QUOVADIS: QUality Of Life and surviVAl in carDIac arreSt Patients
Study Details
Study Description
Brief Summary
QUO VADIS is a national observational study with the aim to describe clinical intervention and utilization of neuroprognostication tools in the management of patients admitted to ICU following cardiac arrest
Condition or Disease | Intervention/Treatment | Phase |
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Detailed Description
Despite recent improvements in post-resuscitation care, about 50% of patients resuscitated from cardiac arrest die or have poor neurological prognosis. Post-anoxic brain injury is common after cardiac arrest and is a major cause of post-resuscitation mortality. Since there has been a significant investment in improving the emergency response to both in-hospital ad out-of-hospital cardiac arrest (IHCA and OHCA, respectevly) patients and reported improvements in short-term survival outcomes, the long-term neurological state and quality of life of survivors and their caregiver is of growing significance.
QUO VADIS is a national observational study created to describe clinical interventions and utilization of neuroprognostication tools in the management of patients admitted to ICU following cardiac arrest.
The aims of the study are:
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To create an Italian Registry that describes clinical interventions and neuroprognostication tools used in the management of patients admitted to ICU following cardiac arrest
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To evaluate, after one year from the cardiac arrest, the neurological outcome and the quality of life of the patients;
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To evaluate, after one year from the cardiac arrest, the quality of life of caregivers;
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To identify the most effective clinical intervention in the management of post-cardiac arrest patients admitted to ICU;
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To create a prognostic model for patients admitted to ICU after cardiac arrest.
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
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Cardiac arrest patients admitted to Intensive Care treatment Intensive Care treatment; Utilization of neuroprognostication tools |
Other: Intensive care treatment
Intensive care treatment; Utilization of neuroprognostication tools
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Outcome Measures
Primary Outcome Measures
- Disability [6 months]
GOSe (Glascow Outcome Scale extended). Minimum value: 1 = Dead; Maximum value: 8= Upper Good Recovery
- Neurological Outcome [6 months]
mRS (modified Ranking Scale) Minimum value: 0 = Complete recovery; Maximum value: 6 = Death
- Patients quality of life [12 months]
EuroQoL-5D (european quality of life 5 dimensions). 0 = Worst imaginable health state; 100 = best imaginable health state
Secondary Outcome Measures
- Caregiver quality of life [12 months]
Caregiver Burden Inventory. 0 to 20 = little or no burden; 61 to 88 = severe burden
Eligibility Criteria
Criteria
Inclusion Criteria:
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Age ≥ 14 years;
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Cardiac Arrest within 24 hours ICU admission
Exclusion Criteria:
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Absence of Informed consent;
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Age < 14 years
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- Gruppo Italiano per la Valutazione degli Interventi in Terapia Intensiva
Investigators
- Principal Investigator: Sergio Livigni, MD, Ospedale San Giovanni Bosco, Turin
Study Documents (Full-Text)
None provided.More Information
Additional Information:
Publications
None provided.- QUO VADIS