 | Ohio State University Comprehensive Cancer Center | Columbus | Ohio | United States | 43210 |
332 | Riverside Methodist Hospital | Columbus | Ohio | United States | 43214 |
333 | Columbus CCOP | Columbus | Ohio | United States | 43215 |
334 | Grant Medical Center | Columbus | Ohio | United States | 43215 |
335 | The Mark H Zangmeister Center | Columbus | Ohio | United States | 43219 |
336 | Mount Carmel Health Center West | Columbus | Ohio | United States | 43222 |
337 | Doctors Hospital | Columbus | Ohio | United States | 43228 |
338 | Grady Memorial Hospital | Delaware | Ohio | United States | 43015 |
339 | Mercy Cancer Center-Elyria | Elyria | Ohio | United States | 44035 |
340 | Cleveland Clinic Cancer Center Independence | Independence | Ohio | United States | 44131 |
341 | Marietta Memorial Hospital | Marietta | Ohio | United States | 45750 |
342 | Toledo Clinic Cancer Centers-Maumee | Maumee | Ohio | United States | 43537 |
343 | Hillcrest Hospital Cancer Center | Mayfield Heights | Ohio | United States | 44124 |
344 | Summa Health Center at Lake Medina | Medina | Ohio | United States | 44256 |
345 | Lake University Ireland Cancer Center | Mentor | Ohio | United States | 44060 |
346 | Southwest General Health Center Ireland Cancer Center | Middleburg Heights | Ohio | United States | 44130 |
347 | Licking Memorial Hospital | Newark | Ohio | United States | 43055 |
348 | Saint Charles Hospital | Oregon | Ohio | United States | 43616 |
349 | University Hospitals Parma Medical Center | Parma | Ohio | United States | 44129 |
350 | Southern Ohio Medical Center | Portsmouth | Ohio | United States | 45662 |
351 | Robinson Radiation Oncology | Ravenna | Ohio | United States | 44266 |
352 | Cancer Care Center, Incorporated | Salem | Ohio | United States | 44460 |
353 | Ireland Cancer Center at Firelands Regional Medical Center | Sandusky | Ohio | United States | 44870 |
354 | North Coast Cancer Care | Sandusky | Ohio | United States | 44870 |
355 | Flower Hospital | Sylvania | Ohio | United States | 43560 |
356 | University of Toledo | Toledo | Ohio | United States | 43614 |
357 | Mercy Saint Anne Hospital | Toledo | Ohio | United States | 43623 |
358 | University Pointe | West Chester | Ohio | United States | 45069 |
359 | Saint Ann's Hospital | Westerville | Ohio | United States | 43081 |
360 | UHHS-Westlake Medical Center | Westlake | Ohio | United States | 44145 |
361 | Cancer Treatment Center | Wooster | Ohio | United States | 44691 |
362 | Cleveland Clinic Wooster Specialty Center | Wooster | Ohio | United States | 44691 |
363 | Wright-Patterson Medical Center | Wright-Patterson Air Force Base | Ohio | United States | 45433-5529 |
364 | Genesis HealthCare System | Zanesville | Ohio | United States | 43701 |
365 | University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | United States | 73104 |
366 | Clackamas Radiation Oncology Center | Clackamas | Oregon | United States | 97015 |
367 | Willamette Valley Cancer Center | Eugene | Oregon | United States | 97401 |
368 | Three Rivers Community Hospital | Grants Pass | Oregon | United States | 97527 |
369 | Legacy Mount Hood Medical Center | Gresham | Oregon | United States | 97030 |
370 | Asante Health System | Medford | Oregon | United States | 97504 |
371 | Providence Medford Medical Center | Medford | Oregon | United States | 97504 |
372 | Rogue Valley Medical Center | Medford | Oregon | United States | 97504 |
373 | Providence Milwaukie Hospital | Milwaukie | Oregon | United States | 97222 |
374 | Legacy Good Samaritan Hospital and Medical Center | Portland | Oregon | United States | 97210 |
375 | Providence Portland Medical Center | Portland | Oregon | United States | 97213 |
376 | Western Oncology Research Consortium | Portland | Oregon | United States | 97213 |
377 | Providence Saint Vincent Medical Center | Portland | Oregon | United States | 97225 |
378 | Legacy Meridian Park Hospital | Tualatin | Oregon | United States | 97062 |
379 | Abington Memorial Hospital | Abington | Pennsylvania | United States | 19001 |
380 | Saint Luke's University Hospital-Bethlehem Campus | Bethlehem | Pennsylvania | United States | 18015 |
381 | Bryn Mawr Hospital | Bryn Mawr | Pennsylvania | United States | 19010 |
382 | Geisinger Medical Center | Danville | Pennsylvania | United States | 17822 |
383 | Mercy Fitzgerald Hospital | Darby | Pennsylvania | United States | 19023-1291 |
384 | Delaware County Memorial Hospital | Drexel Hill | Pennsylvania | United States | 19026 |
385 | Northeast Radiation Oncology Center | Dunmore | Pennsylvania | United States | 18512 |
386 | The Regional Cancer Center | Erie | Pennsylvania | United States | 16505 |
387 | Fox Chase Cancer Center Buckingham | Furlong | Pennsylvania | United States | 18925 |
388 | Adams Cancer Center | Gettysburg | Pennsylvania | United States | 17325 |
389 | Cherry Tree Cancer Center | Hanover | Pennsylvania | United States | 17331 |
390 | Penn State Milton S Hershey Medical Center | Hershey | Pennsylvania | United States | 17033-0850 |
391 | Academic Urology Prostate Center | King Of Prussia | Pennsylvania | United States | 19406 |
392 | Saint Mary Medical and Regional Cancer Center | Langhorne | Pennsylvania | United States | 19047 |
393 | Upper Delaware Valley Cancer Center | Milford | Pennsylvania | United States | 18337 |
394 | Paoli Memorial Hospital | Paoli | Pennsylvania | United States | 19301 |
395 | Thomas Jefferson University Hospital | Philadelphia | Pennsylvania | United States | 19107 |
396 | Fox Chase Cancer Center | Philadelphia | Pennsylvania | United States | 19111 |
397 | Temple University Hospital | Philadelphia | Pennsylvania | United States | 19140 |
398 | Albert Einstein Medical Center | Philadelphia | Pennsylvania | United States | 19141 |
399 | VA Pittsburgh Healthcare System | Pittsburgh | Pennsylvania | United States | 15240 |
400 | Reading Hospital | West Reading | Pennsylvania | United States | 19611 |
401 | Lankenau Medical Center | Wynnewood | Pennsylvania | United States | 19096 |
402 | Mainline Health CCOP | Wynnewood | Pennsylvania | United States | 19096 |
403 | WellSpan Health-York Hospital | York | Pennsylvania | United States | 17405 |
404 | AnMed Health Hospital | Anderson | South Carolina | United States | 29621 |
405 | Medical University of South Carolina | Charleston | South Carolina | United States | 29425 |
406 | Greenville Health System Cancer Institute-Faris | Greenville | South Carolina | United States | 29605 |
407 | Greenville Health System Cancer Institute-Eastside | Greenville | South Carolina | United States | 29615 |
408 | Self Regional Healthcare | Greenwood | South Carolina | United States | 29646 |
409 | Greenville Health System Cancer Institute-Greer | Greer | South Carolina | United States | 29650 |
410 | Gibbs Cancer Center-Pelham | Greer | South Carolina | United States | 29651 |
411 | Carolina Regional Cancer Center | Myrtle Beach | South Carolina | United States | 29577 |
412 | Greenville Health System Cancer Institute-Seneca | Seneca | South Carolina | United States | 29672 |
413 | Spartanburg Medical Center | Spartanburg | South Carolina | United States | 29303 |
414 | Greenville Health System Cancer Institute-Spartanburg | Spartanburg | South Carolina | United States | 29307 |
415 | Rapid City Regional Hospital | Rapid City | South Dakota | United States | 57701 |
416 | Wellmont Holston Valley Hospital and Medical Center | Kingsport | Tennessee | United States | 37660 |
417 | Thompson Cancer Survival Center | Knoxville | Tennessee | United States | 37916 |
418 | Blount Memorial Hospital | Maryville | Tennessee | United States | 37804 |
419 | Texas Oncology-Arlington South | Arlington | Texas | United States | 76014 |
420 | Texas Oncology-Austin Midtown | Austin | Texas | United States | 78705 |
421 | Texas Oncology - Central Austin Cancer Center | Austin | Texas | United States | 78731 |
422 | Texas Oncology - South Austin Cancer Center | Austin | Texas | United States | 78745 |
423 | Texas Oncology Bedford | Bedford | Texas | United States | 76022 |
424 | Texas Cancer Center - Medical City Dallas | Dallas | Texas | United States | 75230 |
425 | Texas Oncology Methodist Charlton Cancer Center | Dallas | Texas | United States | 75237 |
426 | UT Southwestern/Simmons Cancer Center-Dallas | Dallas | Texas | United States | 75390 |
427 | Texas Oncology-Denton South | Denton | Texas | United States | 76210 |
428 | Brooke Army Medical Center | Fort Sam Houston | Texas | United States | 78234 |
429 | The Klabzuba Cancer Center | Fort Worth | Texas | United States | 76104 |
430 | University of Texas Medical Branch | Galveston | Texas | United States | 77555-0565 |
431 | Memorial Hermann Memorial City Medical Center | Houston | Texas | United States | 77024 |
432 | M D Anderson Cancer Center | Houston | Texas | United States | 77030 |
433 | UTMB Cancer Center at Victory Lakes | League City | Texas | United States | 77573 |
434 | Texas Oncology - Lewisville | Lewisville | Texas | United States | 75067 |
435 | Texas Oncology-Longview Cancer Center | Longview | Texas | United States | 75601 |
436 | West Texas Cancer Center | Odessa | Texas | United States | 79761 |
437 | Texas Oncology-Seton Williamson | Round Rock | Texas | United States | 78665 |
438 | Texas Oncology - Round Rock Cancer Center | Round Rock | Texas | United States | 78681 |
439 | Texas Cancer Center-Sherman | Sherman | Texas | United States | 75090 |
440 | Texas Oncology Cancer Center Sugar Land | Sugar Land | Texas | United States | 77479 |
441 | Texas Oncology-Wichita Falls Texoma Cancer Center | Wichita Falls | Texas | United States | 76310 |
442 | Sandra L Maxwell Cancer Center | Cedar City | Utah | United States | 84720 |
443 | Intermountain Medical Center | Murray | Utah | United States | 84157 |
444 | McKay-Dee Hospital Center | Ogden | Utah | United States | 84403 |
445 | Utah Valley Regional Medical Center | Provo | Utah | United States | 84604 |
446 | Dixie Medical Center Regional Cancer Center | Saint George | Utah | United States | 84770 |
447 | Utah Cancer Specialists-Salt Lake City | Salt Lake City | Utah | United States | 84106 |
448 | Huntsman Cancer Institute/University of Utah | Salt Lake City | Utah | United States | 84112 |
449 | LDS Hospital | Salt Lake City | Utah | United States | 84143 |
450 | Southwestern Vermont Medical Center | Bennington | Vermont | United States | 05201 |
451 | Rutland Regional Medical Center | Rutland | Vermont | United States | 05701 |
452 | Norris Cotton Cancer Center-North | Saint Johnsbury | Vermont | United States | 05819 |
453 | Inova Alexandria Hospital | Alexandria | Virginia | United States | 22304 |
454 | Danville Regional Medical Center | Danville | Virginia | United States | 24541 |
455 | Augusta Health Cancer Center | Fishersville | Virginia | United States | 22939 |
456 | Sentara Cancer Institute at Sentara CarePlex Hospital | Hampton | Virginia | United States | 23666 |
457 | Sentara Rockingham Memorial Hospital Hahn Cancer Center | Harrisonburg | Virginia | United States | 22801 |
458 | Sentara Hospitals | Norfolk | Virginia | United States | 23507 |
459 | Southwest VA Regional Cancer Center | Norton | Virginia | United States | 24273 |
460 | Naval Medical Center - Portsmouth | Portsmouth | Virginia | United States | 23708-2197 |
461 | Oncology and Hematology Associates of Southwest Virginia | Roanoke | Virginia | United States | 24014 |
462 | Sentara Virginia Beach General Hospital | Virginia Beach | Virginia | United States | 23454 |
463 | PeaceHealth Saint Joseph Medical Center | Bellingham | Washington | United States | 98225 |
464 | Saint Francis Hospital | Federal Way | Washington | United States | 98003 |
465 | Virginia Mason CCOP | Seattle | Washington | United States | 98101 |
466 | Virginia Mason Medical Center | Seattle | Washington | United States | 98101 |
467 | Cancer Care Northwest - Spokane South | Spokane | Washington | United States | 99202 |
468 | Cancer Care Northwest-North Spokane | Spokane | Washington | United States | 99218 |
469 | PeaceHealth Southwest Medical Center | Vancouver | Washington | United States | 98664 |
470 | Compass Oncology Vancouver | Vancouver | Washington | United States | 98684 |
471 | Legacy Salmon Creek Hospital | Vancouver | Washington | United States | 98686 |
472 | Appleton Medical Center | Appleton | Wisconsin | United States | 54911 |
473 | Green Bay Oncology at Saint Vincent Hospital | Green Bay | Wisconsin | United States | 54301-3526 |
474 | Bellin Memorial Hospital | Green Bay | Wisconsin | United States | 54301 |
475 | Saint Vincent Hospital | Green Bay | Wisconsin | United States | 54301 |
476 | Green Bay Oncology Limited at Saint Mary's Hospital | Green Bay | Wisconsin | United States | 54303 |
477 | Saint Mary's Hospital | Green Bay | Wisconsin | United States | 54303 |
478 | Aurora BayCare Medical Center | Green Bay | Wisconsin | United States | 54311-6519 |
479 | UW Cancer Center Johnson Creek | Johnson Creek | Wisconsin | United States | 53038 |
480 | Gundersen Lutheran Medical Center | La Crosse | Wisconsin | United States | 54601 |
481 | Mayo Clinic Health System-Franciscan Healthcare | La Crosse | Wisconsin | United States | 54601 |
482 | Bay Area Medical Center | Marinette | Wisconsin | United States | 54143 |
483 | Vince Lombardi Cancer Clinic-Marinette | Marinette | Wisconsin | United States | 54143 |
484 | Community Memorial Hospital | Menomonee Falls | Wisconsin | United States | 53051 |
485 | Columbia Saint Mary's Hospital - Ozaukee | Mequon | Wisconsin | United States | 53097 |
486 | Columbia Saint Mary's Water Tower Medical Commons | Milwaukee | Wisconsin | United States | 53211 |
487 | Aurora Saint Luke's Medical Center | Milwaukee | Wisconsin | United States | 53215 |
488 | Froedtert and the Medical College of Wisconsin | Milwaukee | Wisconsin | United States | 53226 |
489 | Zablocki Veterans Administration Medical Center | Milwaukee | Wisconsin | United States | 53295 |
490 | Green Bay Oncology - Oconto Falls | Oconto Falls | Wisconsin | United States | 54154 |
491 | Vince Lombardi Cancer Clinic - Oshkosh | Oshkosh | Wisconsin | United States | 54904 |
492 | Wheaton Franciscan Cancer Care - All Saints | Racine | Wisconsin | United States | 53405 |
493 | Door County Cancer Center | Sturgeon Bay | Wisconsin | United States | 54235-1495 |
494 | Green Bay Oncology - Sturgeon Bay | Sturgeon Bay | Wisconsin | United States | 54235 |
495 | Aurora Medical Center in Summit | Summit | Wisconsin | United States | 53066 |
496 | Aurora West Allis Medical Center | West Allis | Wisconsin | United States | 53227 |
497 | The Alyce and Elmore Kraemer Cancer Care Center | West Bend | Wisconsin | United States | 53095 |
498 | Riverview Hospital | Wisconsin Rapids | Wisconsin | United States | 54494 |
499 | Welch Cancer Center | Sheridan | Wyoming | United States | 82801 |
500 | Tom Baker Cancer Centre | Calgary | Alberta | Canada | T2N 4N2 |
501 | Cross Cancer Institute | Edmonton | Alberta | Canada | T6G 1Z2 |
502 | BCCA-Cancer Centre for the Southern Interior | Kelowna | British Columbia | Canada | V1Y 5L3 |
503 | BCCA-Vancouver Island Cancer Centre | Victoria | British Columbia | Canada | V8R 6V5 |
504 | Atlantic Health Sciences Corporation-Saint John Regional Hospital | Saint John | New Brunswick | Canada | E2L 4L2 |
505 | QEII Health Sciences Centre/Capital District Health Authority | Halifax | Nova Scotia | Canada | B3H 1V8 |
506 | Juravinski Cancer Centre at Hamilton Health Sciences | Hamilton | Ontario | Canada | L8V 5C2 |
507 | London Regional Cancer Program | London | Ontario | Canada | N6A 4L6 |
508 | Ottawa Health Research Institute-General Division | Ottawa | Ontario | Canada | K1H 1C4 |
509 | Irving Greenberg Family Cancer Centre | Ottawa | Ontario | Canada | K2H 8P4 |
510 | Thunder Bay Regional Health Science Centre | Thunder Bay | Ontario | Canada | P7B 6V4 |
511 | Odette Cancer Centre- Sunnybrook Health Sciences Centre | Toronto | Ontario | Canada | M4N 3M5 |
512 | Hopital Maisonneuve-Rosemont | Montreal | Quebec | Canada | H1T 2M4 |
513 | CHUM - Hopital Notre-Dame | Montreal | Quebec | Canada | H2L 4M1 |
514 | McGill University Department of Oncology | Montreal | Quebec | Canada | H2W 1S6 |
515 | CHU de Quebec-L'Hotel-Dieu de Quebec (HDQ) | Quebec City | Quebec | Canada | G1R 2J6 |
516 | Centre Hospitalier Universitaire de Sherbrooke-Fleurimont | Sherbrooke | Quebec | Canada | J1H 5N4 |
517 | Allan Blair Cancer Centre | Regina | Saskatchewan | Canada | S4T 7T1 |
518 | Saskatoon Cancer Centre | Saskatoon | Saskatchewan | Canada | S7N 4H4 |
Sponsors and Collaborators
- Radiation Therapy Oncology Group
- National Cancer Institute (NCI)
- NRG Oncology
Investigators
- Study Chair: Alvaro A. Martinez, MD, FACR, 21st Century Oncology - Michigan Institute for Radiation Oncology
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- RTOG 0815
- CDR0000648194
- NCI-2011-01948