The Rate and Predictors of Vaginal Bleeding Among Women With Placenta Previa
Study Details
Study Description
Brief Summary
Placenta previa is usually diagnosed when the placenta implanted in the lower uterine segment, thus partially or totally overlying the internal os . It occurs with an incidence of 0.3-0.5%. It is associated mainly with prior caesarean delivery . The condition is frequently complicated by invasion of placental villi beyond the decidua basalis causing placenta accreta . Placenta previa is a major cause of massive haemorrhage during pregnancy and after delivery . The antepartum bleeding from placenta previa- can be life-threatening, thus, the prediction of this bleeding is of great importance . It is important to distinguish between women at high and low risk for antepartum haemorrhage with placenta previa especially at late pregnancy . However, the potential risk factors for antepartum haemorrhage in women with placenta previa have not been thoroughly examined.
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Study Design
Outcome Measures
Primary Outcome Measures
- The rate of vaginal bleeding in women presented by placenta previa at third trimester of pregnancy. [Through study completion, an average of 1 and half year]
The rate of vaginal bleeding in women presented by placenta previa at third trimester of pregnancy.
Secondary Outcome Measures
- Identification of the potential clinical and ultrasonographic predictors of antepartum hemorrhage in women with placenta previa at third trimester of pregnancy [through study completion, an average of 1 and half year]
The result that the investigators will get from the study will help identify predictors of antepartum hemorrhage in pregnant women with placenta previa and hence preventing it, antepartum hemorrhage is a major life threatening complication of the disease wether to the baby or the mother
Eligibility Criteria
Criteria
Inclusion Criteria:
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Pregnant women ≥ 28 weeks.
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Diagnosed to have placenta previa by ultrasound
Exclusion Criteria:
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Women with complicated pregnancies (e.g. preeclampsia, diabetes mellitus and cardiac, renal, antiphospholipid syndrome).
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Women with premature rupture of membrane.
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Women who will refuse to participate.
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- Assiut University
Investigators
- Study Chair: Kamal M Zahran, professor, department of obstetrics and gynecology, faculty of medicine, Assuit University, Egypt
- Study Director: Mohamed K Ali, doctor, department of obstetrics and gynecology, faculty of medicine, Assuit University, Egypt
- Study Director: Mohamed M Abd-allah, doctor, department of obstetrics and gynecology, faculty of medicine, Assuit University, Egypt
- Principal Investigator: Ismael O Ali, resident, department of obstetrics and gynecology, faculty of medicine, Assuit University, Egypt
Study Documents (Full-Text)
None provided.More Information
Publications
- Dashe JS. Toward consistent terminology of placental location. Semin Perinatol. 2013 Oct;37(5):375-9. doi: 10.1053/j.semperi.2013.06.017.
- Love CD, Fernando KJ, Sargent L, Hughes RG. Major placenta praevia should not preclude out-patient management. Eur J Obstet Gynecol Reprod Biol. 2004 Nov 10;117(1):24-9. doi: 10.1016/j.ejogrb.2003.10.039.
- Nagase Y, Matsuzaki S, Endo M, Hara T, Okada A, Mimura K, Hiramatsu K, Kakigano A, Nakatsuka E, Miyake T, Takiuchi T, Ueda Y, Tomimatsu T, Kimura T. Placenta previa with posterior extrauterine adhesion: clinical features and management practice. BMC Surg. 2021 Jan 6;21(1):10. doi: 10.1186/s12893-020-01027-9.
- Shaamash AH, Ali MK, Attyia KM. Intramuscular 17alpha-hydroxyprogesterone caproate to decrease preterm delivery in women with placenta praevia: a randomised controlled trial. J Obstet Gynaecol. 2020 Jul;40(5):633-638. doi: 10.1080/01443615.2019.1645099. Epub 2019 Oct 31.
- Shazly SA, Badee AY, Ali MK. The use of multiple 8 compression suturing as a novel procedure to preserve fertility in patients with placenta accreta: case series. Aust N Z J Obstet Gynaecol. 2012 Aug;52(4):395-9. doi: 10.1111/j.1479-828X.2012.01449.x. Epub 2012 Jun 9.
- Wu S, Kocherginsky M, Hibbard JU. Abnormal placentation: twenty-year analysis. Am J Obstet Gynecol. 2005 May;192(5):1458-61. doi: 10.1016/j.ajog.2004.12.074.
- placenta previa bleeding rate